scholarly journals Optimization of berth length of LNG terminal

2021 ◽  
Vol 248 ◽  
pp. 03009
Author(s):  
Yuchen Wang
Keyword(s):  
Oil And Gas ◽  
High Efficiency ◽  
Optimization Method ◽  
Research Progress ◽  
Comparison Analysis ◽  
Transport Mode ◽  
Multimodal Transport ◽  
Change Trend ◽  
Length Optimization

Based on the multimodal transport mode of LNG container, it is suitable for transportation, storage and land, and it can realize safe, high efficiency and convenient transportation, and meet the needs of modern LNG transportation. This paper discusses the change trend of LNG terminal berth length which has been built in recent years. The research progress of berth length optimization method of LNG terminal in China is described. The comparison analysis is made with the berth length optimization method of open oil and gas terminal, and some suggestions are put forward.

Metabolism and Distribution of Novel Tumor Targeting Drugs In Vivo

2020 ◽  
Vol 21 (13) ◽  
pp. 996-1008
Author(s):  
Mengli Wang ◽  
Qiuzheng Du ◽  
Lihua Zuo ◽  
Peng Xue ◽  
Chao Lan ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Small Molecule ◽  
High Efficiency ◽  
Tumor Therapy ◽  
Research Progress ◽  
Future Research ◽  
Pharmacokinetic Parameters ◽  
Molecular Characteristics ◽  
Targeted Drugs

Background: As a new tumor therapy, targeted therapy is becoming a hot topic due to its high efficiency and low toxicity. Drug effects of targeted tumor drugs are closely related to pharmacokinetics, so it is important to understand their distribution and metabolism in vivo. Methods: A systematic review of the literature on the metabolism and distribution of targeted drugs over the past 20 years was conducted, and the pharmacokinetic parameters of approved targeted drugs were summarized in combination with the FDA's drug instructions. Targeting drugs are divided into two categories: small molecule inhibitors and monoclonal antibodies. Novel targeting drugs and their mechanisms of action, which have been developed in recent years, are summarized. The distribution and metabolic processes of each drug in the human body are reviewed. Results: In this review, we found that the distribution and metabolism of small molecule kinase inhibitors (TKI) and monoclonal antibodies (mAb) showed different characteristics based on the differences of action mechanism and molecular characteristics. TKI absorbed rapidly (Tmax ≈ 1-4 h) and distributed in large amounts (Vd > 100 L). It was mainly oxidized and reduced by cytochrome P450 CYP3A4. However, due to the large molecular diameter, mAb was distributed to tissues slowly, and the volume of distribution was usually very low (Vd < 10 L). It was mainly hydrolyzed and metabolized into peptides and amino acids by protease hydrolysis. In addition, some of the latest drugs are still in clinical trials, and the in vivo process still needs further study. Conclusion: According to the summary of the research progress of the existing targeting drugs, it is found that they have high specificity, but there are still deficiencies in drug resistance and safety. Therefore, the development of safer and more effective targeted drugs is the future research direction. Meanwhile, this study also provides a theoretical basis for clinical accurate drug delivery.

scholarly journals Research on the Operating Characteristics of Hydraulic Free-Piston Engines: A Systematic Review and Meta-Analysis

Energies ◽  
2021 ◽  
Vol 14 (12) ◽  
pp. 3530
Author(s):  
Fukang Ma ◽  
Shuanlu Zhang ◽  
Zhenfeng Zhao ◽  
Yifang Wang
Keyword(s):  
Systematic Review ◽  
High Efficiency ◽  
Meta Analysis ◽  
Combustion Process ◽  
Research Progress ◽  
Future Research ◽  
Operating Characteristics ◽  
Piston Engine ◽  
Free Piston ◽  
Free Piston Engine

