QUANTITATIVE EXPERIMENTS UPON THE OCCURRENCE AND DISTRIBUTION OF VITAMIN A IN THE BODY, AND THE INFLUENCE OF THE FOOD

1925 ◽  
Vol 47 (6) ◽  
pp. 1646-1653 ◽  
Author(s):  
H. C. Sherman ◽  
L. C. Boynton
Keyword(s):  
Vitamin A ◽  
The Body

Research Recommendations for Applying Vitamin A-Labelled Isotope Dilution Techniques to Improve Human Vitamin A Nutrition

2014 ◽  
Vol 84 (Supplement 1) ◽  
pp. 52-59 ◽  
Author(s):  
Sherry A. Tanumihardjo ◽  
Anura V. Kurpad ◽  
Janet R. Hunt
Keyword(s):  
Public Health ◽  
Vitamin A ◽  
Vitamin A Deficiency ◽  
Human Subjects ◽  
The Body ◽  
Pool Size ◽  
Serum Retinol ◽  
Vitamin A Status ◽  
Status Assessment ◽  
Total Body

The current use of serum retinol concentrations as a measurement of subclinical vitamin A deficiency is unsatisfactory for many reasons. The best technique available for vitamin A status assessment in humans is the measurement of total body pool size. Pool size is measured by the administration of retinol labelled with stable isotopes of carbon or hydrogen that are safe for human subjects, with subsequent measurement of the dilution of the labelled retinol within the body pool. However, the isotope techniques are time-consuming, technically challenging, and relatively expensive. There is also a need to assess different types of tracers and doses, and to establish clear guidelines for the use and interpretation of this method in different populations. Field-friendly improvements are desirable to encourage the application of this technique in developing countries where the need is greatest for monitoring the risk of vitamin A deficiency, the effectiveness of public health interventions, and the potential of hypervitaminosis due to combined supplement and fortification programs. These techniques should be applied to validate other less technical methods of assessing vitamin A deficiency. Another area of public health relevance for this technique is to understand the bioconversion of β-carotene to vitamin A, and its relation to existing vitamin A status, for future dietary diversification programs.

Influence of zeolite and shungite on the content of vitamin A in the body of broiler chickens for mycotoxicosis

2020 ◽  
Vol 23 (12) ◽  
pp. 51-54
Author(s):  
S.A. Tanaseva ◽  
◽  
О.K. Ermolaeva ◽  
L.E. Matrosova ◽  
A.Z. Mukharlyamov ◽  
...  
Keyword(s):  
Vitamin A ◽  
Broiler Chickens ◽  
The Body

Review of Curd, Paneer and Cheese as Nitya Asevaniya Ahara Dravya w.s.r. to Dadhi, Kilat and Kurchika

2017 ◽  
Vol 2 (1) ◽  
Author(s):  
Saylee Deshmukh ◽  
Vyas M. K.
Keyword(s):  
Vitamin A ◽  
Growth And Development ◽  
Milk Protein ◽  
The Body ◽  
Rich Source ◽  
Food Items ◽  
Common Food ◽  
Daily Diet ◽  
Healthy Growth

Curd, Paneer and Cheese are rich source of milk protein, calcium, Vitamin A, Phosphorous, vitamins, minerals and protein which are required by the body in high proportions for healthy growth and development. It is common food in India. Cheese is also a rich source of fat. Curd, Paneer and Cheese can be correlated with Dadhi, Paneer and Cheese in Ayurveda classics which are listed in Nitya Asevaniya Ahara Dravya (food items not to be taken in daily diet). Present study aims to explain rationale behind description of these food items as Nitya Asevaniya Ahara Dravya.

