Urbanization and human health

Parasitology ◽  
1993 ◽  
Vol 106 (S1) ◽  
pp. S93-S107 ◽  
Author(s):  
D.R. Phillips

SUMMARYUrbanization involves a physical change in which increasing proportions of populations live in urban settings, however defined. It also implies considerable changes in the ways in which these people live, how they earn their livelihoods, the food which they eat, and the wide range of environmental factors to which they are exposed. There is another underlying assumption that, increasingly, urban populations will be more healthy than their rural counterparts and that higher levels of urbanization will equate with better health status. This paper discusses some of the assumptions underlying this contention. It takes issue with certain of them, particularly the assumption that urbanization affects the health of all residents equally. It is manifestly evident that in many cities, particularly in the developing world, the poor are exposed to greater risks and have much lower health status than their richer neighbours. In addition, whilst urban residents may theoretically have a better access to health care and services than do residents in many rural areas, and whilst many indicators of health do appear better in more highly urbanized societies than ones less so, there are caveats. The paper introduces the concept of epidemiological transition, which suggests that, whilst life expectancy might be higher in many urbanized countries and in certain cities, the inhabitants are often merely suffering from different forms of ill-health, often chronic or degenerative, rather than infective. In certain cities in middle-income countries, residents, particularly the poor, are exposed to a double risk of both infection and chronic degenerative ailments. The paper concludes with a consideration of more general recent statements from the World Health Organization among others, on the impact of urbanization on health. The ‘Healthy Cities’ project is also discussed. WHO identifies a range of general determinants of urban health: physical, social, cultural and environmental. Many represent the by-products of modernization and especially industrialization. It is emphasized that urbanization, and the concentration of human beings into new areas in particular, can bring exposure to new risk factors for large numbers of people. The growth of infectious and parasitic disease in some urban settings must therefore be recognized, as must the emergence of chronic diseases, with the concomitant need for investment in new types of health and social care. However, a number of constraints militate against the achievement of improved urban health, especially in developing countries. The paper concludes by considering some important constraints: the very scale of urban health problems; the impacts of structural adjustment programmes which cut public expenditure on environmental health, health services and nutrition, thereby increasing the vulnerability of the poor; urban management problems; lack of political will; and the difficulties of measuring change in health and effects of policies.

Toxins ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 451
Author(s):  
José María Gutiérrez ◽  
Laura-Oana Albulescu ◽  
Rachel H. Clare ◽  
Nicholas R. Casewell ◽  
Tarek Mohamed Abd Abd El-Aziz ◽  
...  

A global strategy, under the coordination of the World Health Organization, is being unfolded to reduce the impact of snakebite envenoming. One of the pillars of this strategy is to ensure safe and effective treatments. The mainstay in the therapy of snakebite envenoming is the administration of animal-derived antivenoms. In addition, new therapeutic options are being explored, including recombinant antibodies and natural and synthetic toxin inhibitors. In this review, snake venom toxins are classified in terms of their abundance and toxicity, and priority actions are being proposed in the search for snake venom metalloproteinase (SVMP), phospholipase A2 (PLA2), three-finger toxin (3FTx), and serine proteinase (SVSP) inhibitors. Natural inhibitors include compounds isolated from plants, animal sera, and mast cells, whereas synthetic inhibitors comprise a wide range of molecules of a variable chemical nature. Some of the most promising inhibitors, especially SVMP and PLA2 inhibitors, have been developed for other diseases and are being repurposed for snakebite envenoming. In addition, the search for drugs aimed at controlling endogenous processes generated in the course of envenoming is being pursued. The present review summarizes some of the most promising developments in this field and discusses issues that need to be considered for the effective translation of this knowledge to improve therapies for tackling snakebite envenoming.


2021 ◽  
Vol 19 ◽  
Author(s):  
Mohamed Said Boulkrane ◽  
Victoria Ilina ◽  
Roman Melchakov ◽  
Mikhail Arisov ◽  
Julia Fedotova ◽  
...  

