The Organization of Cooperative Effort by Multiple Hospitals, Exemplified by Testing of Therapeutic Agents in Rheumatoid Arthritis

1962 ◽  
Vol 01 (01) ◽  
pp. 06-09 ◽  
Author(s):  
Lee Herrera
Keyword(s):  
Clinical Investigation ◽  
Therapeutic Agents ◽  
Random Allocation ◽  
Patient Assessment ◽  
Cooperative Effort ◽  
Study Population ◽  
Advance Planning ◽  
Definition Of ◽  
Multi Center Study ◽  
The Cost

The advantage of a multi-center clinical investigation lies in the possibility of obtaining conclusive results on the basis of relatively few numbers of patients from each of the participating institutions. It has the disadvantage of a lack of uniformity of methods among centers, which must be overcome by careful advance planning, including the institution of a central coordinating unit, the biometrical unit. Its functions include (1) participation in the planning of all phases of the investigation, (2) editing and processing of the data, and (3) analysis of the data and evaluation of results.Three devices for promoting uniformity of methods are: (1) the protocal, (2) specially designed record forms, and (3) visits to participating centers by a team of observers, including the statistician. The protocol is the document which contains all important specification for the conduct of the investigation, including statement of purpose of the study, definition of the study population, and explicit instructions on methods of patient assessment.In a clinical trial, the biometrical unit prepares the random allocation of treatments to patients. Stratification may be used to make comparisons between strata, and/or increase the sensitivity of the experiment. Stratification by exclusion may increase sensitivity at the cost of restricting the generality of results.A well-planned multi-center study, in which the members really cooperate, may achieve objectives exceeding the scope of single-center studies and provide a setting for the fruitful exchange of knowledge and ideas.

Constructing Images of Deviance: A Look at State Intervention into the Problem of Wife-Battery

1983 ◽  
Vol 31 (1_suppl) ◽  
pp. 60-76
Author(s):  
Patricia A. Morgan
Keyword(s):  
Social Problem ◽  
State Intervention ◽  
The United States ◽  
The State ◽  
Structural Position ◽  
Wife Battering ◽  
The Social ◽  
Class Context ◽  
Definition Of ◽  
The Cost

Patricia Morgan's paper describes what happens when the state intervenes in the social problem of wife-battering. Her analysis refers to the United States, but there are clear implications for other countries, including Britain. The author argues that the state, through its social problem apparatus, manages the image of the problem by a process of bureaucratization, professionalization and individualization. This serves to narrow the definition of the problem, and to depoliticize it by removing it from its class context and viewing it in terms of individual pathology rather than structure. Thus refuges were initially run by small feminist collectives which had a dual objective of providing a service and promoting among the women an understanding of their structural position in society. The need for funds forced the groups to turn to the state for financial aid. This was given, but at the cost to the refuges of losing their political aims. Many refuges became larger, much more service-orientated and more diversified in providing therapy for the batterers and dealing with other problems such as alcoholism and drug abuse. This transformed not only the refuges but also the image of the problem of wife-battering.

scholarly journals Application Of The Work Breakdown Structure In Determining Cost Buffers In Construction Schedules

2015 ◽  
Vol 61 (1) ◽  
pp. 147-161 ◽  
Author(s):  
M. Połoński
Keyword(s):  
Construction Projects ◽  
Work Breakdown Structure ◽  
Initial Task ◽  
The Common ◽  
Definition Of ◽  
The Cost ◽  
Construction Schedules

AbstractThe paper presents methods of determining the location of cost buffers and corresponding contingency costs in the CPM schedule based on its work breakdown structure. Application of correctly located cost buffers with appropriately established reserve costs is justified by the common overrunning of scheduled costs in construction projects. Interpolated cost buffers (CB) as separate tasks have been combined with relevant summary tasks by the start–to–start (SS) relationship, whereas the time of their execution has been dynamically connected with the time of accomplishment of particular summary tasks using the “paste connection” option. Besides cost buffers linked with the group of tasks assigned to summary tasks, a definition of the cost buffer for the entire project (PCB) has been proposed, i.e. as one initial task of the entire project. Contingency costs corresponding to these buffers, depending on the data that the planner has at his disposal, can be determined using different methods, but always depend on the costs of all tasks protected by each buffer. The paper presents an exemplary schedule for a facility and the method of determining locations and cost for buffers CB and PCB, as well as their influence on the course of the curve illustrating the budgeted cost of work scheduled (BCWS). The proposed solution has been adjusted and presented with consideration of the possibilities created by the scheduling software MS Project, though its general assumptions may be implemented with application of other similar specialist tools.