CHYLOUS ASCITES IN INFANCY

PEDIATRICS ◽  
1951 ◽  
Vol 7 (5) ◽  
pp. 632-641
Author(s):  
DONALD GRIBETZ ◽  
ABRAM KANOF
Keyword(s):  
Vitamin A ◽  
Newborn Infant ◽  
General Circulation ◽  
Chylous Ascites ◽  
The Body ◽  
Fat Absorption ◽  
Aqueous Dispersions ◽  
Fat Soluble Vitamins ◽  
Supportive Management ◽  
Lymphatic Pathways

A description of a case of chylous ascites with chylocele unassociated with chylous fluid in any other of the body cavities is described. The literature is reviewed and a summary of four similar cases is presented. The 25 cases in the literature are analyzed in terms of etiology, association of chylocele, roentgenographic findings, treatment and prognosis. It is suggested that all such cases, particularly when they occur in the newborn infant, should be treated with conservative measures, i.e., paracentesis and supportive management, before resort to laparotomy. Studies concerning the absorption of vitamin A are presented which indicate that where defects in fat absorption through lymphatic pathways exist, the use of aqueous dispersions of fat soluble vitamins ensures their absorption into the general circulation.

scholarly journals Analysis of βeta-carotene from Jongi (Dillenia Serrata Thunb.) as a source of vitamin A

2021 ◽  
Vol 10 (2) ◽  
pp. 184-190
Author(s):  
Khairun Nisa ◽  
Ryka Marina Walanda
Keyword(s):  
Chronic Disease ◽  
Vitamin A ◽  
Essential Role ◽  
Antioxidant Activities ◽  
Beta Carotene ◽  
Neurological Function ◽  
The Body ◽  
Yellow Orange ◽  
Β Carotene ◽  
Healthy Eyes

Beta-carotene is converted in the body to vitamin A, a powerful antioxidant that plays an essential role in maintaining healthy eyes, skin, and neurological function. Beta-carotene and other carotenoids have antioxidant activities and are valued for their ability to prevent chronic disease. β-carotene is found in yellow, orange, red, and green fruits. The purpose of this study was to determine the β-carotene in Jongi. Jongi (Dillenia Serrata Thunb.) is an endemic fruit of Sulawesi which contains β-carotene. The samples used in this study were raw jongi and ripe jongi extracted with n-hexane: acetone (1:4). To the samples were analyzed quantitatively using UV-Vis spectrophotometry at a wavelength of 450.00 nm. The results showed that the β-carotene in raw jongi was 0.3554 mg/100 g and the β- carotene in ripe jongi was 1.1841 mg/100 g. Ripe jongi consist of more β-carotene than the raw jongi, hence better as a source of Vitamin A.

Specific features of fat-soluble vitamins in the indigenous and administrative population of the Far North

2021 ◽  
Vol 22 (3) ◽  
pp. 13-16
Author(s):  
V. I. Korchin ◽  
◽  
L. N. Bikbulatova ◽  
T. Ya. Korchina ◽  
◽  
...  
Keyword(s):  
Comparative Analysis ◽  
Vitamin A ◽  
The Body ◽  
Antioxidant Vitamins ◽  
Technogenic Pollution ◽  
Far North ◽  
Northern Territories ◽  
Harsh Climate ◽  
Fat Soluble Vitamins ◽  
Nenets Autonomous

In recent decades, interest in the study of the content of fat-soluble antioxidant vitamins among residents of the northern territories of Russia has not weakened, which is associated with the transformation of the diet in a harsh climate, a negative ecological situation resulting from the technogenic pollution of the biosphere with various toxicants, and urbanization of the environment. In recent decades, interest in the study of fat-soluble antioxidant vitamins among residents of the northern territories of Russia has not weakened, which is due to the transformation of the diet in a harsh climate, a negative environmental situation that arose as a result of technogenic pollution of the biosphere with various toxicants. Аim. Conduct a comparative analysis of the content vitamins A, D, E in indigenous and alien populations, living on the territory of the Yamalo-Nenets Autonomous Okrug. Material and methods. The study involved 185 males of working age (31.3 ± 12.2 years), permanently residing in the territory of the Yamalo-Nenets Autonomous Okrug. The study participants were divided into 2 groups: the control group (97 representatives of the newcomer population) and the main group (88 people from the ethnic population: Nenets, Khanty). In all examined individuals, vitamins A and E were determined in the blood by the fluorometric method, and the concentration of hydroxyvitamin D – 25 (OH) D3 was determined using the chemiluminescent method. Results. In the course of a comparative analysis of the content of the studied vitamins in the blood, it was found that the average values of vitamin A in the newcomer population were in the range of optimal values, while the provision with vitamins D and E was 1.4 and 1.1 times lower than the minimum. permissible physiological values, respectively. The opposite picture was observed in the aboriginal population, who had a pronounced deficiency of only vitamin A. Conclusion. The results obtained indicate the presence of intergroup features in the content of fat-soluble vitamins in the body of the population of the Far North, which requires a corresponding correction of the diet and the development of a set of preventive measures aimed at improving the ecology of the environment.

