The methodological bases of construction of information system of diagnostics of technical condition of constructions of buildings and constructions and substantiation of efficiency of technologies of instrumental definition of parameters of buildings, constructions at all stages of their life cycle which are considered from a position of strategic information management are offered; carried out, from the standpoint of a systematic approach, the formalization of the processes of wear of building structures, which allows the creation of an effective and reliable analytical apparatus for monitoring the technical condition and diagnosis of future conditions in the process of their reliable and safe operation; built, using the apparatus of fuzzy sets, models and methods of monitoring a certain technical condition of buildings; The information technology of the decision support system, which is based on powerful intellectualizing analytical tools that allow experts to make more plausible assessments and management decisions, has been further developed. Based on the results of studying scientific sources, conclusions were made about the absence or need to deepen the solutions to the following problems: establishing general principles for the formation of a system for diagnosing the technical condition of buildings at all stages of their life cycle; lack of methodology to substantiate the effectiveness of technologies and tools for instrumental determination of parameters of buildings, structures and building areas at all stages of the life cycle; adaptation of methods for determining organizational and technological indicators to calculate the effectiveness of measurement systems and technology of their application; determining the impact of organizational and technical indicators on the efficiency of measurement systems and technology of their application; determination of the duration and periodicity of instrumental inspections as part of the operating costs of measuring systems; establishment of necessary volumes of instrumental observations at operation of buildings and constructions of substantiation of expenses of time for performance of measuring works at all stages of a life cycle of construction objects; lack of a single methodology for creating an automated system for diagnosing the technical condition of buildings; lack of integrated models and methods of modeling diagnostic processes that would ensure the effective functioning of information technology diagnostics of technical condition of buildings and high accuracy of expert decisions on their condition and forecasting the main technical characteristics of their operation under external and internal environments; the lack of a single information database that would make it possible to compare the results of surveys, to observe the dynamics of aging of buildings, to systematize conclusions about their condition.