Reproductive habits and fertility of indigenous cattle to artificial insemination in Uganda

1963 ◽  
Vol 60 (2) ◽  
pp. 279-284 ◽  
Author(s):  
D. H. L. Rollinson

1. Records are presented of observations of the sexual behaviour of indigenous Uganda cattle and the fertility to artificial insemination.2. The mean cycle length found was 20·9 days,s.d.1·38 days. Mean length of oestrus was 2 hr. 14 min.3. Marked pro-oestrus and metoestrus periods occurred averaging 14 hr. and 11 hr. 7 min., respectively. The mean total length of time that cows remained attractive to the bulls was 26 hr. 21 min.4. The number of services and attempts to serve by three bulls was recorded and frequent small grunts were noted to be an important expression of excitement by the bulls.5. The highest percentage of animals conceived to artificial insemination when inseminated between 15 and 25 hr. after commencement of pro-oestrus.

1964 ◽  
Vol 63 (1) ◽  
pp. 59-60 ◽  
Author(s):  
J. S. M. Hutchinson ◽  
P. J. O'Connor ◽  
H. A. Robertson

1.Within a flock of 55 Welsh Mountain ewes maintained under lowland conditions the first ewe came into oestrus on the 14th October. The mean cycle length of 44 normal cycles was 16 days 3 hr.2. The onset of oestrus as assessed by the time of mounting of the ram does not appear to be evenly distributed throughout the day (24 hr.).


1969 ◽  
Vol 61 (3) ◽  
pp. 494-508 ◽  
Author(s):  
Rolf Plesner

ABSTRACT The author reports the results of a clinical study on 17 fertile women treated through a total of 120 cycles with Deladroxate, an injectable, long-acting oestrogen-progestogen. The injections were administered on the 8th (7th–9th) day of each cycle. Before treatment was started, the patients were observed through 2 cycles with regard to cycle length as well as duration and amount of flow. Moreover, ovulation was assessed by means of daily recording of basal body temperature (BBT), pregnanediol analyses, total pituitary gonadotrophin analyses, and endometrial biopsies. In some cases the dosage had to be increased because of a shortening of the cycle. The mean cycle length during the treatment was 24.2 days, though with fairly marked variations (mean cycle length before institution of treatment: 28.2 days). Duration of flow ranged from 3–35 days. About 84% of 108 withdrawal bleedings lasted for 4–8 days. Of the flows 56 % were of normal amount, while the majority of the remaining 44 % were scantier than in the patients with normal periods. The ovulation-inhibiting effect of Deladroxate was assessed by daily recording of BBT, pregnanediol and pituitary gonadotrophin assays, and endometrial biopsies. Five of the 41 BBT curves (41 cycles) were biphasic. Four out of 34 endometrial biopsies, obtained on the 23rd day of the cycle, showed a secretory phase. Forty out of 41 cycles were anovulatory, as assessed by the pregnanediol excretion, while in 1 cycle the excretion pattern was not characteristic. In 20 out of 37 cycles there was a definite depression of gonadotrophin excretion, while in 17 cycles the excretion pattern was not characteristic. The effect of Deladroxate on the adrenal cortex was studied by means of 17-ketogenic steroid and 17-ketosteroid excretion. With both groups of steroids there seemed to be a tendency to a reduced excretion during treatment. No changes in the fibrinogen, prothrombin, GO-transaminase, bilirubin, or thymol values were observed during treatment. Side effects during treatment, recorded in 11 of the 17 subjects, were in most cases slight and transient. The most common complaints were breast tenderness, oedema, and irregularities of bleeding. No pregnancy occurred during treatment.


1972 ◽  
Vol 4 (4) ◽  
pp. 371-378 ◽  
Author(s):  
William H. James

The length of the post-ovulatory phase in a composite sample of menstrual cycles increases linearly with cycle length until cycle length reaches about 30 days, but thereafter it ceases to increase (Vollman, 1953; Bailey & Marshall, 1970). By contrast, plotted against the mean cycle length of the individual, the length of the post-ovulatory phase continues to increase roughly linearly with mean cycle length. It is concluded (a) that many long cycles are aberrant occurrences among cycles of normal length and are due to lengthening of the pre-ovulatory phase and (b) that where the mean cycle length is long, ovulation, as in shorter cycles, occurs just before the middle of the cycle, so that the post-ovulatory phase is longer than usual.The most fertile day seems to be the one before mid-cycle. These conclusions are the basis for the following formula for calendar rhythm:If x is the shortest and y the longest cycle in a woman's menstrual record, the ‘unsafe’ days start on Day (½x − 5) and last for (y − x + 8) days.


