scholarly journals Respiratory function modulated during execution, observation, and imagination of walking via SII

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Antonello Pellicano ◽  
Gianluca Mingoia ◽  
Christoph Ritter ◽  
Giovanni Buccino ◽  
Ferdinand Binkofski

AbstractThe Mirror Neurons System (MNS) consists of brain areas active during actions execution, as well as observation-imagination of the same actions. MNS represents a potential mechanism by which we understand other's action goals. We investigated MNS activation for legs actions, and its interaction with the autonomic nervous system. We performed a physiological and fMRI investigation on the common neural structures recruited during the execution, observation, and imagination of walking, and their effects on respiratory activity. Bilateral SMA were activated by all three tasks, suggesting that these areas are responsible for the core of the MNS effect for walking. Moreover, we observed in bilateral parietal opercula (OP1, secondary somatosensory cortex-SII) evidence of an MNS subtending walking execution-observation-imagination that also modulated the respiratory function. We suggest that SII, in modulating the vegetative response during motor activity but also during observation-imagination, consists of a re-enacting function which facilitates the understanding of motor actions.

Author(s):  
Rakshith . ◽  
Shivakumar . ◽  
Sreeharsha . ◽  
Divyasree .

The core principles in Ayurveda give prime importance to Agni, Prakriti, Ahara (food) and Vihara (lifestyle) in maintaining health. Present era people are scheduled to one or the other works due to which they are following unrightful food and habits which lead the manifestation of one of the common disorder which troubles person a lot - Amlapitta. By excess “Hurry, Worry and Curry” GIT disorders are the most common, not only affecting physical health but also psychological and social health. Amlapitta is one of that and it is a burning problem of the whole World. Amalpitta is composed of word Amla and Pitta. Amlapitta is a very common disease caused by Vidagdha Pitta with features like Amlodgara, Tiktodgara, Hrit, Kantha Daha etc. Pathya recommended in Amlapitta are Yava, Godhuma, Purana Shali, Mudga Yusha, Lajasaktu etc. Apathya recommended in Amlapitta are Navanna, Avidugdha, Masha, Kulattha, Dadhi and etc. So this present review article throws light on Pathya (conducive) and Apathya (non conducive) in Amlapitta.


Author(s):  
William Demopoulos ◽  
Peter Clark

This article is organized around logicism's answers to the following questions: What is the basis for our knowledge of the infinity of the numbers? How is arithmetic applicable to reality? Why is reasoning by induction justified? Although there are, as is seen in this article, important differences, the common thread that runs through all three of the authors discussed in this article their opposition to the Kantian thesis that reflection on reasoning with mere concepts (i.e., without attention to intuitions formed a priori) can never succeed in providing satisfactory answers to these three questions. This description of the core of the view differs from more usual formulations which represent the opposition to Kant as an opposition to the contention that mathematics in general, and arithmetic in particular, are synthetic a priori rather than analytic.


2021 ◽  
pp. 174569162199063
Author(s):  
Cecilia Heyes ◽  
Caroline Catmur

Ten years ago, Perspectives in Psychological Science published the Mirror Neuron Forum, in which authors debated the role of mirror neurons in action understanding, speech, imitation, and autism and asked whether mirror neurons are acquired through visual-motor learning. Subsequent research on these themes has made significant advances, which should encourage further, more systematic research. For action understanding, multivoxel pattern analysis, patient studies, and brain stimulation suggest that mirror-neuron brain areas contribute to low-level processing of observed actions (e.g., distinguishing types of grip) but not to high-level action interpretation (e.g., inferring actors’ intentions). In the area of speech perception, although it remains unclear whether mirror neurons play a specific, causal role in speech perception, there is compelling evidence for the involvement of the motor system in the discrimination of speech in perceptually noisy conditions. For imitation, there is strong evidence from patient, brain-stimulation, and brain-imaging studies that mirror-neuron brain areas play a causal role in copying of body movement topography. In the area of autism, studies using behavioral and neurological measures have tried and failed to find evidence supporting the “broken-mirror theory” of autism. Furthermore, research on the origin of mirror neurons has confirmed the importance of domain-general visual-motor associative learning rather than canalized visual-motor learning, or motor learning alone.


Scanning ◽  
2017 ◽  
Vol 2017 ◽  
pp. 1-7
Author(s):  
Xu Chen ◽  
Tengfei Guo ◽  
Yubin Hou ◽  
Jing Zhang ◽  
Wenjie Meng ◽  
...  

A new scan-head structure for the scanning tunneling microscope (STM) is proposed, featuring high scan precision and rigidity. The core structure consists of a piezoelectric tube scanner of quadrant type (for XY scans) coaxially housed in a piezoelectric tube with single inner and outer electrodes (for Z scan). They are fixed at one end (called common end). A hollow tantalum shaft is coaxially housed in the XY-scan tube and they are mutually fixed at both ends. When the XY scanner scans, its free end will bring the shaft to scan and the tip which is coaxially inserted in the shaft at the common end will scan a smaller area if the tip protrudes short enough from the common end. The decoupled XY and Z scans are desired for less image distortion and the mechanically reduced scan range has the superiority of reducing the impact of the background electronic noise on the scanner and enhancing the tip positioning precision. High quality atomic resolution images are also shown.


