scholarly journals Assessment of the relationship of serum liver enzymes activity with general and abdominal obesity in an urban Bangladeshi population

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Nurshad Ali ◽  
Abu Hasan Sumon ◽  
Khandaker Atkia Fariha ◽  
Md Asaduzzaman ◽  
Rahanuma Raihanu Kathak ◽  
...  
Keyword(s):  
General Population ◽  
Abdominal Obesity ◽  
Liver Enzymes ◽  
Serum Levels ◽  
General Obesity ◽  
Enzymes Activity ◽  
Elevated Liver Enzymes ◽  
Bangladeshi Population ◽  
Relationship Of ◽  
The Relationship

AbstractObesity is a global health concern because of its increasing trend both in developed and developing countries. A limited number of studies have evaluated the association of liver enzymes with both general and abdominal obesity in the general population; data for the Bangladeshi population are not available yet. This study aimed to assess the relationship of serum liver enzymes activity with both general and abdominal obesity in Bangladeshi adults. In total, 540 blood samples were obtained from the participants (388 males and 152 females) and analyzed for serum levels of ALT, AST, GGT, and ALP using standard methods. General obesity was defined as body mass index (BMI) ≥ 27.5 kg/m2 and abdominal obesity was defined as waist circumference (WC) ≥ 90 cm in males and ≥ 80 cm in females. The relationship between liver enzymes and obesity was evaluated by multivariate logistic regression models. Overall, 58% of participants in the general obesity group and 55% of the participants in the abdominal obesity group had at least one or more elevated levels of liver enzymes. The prevalence of elevated liver enzymes was significantly higher in the obesity group compared to the normal BMI and WC groups (p < 0.05 for all cases). The mean level of serum ALT, AST and GGT were significantly higher in the obesity group than the normal BMI group (p < 0.05). In the WC groups, mean AST and GGT were significantly higher in the obesity group compared to the normal group (p < 0.05). In regression analysis, serum levels of ALT showed an independent and significant association with general obesity, whereas, serum GGT showed a significant association with both general and abdominal obesity. In conclusion, a high prevalence of elevated liver enzymes was observed among participants included in the present study. Of the four enzymes, serum GGT was independently associated with both general and abdominal obesity. Further studies are required to understand the complex relationship between liver enzymes and obesity in the general population.

scholarly journals Assessment of the relationship between serum uric acid levels and liver enzymes activity in Bangladeshi adults

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Noyan Hossain Molla ◽  
Rahanuma Raihanu Kathak ◽  
Abu Hasan Sumon ◽  
Zitu Barman ◽  
Ananya Dutta Mou ◽  
...  
Keyword(s):  
Uric Acid ◽  
General Population ◽  
Serum Uric Acid ◽  
Liver Enzymes ◽  
Multinomial Logistic Regression ◽  
Adult Population ◽  
Enzymes Activity ◽  
Significant Difference ◽  
The Mean ◽  
The Relationship

AbstractSerum uric acid (SUA) level has been suggested to be associated with cardiovascular disease, diabetes and metabolic syndrome. However, little is known about the relationship between SUA and liver enzymes activity in the general population. The present study aimed to assess the relationship between SUA and serum liver enzymes in an adult population in Bangladesh. In this cross-sectional study, a total of 410 blood samples were collected from apparently healthy adults aged > 18 years. SUA, liver enzymes, lipid profile and other biochemical markers were measured in the collected samples by using standard methods. Multinomial logistic regression model was used to assess the relationship between SUA and elevated levels of liver enzymes among the participants. Overall, the prevalence of hyperuricemia was 30.1% with 32.2% in male and 18.6% in female participants. About 33% of the participants had at least one or more elevated levels of liver enzymes. The mean level of SUA was significantly higher in males (389.3 ± 96.9 µmol/L) than in the female (290.4 ± 89.8 µmol/L) subjects (p < 0.001). There was a significant difference in the mean levels of serum ALT and GGT between the male (34.5 ± 16.0 U/L and 26.7 ± 19.5 U/L, respectively) and female (25.0 ± 13.0 U/L and 19.5 ± 13.2 U/L, respectively) participants (p < 0.001 and p < 0.01, respectively). An increasing trend was observed in the mean levels of serum ALT and GGT across the SUA quartile groups (p < 0.001 and p < 0.01, respectively). SUA showed a positive and significant correlation with serum ALT (p < 0.001) and GGT (p < 0.01). In further statistical analysis after adjustment for potential confounders, SUA showed an independent and significant association with serum ALT and GGT in all regression models. In conclusion, SUA was strongly associated with serum levels of ALT and GGT after adjustment for potential confounders. More prospective studies are needed to clarify the complex relationship between SUA and liver enzymes in the general population.