1981 ◽  
Vol 15 (4) ◽  
pp. 351-353 ◽  
Author(s):  
G. B. Blakley ◽  
T. W. Beamer ◽  
W. R. Dukelow

The events of the perineal swelling cycle in Macaca nemestrina have been correlated with the optimal time for conception. The mean cycle length of the animals was 32·8 days with the follicular and luteal phases of the cycle 17·6-19·2 and 13·6-15·2 days respectively. The time of ovulation, relative to the tumescence peak, ranged from 1 to 13 days. The optimal time for mating, based on the ratio between day of breeding and cycle length was 0·46, a value comparable with similar calculations for other macaque species.


Lactation in the rat can be prolonged indefinitely by the provision of a succession of young foster fitters to continue the stimulus of suckling. Under these conditions lactation becomes a steady state. In three rats nursing their third or fourth litters, lactation was so maintained for periods of 9, 10 and 12 months, respectively, and failure occurred only after the experimental conditions were deliberately altered. To attain steady lactation, foster litters were nursed only for the last few days of the period during which they depend wholly on the mother, i.e. shortly before their eyes open, and thus furnish a strong suckling stimulus not varying too greatly at each exchange of foster litter. In these circumstances sufficient milk was being secreted continuously to increase litter weight by 9 to 10 g per day (figure 49). The oestrous cycle was prolonged, the mean cycle length for the three females during prolonged lactation being 17.8 days. This condition has been described by Selye (1934) as ‘suckling pseudo-pregnancy'. In other experiments with prolonged lactation mating was allowed to take place after periods varying from 50 to 106 days of continuous lactation. There was no diminution of milk production as judged by litter growth over the night of mating if the male was introduced into the female’s cage and the young allowed to remain so that suckling continued. Neither was there a delay in implantation such as occurs after a mating at post-partum oestrus in the presence of a suckling litter, parturition occurring after the normal gestation period of 22 to 23 days (five out of five females).


1970 ◽  
Vol 65 (4) ◽  
pp. 683-697 ◽  
Author(s):  
Rolf Plesner

ABSTRACT The results of a clinical investigation on 22 fertile women treated cyclically with a total of 341 injections of Deladroxate, an injectable, long-acting oestrogen-progestogen are presented. The injections were administered on the 8th (7th–9th) day of each cycle. Before treatment, the patients were observed through 2 cycles for cycle length as well as duration and amount of flow. In some cases the dose was increased because of a shortening of the cycle. The over all mean cycle length during the treatment was 25.3 days, though with fairly marked variations. The mean cycle length before treatment was 28.4 days. The duration of flow ranged from 1–30 days. About 72% of 320 withdrawal bleedings lasted for 4–8 days. Of the flows 60% were of normal amounts, while the majority of the remaining flows were scantier than the normal pre-treatment flows of the subjects. Side effects during treatment were recorded in one or more cycles in 17 of the 22 subjects and were in most cases slight and transient. The most common complaints were breast tenderness, oedema, and irregularities of bleeding. No pregnancy occurred during treatment. After discontinuation of the injections, bleedings and cycles normalized spontaneously in 11 women. In 1 woman curettage was performed because of profuse flow, and 2 women were treated with oral oestrogen-progestogens because of persistent bleeding. Eight women started oral contraception before the cycles became regular.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Javier Jiménez-Candil ◽  
Olga Duran ◽  
Armando Oterino ◽  
Jendri Pérez ◽  
Juan Carlos Castro ◽  
...  

