Specific features of fat-soluble vitamins in the indigenous and administrative population of the Far North

2021 ◽  
Vol 22 (3) ◽  
pp. 13-16
Author(s):  
V. I. Korchin ◽  
◽  
L. N. Bikbulatova ◽  
T. Ya. Korchina ◽  
◽  
...  

In recent decades, interest in the study of the content of fat-soluble antioxidant vitamins among residents of the northern territories of Russia has not weakened, which is associated with the transformation of the diet in a harsh climate, a negative ecological situation resulting from the technogenic pollution of the biosphere with various toxicants, and urbanization of the environment. In recent decades, interest in the study of fat-soluble antioxidant vitamins among residents of the northern territories of Russia has not weakened, which is due to the transformation of the diet in a harsh climate, a negative environmental situation that arose as a result of technogenic pollution of the biosphere with various toxicants. Аim. Conduct a comparative analysis of the content vitamins A, D, E in indigenous and alien populations, living on the territory of the Yamalo-Nenets Autonomous Okrug. Material and methods. The study involved 185 males of working age (31.3 ± 12.2 years), permanently residing in the territory of the Yamalo-Nenets Autonomous Okrug. The study participants were divided into 2 groups: the control group (97 representatives of the newcomer population) and the main group (88 people from the ethnic population: Nenets, Khanty). In all examined individuals, vitamins A and E were determined in the blood by the fluorometric method, and the concentration of hydroxyvitamin D – 25 (OH) D3 was determined using the chemiluminescent method. Results. In the course of a comparative analysis of the content of the studied vitamins in the blood, it was found that the average values of vitamin A in the newcomer population were in the range of optimal values, while the provision with vitamins D and E was 1.4 and 1.1 times lower than the minimum. permissible physiological values, respectively. The opposite picture was observed in the aboriginal population, who had a pronounced deficiency of only vitamin A. Conclusion. The results obtained indicate the presence of intergroup features in the content of fat-soluble vitamins in the body of the population of the Far North, which requires a corresponding correction of the diet and the development of a set of preventive measures aimed at improving the ecology of the environment.

PEDIATRICS ◽  
1951 ◽  
Vol 7 (5) ◽  
pp. 632-641
Author(s):  
DONALD GRIBETZ ◽  
ABRAM KANOF

A description of a case of chylous ascites with chylocele unassociated with chylous fluid in any other of the body cavities is described. The literature is reviewed and a summary of four similar cases is presented. The 25 cases in the literature are analyzed in terms of etiology, association of chylocele, roentgenographic findings, treatment and prognosis. It is suggested that all such cases, particularly when they occur in the newborn infant, should be treated with conservative measures, i.e., paracentesis and supportive management, before resort to laparotomy. Studies concerning the absorption of vitamin A are presented which indicate that where defects in fat absorption through lymphatic pathways exist, the use of aqueous dispersions of fat soluble vitamins ensures their absorption into the general circulation.


2014 ◽  
Vol 84 (Supplement 1) ◽  
pp. 52-59 ◽  
Author(s):  
Sherry A. Tanumihardjo ◽  
Anura V. Kurpad ◽  
Janet R. Hunt

The current use of serum retinol concentrations as a measurement of subclinical vitamin A deficiency is unsatisfactory for many reasons. The best technique available for vitamin A status assessment in humans is the measurement of total body pool size. Pool size is measured by the administration of retinol labelled with stable isotopes of carbon or hydrogen that are safe for human subjects, with subsequent measurement of the dilution of the labelled retinol within the body pool. However, the isotope techniques are time-consuming, technically challenging, and relatively expensive. There is also a need to assess different types of tracers and doses, and to establish clear guidelines for the use and interpretation of this method in different populations. Field-friendly improvements are desirable to encourage the application of this technique in developing countries where the need is greatest for monitoring the risk of vitamin A deficiency, the effectiveness of public health interventions, and the potential of hypervitaminosis due to combined supplement and fortification programs. These techniques should be applied to validate other less technical methods of assessing vitamin A deficiency. Another area of public health relevance for this technique is to understand the bioconversion of β-carotene to vitamin A, and its relation to existing vitamin A status, for future dietary diversification programs.


2020 ◽  
Vol 23 (12) ◽  
pp. 51-54
Author(s):  
S.A. Tanaseva ◽  
◽  
О.K. Ermolaeva ◽  
L.E. Matrosova ◽  
A.Z. Mukharlyamov ◽  
...  
Keyword(s):  

2018 ◽  
Vol 74 (1) ◽  
pp. 6029-2018
Author(s):  
HANDAN MERT ◽  
SERKAN YİLDİRİM ◽  
IBRAHİM HAKKİ YORUK ◽  
KİVANC IRAK ◽  
BAHAT COMBA ◽  
...  

