scholarly journals Prevalence, risk factors and antimicrobial resistance ofSalmonelladiarrhoeal infection among children in Thi-Qar Governorate, Iraq

2017 ◽  
Vol 145 (16) ◽  
pp. 3486-3496 ◽  
Author(s):  
A. HARB ◽  
M. O'DEA ◽  
Z. K. HANAN ◽  
S. ABRAHAM ◽  
I. HABIB
Keyword(s):  
Risk Factors ◽  
Antimicrobial Resistance ◽  
Tertiary Education ◽  
Epidemiological Data ◽  
Cross Sectional Study ◽  
Stool Culture ◽  
Multivariable Logistic Regression Analysis ◽  
Cross Sectional ◽  
Education Levels ◽  
Culture Positive

SUMMARYWe conducted a hospital-based cross-sectional study among children aged <5 years in Thi-Qar Governorate, south-eastern Iraq, in order to examine the prevalence, risk factors and antimicrobial resistance associated with gastroenteritis caused bySalmonellainfection. From 320 diarrhoea cases enrolled between March and August 2016, 33 (10·3%, 95% confidence interval (CI) 8·4–12·4) cases were stool culture-positive for non-typhoidalSalmonella enterica. The most commonly identified serovar was Typhimurium (54%). Multivariable logistic regression analysis indicated that the odds ofSalmonellainfection in children from households supplied by pipe water was 4·7 (95% CI 1·6–13·9) times higher compared with those supplied with reverse osmosis treated water. Similarly, children from households with domestic animals were found to have a higher odds (OR 10·5; 95% CI 3·8–28·4) of beingSalmonellastool culture-positive. The likelihood ofSalmonellainfection was higher (OR 3·9; 95% CI 1·0–6·4) among children belonging to caregiver with primaryvs. tertiary education levels. Lower odds (OR 0·4; 95% CI 0·1–0·9) ofSalmonellainfection were associated with children exclusively breast fed as compared with those exclusively bottle fed.Salmonellainfection was three times lower (95% CI 0·1–0·7) in children belonging to caregiver who reported always washing hands after cleaning children following defecation,vs.those belonging to caregivers who did not wash hands. The antimicrobial resistance profile by disc diffusion revealed that non-susceptibility to tetracycline (78·8%), azithromycin (66·7%) and ciprofloxacin (57·6%) were the most commonly seen, and 84·9% ofSalmonellaisolates were classified as multi-drug resistant. This is the first study on prevalence and antimicrobial resistance ofSalmonellainfection among children in this setting. This work provides specific epidemiological data which are crucial to understand and combat paediatric diarrhoea in Iraq.

scholarly journals Dietary Factors of blaNDM Carriage in Health Community Population: A Cross-Sectional Study

2021 ◽  
Vol 18 (11) ◽  
pp. 5959
Author(s):  
Shuangfang Hu ◽  
Ziquan Lv ◽  
Qiumei Xiang ◽  
Yang Wang ◽  
Jianzhong Shen ◽  
...  
Keyword(s):  
Risk Factors ◽  
Antimicrobial Resistance ◽  
Cross Sectional Study ◽  
Dietary Factors ◽  
Coarse Grain ◽  
Sectional Study ◽  
Cross Sectional ◽  
Health Community ◽  
Health Communities ◽  
Tuber Crops

