scholarly journals Use of sweet yellow clover (Melilotus officinalis) extract in sheep feeding

2021 ◽  
Vol 291 ◽  
pp. 02007
Author(s):  
Elena Ulrikh ◽  
Olga Babich ◽  
Stanislav Sukhikh
Keyword(s):  
Blood Serum ◽  
Total Protein ◽  
Live Weight ◽  
Control Group ◽  
Melilotus Officinalis ◽  
Experimental Group ◽  
Different Doses

During the study, it was found that an increase in the dose of sweet yellow clover extract from 0.5 to 2.5 mg/kg of live weight per day contributed to an increase in the number of: hemoglobin by 1.83 g/l (1.79%), leukocytes by 0.14 thousand 109/l (2.34%), total protein in blood serum of sheep by 0.43 g/l (0.7%), glucose in blood of sheep by 0.18 mmol/l (4.19%), calcium in blood of sheep by 0.14 mmol/l (5.32%), phosphorus in blood of sheep by only 0.08 mg/100 ml (1.6%), contributed to an increase in the live weight of sheep by 220 g (2.18%). In the control group, two sheep out of six got bronchitis. The percentage of sheep with bronchitis was 33.33%. After feed to the sheep different doses of sweet yellow clover extract, the sheep in groups I and II of the experimental groups had one sheep each (16.67%), while in groups III, IV and V there were no sheep with bronchitis. Thus, increasing the sweet yellow clover dosage in sheep’ diet reinforced their immunity. In the control group and in the first experimental group, one sheep out of six came down with dyspepsia. The percentage of sheep with dyspepsia was 16.67%. After feed to the sheep doses of sweet yellow clover extract, there were no dyspeptic diseases in sheep.

scholarly journals Stress state and immunological status of young pigs

2019 ◽  
pp. 95-98
Author(s):  
M. V. Chornyi
Keyword(s):  
Stress State ◽  
Blood Serum ◽  
Bactericidal Activity ◽  
Total Protein ◽  
Live Weight ◽  
Natural Resistance ◽  
Control Group ◽  
Immunological Status ◽  
Young Pigs ◽  
Experimental Group

The paper presents the results of studies on the effect of regrouping of piglets at different ages on the resistance of their organisms, immunological status, productive qualities and safety of young pigs. The work was performed at “Stas” LLC on large white breed pigs and their crossbreeds. For the experiment, three groups of piglets were formed from suckling sows — analogues. In the experiment 60 animals from birth up to two months of age were used, 20 animals in each experimental group. The control group of piglets was raised from birth up to 60 days of age in nests, and then they were moved to the rearing workshop; Experimental 1 group was kept up to 10 days old in nests, and then a one-time rearrangement was performed according to live weight. Piglets from experimental group 2 were regrouped according to live weight at 5, 10, 15, 21, 30 days of age. To assess the natural resistance of piglets due to the above groups, hematological, biochemical (total protein, protein fractions) methods, immunological (immunoglobulins of classes IgA, IgM, IgG), and natural resistance (bactericidal activity of blood serum) were used, serum lysozyme activity (LASK), phagocytic neutrophil activity (FAN), phagocytic index (FI), ethological, zootechnical, mathematical. To assess the natural resistance of piglets the following research methods were used: generally accepted zoo veterinary methods (live weight, morbidity, safety), hygienic (microclimate conditions, sanitary regime), hematological (morphological blood composition), biochemical (total protein, protein fractions), immunological (immunoglobulins of classes IgA, IgM, IgG), natural resistance (bactericidal activity of blood serum), ethological and mathematical methods. Results of work. It was found that when growing piglets, nesting, without moving, caused their growth and development without any noticeable physiological disturbances, both from the blood and ethology. In animals (Experimental-1 groups) which underwent a single regrouping in a 10 day reward, their lag in live weight by 12.65% was recorded, compared with the control, with two and three-time movement (Experimental-2) — by 16.10%. Their SSPs were 28% less and 14.7% lower than in the control piglets. Patients with symptoms of diarrhea were identified in the control: in 3–4 daily reimbursement — 1%, in Experimental-1 — 5%, Experimental-2 — 10–15%. The resistance of young animals to gastrointestinal diseases according to the Melenberg coefficient in the Experimental-2 group was 6.13–7.48, in control group it was 0.34, and the safety did not exceed 80.2%. According to the level of immune status, animals from Experimental-2 group were inferior: by BASK — by 25.15% (28 days of age), by LASK — by 7.56%, by FAN — by 10.7% compared with peers from Experimental-1 groups. By the number of eosinophils (Experimental-2 group), characterizing the stress state of piglets, their decrease was observed within 10–12 days, not more than 5 days — in animals from Experimental-1 group and up to 3 days — from control