scholarly journals Loss of vitamin A in fortified edible oils and ghee during cooking in asian traditional style

2012 ◽  
Vol 47 (2) ◽  
pp. 243-248 ◽  
Author(s):  
Hifza Akhtar ◽  
Lubna Tahir ◽  
Shahid Mahmud ◽  
Shahnaz Hamid
Keyword(s):  
Vitamin A ◽  
Night Blindness ◽  
Edible Oils ◽  
Normal Growth ◽  
The Body ◽  
Regulatory Function ◽  
Deep Fat Frying ◽  
Cooking Oil ◽  
Balanced Diet ◽  
Cooking Oils

Vitamin 'A' is essential for normal growth and its deficiency causes night blindness, affects the regulatory function of skin and reduces the    general resistance of organism to infection. This deficiency does not occur by using balanced diet or by fortification of staple food with appropriate amount of Vitamin 'A'. In Pakistan vitamin 'A' fortification is done in vegetable ghee/cooking oil. It is generally assumed that  fortified amount of vitamin 'A' is fully destroyed when the food is cooked at high temperature. The present study was focused to examine the effect of Pakistani traditional cooking style on the degree of destruction of vitamin 'A' mandatory fortified in the vegetable ghee/ cooking oils. The study indicates that there are some losses of Vitamin A of the fortified oils during cooking. However in case of deep fat frying destruction of added vitamin 'A' is more pronounced. The loss of vitamin 'A' was less than 50%,  when the food was cooked in Pakistani style in case of all the cooking oils/ vegetable ghee. In prolonged frying conditions substantial amount of vitamin 'A' (45%) remains in the oil. Any how, this retention of vitamin 'A' is sufficient to meet the body requirements when oils/ghee was fortified according to the prescribed Pakistan Pure Food Rules 1965 i.e. 33,000 IU per Kg.   DOI: http://dx.doi.org/10.3329/bjsir.v47i2.11461   Bangladesh J. Sci. Ind. Res. 47(2), 243-248, 2012  

scholarly journals Bilateral Keratomalacia Secondary to Diet Induced Vitamin A Deficiency in an Ethiopian Young woman: A Case Report

1970 ◽  
Vol 29 (2) ◽  
Author(s):  
Kumale Tolesa Daba ◽  
Dagmawit Kifle ◽  
Jafer Kedir Ababora
Keyword(s):  
Vitamin A ◽  
Low Socioeconomic Status ◽  
Night Blindness ◽  
Early Recognition ◽  
Vitamin A Deficiency ◽  
The Body ◽  
Parotid Glands ◽  
Low Socioeconomic ◽  
Background Diet ◽  
University Department

BACKGROUND: Diet induced vitamin A deficiency is less commonly seen in otherwise healthy adults, due to large store of vitamin A in the body. Night blindness is the commonest manifestation of vitamin A deficiency in adults, whereas Keratomalacia is a rare manifestation.CASE REPORT: A 27 years old Ethiopian woman came to Jimma University Department of Ohthalmology with a compliant of protrusion of the globe content of both eyes within a week, after having redness and fear of light of both eyes for 2 months. She was a mother of twins and had low socioeconomic status. On general examination, she was cachectic with enlarged parotid glands. On ocular examination, she was bilaterally blind and had dry ocularsurface. There was bilaterally melted cornea with prolapsed uveal tissue. After several investigations she was diagnosed as bilateral Keratomalacia (stage X3B) secondary to diet induced vitamin A deficiency. She was supplemented with vitamin A and other nutritional supplementation. Topical lubricating drops and ointments were administered. Finally, conjunctival flap was done to preserve the globe.CONCLUSION: Although it is rare, treating physicians should be aware of the occurrence of Keratomalacia in adults which is potentially blinding. Early recognition and treatment of vitamin A deficiency at the stage of night blindness is essential in reducing blindness caused by Keratomalacia.