Aim: There is an ongoing debate as to what extent antimicrobial resistance (AMR) can be transmitted from dietary to humans via the consumption of food products. We investigated this association between dietary and global spreading carbapenem-resistant gene blaNDM Methods: We did a cross-sectional study to assess the risk factors for carrier of blaNDM in health community. Healthy adults were recruited from the residents attending Community Healthcare Service in Shenzhen City (Guangdong Province, China), through 1February 2018 to 31December 2019, and 718 pre-participants were included in this study. Questionnaire were obtained and the qualitative food frequency questionnaire (Q-FFQ) were used to assess dietary intake. qPCR was applied to confirm the carrier of blaNDM in participants’fecal samples. Multivariable logistic regression was used to estimate the odds ratio (OR) and 95% confidence interval (95% CI) of each outcome according to each dietary factor before and after prosperity score matching (PSM). Results: we showed that a high intake of coarse grain (OR 1.003; 95% CI 1.001–1.005, p < 0.01) and root and tuber crops (OR 1.003; 95% CI 1.001–1.004, p < 0.05) were independent risk factor for blaNDM carrier in health communities, suggesting a possible transfer of AMRbetweendietary andhumans. Surprisingly, we also showed an association between a higher intake of poultry as a protective, which may be explained by the beneficial effects on the gut microbiota. Conclusion: Dietary factors such as intake of coarse grain, root and tuber crops and poultry were associated with blaNDM carrier in health communities. The influence of dietary factorson blaNDM carrier in the present study provides insights for the tangible dietary advice with guidelines to the routine of people with the risk of blaNDM carrier. This demonstrates the role of dietary intake in the prevention of blaNDM carrier, since prevention is the best way to control modifiable risk factors. A lower carrier rate of blaNDM is helpful to reduce the possibility of transmission and pathogenicity. Further studies on food, microbiota and antimicrobial resistance are necessary to confirm this possible association and unravel underlying mechanisms.

scholarly journals PREVALENCE OF BOVINE FACIOLOSIS IN HALABA MUNICIPAL ABATTOR SOUTHERN ETHIOPIA

2016 ◽  
Vol 4 (11) ◽  
pp. 82-91
Author(s):  
Muna Abdella ◽  
WubitTafese Mhatebu
Keyword(s):  
Risk Factors ◽  
Body Condition ◽  
Cross Sectional Study ◽  
Control Measures ◽  
Southern Ethiopia ◽  
Multivariable Logistic Regression Analysis ◽  
Cross Sectional ◽  
Significant Difference ◽  
Prevention And Control Measures ◽  
Associated Risk Factors

A cross-sectional study was carried out from November 2015 to march 2016 on bovine fasciolosis, to assess the abattoir based prevalence, predominant species of bovine fasciolosis and associated risk factors of the disease in cattle slaughtered in Halaba municipal abattoir. A total of 384 cattle were examined using post mortem examination. Infection rates were (3.64%), 2.34%, 2.08%, and 1.82 % F. gigantic, F. hepatica, mixed and immature respectively with the overall prevalence of 9.88 % (38). F. gigantic was found to be the most prevalent species in cattle of the study area. Multivariable logistic regression analysis showed that the risk of fasciola infection was significantly higher in poor body condition animals than in medium and good body condition animals (p < 0.05). However, in terms of age, sex and breed, no statistically significant difference was found between infected animals (p > 0.05).The present study showed that bovine fasciolosis is one of the important pathogens in cattle in the study area and warrants appropriate disease prevention and control measures and further epidemiological investigations to determine the different agro ecological risk factors on the occurrence of the disease.

scholarly journals Seroprevalence and Risk Factors Associated with Contagious Caprine Pleuropneumonia in Western Amhara, Northwest Ethiopia

2019 ◽  
Vol 2019 ◽  
pp. 1-7
Author(s):  
Askale Abrhaley ◽  
Mebrat Ejo ◽  
Tsegaw Fentie
Keyword(s):  
Risk Factors ◽  
Cross Sectional Study ◽  
Northwest Ethiopia ◽  
Control Measures ◽  
Enzyme Linked Immunosorbent Assay ◽  
Multivariable Logistic Regression Analysis ◽  
High Seroprevalence ◽  
Cross Sectional ◽  
Contagious Caprine Pleuropneumonia ◽  
Associated Risk Factors