The hydraulic free-piston engine (HFPE) is a kind of hybrid-powered machine which combines the reciprocating piston-type internal combustion engine and the plunger pump as a whole. In recent years, the HFPE has been investigated by a number of research groups worldwide due to its potential advantages of high efficiency, energy savings, reduced emissions and multi-fuel operation. Therefore, our study aimed to assess the operating characteristics, core questions and research progress of HFPEs via a systematic review and meta-analysis. We included operational control, starting characteristics, misfire characteristics, in-cylinder working processes and operating stability. We conducted the literature search using electronic databases. The research on HFPEs has mainly concentrated on four kinds of free-piston engine, according to piston arrangement form: single piston, dual pistons, opposed pistons and four-cylinder complex configuration. HFPE research in China is mainly conducted in Zhejiang University, Tianjin University, Jilin University and the Beijing Institute of Technology. In addition, in China, research has mainly focused on the in-cylinder combustion process while a piston is free by considering in-cylinder combustion machinery and piston dynamics. Regarding future research, it is very important that we solve the instabilities brought about by chance fluctuations in the combustion process, which will involve the hydraulic system’s efficiency, the cyclical variation, the method of predicting instability and the recovery after instability.

scholarly journals A Review of Hydrogen Purification Technologies for Fuel Cell Vehicles

Catalysts ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 393
Author(s):  
Zhemin Du ◽  
Congmin Liu ◽  
Junxiang Zhai ◽  
Xiuying Guo ◽  
Yalin Xiong ◽  
...  
Keyword(s):  
Fuel Cells ◽  
Fuel Cell ◽  
Carbon Emission ◽  
High Efficiency ◽  
Impurity Content ◽  
Fuel Cell Vehicle ◽  
Research Progress ◽  
Hydrogen Purification ◽  
Fuel Cell Vehicles ◽  
Low Carbon

Nowadays, we face a series of global challenges, including the growing depletion of fossil energy, environmental pollution, and global warming. The replacement of coal, petroleum, and natural gas by secondary energy resources is vital for sustainable development. Hydrogen (H2) energy is considered the ultimate energy in the 21st century because of its diverse sources, cleanliness, low carbon emission, flexibility, and high efficiency. H2 fuel cell vehicles are commonly the end-point application of H2 energy. Owing to their zero carbon emission, they are gradually replacing traditional vehicles powered by fossil fuel. As the H2 fuel cell vehicle industry rapidly develops, H2 fuel supply, especially H2 quality, attracts increasing attention. Compared with H2 for industrial use, the H2 purity requirements for fuel cells are not high. Still, the impurity content is strictly controlled since even a low amount of some impurities may irreversibly damage fuel cells’ performance and running life. This paper reviews different versions of current standards concerning H2 for fuel cell vehicles in China and abroad. Furthermore, we analyze the causes and developing trends for the changes in these standards in detail. On the other hand, according to characteristics of H2 for fuel cell vehicles, standard H2 purification technologies, such as pressure swing adsorption (PSA), membrane separation and metal hydride separation, were analyzed, and the latest research progress was reviewed.

scholarly journals Research progress of viscoelastic surfactants for enhanced oil recovery

2021 ◽  
pp. 014459872098020
Author(s):  
Ruizhi Hu ◽  
Shanfa Tang ◽  
Musa Mpelwa ◽  
Zhaowen Jiang ◽  
Shuyun Feng
Keyword(s):  
Enhanced Oil Recovery ◽  
Oil Recovery ◽  
High Efficiency ◽  
Research Progress ◽  
Surfactant Flooding ◽  
Sweep Efficiency ◽  
The World ◽  
Washing Efficiency ◽  
Viscoelastic Surfactants ◽  
Viscoelastic Surfactant