: The World Health Organization declared the pandemic situation caused by SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus-2) in March 2020, but the detailed pathophysiological mechanisms of Coronavirus disease 2019 (COVID-19) are not yet completely understood. Therefore, to date, few therapeutic options are available for patients with mild-moderate or serious disease. In addition to systemic and respiratory symptoms, several reports have documented various neurological symptoms and impairments of mental health. The current review aims to provide the available evidence about the effects of SARS-CoV-2 infection on mental health. The present data suggest that SARS-CoV-2 produces a wide range of impairments and disorders of the brain. However, a limited number of studies investigated the neuroinvasive potential of SARS-CoV-2. Although the main features and outcomes of COVID-19 are linked to severe acute respiratory illness. The possible damages on the brain should be considered, too.


2021 ◽  
Vol 13 (21) ◽  
pp. 12225
Author(s):  
Silvio Cristiano ◽  
Samuele Zilio

An increasing interest has been present in scientific literature and policy making for the links between urban environments and health, as also learnt from the COVID-19 pandemic. Collaboration between urban planning and public health is therefore critical for enhancing the capabilities of a city to promote the well-being of its people. However, what leverage potential for urban health can be found in existing plans, policies, and strategies that address urban health? Starting from the relationship between urban systems and health issues, the purpose of this contribution is to broaden the systemic knowledge of urban systems and health so as to try to figure out the impact potential of local urban governance on public health. Considering the systemic nature of health issues, as defined by the World Health Organisation, this is done through a systems thinking epistemological approach. Urban health proposals are studied and assessed in four European cities (Copenhagen, London, Berlin, and Vienna). Current criticalities are found, starting from the guiding goal of such proposals, yet a systemic approach is suggested aimed at supporting and evaluating lasting and healthy urban planning and management strategies.


2020 ◽  
Vol 3 (2) ◽  
pp. 50
Author(s):  
Tea Kasradze

Financial inclusion is often considered as an access to financial resources for the wide public and small and medium-sized businesses, although it is a much broader concept and includes a wide range of access to quality financial products and services, including loans, deposit services, insurance, pensions and payment systems. Mechanisms for protecting the rights of consumers of financial products and services are also considered to be subject to financial inclusion. Financial inclusion acquires great importance during the pandemic and post-pandemic period. The economic crisis caused by the pandemic is particularly painful for low-income vulnerable population. A large part of the poor population who were working informally has lost source of income due to lockdown from the pandemic. Remittances have also been reduced / minimized, as the remitters had also lost jobs and are unable to send money home. Today, when people die from Coronavirus disease, it may be awkward to talk about the financial side of a pandemic, but the financial consequences can be far-reaching if steps are not taken today to ensure access to and inclusion of financial resources. The paper examines the impact of the pandemic on financial inclusion and the responses of the governments and the financial sectors to the challenge of ensuring the financial inclusion of the poor population and small and medium enterprises.