Abstract Background ICD patients with episodes of nonsustained ventricular tachycardias (NSVT) are at risk of appropriate therapies. However, the relationship between the cycle length (CL) of such NSVTs and the subsequent incidence of appropriate interventions is unknown. Methods 416 ICD patients with LVEF < 45% were studied. ICD programming was standardized. NSVT was defined as any VT of 5 or more beats at ≥ 150 bpm occurred in the first 6 months after implantation that terminated spontaneously and was not preceded by any appropriate therapy. The mean follow-up was 41 ± 27 months. Results We analyzed 2201 NSVTs (mean CL = 323 ms) that occurred in 250 patients; 111 of such episodes were fast (CL ≤ 300 ms). Secondary prevention (HR = 1.7; p < 0.001), number of NSVT episodes (HR = 1.05; 95% CI 1.04–1.07; p < 0.001) and beta-blocker treatment (HR = 0.7; p = 0.04) were independent predictors of appropriate interventions; however, the mean CL of NSVTs was not (p = 0.6). There was a correlation between the mean CL of NSVTs and the CL of the first monomorphic VT: r = 0.88; p < 0.001. This correlation was especially robust in individuals with > 5 NSVTs (r = 0.97; p < 0.001), with an agreement between both values greater than 95%. Patients with any fast NSVT experienced a higher incidence of VF episodes (26%) compared to those without NVSTs (3%) or with only slow NSVTs (7%); p < 0.001. Conclusions Unlike the burden, the CL of NSVTs is not a predictor of subsequent appropriate interventions. However, there is a close relationship between the CL of NSVTs and that of arrhythmias that will later lead to appropriate therapies.


2021 ◽  
Author(s):  
Anne-Marie Begin

&lt;p&gt;To estimate the impact of climate change on our society we need to use climate projections based on numerical models. These models make it possible to assess the effects on climate of the increase in greenhouse gases (GHG) as well as natural variability. We know that the global average temperature will increase and that the occurrence, intensity and spatio-temporal distribution of extreme precipitations will change. These extreme weather events cause droughts, floods and other natural disasters that have significant consequences on our life and environment. Precipitation is a key variable in adapting to climate change.&lt;/p&gt;&lt;p&gt;&amp;#160;&lt;/p&gt;&lt;p&gt;This study focuses on the ClimEx large ensemble, a set of 50 independent simulations created to study the effect of climate change and natural variability on the water network in Quebec. This dataset consists of simulations produced using the Canadian Regional Climate Model version 5 (CRCM5) at 12 km of resolution driven by simulations from the second generation Canadian Earth System Model (CanESM2) global model at 310 km of resolution.&lt;/p&gt;&lt;p&gt;&amp;#160;&lt;/p&gt;&lt;p&gt;The aim of the project is to evaluate the performance of the ClimEx ensemble in simulating the daily cycle and representing extreme values.&amp;#160; To get there, 30 years of hourly time series for precipitation and 3 hourly for temperature are analyzed. The simulations are compared with the values from the simulation of CRCM5 driven by ERA-Interim reanalysis, the ERA5 reanalysis and Environment and Climate Change Canada (ECCC) stations. An evaluation of the sensitivity of different statistics to the number of members is also performed.&lt;/p&gt;&lt;p&gt;&amp;#160;&lt;/p&gt;&lt;p&gt;The daily cycle of precipitation from ClimEx shows mainly non-significant correlations with the other datasets and its amplitude is less than the observation datas from ECCC stations. For temperature, the correlation is strong and the amplitude of the cycle is similar to observations. ClimEx provides a fairly good representation of the 95, 97, 99&lt;sup&gt;th&lt;/sup&gt; quantiles for precipitation. For temperature it represents a good distribution of quantiles but with a warm bias in southern Quebec. For precipitation hourly maximum, ClimEx shows values 10 times higher than ERA5.&amp;#160; For temperature, minimum and maximum values may exceed the ERA5 limit by up to 20&amp;#176;C. For precipitation, the minimum number of members for the estimation of the 95 and 99&lt;sup&gt;th&lt;/sup&gt;&lt;sup&gt;&lt;/sup&gt;quantiles and the mean cycle is between 15 and 50 for an estimation error of less than 5%. For the 95, 99&lt;sup&gt;th&lt;/sup&gt; quantiles of temperature, the minimum number of members is between 1 and 17 and for the mean cycle 1 to 2 members are necessary to obtain an estimation error of less than 0.5&amp;#176;C.&lt;/p&gt;


2018 ◽  
Vol 128 (6) ◽  
pp. 1792-1798 ◽  
Author(s):  
Gurpreet S. Gandhoke ◽  
Yash K. Pandya ◽  
Ashutosh P. Jadhav ◽  
Tudor Jovin ◽  
Robert M. Friedlander ◽  
...  

