scholarly journals Use of Ovostim-CT in the prevention of hepatosis and retention of placenta in cows after calving

2021 ◽  
Vol 282 ◽  
pp. 03014
Author(s):  
P.V. Burkov

High milk productivity of cows after calving is the cause of liver damage in the form of hepatosis and premature retirement of animals. In such cases, a pathological examination simultaneously reveals violations in the form of protein and fatty degenerations with the subsequent destruction of cells, as well as disturbed circulation in the liver. Also, hepatoses can cause such postpartum complications in cows as retention of placenta. For the prevention of hepatosis, the drug “Ovostim-ct” is proposed, which contains cytotoxic sera against the tissues of the liver, ovary, spleen and muscle. In order to prevent liver damage and postpartum retention of placenta, the drug is used 1-1.5 months before calving at a dose of 1 ml per 100 kg of live weight subcutaneously or intramuscularly. The use of the hepatoprotector allowed to reduce the number of cases of hepatosis and retention of placenta in cows after calving. Also, “Ovostim-ct” had a favorable effect on the biochemical parameters of the blood serum of cows: there was an increase in the concentration of total protein by 6.7%, albumin - by 15.6% and glucose - by 45.8% in the blood.

Author(s):  
V. І. Khalak ◽  
O. S. Grabovska

The results of studies of the fattening and meat qualities of young pigs of large white breed of foreign origin, some biochemical parameters of blood serum and the results of calculating their correlation relationships are presented, and the economic efficiency of the research results is calculated. It was found that the biochemical parameters of blood serum in animals of the experimental group correspond to the physiological norm of clinically healthy animals, and their coefficient of variation ranges from 7.71 to 33.67 %. According to the main indicators of fattening and meat qualities (the age of reaching live weight of 100 kg, days, the thickness of the fat at the level of 6– 7 thoracic vertebrae, mm, the length of the chilled carcass, cm) corresponds to the “elite” class, and an effective assessment method sows and boars-producers by genotype is the use of a comprehensive index of feeding and meat qualities (B. Tyler index). The maximum indicators “average daily gain in live weight for the period of control fattening, kg”, “the length of the chilled carcass, cm”, “the length of the bacon half of the chilled carcass, cm” and the minimum values “age to reach live weight of 100 kg, days” and “bacon thickness the level of 6–7 thoracic vertebrae, mm ”is characterized by animals in which the comprehensive index of feeding and meat qualities (B. Tyler index) ranges from 160.14 to 174.04 points. Reliable correlation was established between the following pairs of signs: fat thickness at the level of 6–7 thoracic vertebrae, mm × total protein content, g / l (r=+ 0.375, tr=2.14), length of chilled carcass, cm × concentration of total lipoproteins , mg% (r=–0.622, tr=4.20), length of chilled carcass, cm × urea content, mmol/l (r=–0.445, tr=4.20), length of bacon half of chilled carcass, cm × content total protein, g / l (r=–0.533, tr=3.33), fat thickness at the level of 6–7 thoracic vertebrae, mm × concentration of total lipoproteins, mg% (r=–0.652, tr=4.55) the average daily gain in live weight for the period of control feeding, kg × concentration of total lipoproteins, mg% (r=+0.492, tr=2.99). The above indicates the prospect of using some biochemical indicators of blood serum for early prediction of fattening and meat qualities. It was established that the maximum increase in production in terms of "average daily gain in live weight during the period of control fattening, g" (4.87 %) was obtained from animals in which the B. Tyler index ranged from 160.14 to 174.04 points.


Author(s):  
N. Chornenka ◽  
Ya. Rayetska ◽  
O. Savchuk ◽  
L. Ostapchenko

During modeling of esophageal alkali burns 1 and 2 degrees in immature rats were observed violations of various metabolic systems, melanin administration helped to normalize the biochemical parameters. It was shown that under the esophageal burns there occurred violations of protein (total protein, albumin), nitrogen metabolism (creatinine, urea) metabolism of carbohydrate (glucose) and lipids (cholesterol), changed the activity of enzymes (GOT, GPT, CC), violated fluid and electrolyte balance (K +, Na +, Cl-, Ca2 +, Mg2 +, phosphates), while the introduction of melanin contributed to the normalization of these indicators. The most effective dose were of 0.5 mg/ kg and 1 mg/kg. There were found anti-toxic properties of melanin, which may be a promising drug for the normalization of metabolism in patients with burns of esophagus and prevent its complications.