Analisis Pembiayaan Dana Talangan Haji untuk  Biaya Perjalan Ibadah Haji

2018 ◽  
Vol 1 (2) ◽  
pp. 228-244
Author(s):  
Asmawarna Sinaga ◽  
Anjur Perkasa Alam ◽  
Fariz Arkan ◽  
Sri Wahyuni Hasibuan
Keyword(s):  
Islamic Law ◽  
Field Research ◽  
Interactive Methods ◽  
Islamic Banks ◽  
Data Presentation ◽  
Analysis Techniques ◽  
Collection Data ◽  
Definition Of ◽  
The Cost

  Analysis of the amount of financing the hajj bailout for the cost of the pilgrimage (Case Study of Bank Sumut Syariah Sub-Branch Stabat).Asmawarna Sinaga and Anjur Perkasa Alam. Hajj financing is a loan from a sharia bank to customers to cover the shortage of funds to obtain a seat (seat) Hajj at the time of repayment BPIH (Hajj Travel Expenses). This financing product uses the Qardh Wal Ijarah principle. The purpose of this research is to know the view of Islamic law against financing of Hajj bailout fund and to know the view of Islamic law about ujrah fee on akad of bailout fund of Hajj. This research is field research. The definition of the Hajj bailout is a bailout fund from a bank to a special customer to cover kekurangandana to cover the lack of funds to obtain a portion number at the time to pay the cost of organizing the pilgrimage. The research design uses a qualitative approach with non-statistical analysis While the data analysis techniques use content analysis and interactive methods consisting of data reduction, data collection, data presentation and conclusion. The results of this study note that the akad bailout funds in Islamic banks contain multi-akad, where the contract used qardh and ijarah is allowed. While the view of Islamic law regarding the taking of ujrah fee on hajj bailout fund is not in accordance with sharia due to the percentage of ujrah fee based on qardh fund.

Influence of inter-organizational relations on methods of calculating the cost of production of agricultural organizations

2020 ◽  
pp. 13-20 ◽  
Author(s):  
Anastasiya Alekseevna Romanova
Keyword(s):  
Theoretical Analysis ◽  
Cost Calculation ◽  
Interorganizational Cooperation ◽  
Organizational Relations ◽  
Interorganizational Management ◽  
Calculation System ◽  
Analytical System ◽  
Definition Of ◽  
The Cost ◽  
Organizational Cooperation

The author’s definition of inter-organizational cooperation, interorganizational management accounting and inter-organizational accounting and analytical system and cost calculation system in the framework of inter-organizational relations is given in the article on the basis of theoretical analysis. The features of calculating the cost of interorganizational cooperation are defined, new accounting practices are described, the advantages of implementing this type of accounting are identified, and possible problem areas are identified.

ProQuest Historical Newspapers: Leftist Newspapers and Periodicals

2021 ◽  
Vol 23 (2) ◽  
pp. 34-37
Author(s):  
Thomas J. Beck
Keyword(s):  
Twentieth Century ◽  
Price Information ◽  
Social Democrats ◽  
Search Function ◽  
Advanced Search ◽  
Definition Of ◽  
The Cost ◽  
Pdf Format ◽  
Database Content ◽  
Insight Into

ProQuest Historical Newspapers: Leftist Newspapers and Periodicals is a source for leftist publications (mostly newspapers), largely published in the twentieth century. Here, the user can access articles in PDF format from 156 national and international publications. Navigating this database and the documents therein can be easily done, but articles cannot be magnified or reduced, which may prove problematic with PDFs of old newspapers. Database content can be found through browsing or by using a basic and/or advanced search. The browse and basic search options here are understandable, but the advanced search is not self-explanatory and can possibly confuse the user. As a consequence, a new user of this database will probably benefit from instruction in its use from either the vendor or someone else familiar with this resource. However, when this search function is used properly it can produce numerous, on-point results for any query. The same is true of the basic search and browsing features, though they tend to produce larger lists of results that are less on-point than the advanced search. The vendor did not provide specific price information for this review, only indicating that pricing is determined by an institution's size and number of users. As this provides potential subscribers with very little insight into the cost of acquiring this resource, its advised that they contact ProQuest for a price quote tailored to their own institution. Its licensing agreement is the same as those used for all ProQuest databases and is average in its composition (though somewhat longer than average). The quality and quantity of content in this resource is notable, and it will certainly be of use to those looking for articles from leftist newspapers and periodicals. However, the definition of “leftist” here may be problematic for some users! Communist and Socialist publications are certainly available in this database, but those for Anarchists, Social Democrats, and other leftists are not.