Author(s):  
I. A. Shapoval ◽  

The paper presents the interdisciplinary analysis of the determinants of the system of self-communication discourse and internal dialogue as the forms of objectivation of human mental content focused on some actions for meeting some objectives. The author describes discourse as integration of communication and language processes in self-understanding and personal identity. Contextually determined and dynamic self-communication discourse, as a way of acquirement of new senses and confirmation of old ones, verbalizes current personal values. The study results reveal the characteristics and relations of the internal dialogue discourse determinants within the human objectivity–subjectivity continuum. Discourse determinants prescribe its context and rules and include the prototype place and agents with their motives and objectives. Self-positions manifested in Self and Non-Self (Other Self) binary self-predications form the core pair of agents. The modality of a person’s attitude to own Self-positions makes their communications a dialogue or a monologue on the boundary of their sub-territories as a discourse prototype place. The degree of discourse agency, its closeness within the prototype place, or transgression openness depends on the complexity and differentiation of Self-concept and ego boundaries functionality. The frustration of meta-necessity to keep self-confidence and self-acceptance by reassessment and reformation of interrelations of Self-positions determines the motives and objectives of self-communication. The common goal of self-organization is implemented through the internal dialogue in the form of institutionalization, verification, and integration of their Self-predications. Status-role characteristics of agents and functionality of discourse prototype place determine the specificity of its motives and objectives according to the systemic effects of Self-organization.


Author(s):  
Vittorio Gallese ◽  
Corrado Sinigaglia

Mental simulation was claimed to provide a distinctive way of gaining knowledge about others’ actions and thoughts since the late 1980s. A decade later, the discovery of mirror neurons in macaque monkeys and the evidence of mirror brain areas in humans presented a new angle on this claim, suggesting also an embodied approach to simulation. The aim of the present chapter is to introduce and discuss this embodied approach and its role in basic social cognition. In doing this, we shall start by characterizing the distinctive features of embodied simulation (ES), especially in relation to its its motor aspects. Then, we shall provide evidence for the claim that ES may be critically involved in understanding others’ actions. Finally, we shall explore the conjecture that ES might involve a common ground for action execution and observation not only at the functional but also at the phenomenological level.


Author(s):  
Ruihui Han

Guanxi circle play a critical role in ancient China politics. Based on guanxi, two kinds of guanxi groups formed: formal guanxi circle and informal guanxi circle. The former refers to the group centered the emperor; the latter refers to the groups with the powerful and charismatic figures as the core, except for the emperor. In order to consolidate the political power, the emperors in different periods would try to prevent the informal guanxi circle in political structure. Besides, various scriptures also denounce the informal guanxi circle, deeming such circle as harmful. The judgement of informal guanxi circle appeals to research, as there is no previous researcher has address such problems. This study set out to examine whether the informal guanxi circle is harmful to the whole political structure. Results show that the informal guanxi circle, in the antecedent of satisfactory communication, can be extremely meaningful to the whole political structure. This study implies that the fact of informal guanxi circle is on the contrary of the common sense derived from the scriptures and the superficial ancient political activities, such as the emperor’s order to prevent the informal guanxi circle. The findings can contribute a better understanding of the ancient informal guanxi circle in ancient political structure in China.


2021 ◽  
Author(s):  
Xi Cen ◽  
Yan Wang ◽  
LeiLei Zhang ◽  
XiaoXiao Xue ◽  
Yan Wang ◽  
...  

Abstract BackgroundType 2 diabetes mellitus (T2DM) is regarded as Pi Dan disease in traditional Chinese medicine (TCM). Dahuang Huanglian Xiexin Decoction (DHXD), a classical TCM formula, has been used for treating Pi Dan disease in clinic, its pharmacological mechanism has not been elucidated. MethodsThis study used network pharmacological analysis and molecular docking approach to explore the mechanism of DHXD on T2DM. Firstly, the compounds in DHXD were obtained from TCMSP and TCMID databases, the potential targets were determined based on TCMSP and UniProt databases. Next, Genecards, Digenet and UniProt databases were used to identify the targets of T2DM. Then, the protein-protein interaction (PPI) network was established with overlapping genes of T2DM and compounds, and the core targets in the network were identified and analyzed. Then, the David database was used for GO and KEGG enrichment analysis. Finally, the target genes were selected and the molecular docking was completed by Autodock software to observe the binding level of active components with target genes.ResultsA total of 397 related components and 128 overlapping genes were identified. After enrichment analysis, it was found that HIF-1, TNF, IL-17 and other signaling pathways, as well as DNA transcription, gene expression, apoptosis and other cellular biological processes had the strongest correlation with the treatment of T2DM by DHXD, and most of them occurred in the extracellular space, plasma membrane and other places, which were related to enzyme binding and protein binding. In addition, 42 core genes of DHXD, such as VEGFA, TP53 and MAPK1, were considered as potential therapeutic targets, indicating the potential mechanism of DHXD on T2DM. Finally, the results of molecular docking showed that HIF-1 pathway had strong correlation with the target genes INSR and GLUT4, quercetin and berberine had the strongest binding power with them respectively.ConclusionThis study summarized the main components of DHXD in the treatment of T2DM, identified the core genes and pathways, and systematically analyzed the interaction of related targets, trying to lay the foundation for clarifying the potential mechanism of DHXD on T2DM, so as to carry out further research in the future.


Author(s):  
Levette S. Dames ◽  
Jennifer Barrow

Recently the Council for the Accreditation of Counseling and Related Educational Program (CACREP) broad granted many graduate counselor education programs eight or more year accreditation. In order for these institutions to have been awarded its accreditation, eight core counseling areas should have been addressed in their program or university alike. For counselor education programs to enter the 21st century, technology and media devices should be embraced in all of the eight core counseling areas. The chapter examines the usefulness and effectiveness of enhanced-technology and media devices of five of the eight core counseling areas for advancement and improvement of effective skills for counselors-in-training (CIT). University web-base and audio/video media devices were the common enhanced-technology devices used among five of the core counseling areas. In addition, the school counseling program technologies were also examined. Finally, implications for counselor education are provided.


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