scholarly journals REASIL HUMICVET AND REASIL HUMIC HEALTH SUPPLEMENTS BASED ON HUMIC ACIDS IN THE DIETS OF DAIRY CALVES

2021 ◽  
Vol 6 (1) ◽  
pp. 64-70
Author(s):  
Andrei Frolkin ◽  
Haidar Valitov ◽  
Aleksandr Varakin ◽  
Valentina Kornilova
Keyword(s):  
Blood Serum ◽  
Live Weight ◽  
Mineral Elements ◽  
The Body ◽  
Control Group ◽  
Liquid Form ◽  
Daily Growth ◽  
Black And White ◽  
Significant Difference ◽  
Experimental Group

The purpose of the research is to increase the effectiveness of the supplement Reasil on the growth of milk-fed calves. For the scientific and economic experience, three groups of calves were formed (control, 1 and 2 experi-enced). Groups of animals of 10 heads were formed according to the principle of analogues. The indicators of live weight, growth and blood of calves were studied after Reasil use in a diet: Reasil HumicVet as a liquid form, and Reasil Humic Health – reduced to powder. In the experiment, animals of a black-and-white breed were used. The Reasil feeding in the diet contributed to an increase in the live weight of milk-fed calves in the 1-st and the 2-nd experimental groups at two months of age by 5.65 and 5.48 kg (or by 7.4 and 7.2%), respectively, compared to the indicator of the control group analogues. The average daily growth of calves of the experimental groups exceeded this indicator of control animals by 96 and 82 g, respectively. The blood of calves of the 1st and 2nd experimental groups, showed that hematoglobin was higher by 15.7 and 11.4%, red blood cells – by 16.5 and 15.1%, and the alkaline reserve – by 5.2%, compared with blood of calves from the control group, which indicates the activation of metabolic processes in the body. The total protein amount in the blood serum of animals from the experimental groups increased by 8.4 and 5.9% respectively, compared to the tests of calves from the control group. The albu-min content of animals of the 1st experimental group tested was higher by 5.3%; from the 2nd experimental group there was no significant difference compared to the control. The number of gamma-globulins in the blood of ani-mals of the experimental groups increased, which indicates an increase in defense reaction of animals. The con-tent of calcium in the blood serum of calves from the experimental groups was higher by 8.3 and 5.9%, phosphorus – by 4.8 and 2.4%, which indicates a more effective use of these mineral elements.

Fattening of young pigs when using the compound feed with the inclusion of smectic kizelgur and calf skim milk replacer

2020 ◽  
pp. 13-26
Author(s):  
L. Gamko ◽  
M. Badyrkhanov
Keyword(s):  
Average Daily Gain ◽  
Skim Milk ◽  
Live Weight ◽  
Milk Replacer ◽  
Control Group ◽  
Pork Production ◽  
Young Pigs ◽  
Daily Gain ◽  
Experimental Group ◽  
Different Doses

The purpose of the researches was to study the influence of different doses of smectic kizelgur and calf skim milk replacer in the recipes of compound feed for young pigs under the conditions of industrial pork production technology. The experimental part of the work has been performed under the conditions of the pig complex of LLC “BMPK” in the Karachevsky area in the Bryansk region. The research materials were compound feed for young pigs on fattening in the inclusion of different doses of smectic kizelgur. The infl uence of feeding compound feed with different doses of smectic kizelgur and calf skim milk replacer to young pigs on productivity, digestibility of nutrients and use of nitrogen, morphological and biochemical parameters of blood, fattening and meat traits of young pigs has been studied. Effective recipes for feeding compound feeds to young pigs prepared with the inclusion of different doses of smectic kizelgur and calf skim milk replacer have been identified. The data have been obtained from the first experiment of young pigs when them fed compound feed with different doses of smectic kizelgur; it has been followed that at the end of fattening the biggest live weight of gilts had in the 4th experimental group fed compound feed, which included 3 % smectic kizelgur. The influence of the additive on changes in live weight and daily gains when adding smectic kizelgur to compound feed in doses of 1,5 and 2,0 % was less, but the trend to increase these indicators over the period of fattening has remained. In the second experiment young pigs have been fed by compound feed, which included different doses of smectic kizelgur and calf skim milk replacer the average daily gain in live weight was higher in the 3rd experimental group, where they fed compound feed with the addition of 2,5 % smectic kizelgur and 2,5 % calf skim milk replacer by 2,2 %, than in the control group. The highest efficiency has been also obtained in the 3rd experimental group, where the monetary revenue has been received by 2160 rubles more in comparison with the control group of pigs.