Author(s):  
Samuel Torvend

Luther not only wrote about charity and social ethics throughout much of his life; he also experienced the conditions that were the object of Christian generosity and ethical reflection. This essay suggests that his study of the Bible and Church Fathers was not the only source of Luther’s writings and revolutionary programs. His experience of deprivation as a child and a monk, his encounters with the homeless poor of Wittenberg, and his observation of corrupt business practices and failed political leadership played significant roles in his sensitivity to the scriptures and the history of ecclesial care for the poor. The rise of social history and the use of social scientific methods have drawn attention to the economic, political, and social context in which Luther lived and to which he responded throughout his life. The reformer’s works on charity and social ethics did not emerge in a vacuum. His initial public foray focused on the “spiritual economy” of the late medieval church, which discriminated against many of Luther’s poor parishioners. While the Ninety-Five Theses raised serious questions about the sacrament of penance, the role of indulgences, and the authority of the pope, the text also reveals Luther’s early concern for the poor, who were frightened into buying spiritual favors for themselves or their dead relatives. In addition to theological problems, Luther recognized the ethical dimension of this large-scale sales campaign that benefited archbishops and the Vatican treasury. Luther’s rediscovery of the Pauline teaching on justification by grace alone reoriented Christians toward life in this world. Rather than spend effort or money on spiritual exercises that might win one God’s favor in the afterlife, human energies could be directed toward alleviating present suffering. A dialectical thinker, Luther insisted on holding together two seemingly irreconcilable claims, two disparate texts, two discordant images in order to raise the question: How is one related to the other? His teaching on justification claims that God always advances toward a suffering humanity first and that this advance is revealed with utter clarity in the person and work of Jesus Christ, who incarnates God’s desire to free human beings from the deathly presence of anxious religion and give them “life, health, and salvation.” But such freedom must be used for the good of one’s neighbor who suffers within the economic, political, and social fabric of life. The advance of God, who is mercy and grace, continues into the world through Christ and his body. This essay suggests that while Luther animated significant contributions to biblical studies and theology, a body of ethical teaching has been harder to discern among his followers. Perhaps this hesitancy arose out of fear that an emphasis on ethics would be construed as a lapse into what Luther called “works righteousness.” This essay considers a number of the ethical questions and crises that faced Luther, which have not subsided and ask for contemporary investigation. A remarkable achievement of Luther’s reform was a revolutionary change in social assistance. The monastic communities of western Europe had long served as centers of hospitality and charity, and the order in which the young Luther made his vows was a reforming order committed to austerity of life and care for the urban poor. For theological reasons, Luther promoted the suppression of the monasteries and vilified the mendicant orders, but this left a gap in care for the growing population of homeless peasants seeking work in urban centers. The reform of social assistance undertaken in the small “Lutheran” town of Leisnig, Germany, in the early 16th century would become the model for many church orders throughout Germany and Scandinavia, influencing today’s state-run and tax-funded assistance to needy families. Recently, ethicists and Luther scholars have reassessed his reform of charity to ask how the reformer’s social teaching might support engagement with a wide range of present-day social movements. Increased study of Luther’s social writings and the study of evangelical “church orders,” previously marginalized in the academy, offers promising avenues for continued research. This essay also compares three forms of charity—Lutheran, Roman Catholic, and Reformed—illustrating the symbiotic relationship between social ethics and theology and underscoring the role of theological priorities in the conceptualization of social assistance. Finally, this essay considers Luther’s writings on social ethics. Frequently, interpreters of this focus on “faith active in love,” or the utility of his distinction between two kingdoms or governments. Such studies offer a biblical or theological grounding for Lutheran ethics yet frequently overlook the actual crises or practices he encountered. Luther was not a “systematic” theologian, and one must search through his many writings to discover his “ethical” teachings. Luther scholars and historians of social ethics are increasingly interested in the specific ethical questions he was asked to discuss by those who had accepted his reform. The growing popularity of his reform movement and the seismic shift in Christian thought and practice it animated left Luther little time to construct a well-ordered corpus of social teaching, yet many of his concerns are vitally alive in the world today albeit within a different context. Many of his concerns were enlightened by his study of scripture, in which he recognized a mirror of his own turbulent era.


BMJ Open ◽  
2019 ◽  
Vol 9 (8) ◽  
pp. e029789 ◽  
Author(s):  
Claire Louise Hutchinson ◽  
Angela Berndt ◽  
Deborah Forsythe ◽  
Susan Gilbert-Hunt ◽  
Stacey George ◽  
...  

