The Association between Depressive State and Maternal Cognitive Function in Postpartum Women

Objective Maternal amnesia is a transitional cognitive impairment occurring during pregnancy and the postpartum period. We evaluated the prevalence and extent of this suggested cognitive decline and the role of postpartum depression. Study Design A cross-sectional study was performed in women during the immediate postpartum period. Eligible women completed the Edinburgh Postnatal Depression Scale (EPDS). Cognitive function was assessed using an objective neurocognitive test (Symbol Digit Modalities Test, SDMT90, and SDMT4) and a subjective self-estimation questionnaire (Attention Function Index [AFI]). Results A total of 120 women completed the study questionnaires; 33.3% (40 women) exhibited signs of postpartum depression (EPDS ≥10). The subjective AFI test results correlated with the objective SDMT90 test results (r 2 = 0.2, p = 0.039). Depressed mothers scored significantly lower in the subjective AFI test (67.69 ± 12.01 in the study vs. 79.05 ± 14.3 in the comparison group; p < 0.001) and nearly significantly lower in the objective SDMT test (p = 0.057). In the multi-variable model, maternal depression was independently associated with the subjective AFI score (β = −13.7; 95% confidence interval [CI]: −19.1 to −8.2, p < 0.001) but not with the objective SDMT score (β = −3.48; 95% CI −8.3 to 1.3, p = 0.15), while controlling for maternal age, gestational age, and ethnicity. Conclusion Postpartum depression is common and appears to predominantly affect maternal self-assessment of cognitive ability, rather than a true cognitive impairment.

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Physiological Levels of Melatonin Relate to Cognitive Function and Depressive Symptoms: The HEIJO-KYO Cohort

The Journal of Clinical Endocrinology & Metabolism ◽

10.1210/jc.2015-1859 ◽

2015 ◽

Vol 100 (8) ◽

pp. 3090-3096 ◽

Cited By ~ 23

Author(s):

Kenji Obayashi ◽

Keigo Saeki ◽

Junko Iwamoto ◽

Nobuhiro Tone ◽

Kunihiko Tanaka ◽

...

Keyword(s):

Cognitive Impairment ◽

Depressive Symptoms ◽

Cognitive Function ◽

Confidence Interval ◽

Depressed Mood ◽

Geriatric Depression Scale ◽

Depression Scale ◽

Cross Sectional Study ◽

Community Dwelling ◽

Cross Sectional

Context: In contrast with randomized controlled trials, observational studies have suggested that physiological levels of melatonin are reduced in patients with dementia or depression, but the relationship has not been evaluated in large populations. Objective: The objective was to determine the relationships between physiological levels of melatonin and cognitive function and depressive symptoms. Design and Participants: A cohort of 1105 community-dwelling elderly individuals was enrolled in this cross-sectional study (mean age, 71.8 ± 7.1 y). Measures: Urinary 6-sulfatoxymelatonin excretion (UME) and Mini-Mental State Examination (MMSE; n = 935) and Geriatric Depression Scale (GDS; n = 1097) scores were measured as indices of physiological melatonin levels, cognitive function, and depressive symptoms, respectively. Results: With increases in UME quartiles, the prevalence of cognitive impairment (MMSE score ≤ 26) and depressed mood (GDS score ≥ 6) significantly decreased (P for trend = .003 and .012, respectively). In multivariate logistic regression models, after adjusting for confounders such as age, gender, socioeconomic status, physical activity, and sleep/wake cycles, higher UME levels were significantly associated with lower odds ratios (ORs) for cognitive impairment and depressed mood (ORs: Q1 = 1.00; Q2 = 0.88 and 0.76; Q3 = 0.66 and 0.85; Q4 = 0.67 and 0.53; P for trend = .023 and .033, respectively). In addition, the highest UME group showed a significantly lower OR for depressed mood than the lowest UME group (Q4 vs Q1: OR, 0.53; 95% confidence interval, 0.32–0.89; P = .033). UME levels above the median value were significantly associated with a lower OR for cognitive impairment, even after further adjustment for depressive symptoms (OR = 0.74; 95% confidence interval, 0.55–0.99; P = .043). Conclusions: Significant associations of higher physiological melatonin levels with lower prevalence of cognitive impairment and depressed mood were revealed in a large general elderly population. The association between physiological melatonin levels and cognitive function was independent of depressive symptoms.