Although new energy has been widely used in our lives, oil is still one of the main energy sources in the world. After the application of traditional oil recovery methods, there are still a large number of oil layers that have not been exploited, and there is still a need to further increase oil recovery to meet the urgent need for oil in the world economic development. Chemically enhanced oil recovery (CEOR) is considered to be a kind of effective enhanced oil recovery technology, which has achieved good results in the field, but these technologies cannot simultaneously effectively improve oil sweep efficiency, oil washing efficiency, good injectability, and reservoir environment adaptability. Viscoelastic surfactants (VES) have unique micelle structure and aggregation behavior, high efficiency in reducing the interfacial tension of oil and water, and the most important and unique viscoelasticity, etc., which has attracted the attention of academics and field experts and introduced into the technical research of enhanced oil recovery. In this paper, the mechanism and research status of viscoelastic surfactant flooding are discussed in detail and focused, and the results of viscoelastic surfactant flooding experiments under different conditions are summarized. Finally, the problems to be solved by viscoelastic surfactant flooding are introduced, and the countermeasures to solve the problems are put forward. This overview presents extensive information about viscoelastic surfactant flooding used for EOR, and is intended to help researchers and professionals in this field understand the current situation.

Well Placement Technique and Production Optimization for Mature Field - A Case Study of L-X Field

2020 ◽  
Vol 46 ◽  
pp. 168-179
Author(s):  
Patrick Nwafor ◽  
Kelani Bello
Keyword(s):  
Oil And Gas ◽  
Optimization Technique ◽  
Optimal Solution ◽  
Oil And Gas Industry ◽  
Optimization Method ◽  
Simulation Software ◽  
Production Optimization ◽  
Direct Optimization ◽  
Well Placement ◽  
Local Optimal Solution

A Well placement is a well-known technique in the oil and gas industry for production optimization and are generally classified into local and global methods. The use of simulation software often deployed under the direct optimization technique called global method. The production optimization of L-X field which is at primary recovery stage having five producing wells was the focus of this work. The attempt was to optimize L-X field using a well placement technique.The local methods are generally very efficient and require only a few forward simulations but can get stuck in a local optimal solution. The global methods avoid this problem but require many forward simulations. With the availability of simulator software, such problem can be reduced thus using the direct optimization method. After optimization an increase in recovery factor of over 20% was achieved. The results provided an improvement when compared with other existing methods from the literatures.

scholarly journals Optimal design of high efficiency double helical gear based on dynamics model

2021 ◽  
Vol 3 (8) ◽  
Author(s):  
Fengxia Lu ◽  
Xuechen Cao ◽  
Weiping Liu
Keyword(s):  
Dynamic Model ◽  
High Efficiency ◽  
Bending Strength ◽  
Sliding Friction ◽  
Elastohydrodynamic Lubrication ◽  
Optimization Method ◽  
Transmission Efficiency ◽  
Helical Gear ◽  
Transmission System ◽  
Vibration Displacement

AbstractA 16-degree-of-freedom dynamic model for the load contact analysis of a double helical gear considering sliding friction is established. The dynamic equation is solved by the Runge–Kutta method to obtain the vibration displacement. The method combines the friction coefficient model based on the elastohydrodynamic lubrication theory with the dynamic model, which provides a theoretical basis for the calculation of the power loss of the transmission system. Moreover, the sensitivity analysis of the parameters that affect the transmission efficiency is carried out, and an optimization method of meshing efficiency is proposed without reducing the bending strength of the gears. This method can directly guide the design of the double helical gear transmission system.

scholarly journals The use of the method of controlling the electrochemical parameters of aqueous solutions to combat complications in the operation of oil field pipelines

2021 ◽  
Vol 225 ◽  
pp. 01008
Author(s):  
Oleg Latypov ◽  
Sergey Cherepashkin ◽  
Dina Latypova
Keyword(s):  
Aqueous Solutions ◽  
Oil And Gas ◽  
High Efficiency ◽  
Oil Field ◽  
Oil Fields ◽  
Control Methods ◽  
Test Results ◽  
Chemical Reagents ◽  
Electrochemical Parameters ◽  
Very High

Corrosion of equipment in the oil and gas complex is a global problem, as it contributes to huge material costs and global disasters that violate the environment. Corrosion control methods used to protect equipment do not always ensure the absolute safety of the operation of oil and gas facilities. Moreover, they are quite expensive. The developed method for controlling the electrochemical parameters of aqueous solutions to combat complications during the operation of oil-field pipelines provides the necessary protection against corrosion. The method is economical and environmentally friendly, since it does not require the use of chemical reagents. The test results have shown a very high efficiency in dealing with complications in oil fields.