Growth rate and conformation characteristics of calves after administration of different doses of tissue biostimulator to cows

2021 ◽  
pp. 9-15
Author(s):  
I. A. Pushkaryev ◽  
T. V. Kureninova ◽  
T. L. Silivirova ◽  
N. V. Shanshin
Keyword(s):  
Growth Rate ◽  
Live Weight ◽  
Control Group ◽  
Physiological Status ◽  
Tissue Preparation ◽  
Black And White ◽  
White Breed ◽  
The Impact ◽  
Experimental Group ◽  
Different Doses

It is known that one of the most important reasons for the birth of weak calves is the impact of adverse factors on the physiological status of the cow, which in turn affects the intrauterine and postnatal development of the fetus and newborn. The results of studying the introduction of different doses of tissue biostimulator to cows during the dry period and its effect on the development of the conformation of calves received from them have been presented in the article. The experiment was carried out in 2019 on cows of Priobsky type of Black-and-White breed and calves obtained from them. In order to conduct the experiment four groups of dry cows-analogs have been formed with 10 heads in each for 55–60 days before the expected calving at the age of III lactation and older. When selecting animals the live weight and milk productivity of cows for the previous lactation have been taken into account. The highest growth rate has been observed in calves from cows the 2nd experimental group, which exceeded the control by 24,4 % (P ≤ 0,001). The best indicators of conformation development have been also observed in calves obtained from cows of the 2nd experimental group, which were injected subcutaneously with 22,5 ml of tissue preparation. So, oblique body length have been greater by 12,6 % (P ≤ 0,001), chest girth by 17,3 % (P ≤ 0,001), width of hook bones by 21,0 % (P ≤ 0,01), the width of the pin bones by 15,0 % (P ≤ 0,05). The lengthiness index was by 11,5 % higher (P ≤ 0,001), the blockiness index was by 4,1 % higher (P ≤ 0,05), and the boniness index was by 10,6 % lower (P ≤ 0,05) than in the control group herdmates.

scholarly journals Productivity and resistance of pigs under the action of immunostimulants

2017 ◽  
Vol 19 (79) ◽  
Author(s):  
N. V. Chorniy ◽  
O. S. Machula ◽  
V. V. Voronyak ◽  
V. P. Lyasota ◽  
O. P. Reshetnichenko
Keyword(s):  
Blood Serum ◽  
B Lymphocytes ◽  
Live Weight ◽  
The Body ◽  
Control Group ◽  
Average Weight ◽  
Large White ◽  
Immunological Parameters ◽  
Humoral Factors ◽  
Experimental Group

