scholarly journals The obesity epidemic and our gut microbiome – could it all be down to our ‘bugs’?

2017 ◽  
Vol 39 (2) ◽  
pp. 26-29 ◽  
Author(s):  
Douglas Rees

According to the World Health Organization, obesity is officially a global epidemic they have aptly termed – ‘Globesity’. Obesity worldwide has more than doubled since 1980, reaching 600 million in 2014, occurring in parallel with increased high-energy, low-nutrition food consumption and sedentary lifestyles – both of which result in a positive energy imbalance. These environmental factors influence our metabolism, by modifying the way our genes are expressed, and similarly those of any organisms within us, such as the 38 trillion bacterial microbes inhabiting our gastrointestinal tract (gut microbiome), compared with 30 trillion human cells in the entire body.

2021 ◽  
pp. 19-23
Author(s):  
Donizete Tavares Da Silva ◽  
Priscila De Sousa Barros Lima ◽  
Renato Sampaio Mello Neto ◽  
Gustavo Magalhães Valente ◽  
Débora Dias Cabral ◽  
...  

In March 2020, the World Health Organization (1) declared COVID-19 as a pandemic and a threat to global public health (2). The virus mainly affects the lungs and can cause acute respiratory distress syndrome (ARDS). In addition, coronavirus 2 severe acute respiratory syndrome (SARSCOV2) also has devastating effects on other important organs, including the circulatory system, brain, gastrointestinal tract, kidneys and liver


Author(s):  
Jaewon J. Lee ◽  
Scott Kopetz ◽  
Eduardo Vilar ◽  
John Paul Shen ◽  
Ken Chen ◽  
...  

COVID-19, the disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has rapidly spread throughout the world and was declared a pandemic by the World Health Organization, thus leading to a rapid surge in the efforts to understand the mechanisms of transmission, methods of prevention, and potential therapies. While COVID-19 frequently manifests as a respiratory infection,1 there is evidence for infection of the gastrointestinal (GI) tract1–4 with documented viral RNA shedding in the stool of infected patients.2,4 In this study, we aimed to investigate the expression of ACE2 and TMPRSS2, which are required for SARS-CoV-2 entry into mammalian cells,5 from single-cell RNA sequencing (scRNA-seq) datasets of five different parts of the GI tract: esophagus, stomach, pancreas, small intestine, and colon/rectum.


2021 ◽  
Vol 6 (12) ◽  
pp. 46-55
Author(s):  
Derya GERESİNLİ ◽  
Asiye AKYOL

The COVID-19 epidemic, which the World Health Organization regards as a "pandemic", continues to be perceived as a threat to survive for many people living in different parts of the world. The virus is a global epidemic; It affects everyone's lives negatively regardless of religion, language, race, gender, socioeconomic and sociocultural differences. Facing with a threat that develops suddenly, changes daily habits and can result in death is not a common situation for people, and the perception of threat and uncertainty it creates makes it difficult to cope with the situation. Uncertainty is an important part of the illness experience, and our response to uncertainty can significantly affect our illness outcomes. Mishel's Uncertainty Theory in Illness helps to find meaning in uncertainty again and to develop healthy coping mechanisms. The role of nurses in the management of uncertainty regarding illness; to facilitate the process and to adapt the patient to healthy reactions. In this case report; Within the scope of the Uncertainty in Illness Theory of Mishel, a 39-year-old nurse who was diagnosed with Covid 19 was planned to find a meaning in the disease again by planning the care process. It was stated that the theory can be applied in the acute illness as well as in the chronic illness.


Author(s):  
Majidreza M. Kazempour

Obesity is now replacing undernutrition and infectious diseases as the leading cause of ill health. It is considered as one of the greatest medical challenges to health in the United States; over 65% of American adults are either overweight or obese leading to 320,000 deaths each year in the United States (Kopelman, 2005). The annual medical costs of obesity in the United States are enormous (Bhattacharya and Bundorf, 2009). Globally, according to the World Health Organization, there are more than one billion overweight adults, of which at least 300 million are clinically obese. A recent National Health and Nutrition Examination Survey (NHANES) data (2003–2006) has showed that for children aged 6–11 years and 12–19 years, the prevalence of overweight was 17.0% and 17.6%, respectively.


Elements ◽  
2010 ◽  
Vol 6 (1) ◽  
Author(s):  
Kitsy Smith

As China's coffers have swelled over the past three decades, its citizens' waistlines have also expanded. Western goods and lifestyles habits are consistently being imported into the Asian giant, including the obesity epidemic. Chinese children are particularly susceptible and future generations face tremendous health risks despite medical advances. States and international bodies such as the World Health Organization are alarmed at the damage obesity is already producing. The price tag to treat the health problems associated with obesity and the rsulting loss in economic productivity is staggering. While this essay uses China as a case study to examine the causes of obesity and its consequences, social and economic health, the grim reality is that this pattern is occurring worldwide as countries develop and their people adopt Western "nutritional" norms.