Contagious caprine pleuropneumonia (CCPP) has been identified as a significant problem in goat production, especially in the arid and semiarid lowland areas of Ethiopia. Even though CCPP was reported in most of the goat rearing areas of the country, there is no adequate information on the disease in the Amhara Region. Cross-sectional study was conducted from November 2016 to April 2017 in the districts of Western Amhara to estimate the seroprevalence and identify the associated risk factors for occurrence of the CCPP. The risk factors considered included age, sex, agroclimate, and districts. A competitive enzyme-linked immunosorbent assay (cELISA) was carried out on a total of 400 goat sera samples, out of which 34 samples were found seropositive for specific antibodies against CCPP, with the overall seroprevalence of 8.5% (95% confidence interval (CI) =5.8, 11.2). Among the epidemiological factors considered, age and sex of the goats were not significantly associated with CCPP seroprevalence (p>0.05). However, the seropositivity was slightly higher in adults (9.9%) and female goats (9.0%) compared to young (6.3%) and male (7.5%) goats, respectively. The analysis of seroprevalence by district shows that the seroprevalence of CCPP in Metema (OR=14.34; 95%CI= 1.80, 114.09; p=0.012) and Fogera (OR=9.99; 95%CI= 1.10, 91.16; p= 0.041) was significantly higher compared to other study districts. Multivariable logistic regression analysis also identified the district as a risk factor for the occurrence of a high seroprevalence of CCPP. The present study revealed the seroprevalence and the distribution of CCPP in Western Amhara districts, and hence appropriate control measures including regular investigation and vaccination should be implemented to alleviate the problem.

scholarly journals Exploring health literacy in Wuhan, China: a cross-sectional analysis

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Xin Mei ◽  
Qing Zhong ◽  
Gong Chen ◽  
Yuanxia Huang ◽  
Junlin Li
Keyword(s):  
Risk Factors ◽  
Health Literacy ◽  
Chronic Diseases ◽  
Urban Areas ◽  
Cross Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Logistic Regression Models ◽  
Education Levels ◽  
Chi Square Test

Abstract Background In recent years, research on health literacy has become increasingly focused on the health care system and public health. This cross-sectional study aimed to investigate health literacy and analyse the risk factors that affect health literacy in Wuhan, China. Methods Multistage stratified random sampling was used to select 5304 urban and rural residents aged 15 to 69 years from 204 monitoring points in 15 districts of Wuhan. Using the Chinese Citizen Health Literacy Questionnaire (HLQ) (2018 edition), a face-to-face survey was conducted from November to December 2018. Risk factors that may affect health literacy were assessed using the Chi-square test and multivariate logistic regression models. Results The knowledge rate of health literacy was relatively low (19.3%). The knowledge rate of health-related behaviour and lifestyle (BAL, 17.3%) was the lowest of the three aspects of health literacy, and the knowledge rate of chronic diseases (CD, 19.0%) was the lowest of the six dimensions of health literacy. Respondents who lived in urban areas, had higher education levels, worked as medical staff, had a higher household income and did not suffer from chronic diseases were likely to have higher health literacy. Conclusions The health literacy levels of citizens in Wuhan are insufficient and need to improve.

scholarly journals TB-diabetes comorbidity and associated factors in Maekel Zone, Eritrea: A cross sectional study.

2021 ◽  
Author(s):  
Zenawi Zeramariam Araia ◽  
Araia Berhane Mesfin ◽  
Amanuel Hadgu Mebrahtu ◽  
Adiam Ghebreyohanns Tewelde ◽  
Randa Osman ◽  
...  
Keyword(s):  
Risk Factors ◽  
Associated Factors ◽  
Fasting Blood Glucose ◽  
Scale Up ◽  
Cross Sectional Study ◽  
P Value ◽  
Multivariable Logistic Regression Analysis ◽  
Sectional Study ◽  
Cross Sectional ◽  
Independent Risk Factors