The aim of the work was to study the influence of stimulant drugs – the regenerating biological stimulant (RBS) and Imunolac on the immunological state and productive qualities of piglets. RBS is a complex of organic compounds of animal tissue that stimulates nonspecific immunity and increases the protective functions of the body. Imunolac is a preparation of enzymatic hydrolysis of the cell wall of Lactobacillus, activating the cellular and humoral factors of non-specific animal resistance. To achieve this goal, the following tasks were set: to find out the microclimate condition and sanitary regime in the boxes in which the experimental animals were kept; – to study the influence of immunostimulating drugs on the growth and intensity of the test pigs, their safety; to study the dynamics of immunological parameters (circulating immune complex (CIC), T-and B-lymphocytes), the content of immunoglobulins (Jg G, Jg M and Jg A) while using RBS and Imunolac. The research was carried out in the pedigree plant «Stepnoy» of the Zaporozhye region on pigs of the Large white breed × Landras. Piglets of the control group were injected with 0.9% sodium chloride solution at a dose of 1 ml/head. During the experiment, the microclimate was monitored for temperature, relative humidity, air speed, carbon dioxide, ammonia, air contamination with microflora. Cellular indices were determined from the ratio of neutrophils to E. coli according to VG Gostivu, 1956, bactericidal activity of blood serum (BASK) – according to the method of O.V. Smirnova and TA. Kuzmenoy, 1966, lysozyme activity of blood serum (LASK) according to V. Dorofeychuk, 1968. The content of T lymphocytes was determined according to M. Jondal, 1973, B-lymphocytes – according to N.S. When piglets were grown at the temperature lower than 3,5–8 °C, humidity – by 5–8% higher, the parameters of NH3 and CO2 higher by 0.8–1.2%, the contamination microflora was twice as much as recommended by the sanitary norms the genetic productive potential of the animals is not fully realized, while – the highest daily average weight gain was in the pigs, which were injected intramuscularly with RBS growth stimulant. They exceeded the animals from the control group on the 20th and 30th days of the experiment – by 24.3% and 14.4%, live weight – by 15.3% (P < 0.05). The growth rate in the animals that were injected with imunolac was less expressed; the diseases with the symptoms of dyspepsia and bronchopneumonia were registered in 5–10% of the pigs from the experimental groups that received RBS and imunolac that is 10–12 times less as compared to the control group; in the pigs from the experimental group 1, the BASK was at the level of the average values of 56.52 ± 2.03%, from the experimental group 2 – 59.48 ± 1.80%, by 5.2% higher (P < 0.05); LASK indices in the animals of the experimental group tended to increase but the differences were not trustworthy (P < 0.5); the cell indices of resistance in the pigs that received RBS were higher: the phagocytic activity of blood serum – by 4.3% (P < 0.05), phagocytic number – by 9.7% (P <0.05); the highest concentration of immunoglobulin of class Jg G (21.82 ± 0.3 mg/ml) was revealed in the animals that received RBS preparations, the concentration of the above immunoglobulins was slightly below – 19.86 ± 0.18 mg/ml in the pigs that received imunolac (0–1). For immunoglobulins of class Jg M and Jg A, the fluctuations  between the experimental groups were within the limits of 2.23 ± 0.01 and 2.36 ± 0.09 mg/ml.

scholarly journals Effect of thyme extract on fertility and survival of ISA F-15 broilers

2018 ◽  
pp. 74-80
Author(s):  
Е. A. Kishniaikina ◽  
К. V. Zhuchaev
Keyword(s):  
Weight Gain ◽  
Production Efficiency ◽  
Live Weight ◽  
Productivity Index ◽  
Feed Consumption ◽  
Control Group ◽  
Production Cycle ◽  
Feed Costs ◽  
Experimental Group ◽  
Different Doses

The paper highlights the research conducted in order to assess the effect of different doses of thyme extract on the productive properties and livability of broiler chickens. The experiment was conducted at a broiler poultry farm with a closed production cycle; the experiment assumed the control group and 5 experimental groups where each group contained 37 broilers at floor housing. The broilers of the 1st experimental group were fed with the extract of medicinal plant thyme dosed 2 mg/kg; broilers of the 2nd group received thyme extract dosed 4 mg/kg; 3rd group of broilers – 6 mg/kg, 4th group -8 mg/kg, and the dosage of the thyme extract was 10 mg/kg for broilers in the 5th experimental group. The authors controlled the live weight of broilers in each group by means of individual weighing every 7 days. Using this data the researchers calculated average daily body weight gain, absolute and relative gain; feed consumption was daily calculated. Feed consumption became the basis for calculating feed costs per a kilo of live weight gain. The authors recorded the number of daily fallen chickens. The data on poultry loss was the basis for calculating poultry livability. In order to assess production efficiency, the European productivity index was calculated. The research results indicate the efficiency of thyme extract application in different doses when feeding the broiler. Application of thyme extract in feeding meat poultry allowed to increase productive properties of broilers from experimental groups from 2.3 to 4.7%, reduce feed costs per a kilo by 1.1-8.1%, increase poultry livability on 2.7-8.1% and increase the European productivity index in the experimental groups on 0.2 21.3%.

scholarly journals THE IMPACT OF VETOM 20.76 BASED ON PREDATORY FUNGUS ARTHROBOTRYS OLIGOSPORA ON THE LEUCOCYTES IN THE GEESE BLOOD

2019 ◽  
pp. 103-108
Author(s):  
N. S. Iakovleva ◽  
G. A. Nozdrin ◽  
M. S. Iakovleva ◽  
S. N. Tishkov ◽  
A. I. Shevchenko
Keyword(s):  
Live Weight ◽  
Control Group ◽  
Group 2 ◽  
The Impact ◽  
Higher Doses ◽  
Leukocyte Concentration ◽  
Experimental Group ◽  
Different Doses ◽  
Group 1