scholarly journals Multiple cytochrome P-450 genes are concomitantly regulated by vitamin A under steady-state conditions and by retinoic acid during hepatic first-pass metabolism

2011 ◽  
Vol 43 (1) ◽  
pp. 57-67 ◽  
Author(s):  
A. Catharine Ross ◽  
Christopher J. Cifelli ◽  
Reza Zolfaghari ◽  
Nan-qian Li
Keyword(s):  
Gene Expression ◽  
Retinoic Acid ◽  
Steady State ◽  
Vitamin A ◽  
Dynamic Range ◽  
Dynamic Change ◽  
The Body ◽  
Retinol Binding Protein ◽  
Dietary Vitamin ◽  
Wide Range

Vitamin A (retinol) is an essential precursor for the production of retinoic acid (RA), which in turn is a major regulator of gene expression, affecting cell differentiation throughout the body. Understanding how vitamin A nutritional status, as well as therapeutic retinoid treatment, regulates the expression of retinoid homeostatic genes is important for improvement of dietary recommendations and therapeutic strategies using retinoids. This study investigated genes central to processes of retinoid uptake and storage, release to plasma, and oxidation in the liver of rats under steady-state conditions after different exposures to dietary vitamin A (deficient, marginal, adequate, and supplemented) and acutely after administration of a therapeutic dose of all- trans-RA. Over a very wide range of dietary vitamin A, lecithin:retinol acyltransferase (LRAT) as well as multiple cytochrome P-450s (CYP26A1, CYP26B1, and CYP2C22) differed by diet and were highly correlated with one another and with vitamin A status assessed by liver retinol concentration (all correlations, P < 0.05). After acute treatment with RA, the same genes were rapidly and concomitantly induced, preceding retinoic acid receptor (RAR)β, a classical direct target of RA. CYP26A1 mRNA exhibited the greatest dynamic range (change of log 26 in 3 h). Moreover, CYP26A1 increased more rapidly in the liver of RA-primed rats than naive rats, evidenced by increased CYP26A1 gene expression and increased conversion of [3H]RA to polar metabolites. By in situ hybridization, CYP26A1 mRNA was strongly regulated within hepatocytes, closely resembling retinol-binding protein (RBP)4 in location. Overall, whether RA is produced endogenously from retinol or administered exogenously, changes in retinoid homeostatic gene expression simultaneously favor both retinol esterification and RA oxidation, with CYP26A1 exhibiting the greatest dynamic change.

Vitamin A plasma kinetics in northern fur seals (Callorhinus ursinus), using vitamin A2 as a tracer

1995 ◽  
Vol 73 (1) ◽  
pp. 10-14 ◽  
Author(s):  
Liza M. Mazzaro ◽  
J. Lawrence Dunn ◽  
Harold C. Furr ◽  
Richard M. Clark
Keyword(s):  
Vitamin A ◽  
The Body ◽  
Plasma Vitamin ◽  
Maximum Plasma ◽  
Callorhinus Ursinus ◽  
Base Line ◽  
Fish Diet ◽  
Plasma Kinetics ◽  
Fur Seals ◽  
Northern Fur Seals

Vitamin A2 (3,4-didehydroretinol), a natural analog of retinol, was used to determine the plasma kinetics of vitamin A in two northern fur seals (Callorhinus ursinus) receiving two levels of vitamin A supplements. After a single oral dose, the time required to reach maximum plasma vitamin A2 concentration for both subjects was approximately 2 h, which is much less than the 8–12 h observed with humans. The level of vitamin A supplementation did not affect base-line plasma retinol concentrations or plasma kinetics. The mean sojourn time, the average time spent by a molecule of vitamin A in the body before being lost, was 40 days for one animal and 73 days for the other. The daily vitamin A requirement estimated from the disposal rate was 0.32–0.64 μmol per day for the two animals. The presumed upper safe level was calculated at 1.3–6.4 μmol vitamin A per day. It would appear that the fish diet commonly provided to these animals can meet their vitamin A requirements. Supplementation may only be warranted to offset vitamin loss during storage and handling of the food. However, a conservative approach to supplementation should be used, as chronic vitamin A toxicity is a danger.

Sign in / Sign up

Export Citation Format

Share Document