Vitamins are essential for the health of all living organisms. Vitamins E, A, D and K are known as fat-soluble vitamins, and deprivation of vitamin E causes various disorders, especially in the reproduction and cardiovascular systems and in muscle functions. Vitamin A, on the other hand, has roles in various biological functions – like eyesight – and the growth, reproduction and differentiation of epithelial cells. Vitamin A deficiency leads to the keratinization of the epithelium, and disorders related to the metaplasies of the genital and genitourinary systems. Conversely, vitamin D is defined as a pro-hormone and is responsible for Cahomeostasis, and thus indirectly affects the bone metabolism, bone structure, and cellular and neural functions of Ca. White muscle disease (WMD) can occur in newborn lambs, but is more commonly seen in lambs of up to 3 months of age. In this study, 30 lambs of 3 to 50-days-old from different flocks diagnosed with White Muscle Disease (WMD) were selected as research material, while the control group consisted of 8 healthy lambs. With the aim of clarifying the cause of WMD, serum fat-soluble vitamins, retinol, α-tocopherol and vitamin D3 levels were determined in 16 lambs. Gluteal and heart musclet issue samples also were taken from 30 lambs with WMD. The vitamin levels of the samples were analysed by HPLC. The levels of serum α-tocopherol, retinols, and vitamin D3 were foundto be low in the diseased animals, but only retinol (p<0.001) and α-tocopherol (p<0.0011) level differences were statistically relevant. Macroscopically, Zenker’s necrosis was determined in the heart muscles of 17 lambs, and in the gluteal and chest muscles of 6 lambs. 7 lambs displayed necrosis in both their heart and in gluteal muscles. The samples were analyzed microscopically to reach similar findings: swollen homogeneous pink muscles, pycnotic nuclei, and hyperaemic and haemorrhagic blood vessels in gluteal, chest and heart muscles. Hyaline degeneration and Zenker's necrosis, dystrophic regions in necrotic areas, cc was detected as a severe disease in lambs at an early stage of life with advanced degeneration in different muscle tissues. Deficiency of fat-soluble vitamins was also detected in the sick animals. Control group lambs had higher levels of α tocopherol and retinol (p<0.001) compared to the sick lambs. .


Author(s):  
Saylee Deshmukh ◽  
Vyas M. K.

Curd, Paneer and Cheese are rich source of milk protein, calcium, Vitamin A, Phosphorous, vitamins, minerals and protein which are required by the body in high proportions for healthy growth and development. It is common food in India. Cheese is also a rich source of fat. Curd, Paneer and Cheese can be correlated with Dadhi, Paneer and Cheese in Ayurveda classics which are listed in Nitya Asevaniya Ahara Dravya (food items not to be taken in daily diet). Present study aims to explain rationale behind description of these food items as Nitya Asevaniya Ahara Dravya.


Antioxidants ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 483
Author(s):  
Olaf Sommerburg ◽  
Susanne Hämmerling ◽  
S. Philipp Schneider ◽  
Jürgen Okun ◽  
Claus-Dieter Langhans ◽  
...  

Rationale: Cystic fibrosis (CF), caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, leads to impaired pancreatic function and therefore reduced intestinal absorption of lipids and fat-soluble vitamins especially in patients with CF developing pancreatic insufficiency (PI). Previous studies showed that CFTR modulator therapy with lumacaftor-ivacaftor (LUM/IVA) in Phe508del-homozygous patients with CF results in improvement of pulmonary disease and thriving. However, the effects of LUM/IVA on plasma concentration of the lipid soluble vitamins A and E remain unknown. Objectives: To investigate the course of plasma vitamin A and E in patients with CF under LUM/IVA therapy. Methods: Data from annual follow-up examinations of patients with CF were obtained to assess clinical outcomes including pulmonary function status, body mass index (BMI), and clinical chemistry as well as fat-soluble vitamins in Phe508del-homozygous CF patients before initiation and during LUM/IVA therapy. Results: Patients with CF receiving LUM/IVA improved substantially, including improvement in pulmonary inflammation, associated with a decrease in blood immunoglobulin G (IgG) from 9.4 to 8.2 g/L after two years (p < 0.001). During the same time, plasma vitamin A increased significantly from 1.2 to 1.6 µmol/L (p < 0.05), however, levels above the upper limit of normal were not detected in any of the patients. In contrast, plasma vitamin E as vitamin E/cholesterol ratio decreased moderately over the same time from 6.2 to 5.5 µmol/L (p < 0.01). Conclusions: CFTR modulator therapy with LUM/IVA alters concentrations of vitamins A and vitamin E in plasma. The increase of vitamin A must be monitored critically to avoid hypervitaminosis A in patients with CF.


Author(s):  
A.S. Rudenko ◽  
R.E. Dolgodvorov ◽  
S.A. Smirnov ◽  
A.P. Smirnov ◽  
A.N. Korkishko

Article gives a comparative analysis of using road clothes made of graded breakstone and gravelly sand mixes (GSM) for autonomous oil fields located in the northern territories of the Russian Federation. Positive and negative characteristics of inert material delivered to the field are noted. There have been made calculations based on regulatory acts for road clothes of transition type with following analysis of their cost. The technology of making GSM on objects is also described. This technology includes preparation of a mixture on a separate pad directly on construction object. The possibility of including sand located nearly the construction object into the mixture is analyzed. Major advantages of using GSM during construction of roads using practical experience are reviewed. The condition of the cover during the operation period is shown.


2021 ◽  
pp. 311-317
Author(s):  
N.M. Podgornova ◽  
A.R. Zainutdinova

The article reflects the importance of isotonic drinks to maintain optimal fluid balance and replace the loss of electrolytes in the body of athletes. Consumer preferences are studied, and a comparative analysis of some isotonic drinks is presented. It has been established that the majority of isotonic agents have artificial colors, preservatives, and high sucrose content, the excessive use of which leads to the formation of various kinds of diseases.


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