The paper demonstrates the results on the effect of new specimen Vetom 20.76 on concentration of leukocytes in the blood of geese on the basis of the predatory fungus Artusbotus oligospora. In order to achieve the goal of the experiment, one control group and six experimental groups were arranged on the principle of paired analogues. Each group contained 10 geese aged 1 month. The geese from the experimental groups received Vetom 20.76 in different doses in the morning with water once a day: the geese of the 1st experimental group - dose of 0.5 ppm/kg of live weight during 15 days; 2nd experimental group - 1 ppm/kg of live weight during 15 days; 3rd experimental group - 2 ppm/kg of live weight during 15 days, 4th experimental group - 0.5 ppm/kg live weight during 30 days, 5th experimental group - 1 ppm/kg live weight during 30 days and 6th - 2 ppm/kg live weight during 30 days. The geese of control group didn’t receive the specimen. The concentration of leukocytes in the blood of experimental geese increases in the period of specimen application as well as in the period of its aftereffect. If Vetom 20.76 is prescribed for 15 days, the effect of leukopoiesis stimulation finishes on the 30th day. If the specimen is applied during 30 days, the leukocytes in the blood continue to increase up to the 60th day. This long-term application of Vetom 20.76 dosed 0.5ppm/kg increases leucocytes within the physiological norm. Application of higher doses (1 and 2 ppm/kg) the leukocyte concentration conforms to the physiological norm

INFLUENCE OF DIFFERENT DOSES OF TISSUE BIOSTIMULANT ON BIOCHEMICAL BLOOD INDICES OF YOUNG CATTLE

2021 ◽  
pp. 40-43
Author(s):  
И.А. ПУШКАРЕВ ◽  
А.И. АФАНАСЬЕВА ◽  
Т.В. КУРЕНИНОВА
Keyword(s):  
Blood Serum ◽  
Live Weight ◽  
Cholesterol Content ◽  
Control Group ◽  
Total Protein Content ◽  
Trial Group ◽  
Mesenteric Lymph Nodes ◽  
Blood Indices ◽  
Young Cattle ◽  
Different Doses

Изучено влияние введения разных доз тканевого биостимулятора на биохимические показатели сыворотки крови ремонтного молодняка крупного рогатого скота. Опыт проводился в Алтайском крае на 4 группах ремонтных телочек Приобского типа черно-пестрой породы по 10 голов в каждой. При подборе животных учитывались возраст (1 мес) и живая масса (51,3±1,48 кг). Продолжительность опыта составляла 14 дней. Животным контрольной группы подкожно однократно вводили физиологический раствор в дозе 3,0 мл на 1 голову, I опытной — тканевый биостимулятор в дозе 2,0 мл, II — 3,0 мл, III — 4,0 мл на 1 голову. Опытную партию тканевого биостимулятора изготовили из субпродуктов и боенских отходов пантовых оленей по запатентованной технологии. Материалом для приготовления препарата служили мезентеральные лимфоузлы и средостения, селезенка, печень, матки с плодами (2—3 мес), плацента, отобранные в асептических условиях во время убоя здоровых животных. Введение тканевого биостимулятора телочкам в разных дозах способствовало повышению некоторых исследуемых биохимических показателей сыворотки крови. Наиболее оптимальной дозой применения тканевого биостимулятора следует считать 3,0 мл/гол, что способствует повышению содержания общего белка в сыворотке крови на 1,4% (P≤0,05), глюкозы — на 22,6% (P≤0,05) и снижению содержания холестерина на 12,3% (P≤0,05). The effect of the administration of different doses of the tissue biostimulant on the biochemical blood serum indices of replacement young cattle was studied. The experiment was carried out in the Altai Region in 4 groups of 10 Black-Pied replacement heifers of the Priobskiy type. When selecting the animals, their age (1 month) and live weight (51.3±1.48 kg) was taken into account. The experiment lasted 14 days. Saline solution was injected under the skin to the animals of the control group at a dose of 3.0 mL per 1 head; the tissue bio-stimulant was administered in the following doses: in the 1st trial group — 2.0 mL per head; the 2nd trial group 3.0 mL per head; the 3rd trial group — 4.0 mL per 1 head. The trial batch of the tissue bio-stimulant was made from velvet antler deer by-products and slaughterhouse offal by using the patent-protected technology. The tissue biostimulant was made from mesenteric lymph nodes and mediastinums, spleen, liver, uteri with 2—3 month old fetuses, and placentae collected under aseptic conditions from healthy animals at slaughter. The administration of the tissue bio-stimulant to heifers in different doses increased some of the studied biochemical blood serum indices. The tissue biostimulant dose of 3.0 mL per head should be considered the most optimal one; it increased the total protein content in blood serum by 1.4% (P≤0.05), glucose — by 22.6% (P≤0.05), and decreased cholesterol content by 12.3% (P≤0.05).