PLoS ONE ◽  
2021 ◽  
Vol 16 (9) ◽  
pp. e0256661
Author(s):  
Fatima Dikhanbayeva ◽  
Elmira Zhaxybayeva ◽  
Zhuldyz Smailova ◽  
Arman Issimov ◽  
Zhechko Dimitrov ◽  
...  

This study aimed to assess potential feeding effect of camel milk curd mass and its mixes to experimental rat’s blood serum biochemical parameters, enzymatic activity and the peptide toxicity. Fifty healthy male Sprague-Dawley rats were divided into five groups (n = 10 each). Each group was fed with camel milk pure curd mass and its mixes for 16 days. At the end of the experiment, rats were sacrificed to collect the samples from the blood serum. Blood serum biochemical parameters total protein, cholesterol, glucose, albumin, triglycerides; the enzymatic activities of alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase were determined on the A25 automatic analyser, and peptide toxicity analysed by the reference method. The statistical data have shown no significant differences in body weight gain in all groups. Total protein decreased in group II, IV, and V; however, it increased in group III compared to the control group. Cholesterol grew up in group II and it slightly increased in group V, dropped in groups III and IV compared to group I result. Glucose increased in groups II, III, IV compared to group I; still, group V results show a slight decrease. Albumin decreased in group IV, yet in group V it increased than the group I result. Simultaneously, groups II and III results were changed with less percentage. Triglyceride grew up in groups II, V, and it dropped significantly in groups III, IV compared to the control group. De Ritis ratio of enzymes in groups II, III, and IV fluctuated between 1.31 and 0.98 IU/L; however, group V demonstrated significant data versus group I. Diets peptide toxicity in all groups was lower than control group data. The experimental results indicated that curd mass from camel milk could be used as a pure or with additives and it did not discover the observed side effects.


2021 ◽  
Vol 23 (101) ◽  
pp. 21-25
Author(s):  
L. V. Koreyba

The success of the control of obstetric diseases in cattle depends on the timely implementation of preventive measures, and, in cases of pathology, on diagnosis, effective obstetric care and treatment. A prominent place is given to blood tests among the methods that allow to objectively assess the state of health and the course of the pathological process in animals' bodies. The study of biochemical parameters of blood allows for the assessment of the state of metabolic processes in animals, with high accuracy in establishing the body's general condition and predicting complications and adjusting their prevention and therapy. The goal of the work: our work aimed to study the biochemical parameters of the blood of deep-calving heifers for the prediction, correction, and prevention of obstetric pathology during childbirth and puerperium. The research was carried out on deep-calving heifers of Holstein breed selected on the principle of analogues. Biochemical examination of blood serum was performed in the district laboratory of veterinary medicine. Indicators of protein and mineral metabolism were determined in the blood serum of deep- calving heifers: total protein, carotene, reserve alkalinity, inorganic phosphorus, albumin content, class M immunoglobulins. The obtained research results indicate that the total protein content corresponds to the norm in deep-calving heifers of the Holstein black-spotted breed. The protein coefficient exceeds the standard. There are pronounced deviations in the blood's biochemical parameters: low levels of carotene almost two-fold, reserve alkalinity – 1.91-fold, the total calcium content – by 16.08 % and the ratio of calcium to phosphorus by 17.78 %. Since the decrease in carotene content correlates with the predisposition to endometritis, the Holstein black-spotted breed's deep-calving heifers are prone to developing birth and postpartum pathology. For pregnant cows which are predisposed to postpartum obstetric pathology, that occur in weak parturition activity, failure to release the placenta, uterus subinvolution, endometritis and postpartum hypocalcaemia, unfavorable prognostication is the low concentration in blood plasma of general calcium, inorganic phosphorus and carotene.