scholarly journals Relationship of Sodium Intake with Overweight/Obesity among Chinese Children and Adolescents: Data from the CNNHS 2010–2012

2021 ◽  
Vol 18 (9) ◽  
pp. 4551
Author(s):  
Kehong Fang ◽  
Yuna He ◽  
Yuehui Fang ◽  
Yiyao Lian
Keyword(s):  
Children And Adolescents ◽  
Abdominal Obesity ◽  
Sodium Intake ◽  
Saturated Fatty Acids ◽  
Positive Association ◽  
Chinese Children ◽  
Weighing Method ◽  
Relationship Of ◽  
The Relationship ◽  
Chinese Children And Adolescents

This study aims to examine association between sodium intake and overweight/obesity among Chinese children and adolescents. Data were obtained from China National Nutrition and Health Surveillance (CNNHS), 2010–2012. All participants recruited in this study aged 7–18 years old and provided complete dietary data on three-day consecutive 24 h dietary recalls combining with the household weighing method. Body Mass Index (BMI) was used to define overweight/obesity, and waist-to-height ratio (WHtR) was used to define abdominal obesity. Sodium intake showed association with risk of overweight/obesity assessed by BMI in the highest tertile group with OR of 1.48 (95%CI 1.13–1.94) and 1.89 (95%CI 1.33–2.67) for WHtR. After adjusted for gender, age, household income, area, energy, carbohydrates, protein, fat, saturated fatty acids, and fiber intake, the relationship between sodium intake and overweight/obesity and abdominal obesity are not changed. The same results were founded in subjects aged 10–18 years old. Our results reveal a positive association between sodium intake and overweight/obesity in Chinese children and adolescents, independent of energy consumption.

How matrix metalloproteinase (MMP)-9 (rs3918242) polymorphism affects MMP-9 serum concentration and associates with autism spectrum disorders: A case-control study in Iranian population

2021 ◽  
pp. 1-7
Author(s):  
Javid Rezaei Lord ◽  
Farhad Mashayekhi ◽  
Zivar Salehi
Keyword(s):  
Serum Concentration ◽  
Matrix Metalloproteinase ◽  
Serum Levels ◽  
Autism Spectrum ◽  
Enzyme Linked Immunosorbent Assay ◽  
Mmp9 Expression ◽  
Relationship Of ◽  
The Relationship ◽  
Metalloproteinase 9 ◽  
Control Study

Abstract The aim of this project was to evaluate the relationship of matrix metalloproteinase-9 (MMP-9) genetic variation and its serum concentration with autism spectrum disorder (ASD). One hundred ASD and 120 controls were enrolled in this study. Genomic DNA was extracted from blood and MMP-9 polymorphism was determined by polymerase chain reaction restriction fragment length polymorphism and serum levels were measured by enzyme-linked immunosorbent assay. The frequencies of CC, CT, and TT genotypes were 72%, 26%, and 2% in controls and 31%, 57%, and 12% in ASD, respectively. The frequencies of C and T alleles in ASD were 59.5% and 40.5%, and controls were 86% and 14%, respectively. There is a significant increase in serum MMP-9 levels in ASD as compared to controls. We have also shown that TT genotype is significantly associated with increase serum MMP-9 levels in patients (TT, CT, and CC serum levels were 91.77 ± 10.53, 70.66 ± 7.21, and 38.66 ± 5.52 and in controls were 55.55 ± 11.39, 42.66 ± 7.85, and 30.55 ± 6.34 ng/ml, respectively). It is concluded that there is a significant association between rs3918242 MMP-9 polymorphism and its serum concentration with autism. We also suggest that TT genotype is associated with increased MMP9 expression and may be a risk factor for ASD.

scholarly journals Association of Beverage Consumption with Obesity in Healthy Adults

2017 ◽  
Vol 1 (1) ◽  
pp. 37
Author(s):  
Sirine Maher Zahran
Keyword(s):  
Abdominal Obesity ◽  
Weight Status ◽  
Intervention Group ◽  
Overweight And Obesity ◽  
Abu Dhabi ◽  
Major Health ◽  
Sweetened Beverages ◽  
The One ◽  
Relationship Of ◽  
The Relationship