ObjectivesTo identify how social return on investment (SROI) analysis—traditionally used by business consultants—has been interpreted, used and innovated by academics in the health and social care sector and to assess the quality of peer-reviewed SROI studies in this sector.DesignSystematic review.SettingsCommunity and residential settings.ParticipantsA wide range of demographic groups and age groups.ResultsThe following databases were searched: Web of Science, Scopus, CINAHL, Econlit, Medline, PsychINFO, Embase, Emerald, Social Care Online and the National Institute for Health and Care Excellence. Limited uptake of SROI methodology by academics was found in the health and social care sector. From 868 papers screened, 8 studies met the criteria for inclusion in this systematic review. Study quality was found to be highly variable, ranging from 38% to 90% based on scores from a purpose-designed quality assessment tool. In general, relatively high consistency and clarity was observed in the reporting of the research question, reasons for using this methodology and justifying the need for the study. However, weaknesses were observed in other areas including justifying stakeholders, reporting sample sizes, undertaking sensitivity analysis and reporting unexpected or negative outcomes. Most papers cited links to additional materials to aid in reporting. There was little evidence that academics had innovated or advanced the methodology beyond that outlined in a much-cited SROI guide.ConclusionAcademics have thus far been slow to adopt SROI methodology in the evaluation of health and social care interventions, and there is little evidence of innovation and development of the methodology. The word count requirements of peer-reviewed journals may make it difficult for authors to be fully transparent about the details of their studies, potentially impacting the quality of reporting in those studies published in these journals.PROSPERO registration numberCRD42018080195.


Water ◽  
2020 ◽  
Vol 12 (2) ◽  
pp. 612 ◽  
Author(s):  
Monia Renzi ◽  
Valentina H. Pauna ◽  
Francesca Provenza ◽  
Cristina Munari ◽  
Michele Mistri

Transitional water ecosystems (TWEs), despite their ecological and economic importance, are largely affected by human pressures that could be responsible for significant inputs of litter in the marine environment. Plastic input in coastal ponds, lagoons, river deltas and estuaries, could be driven by a wide range of human activities such as agriculture, waste disposal, municipal and industrial wastewater effluents, aquaculture, fishing and touristic activities and urban impacts. However, it remains unknown what the impact of plastic input in these TWEs could have on natural capital and, therefore, the ability for an ecosystem to provide goods and services to human beings. Given the large interest with regards to the conservation of transitional water ecosystems and the clear exposure risk to plastic and microplastic pollution, this study aims to perform: (i) a bibliometric analyses on existing literature regarding the levels of marine litter in such environments; (ii) a selection among the available literature of homogeneous data; and (iii) statistical analyses to explore data variability. Results suggest that: (i) research on microplastics in these ecosystems did not begin to be published until 2013 for lagoons, 2014 for river mouths and 2019 for coastal ponds. The majority of articles published on studies of microplastics in lagoons did not occur until 2019; (ii) sediments represent the matrix on which sampling and extraction variability allow the statistical analyses on data reported by the literature; (iii) the Analysis of Similarities (ANOSIM) test two-way evidenced that the level of protection of marine and terrestrial areas produced similar values while the habitat type showed low significance in terms of its effect on microplastic levels, shape and size in sediments.


2020 ◽  
Author(s):  
Robin Jérémy ◽  
Latessa Pablo Gaston ◽  
Manousos Valyrakis

<p>Several studies have documented high concentration of microplastics on fresh water sources, oceans and even on treated tap and bottled water. Understanding the physics behind these particles in the water environment has become one of the key research needs identified in the World Health Organization Report (2019). In order to develop novel and efficient methodologies for sampling, treating and removing microplastics from water bodies, a thorough understanding of the sources and transportation and storage mechanisms of these particles is required.</p><p>In this article, the settlement velocity affecting the transport [1, 2] of low-density particles (1<r<1.4 g.cm<sup>-3</sup>) and drag coefficients is assessed through numerical modelling. The effects of fluid and particle relative densities and media temperatures are analysed, as well as the impact of the particle size and shapes [3].</p><p>Computational Fluid Dynamics (CFD) techniques are applied to solve the fluid dynamics while the Discrete Element Method (DEM) approach is used to model the particle trajectories [4]. These two modules are coupled under the CFDEM module, which transmits the forces from the fluid into the particle and from the particle into the surrounding water through the Fictitious Boundary Method approach.</p><p>Several tests are run under the same particle conditions in order to estimate the influence of turbulent flows on these experiments. The influence from different particle densities and diameters on settling velocities and drag coefficients is assessed. The numerical results are validated against a wide range of experimental data [2, 3] and compared against empirical predictions.</p><p>There is an urge for gaining a better understanding of the sources and transport of microplastics through fresh water bodies. In this sense, sampling and quantification of microplastics in a drinking water source is key to evaluate the environment status and to design the most appropriate techniques to reduce or remove the microplastics from the aquatic environments. The implementation of coupled CFD-DEM models provides a very powerful tool for the understanding and prediction of the transport processes and the accumulation of microplastics along the fluvial vectors.</p><p> </p><p>References</p><p>[1] Valyrakis M., Diplas P. and Dancey C.L. 2013. Entrainment of coarse particles in turbulent flows: An energy approach. J. Geophys. Res. Earth Surf., Vol. 118, No. 1., pp 42- 53, doi:340210.1029/2012JF002354.</p><p>[2] Valyrakis, M., Farhadi, H. 2017. Investigating coarse sediment particles transport using PTV and “smart-pebbles” instrumented with inertial sensors, EGU General Assembly 2017, Vienna, Austria, 23-28 April 2017, id. 9980.</p><p>[3] Valyrakis, M., J. Kh. Al-Hinai, D. Liu (2018), Transport of floating plastics along a channel with a vegetated riverbank, 12th International Symposium on Ecohydraulics, Tokyo, Japan, August 19-24, 2018, a11_2705647.</p><p>[4] Valyrakis M., P. Diplas, C.L. Dancey, and A.O. Celik. 2008. Investigation of evolution of gravel river bed microforms using a simplified Discrete Particle Model, International Conference on Fluvial Hydraulics River Flow 2008, Ismir, Turkey, 03-05 September 2008, 10p.</p>