OBJECTIVEThe price of coils used for intracranial aneurysm embolization has continued to rise despite an increase in competition in the marketplace. Coils on the US market range in list price from $500 to $3000. The purpose of this study was to investigate potential cost savings with the use of a price capitation model.METHODSThe authors built a clinical decision analytical tree and compared their institution’s current expenditure on endovascular coils to the costs if a capped-price model were implemented. They retrospectively reviewed coil and cost data for 148 patients who underwent coil embolization from January 2015 through September 2016. Data on the length and number of coils used in all patients were collected and analyzed. The probabilities of a treated aneurysm being ≤/> 10 mm in maximum dimension, the total number of coils used for a case being ≤/> 5, and the total length of coils used for a case being ≤/> 50 cm were calculated, as was the mean cost of the currently used coils for all possible combinations of events with these probabilities. Using the same probabilities, the authors calculated the expected value of the capped-price strategy in comparison with the current one. They also conducted multiple 1-way sensitivity analyses by applying plausible ranges to the probabilities and cost variables. The robustness of the results was confirmed by applying individual distributions to all studied variables and conducting probabilistic sensitivity analysis.RESULTSNinety-five (64%) of 148 patients presented with a rupture, and 53 (36%) were treated on an elective basis. The mean aneurysm size was 6.7 mm. A total of 1061 coils were used from a total of 4 different providers. Companies A (72%) and B (16%) accounted for the major share of coil consumption. The mean number of coils per case was 7.3. The mean cost per case (for all coils) was $10,434. The median total length of coils used, for all coils, was 42 cm. The calculated probability of treating an aneurysm less than 10 mm in maximum dimension was 0.83, for using 5 coils or fewer per case it was 0.42, and for coil length of 50 cm or less it was 0.89. The expected cost per case with the capped policy was calculated to be $4000, a cost savings of $6564 in comparison with using the price of Company A. Multiple 1-way sensitivity analyses revealed that the capped policy was cost saving if its cost was less than $10,500. In probabilistic sensitivity analyses, the lowest cost difference between current and capped policies was $2750.CONCLUSIONSIn comparison with the cost of coils from the authors’ current provider, their decision model and probabilistic sensitivity analysis predicted a minimum $407,000 to a maximum $1,799,976 cost savings in 148 cases by adapting the capped-price policy for coils.


2021 ◽  
Vol 28 (1) ◽  
pp. 78-83
Author(s):  
O. O. ONI ◽  
N. I. DIM ◽  
B. Y. ABUBAKAR ◽  
O. E. ASIRIBO

Data on the monthly egg production of a strain of Rhode Island chickens (500 breeder hens) were used to test the goodness of fit of six mathematical models, viz; Exponential, Parabolic exponential, Wood's Gamma type and modified Gamma type by McNally, Inverse polynomial and Linear regression. Egg production was summarized for each hen into 28-d periods, starting from the day of firts egg. The hens were classified into different production cycle length based on the number of 28-d periods. The models were fitted to the mean results obtained for periods within groups of hens. The effect of cycle length on goodness of fit was also examined separately for the 'best' three models with highest R2 values. The egg production cycle (i.e. number of 28-d periods) varied from 9 to 15 periods. Similarly, the coefficients of determination (R2) varied from 0.16 to 0.95 from fitting the models to mean egg production data for groups of hens. The results suggest that thye 'best' three models that were chosen fitted 52 week laying records quite well, judging from their respective R2, which were higherf for McNally (0.95) and Parabolic exponential (0.93) than for wood (0.75). Based on the goodness of fit to 52-week production record, the McNally model gave the best results. However, its suitability in predicting full year production from part year record needs to be further investigated.


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