Author(s):  
R. Milushev ◽  
V. Epifanov

Simmental breed of cattle combines dairy and beef productivity. The crossbreeding cows of Simmental breed with Red-and-White Holstein breed of cattle was supposed to obtain animals with high milk productivity, good adaptability to the industrial technology of milk productivity. Red-and-White breed of cows has been bred in Russia as a result of this crossbreeding. It is a relatively young breed of dairy productivity in our country. In order to evaluate the effect of crossbreeding and study the adaptive capabilities obtained by animals, the synthesis of alkaline phosphatase by its activity in blood serum has been studied. The level of activity of the enzyme reflected the intensity and direction of biochemical processes in animals, affecting the state of homeostasis in purebred (Simmental) and crossbred (F1 Simmental×Red-and-White Holstein) heifers and first-calf heifers. It has been found that activity of serum alkaline phosphatase has decreased with age in both purebred and crossbred animals. Crossbreds F1 surpassed purebred heifers in enzyme activity at 1 and 10 months of age, this difference was significant. The activity of the enzyme in first-calf heifers was different from that in the blood of growing heifers, they had it lower. A close and significant correlation has been found between the live weight of growing crossbred heifers and the activity of alkaline phosphatase in the blood serum at 2-, 6- and 12-month age. Crossbred first-calf heifers were significantly higher in milk yield for 90 days of lactation than their Simmental herdmates. The set of data on the activity of alkaline phosphatase in the blood of heifers and lactating cows is of both theoretical and practical value for zootechnical and biological sciences, revealing the regularities of the heterosis effect, deepening knowledge about the age-related biochemistry of crossbred animals and the formation of productive traits.


Author(s):  
Віктор Халак

The results of studies of fattening and meat qualities of young pigs of large white breed, some biochemical parameters of blood serum (urea content, aspartate aminotransferase (AsAT) activity, alanine aminotransferase (AlAT) activity are presented), as well as the economic efficiency of research results is calculated. The study was conducted in LLC "Druzhba-Kaznacheyivka"of Dnipropetrovsk region, in the Research center of biosafety and ecological control of agricultural resources of Dnipropetrovsk state agrarian and economic university, meat processing plant «Jazz» and Laborator Livestock y of the State institution Institute of grain crops of NAAS of Ukraine. The work was performed according to the research program of NAAS of Ukraine №30 "Innovative technologies of breeding, industrial and organic production of pig products" ("Pig breeding"), state registration number 0116U001247. The object of the study was young pigs of large white breed. Evaluation of animals for fattening and meat qualities was carried out taking into account the following indicators: average daily live weight gain during the control period of fattening, g, age of live weight 100 kg, days, fat thickness at the level of 6-7 thoracic vertebrae, mm, length of chilled carcass , cm, the length of the bacon half of the cooled half-carcass, cm (M.D. Berezovsky, I.V. Kha’tko, 2005). A comprehensive assessment of young pigs for fattening and meat qualities was calculated according to the B. Tailer index (P.A. Vashchenko, 2019), biometric indicators - according to the methods of G.F. Lakin (1990). Economic efficiency of research results was calculated according to the generally accepted technique (Methodology for determining the economic ..., 1983). It was found that the urea content, activity of aspartate aminotransferase (AsAT) and alanine aminotransferase (AlAT) in the serum of young pigs of the experimental group corresponds to the physiological norm of clinically healthy animals and amount to 4.77±0.576 mol/l, 68.11±6.445 units/l, and 4.22±3.209 units/l, respectively. According to the age of reaching a live weight of 100 kg (days), the thickness of the fat at the level of 6-7 thoracic vertebrae (mm) and the length of the chilled carcass (cm) of the specified production group and breed correspond to class I and class "elite". The maximum values of "average daily gain of live weight during the period of control fattening, kg", "length of chilled carcass, cm", "length of bacon half of chilled carcass, cm" and minimum values of "age of live weight 100 kg, days" and "fat thickness per levels of 6-7 thoracic vertebrae, mm "are characterized by animals in which the complex index of fattening and meat qualities (B. Tailer's index) ranges from 157.68 to 182.36 points. The number of reliable relationships between the biochemical parameters of blood serum, fattening and meat qualities of young white pigs is 26.67 %. The cost of additional products obtained from young pigs with B. Tailer index of 157.68 – 182.36 points is equal to +1732.04 UAH/head.