2021 ◽  
Vol 12 ◽  
Author(s):  
Nina Obbarius ◽  
Felix Fischer ◽  
Gregor Liegl ◽  
Alexander Obbarius ◽  
Matthias Rose

BackgroundStress is a major risk factor for the impairment of psychological well-being. The present study aimed to evaluate the empirical evidence of the Transactional Stress Model proposed by Lazarus and Folkman in patients with psychosomatic health conditions.MethodsA structural equation model was applied in two separate subsamples of inpatients from the Department of Psychosomatic Medicine (total n = 2,216) for consecutive model building (sample 1, n = 1,129) and confirmatory analyses (sample 2, n = 1,087) using self-reported health status information about perceived stress, personal resources, coping mechanisms, stress response, and psychological well-being.ResultsThe initial model was created to reflect the theoretical assumptions by Lazarus and Folkman about their transactional stress concept. This model was modified until a sufficient model fit was reached (sample 1: CFI = 0.904, TLI = 0.898, RMSEA = 0.072 [0.071–0.074], SRMR = 0.061). The modified model was confirmed in a second sample (sample 2: CFI = 0.932, TLI = 0.928, RMSEA = 0.066 [0.065–0.068], SRMR = 0.052). Perceived external stressors and personal resources explained 91% of the variance of the stress response, which was closely related to symptoms of depression (63% variance explained). The attenuating effect of resources on stress response was higher (standardized β = -0.73, p < 0.001) than the impact of perceived stressors on stress response (standardized β = 0.34, p < 0.001).ConclusionThe empirical data largely confirmed the theoretical assumption of the Transactional Stress Model, which was first presented by Lazarus and Folkman, in patients with a wide range of psychosomatic conditions. However, data analyses were solely based on self-reported health status. Thus, proposed inner psychological mechanisms such as the appraisal process could not be included in this empirical validation. The operationalization and understanding of coping processes should be further improved.


Coronavirus disease (COVID-19) has been declared a pandemic by the World Health Organization on the 11th March 2020. COVID-19 has a wide range of effects. Increased Covid-19 infection is a major risk factor due to human unconsciousness and disobedience. The effects are increasing gradually. Therefore, the Bangladesh government has imposed a lockdown, but the outcome is adverse to this lockdown. It has shown us the real situation in our economic, social, education, service, and health sectors. It reveals, in particular, that, as a result of Covid-19, our health sector, which is a basic human need, has entirely broken down, and that, as a result of the epidemic, our educational system has also been impacted. Generally speaking, the education sector will suffer significant damage. Our main purpose in this paper is to show the impact of Covid-19 on different sectors of our country.


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