Abstract 77: Balancing Risks and Benefits of Anticoagulation Therapy in Atrial Fibrillation in Community Practice: Results from the ORBIT-AF Registry

2012 ◽  
Vol 5 (suppl_1) ◽  
Author(s):  
Michael W Cullen ◽  
Sunghee Kim ◽  
Jonathan P Piccini ◽  
Alan S Go ◽  
Gregg C Fonarow ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Stroke Risk ◽  
Anticoagulation Therapy ◽  
Bleeding Risk ◽  
Community Practice ◽  
Chads2 Score ◽  
Risk Patients ◽  
Study Population ◽  
Risk Treatment ◽  
The Cost

Background Oral anticoagulation (OAC) can reduce stroke risk at the cost of increased bleeding risk in those with atrial fibrillation (AF). Observational data have shown that higher-risk patients with AF most likely to benefit from OAC are less likely to receive OAC at hospital discharge. Methods We used data from ORBIT-AF Registry, a cohort of 9,589 AF patients enrolled among 173 participating outpatient practices. OAC was defined as warfarin or dabigatran use at study enrollment. Stroke and bleeding risk were calculated using the CHADS2 and ATRIA scores, respectively. Results The study population had a mean age of 73.5 years; 57.8% were men. Overall, 76.4% of patients received OAC. Use of OAC rose with increasing CHADS2 stroke risk, from 67% for CHADS2 <1 to 80% for CHADS2 ≥2 (p<0.0001). OAC use fell slightly with increasing ATRIA bleeding risk, from 77% for ATRIA score ≤3 to 74% with ≥5 (p=0.002 for trend). Among patients with low bleeding risk, rates of OAC increased commensurate with stroke risk (p<0.0001 for interaction; see figure). Higher bleeding risk tended to decrease rates of OAC among patients with a CHADS2 score ≥2 (p=0.13 for interaction). Conclusions In community-based outpatients with AF, use of OAC rose with increasing thromboembolic risk and declined with higher bleeding risk. These findings suggest that the risk-treatment paradox may be less that previously reported. Provision of OAC in community practice appears to appropriately consider patients' stroke and bleeding risks. Further research is required to understand how quality improvement initiatives can further improve stroke prevention.

Plan, Projection, Policy—Mathematical Programming and Planning Theory

1974 ◽  
Vol 6 (4) ◽  
pp. 419-429 ◽  
Author(s):  
L D Hopkins
Keyword(s):  
Optimal Choice ◽  
Planning Theory ◽  
Public Agency ◽  
Indirect Determination ◽  
Mathematical Programs ◽  
Planning Models ◽  
Definition Of ◽  
The Individual ◽  
The Cost ◽  
Programming Analysis

The purpose of planning models is to help determine how best to change the controllable variables of a system so that the system will move toward desired goals. In the case of public planning, the welfare criterion or planning objective is not likely to be the same as the objective function driving the behavior of the individual elements of the system. A rigorous definition of a theory of planning is provided through extensions to the linear-programming analysis of the decentralized firm in order to handle (1) the distinction between the planning objectives and behavioral objectives, and (2) the indirect determination of prices by a public agency through policies which modify existing prices sufficiently to achieve a prescribed allocation of resources. A set of three related mathematical programs is identified which yield respectively a target plan, a projection, and an optimal choice of policies. A combination of these programs defines the best solution in terms of the value of the target plan minus the cost of altering the system to achieve that target.

scholarly journals New Perspectives on Dystonia

2003 ◽  
Vol 30 (S1) ◽  
pp. S34-S44 ◽  
Author(s):  
Mélanie Langlois ◽  
Francois Richer ◽  
Sylvain Chouinard
Keyword(s):  
Age Of Onset ◽  
Clinical Investigation ◽  
Genetic Data ◽  
Therapeutic Agents ◽  
Anatomical Distribution ◽  
Beneficial Effects ◽  
Physiological Abnormalities ◽  
Primary Torsion ◽  
Primary Torsion Dystonia ◽  
Deep Brain