2009 ◽  
Vol 33 (1) ◽  
pp. 38-43
Author(s):  
Motthena Mahmoud Shaker

The objective of this study was to determine the effect of adding aspirin to the diet on somebiochemical parameters such as blood serum glucose , cholesterol , uric acid , total protein ,phosphorus and calcium concentrations of broilers reared in high density (15 birds / m ) . A 90 chicks 7days old were distributed into two treatments (45 chicks per treatment ) , T1 chicks fed a diet withoutaspirin (control) , chicks in T2 fed a diet supplemented with 0.2 % aspirin (2 mg aspirin / kg feed) .Each treatment subdivided into three replicates and each replicate reared in 1 X 1 m pen . The dataobtained revealed the following:Blood serum glucose concentration were 189 mg /100 ml , cholesterol concentration were 207mg /100 ml , uric acid concentration were 4.6 mg /100 mll of T1 chicks at 7 weeks of age , adding 0.2% of aspirin to the diet (T2) decreased blood serum glucose , cholesterol and uric acid of broiler chicksto 178 , 182 and 4.2 mg /100 ml respectively , in the same time adding aspirin to the diet increasedsignificantly (P<0.01) total protein concentration which were 5.1 gm /100 ml compaired with 4.6gm/100 ml of control chicks (T1) at 7 weeks of age . Adding aspirin to the diet increased significantly(P<0.01) blood serum phosphorus and calcium concentrations which indicated the importance ofadding aspirin in broiler diet to rebalance blood biochemical parameters and reducing crowding stressduring high density production


2020 ◽  
Vol 10 (1) ◽  
pp. 158-161 ◽  
Author(s):  
V. Khalak ◽  
B. Gutyj ◽  
O. Bordun ◽  
M. Ilchenko ◽  
A. Horchanok

The article presents the results of studies of fattening and meat qualities of young white pigs of different white breeds of different intensity of formation (Δt) in early ontogeny, biochemical parameters of blood serum (aspartate aminotransferase activity, alanine aminotransferase, alkaline transferase, alkaline phosphatase. It is established that according to the main indicators of fattening and meat qualities (age of reaching live weight of 100 kg, days; thickness of the sleeve at the level of 6-7 thoracic vertebrae, mm; length of chilled carcass, mm) young pigs of the controlled herd belong to the first class and class elite, and serum biochemical parameters are consistent with the physiological norm of clinically healthy animals. Taking into account the class of distribution by intensity of formation (Δt), a significant difference was established between animals of I (Δt = 0.795–0.832) and III (Δt = 0.660–0.703) groups on the average daily gain of live weight and age of reaching live weight of 100 kg. The relationship between the biochemical parameters of serum, fattening and meat characteristics of young pigs ranges from -0.250 to +0.385 and is unlikely. We offer in breeding and breeding work, along with the traditional methods of evaluation and selection of high-yielding animals use the method of evaluation and breeding indices.


2021 ◽  
Vol 1 (1) ◽  
pp. 90-95

The article analyzes the seasonal dynamics (winter, summer) of morphological and biochemical blood indicators characterizing the adaptive plasticity to the external environment of steers of locally improved livestock, Aberdeen-Angus, Kazakh white-headed and Kalmyk breeds, grown after weaning from mothers at the age of 8 months at an open feedlot of industrial type, located in a mountainous area within 1600 m above sea level. It was found that gobies of specialized meat breeds in all seasons of the year were characterized by greater blood saturation with red blood cells and hemoglobin and had an advantage over local improved cattle in terms of the content of total protein, albumins and globulins in blood serum.


2021 ◽  
Vol 291 ◽  
pp. 02007
Author(s):  
Elena Ulrikh ◽  
Olga Babich ◽  
Stanislav Sukhikh

During the study, it was found that an increase in the dose of sweet yellow clover extract from 0.5 to 2.5 mg/kg of live weight per day contributed to an increase in the number of: hemoglobin by 1.83 g/l (1.79%), leukocytes by 0.14 thousand 109/l (2.34%), total protein in blood serum of sheep by 0.43 g/l (0.7%), glucose in blood of sheep by 0.18 mmol/l (4.19%), calcium in blood of sheep by 0.14 mmol/l (5.32%), phosphorus in blood of sheep by only 0.08 mg/100 ml (1.6%), contributed to an increase in the live weight of sheep by 220 g (2.18%). In the control group, two sheep out of six got bronchitis. The percentage of sheep with bronchitis was 33.33%. After feed to the sheep different doses of sweet yellow clover extract, the sheep in groups I and II of the experimental groups had one sheep each (16.67%), while in groups III, IV and V there were no sheep with bronchitis. Thus, increasing the sweet yellow clover dosage in sheep’ diet reinforced their immunity. In the control group and in the first experimental group, one sheep out of six came down with dyspepsia. The percentage of sheep with dyspepsia was 16.67%. After feed to the sheep doses of sweet yellow clover extract, there were no dyspeptic diseases in sheep.


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