Abstract Background: Both diabetes mellitus (DM) and tuberculosis (TB) are among the leading causes of morbidity and mortality in Eritrea. TB-DM comorbidity is known to complicate TB care, control and prevention. However, systematically studied epidemiological data on TB-DM comorbidity and its associated risk factors is lacking in this country. Objective: This study aimed to assess the prevalence of DM and its associated factors among TB patients in Maekel region, Eritrea.Methods: Analytical cross-sectional study was conducted in eleven TB diagnostic and treatment sites. Pretested data extraction tool was used to collect data from medical records. Prevalence data was analysed using frequencies, proportions and median. To determine DM risk factors, univariable and multivariable logistic regression analysis was done with 95%CI and p value < 0.05 considered significant. Results: Out of total eligible (1,134) TB cases, DM prevalence was 9.88%. Age and BMI were identified as independent risk factors for DM among TB patients. Higher odds of DM was found among TB patients aged 45-54 (aOR: 4.85[1.39-16.94], p= 0.013) and those ≥ 55 (aOR: 6.99[2.12-23.04], p= 0.001). TB cases with normal BMI were two times more likely to have DM (aOR: 2.00[1.23-3.26], p= 0.005) compared to those underweight. Conclusion: The prevalence of DM among TB cases observed in this study is high, a clarion call to scale up current efforts to integrate TB-DM services within routine care. Furthermore, age and BMI were identified as independent risk factors for DM in TB cases, pointing to the need to pay attention to age and BMI status when managing this co-morbidityKey words: TB-DM prevalence, transient hyperglycaemia, fasting blood glucose, pre-diabetes, Eritrea.

scholarly journals Prevalence and risk factors for SARS-CoV-2 infection in children with and without symptoms seeking care in Managua, Nicaragua: results of a cross-sectional survey

BMJ Open ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. e051836
Author(s):  
Jorge A Huete-Pérez ◽  
Kacey C Ernst ◽  
Cristiana Cabezas-Robelo ◽  
Lucia Páiz-Medina ◽  
Sheyla Silva ◽  
...  
Keyword(s):  
Risk Factors ◽  
Clinical Symptoms ◽  
Age Distribution ◽  
Epidemiological Data ◽  
Cross Sectional Study ◽  
Comorbid Condition ◽  
Prevention Measures ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
High Prevalence

ObjectiveThis study aimed to capture key epidemiological data on SARS-CoV-2 infection in Nicaraguan children (≤18 years) seeking medical care, between 6 October and 16 November 2020.DesignIn this cross-sectional study, 418 children were recruited: 319 with symptoms characteristic of COVID-19 and 99 with no symptoms of illness. Children were tested for SARS-CoV-2 RNA using loop-mediated isothermal amplification. A questionnaire was employed to identify symptoms, risk factors, comorbidities and COVID-19 prevention measures.SettingResearch was carried out in four hospitals and two clinics in Managua, Nicaragua, where schools and businesses remained open throughout the COVID-19 pandemic.ParticipantsChildren were enrolled into a possible COVID-19 group if presenting with clinical symptoms. A comparison group included children lacking any COVID-19 symptoms attending routine check-ups or seeking care for issues unrelated to COVID-19.ResultsA high prevalence (43%) of SARS-CoV-2 infection was found, which was relatively equivalent in symptomatic and non-symptomatic children. Age distribution was similar between symptomatic and non-symptomatic children testing positive for SARS-CoV-2. Symptomatic children who tested positive for SARS-CoV-2 were 2.7 times more likely to have diarrhoea (26.7% in positive vs 12.0% in negative; OR=2.7 (95% CI 1.5 to 4.8), p=0.001) and were 2.0 times more likely to have myalgia (17.8% in positive vs 9.8% in negative; OR=2.0 (95% CI 1.0 to 3.8), p=0.04). Children with COVID-19 symptoms, who tested positive for SARS-CoV-2, were more likely to be under age 5 years and to have a pre-existing comorbid condition than children who tested positive but did not have symptoms.ConclusionsThis is the first paediatric study to provide laboratory-confirmed data on SARS-CoV-2 infection in Nicaragua, crucial for paediatric health services planning and a successful COVID-19 response. The high prevalence of the virus suggests widespread and sustained community transmission, underscoring the urgent need for robust data on the true extent of SARS-CoV-2 infection throughout Nicaragua.