PREVENTION AND CORRECTION OF DISORDERS OF THE METABOLISM OF PIGS WITH THE USE OF NATURAL FEED ADDITIVES

2021 ◽  
Vol 1 (2) ◽  
pp. 189-194
Author(s):  
L.A. Nikanova ◽  
◽  
E.N. Kolodina ◽  
R.A. Rykov ◽  
◽  
...  
Keyword(s):  
Blood Serum ◽  
Total Bilirubin ◽  
Live Weight ◽  
Feed Additives ◽  
The Body ◽  
Control Group ◽  
Blue Green Algae ◽  
Adaptive Ability ◽  
Positive Effect ◽  
Experimental Group

This article presents the results of studies conducted on piglets with the inclusion of natural feed additives in the diet in order to prevent and correct metabolism. The first experimental group of piglets received a total diet consisting of fullfledged compound feed, a complex micro-feed product consisting of blue-green algae Spirulina, dihydroquercetin and organic iodine, the second experimental group additionally received Spirulina and dihydroquercetin. The introduction of these natural feed additives into the diet of piglets helped to increase the adaptive ability , correction and prevention of metabolic disorders in the body. In these studies, dacha feed supplements prevented hyperbilirubinemia. As a result, the concentration of total bilirubin in the blood serum of pigs of the first experimental group was 1% lower, in the second experimental group it was 13,7% lower than in the control group. They also had a positive effect on the functional state of the liver, as evidenced by a lower content of AlAT and AsAT activity in the blood serum compared to those in piglets of the control group with a close cholesterol-forming fraction. The animals of the experimental group were less ill and the safety of this group was 100%, in the control group it was 90%. The average daily increase in live weight of pigs for 90 days in the first experimental group was 1% higher than in the control group, and in the second experimental group it was 21,7% higher.

scholarly journals DYNAMICS OF PROTEIN METABOLISM IN COWS WITH PROBIOTIC VETOM 1 BASED ON APATHOGENIC BACILLI

2019 ◽  
pp. 73-78
Author(s):  
G. A. Nozdrin ◽  
O. V. Lagoda ◽  
K. E. Surodina ◽  
A. G. Nozdrin ◽  
O. M. Gorshkova
Keyword(s):  
Blood Serum ◽  
Total Protein ◽  
Protein Metabolism ◽  
Biochemical Parameters ◽  
Control Group ◽  
Lactating Cows ◽  
Experimental Group

The researchers investigated the effect of new probiotic Vetom 1 based on apathogenic bacilli on the biochemical parameters of blood serum, exactly protein, albumins and urea in lactating cows. The experiment was carried out at OOO “Uchkhoz Tulinskoe”. According to the principle of pair-analogues, the researchers arranged a control group and two experimental groups of cows; each group contained 7 cows. The cows of the 1st experimental group were fed with probiotic Vetom 1 dosed 50 mg/kg once a day in the morning before milking; They received Vetom 1 every day during 5 days, then in a day during a month. The cows from the 2nd experimental group received probiotic Vetom 1 dosed 50 mg/kg once a day in the morning before milking, every day during 30 days. The application of the specimen contributed to a decrease in the concentration of total protein in the blood serum within the physiological norm. The aftereffect caused by Vetom 1 when the specimen was applied 5 days every day, then in a day during a month, the authors observed an increase in the concentration of total protein in the blood serum above the physiological standard on the 180 day of application. The similar effect was not observed when Vetom 1 was applied daily. When using Vetom 1, the authors observed a slight increase in the concentration of albumins in the blood serum, both during the period of application and up to 180 days. The specimen contributes to less prominent increase in the concentration of urea in the blood serum in comparison with the control group. Changes in concentrations of albumins and urea occurred within the physiological norm.

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