Background: The increased consumption of sugar-sweetened beverages (SSBs) has been found to be an important contributor of calories in the diet. Whether there is an association between the increased consumption of SSBs and the high rates of overweight and obesity is still questionable. The objective of this study was to examine the relationship of weight status and beverages consumed of adults in a residential compound in Abu Dhabi.Methods: Forty nine out of 65 residents form Al Reef Villas in Abu Dhabi agreed to participate in the study. Initial assessments including beverages frequency questionnaire and anthropometry measurements were completed for all participants. Participants who were identified as high beverages consumers were invited to a one-month intervention aiming to limit their beverages consumption. A final assessment was completed for all high consumers of beverages at the end of the one-month intervention.Results: 55% of the subjects were overweight or obese, and 51% had abdominal obesity. 73% consumed 100% fruit juices with no added sugar, 65% consumed soft drinks, and 60 % consumed plain milk and milk products. The majority (69%) consumed tea beverages rather than coffee beverages. There was no association between weight & beverages consumption. The mean energy percentage from beverages was 14.2 (± 11.1) among all participants. 53% were considered high consumers of beverages and 47% (n=23) were considered low consumers of beverages. The one-month intervention showed a significant decrease in % of calories from beverages and weight in the overweight & obese intervention group (p<0.001 and p<0.05) respectively.Conclusion: This study highlighted major health problems in Abu Dhabi including high rates of overweight, obesity, and abdominal obesity. The one-month intervention was effective in reducing the energy percentage from beverages and weight of the overweight and obese participants, but no association was found in this sample between beverages consumption and overweight and obesity.

The Newcomers Group

2018 ◽  
Author(s):  
Sarah-Neel Smith
Keyword(s):  
General Population ◽  
State Policy ◽  
Fine Arts ◽  
Press Coverage ◽  
Western Modernity ◽  
National Body ◽  
Relationship Of ◽  
The Village ◽  
The Relationship ◽  
Village Institutes

The Newcomers Group [YenilerGrubu] was formed in 1940 while its members were still students at the Istanbul Academy of Fine Arts under Leopold Levy (1840–1904), and was active through 1952. It is also known as the Harbor Group [LimanGrubu], in reference to the theme of the collective’s first exhibition, which featured scenes of waterfront life in Istanbul. Similar to art collective D Group (1933–1947), the Newcomers aimed to portray what they saw as uniquely Turkish social realities using formal strategies associated with Western modernity, including impressionist, fauvist, and cubist painting techniques. At the same time, the Newcomers claimed with greater urgency than the D Group that local artists were obligated to engage directly with Turkey’s general population. This preoccupation with the relationship of the artist in an elite social position to the larger national body was closely linked to ongoing debates both in state policy (reflected in the development of the Homeland Tours program from 1938–1943, and the Village Institutes from 1940–1954) and in the Turkish literary world. As a result, the Newcomers received ample press coverage and the support of major literary figures such as Hilmi Ziya Ülken (1901–1974) and Ahmet Hamdi Tanpınar (1901–1962), who also sought to develop national art forms rooted in Turkish popular experience.

scholarly journals Clinical and laboratory observations on serum folate-binding protein

Blood ◽  
1975 ◽  
Vol 46 (4) ◽  
pp. 599-609 ◽  
Author(s):  
ER Eichner ◽  
CJ Paine ◽  
VL Dickson ◽  
MD Jr Hargrove
Keyword(s):  
Binding Protein ◽  
Elevated Serum ◽  
Normal Subjects ◽  
Serum Levels ◽  
Serum Folate ◽  
Folate Level ◽  
Folate Binding Protein ◽  
Serum Folate Level ◽  
Relationship Of ◽  
The Relationship

Abstract We studied the effect of serum folate-binding protein (FBP) on folate radioassays and the relationship of the serum level of unsaturated FBP to the serum folate level in various clinical states. Our modification of a heat-extracted radioassay was compared to a whole serum radioassay. Our results confirmed the existence of elevated serum levels of unsaturated FBP in some normal subjects, in some women taking oral contraceptives, and in most patients with uremia. Elevated levels of unsaturated FBP will produce falsely low results in folate radioassay unless the FBP has been destroyed by heat, as was done in the modified radioassay here presented. In normal and uremic subjects, serum folate and unsaturated FBP levels tended to correlate, whereas in patients taking large doses of folic acid the level of unsaturated FBP fell as the level of serum folate rose.

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