Seroprevalence and risk factors of Toxoplasma gondii infection in humans in East Hararghe Zone, Ethiopia

2015 ◽  
Vol 144 (1) ◽  
pp. 64-71 ◽  
Author(s):  
B. TILAHUN ◽  
Y. HAILU ◽  
G. TILAHUN ◽  
H. ASHENAFI ◽  
M. VITALE ◽  
...  
Keyword(s):  
Risk Factors ◽  
Congenital Toxoplasmosis ◽  
Water Source ◽  
Cross Sectional Study ◽  
Multivariable Logistic Regression Analysis ◽  
Serum Samples ◽  
Recent Infection ◽  
Cross Sectional ◽  
The Status ◽  
Toxoplasma Gondii Infection

SUMMARYA cross-sectional study was conducted from April 2013 to September 2013 to determine the seroprevalence and possible risk factors for human Toxplasma gondii infection in East Hararghe Zone, Ethiopia. Serum samples were analysed using direct agglutination test, and immunosorbent agglutination assay for detecting IgG (n = 354) and IgM (n = 167) T. gondii antibodies. The T. gondii IgG and IgM seroprevalences were 65·8% [95% confidence interval (CI) 60·62–70·75] and 8·98% (95% CI 5·11–14·38), respectively. Gender difference in IgG seroprevalence was not significant (P > 0·05), but 69·5% of adults exhibited an IgG seroresponse to T. gondii. Pregnant women showed 76·4% and 9·3% seropositivity to IgG and IgM antibodies, respectively. Multivariable logistic regression analysis identified the risk factors significantly associated with T. gondii seropositivity were district [odds ratio (OR) 2·24, 95% CI 1·25–4·01, P = 0·007], pipe water source (OR 6·70, 95% CI 2·70–16·64, P < 0·001), age, with adults (OR 4·32, 95% CI 1·91–9·75, P < 0·001), and keeping cats in the home (OR 2·01, 95% CI 1·11–3·65, P = 0·021). The high seroprevalence of toxoplasmosis in the human population in the study area and the corresponding level of IgM seropositivity may be indicative of reactivation or recent infection and further studies on the status of congenital toxoplasmosis in the study area merit consideration.

scholarly journals Prevalence of bacterial vaginosis in Portuguese pregnant women and vaginal colonization byGardnerella vaginalis

PeerJ ◽  
2017 ◽  
Vol 5 ◽  
pp. e3750 ◽  
Author(s):  
Daniela Machado ◽  
Joana Castro ◽  
José Martinez-de-Oliveira ◽  
Cristina Nogueira-Silva ◽  
Nuno Cerca
Keyword(s):  
Risk Factors ◽  
Bacterial Vaginosis ◽  
Pregnant Women ◽  
Epidemiological Data ◽  
Cross Sectional Study ◽  
Public Hospitals ◽  
Gardnerella Vaginalis ◽  
Cross Sectional ◽  
Vaginal Colonization ◽  
Northwest Region

BackgroundWe aimed to determine the prevalence of vaginal colonization byGardnerella vaginalisand of bacterial vaginosis (BV) in Portuguese pregnant women, and to identify risk factors for BV andG. vaginaliscolonization in pregnancy.MethodsA cross-sectional study was conducted among pregnant women aged ≥ 18 years who were attending in two public hospitals of the Northwest region of Portugal. Epidemiological data was collected by anonymous questionnaire. BV was diagnosed by Nugent criteria andG. vaginalispresence was identified by polymerase chain reaction. Crude associations between the study variables and BV orG. vaginaliscolonization were quantified by odds ratios (ORs) and their 95% confidence intervals (CIs).ResultsThe prevalences of BV and ofG. vaginaliscolonization among Portuguese pregnant women were 3.88% and 67.48%, respectively. Previous preterm delivery and colonization byG. vaginaliswere factors with very high OR, but only statistically significant for a 90% CI. Conversely, higher rates ofG. vaginaliscolonization were found in women with basic educational level (OR = 2.77, 95% CI [1.33–5.78]), during the second trimester of pregnancy (OR = 6.12, 95% CI [1.80–20.85]) and with BV flora (OR = 8.73, 95% CI [0.50–153.60]).DiscussionDespite the lower number of women with BV, prevalence ratios and association with risk factors were similar to recent European studies. However, the percentage of healthy women colonized byG. vaginaliswas significantly higher than many previous studies, confirming thatG. vaginaliscolonization does not always lead to BV development.

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