Dystonia is a syndrome of sustained muscular contractions with numerous underlying etiologies. This review examines the varied phenomenology of dystonias, its evolving classification including recent genetic data as well as its clinical investigation and treatment. Although age of onset, anatomical distribution and family history are key elements of the investigation of dystonia, classification increasingly relies on etiologic and genetic criteria. Physiological abnormalities in striatocortical circuits are common in dystonia but the pathophysiology is still unclear. In recent years, a great deal has been learned on the more common primary dystonias such as primary torsion dystonia and on dystonia-plus syndromes such as dopamine responsive dystonia. Treatment of dystonia has also evolved and there are now a number of therapeutic agents with clear beneficial effects including anticholinergics, benzodiazepines, and botulinum toxin and there is growing interest in neurofunctional surgery including deep brain stimulation.

scholarly journals The Impact of CEOs' Compensations on Cost Stickiness in Industrial Companies Listed on the Amman Stock Exchange

2021 ◽  
Vol 15 (1) ◽  
pp. 152
Author(s):  
Lina Fuad Hussien
Keyword(s):  
Stock Exchange ◽  
Industrial Companies ◽  
Level Of Activity ◽  
Cost Behavior ◽  
Study Population ◽  
The Difference ◽  
High Level ◽  
The Cost ◽  
The Impact ◽  
Cost Stickiness

The purpose of this study is to analyze the asymmetry in cost behavior (cost stickiness) and to identify the impact of CEOs&#39; compensation on the degree of cost stickiness behavior. The study population consists of the public shareholding companies listed on the ASE, which number (56) industrial company. Data were collected from (35) industrial companies for the period (2009 - 2019). To measure the degree of costs stickiness, The Model of Weiss (2010) was used. The Model of Weiss (2010) takes into account the costs and changes in the level of activity (sales) for the last four quarters of the company, Weiss (2010) model constructs the difference in logarithmic ratios of changes in cost. The study found that the CEO&#39;s compensation in Jordanian industrial companies consists of two forms. The companies pay fixed salaries or performance-related bonuses. The study found that the form of compensation that is paid to the CEO affects the behavior of managers. The results indicated that the performance-related rewards are accompanied by a decrease in the level of cost stickiness, and the compensation paid in the form of fixed salaries are accompanied by a high level of cost stickiness. The study recommends that companies should understand the role of the compensation form in administrative decisions, especially with regard to resource modifications, as management motives in relation to resource modifications must be taken into account because of their clear and direct impact on the cost structure of companies.

scholarly journals The level of satisfaction among orthodontic removable appliances patients

2012 ◽  
Vol 24 (3) ◽  
Author(s):  
Fatin Nadhirah Kamaludin Latifi ◽  
Ida Ayu Evangelina ◽  
Sri Susilawati
Keyword(s):  
Quality Of Life ◽  
Total Sample ◽  
Community Satisfaction ◽  
Satisfaction Index ◽  
Level Of Satisfaction ◽  
Study Population ◽  
Definition Of ◽  
Removable Appliances ◽  
Over Time

Introduction: Patient satisfaction is like many other psychological concepts, it is easy to understand but hard to define. The concept of satisfaction overlaps with similar themes such as happiness, contentment, and quality of life. Satisfaction is not some pre-existing phenomenon waiting to be measured, but a judgment that people form over time as they reflect on their experience. A simple and practical definition of satisfaction would be the degree to which desired goals have been achieved. Methods: The type of this research is descriptive with survey methode. Data is collected through questionnaire with the total sample of 150 respondents. The study population was based on accidental sampling, by which the sample was selected depending on who came to Orthodontic Department of RSGM FKG UNPAD, Bandung by the researcher during the period of the research. Results: The data is then analyzed using Community Satisfaction Index (Indeks Kepuasan Masyarakat) or IKM that which shows that 13 out of 14 indicators are still in B grade and overall IKM value of 7.90%, which means that the level of satisfaction has yet not met the expectation among removable appliances patients in Orthodontic Department of RSGM FKG UNPAD, Bandung. Conclusion: The level of satisfaction among removable appliances patients 0rthodontic are still have not met the patients’ expectation.

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