Author(s):  
A. I. Novak ◽  
Y. O. Lyashchuk

The results of the development of a curd functional product with vegetable filler Melissa officinalis L. are presented. An analysis of the health status of the population carried out in recent years by the World Health Organization shows that the world community is facing acute questions related to the need to prevent the so-called “diseases of civilization”, which include diseases of the cardiovascular system, oncology, diseases associated with impaired lipid metabolism and the gastrointestinal tract, al ergii, decreased immunity, disorders of the nervous system. According to experts, many of these diseases leading to death, disability or disability have a steady upward trend. Up to 44% of the population of our country suffer from cardiovascular diseases (as of December 2019), while more than 82% have functional disorders leading to them. Malignant neoplasms and precancerous conditions are observed in 39% of the adult population, diseases of the gastrointestinal tract are found in more than 48% of the working population of the country. The solution to these problems may be the development of functional food products.


2022 ◽  
pp. 38-54
Author(s):  
Moulay Abdelmonaim El Hidan ◽  
Mohamed Rhazi ◽  
Mohamed Merzouki ◽  
Mustapha Agnaou ◽  
Moulay Abdeljalil Ait Baamrane ◽  
...  

The World Health Organization (WHO) recognized the coronavirus disease (COVID-19) as a worldwide pandemic caused by a newly discovered coronavirus responsible for Severe Acute Respiratory Syndrome (SARS-Cov2). The virus appeared in Wuhan, China in December 2019 and spread throughout the world, causing several mortality cases particularly in older people and those with chronic diseases. A body of evidence suggests a multi-target of SARS-Cov2, which may act beyond the respiratory system being responsible for other pathological complications, including the gastrointestinal tract, nervous, and the renal functions. The chapter will provide a literature review of the recent data on COVID-19 physiopathology involving in addition to the respiratory dysfunction all the potential physiological functions which could be independently and directly impaired by the SARS-Cov2.


2017 ◽  
Vol 24 (3) ◽  
Author(s):  
Olha Bobrykovych

Obesity has become one of the most urgent social problems worldwide. Continuous and rapid increase in obesity rates is considered by the World Health Organization as a global epidemic. Obesity affects children as well; the World Health Organization recognized childhood obesity as an acute public health crisis. Childhood obesity is often accompanied by arterial hypertension, hyperlipidemia and disorders of        carbohydrate metabolism resulting in symptom complex – metabolic syndrome. While teaching the problems of metabolic syndrome in children to interns, a significant attention is paid to risk factors, diagnosis, treatment and prevention of syndrome. Such approach will allow future pediatricians to diagnose and prevent the development of early complications of metabolic syndrome in children timely.


2021 ◽  
Vol 17 (2) ◽  
pp. 176-182
Author(s):  
Nawres Aref ◽  
Hussain Kareem

Novel Coronavirus (Covid-2019), which first appeared in December 2019 in the Chinese city of Wuhan. It is spreading rapidly in most parts of the world and becoming a global epidemic. It is devastating, affecting public health, daily life, and the global economy. According to the statistics of the World Health Organization on August 11, the number of cases of coronavirus (Covid-2019) reached nearly 17 million, and the number of infections globally distributed among most European countries and most countries of the Asian continent, and the number of deaths from the Coronavirus reached 700 thousand people around the world. . It is necessary to detect positive cases as soon as possible in order to prevent the spread of this epidemic and quickly treat infected patients. In this paper, the current literature on the methods used to detect Covid is presented. In these studies, the research that used different techniques of artificial intelligence to detect COVID-19 was reviewed as the coevolutionary neural network (ResNet50, ResNet101, ResNet152, InceptionV3, and Inception-ResNetV2) were proposed for the identification of patients infected with coronavirus pneumonia using chest X-ray radiographs By using 5-fold cross validation, three separate binary classifications of four grades (COVID-19, normal (healthy), viral pneumonia and bacterial pneumonia) were introduced. It has been shown that the pre-trained ResNet50 model offers the highest classification performance (96.1 percent accuracy for Dataset-1, 99.5 percent accuracy for Dataset-2, and 99.7 percent accuracy for Dataset-2) based on the performance results obtained.


Zoonoses ◽  
2021 ◽  
Vol 1 (1) ◽  
Author(s):  
Si Qin ◽  
Mengnan Cui ◽  
Siqi Sun ◽  
Jiyang Zhou ◽  
Zongmin Du ◽  
...  

As the novel coronavirus SARS-CoV-2 spread around the world, multiple waves of variants emerged, thus leading to local or global population shifts during the pandemic. A new variant named Omicron (PANGO lineage B.1.1.529), which was first discovered in southern Africa, has recently been proposed by the World Health Organization to be a Variant of Concern. This variant carries an unusually large number of mutations, particularly on the spike protein and receptor binding domain, in contrast to other known major variants. Some mutation sites are associated with enhanced viral transmission, infectivity, and pathogenicity, thus enabling the virus to evade the immune protective barrier. Given that the emergence of the Omicron variant was accompanied by a sharp increase in infection cases in South Africa, the variant has the potential to trigger a new global epidemic peak. Therefore, continual attention and a rapid response are required to decrease the possible risks to public health.


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