scholarly journals Overview of Polymers for Improved Oil Recovery Treatments

2020 ◽  
Author(s):  
Mohamed Saeed Shamlooh1 ◽  
Ahmed Hamza ◽  
Ibnelwaleed Hussein ◽  
Mustafa Nasser ◽  
Saeed Salehi
Keyword(s):  
Oil Recovery ◽  
Oil And Gas ◽  
High Efficiency ◽  
High Water ◽  
High Permeability ◽  
Chemical Methods ◽  
Improved Oil Recovery ◽  
Profile Modification ◽  
Fractured Carbonate ◽  
Deep Profile

High water production in oil and gas wells reduces significantly the recovery factor. Mechanical as well as chemical methods are applied to shut off water productive zones. Crosslinked polymers showed high efficiency to seal off water zones in high permeability sandstone and fractured carbonate reservoirs. Moreover, emulsified polymeric formulations have been introduced for deep profile modification by changing the wettability of the rock and hence allowing selective plugging of water. This poster provides an overview of the polymeric formulations used for such application.

scholarly journals Research on Key Technology of Electrochemical Sterilization and Physical Application for Circulating Cooling Water

2021 ◽  
Vol 2083 (2) ◽  
pp. 022068
Author(s):  
Xiaohui Wang ◽  
Chunyan Song ◽  
Xueying Xie ◽  
Nan Zhang ◽  
Ruiqing Guo ◽  
...  
Keyword(s):  
Electric Fields ◽  
Electrode Materials ◽  
High Efficiency ◽  
Thermal Power ◽  
Cooling Water ◽  
Environmentally Friendly ◽  
Research Progress ◽  
Electrode Spacing ◽  
Experimental Conditions ◽  
Circulating Cooling Water

Abstract As a high-efficiency, low-cost, convenient and environmentally friendly sterilization technology, electrochemical disinfection has developed rapidly in recent years. Electrochemical sterilization is an environmentally friendly sterilization technology. The research progress of this technology in the recent 30 years in sterilization mechanism and electrode materials is summarized. The mechanism of electrochemical sterilization includes the chemical effects of active chlorine, active intermediates, copper or silver ions, and the physical effects of electric fields; the electrode materials used are titanium anode, carbon cathode, and anode. The article combined with electrochemical equipment in a thermal power plant cold open circulating cooling water treatment experiment. Experimental research found that under the conditions of current density of 120A/m2, residence time of 10s, and electrode spacing of 1.8cm, the bactericidal effect can reach 97%. Under certain experimental conditions and a certain period of time, the total number of heterogeneous bacteria in the circulating cooling water after treatment can be effectively inhibited.

scholarly journals The Mesozoic of the South Caspian oil and gas province, Southwestern Turkmenistan – prospects for gas and oil exploration

2021 ◽  
pp. 102-133
Author(s):  
V.N. Melikhov ◽  
N.A. Krylov ◽  
I.V. Shevchenko ◽  
V.L. Shuster
Keyword(s):  
Oil And Gas ◽  
High Efficiency ◽  
State Of The Art ◽  
Oil Field ◽  
Seismic Exploration ◽  
Oil Exploration ◽  
The South ◽  
Analytical Review ◽  
Drilling Operations ◽  
Low Efficiency

Regarding the South Caspian oil and gas province, it is concluded that the Pliocene productivity prevails in the western part of the province, and that the gas and oil prospects of the eastern land side in the Mesozoic are prioritized. A retrospective analytical review of geological and geophysical data and publications on the Mesozoic of Southwestern Turkmenistan was carried out, which showed the low efficiency of the performed seismic and drilling operations in the exploration and evaluation of very complex Mesozoic objects. A massive resumption of state-of-the-art seismic exploration and appraisal drilling in priority areas and facilities performed by leading Russian companies is proposed. For some areas, a new, increased estimate of the projected gas resources is given. An example of modern high-efficiency additional exploration of the East Cheleken, a small Pliocene gas and oil field, which turned this field into a large one in terms of reserves, is given.

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