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Is there a relationship between gestational diabetes and postpartum depression?

Current Women s Health Reviews ◽

10.2174/1573404816999200918115133 ◽

2020 ◽

Vol 16 ◽

Author(s):

Salman Khazaei ◽

Erfan Ayubi ◽

Saeid Bashirian ◽

Ronak Hamzehei ◽

Ensiyeh Jenabi

Keyword(s):

Gestational Diabetes ◽

Postpartum Depression ◽

Odds Ratio ◽

Depression Scale ◽

Binary Logistic Regression ◽

Cross Sectional Study ◽

University Education ◽

P Value ◽

Cross Sectional ◽

The Relationship

Background: The relationship between gestational diabetes and postpartum depression (PPD) is poorly understood and seldom studied. Objective: In an effort to explore this issue, the present study investigated the relationship between gestational diabetes and PPD. Methods: The present cross-sectional study was performed with 342 women who were referred to four urban health centers of Hamadan city, west of Iran. We used convenience sampling as a method to recruit women in each health center. We used a researcher-made checklist for gathering data on socio-demographic characteristics and potential risk factors of PPD. The Persian validated version of the Edinburgh Postnatal Depression Scale (EPDS) was used to assess PPD. Univariate and multivariable binary logistic regression was applied to estimate the odds ratio (OR) (95% confidence interval [CI]). Results: Gestational diabetes was identified as the most important risk factor for PPD with OR (95% CI) of 2.19 (1.11, 4.31); P-value=0.02 after adjusting for other variables. Moreover, the adjusted odds ratio showed that PPD among lesseducated women (primary school) was 3.5 times higher compared to women with a university education (OR=3.54, 95% CI: 1.27, 9.84; P-value=0.01). Conclusion: Our findings suggested that PPD is more likely among women with gestational diabetes and those who were less educated. Interventional and educational activities for reducing the risk of PPD can be targeted for use with this population.

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A focus on postpartum depression among Jordanian mothers

International Journal of Social Psychiatry ◽

10.1177/00207640211000100 ◽

2021 ◽

pp. 002076402110001

Author(s):

Esra’ O Taybeh

Keyword(s):

Social Support ◽

Postpartum Depression ◽

Marital Conflict ◽

Multivariate Logistic Regression Analysis ◽

Depression Scale ◽

Negative Attitude ◽

Cross Sectional Study ◽

Cross Sectional ◽

Web Based ◽

Unplanned Pregnancies

Background: The magnitude of postpartum depression in Jordan is under documented, and little is known about its potential sociodemographic and clinical correlates. Purpose: The aim of this study was to explore the prevalence and risk factors associated with postpartum depression among Jordanian mothers in the first 18 months after delivery. Method: This descriptive cross-sectional study was carried out from April to June 2020 in Jordan. A web-based survey was used for recruiting eligible participants. An Arabic version of the validated self-administered Edinburgh Postnatal Depression Scale questionnaire was used to measure postpartum depression with a cut-off score of ⩾12 which indicates probable depression. Results: A total of 1,071 Jordanian women participated in the study. Of those, 567 women had postpartum depression (52.9%). Multivariate logistic regression analysis revealed that postpartum depression was significantly associated with marital conflict (OR: 4.91; 95% CI: 2.36–10.20), negative attitude from the pregnancy (OR: 0.67; 95% CI: 0.45–0.99), unplanned pregnancies (OR: 1.73; 95% CI: 1.16–2.60), lack of social support (OR: 1.93; 95% CI: 1.12–3.32), time from last delivery (OR: 0.99; 95% CI: 0.98–1.00), insomnia (OR: 0.53; 95% CI: 0.35–0.82), and depression during the pregnancy (OR: 0.51; 95% CI: 0.33–0.78). Most of the participants (65.7%) sought social support to avoid, reduce, or treat postpartum depression. Conclusions: Postpartum depression among Jordanian women was the highest in comparison to that of women in other countries in the region. Therefore, screening for the presence of depressive symptoms should be implemented during regular pregnancy care visits. Social support should be encouraged in order to avoid, reduce, or treat postpartum depression.

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Fine or Gross Motor Index as a Simple Tool for Predicting Cognitive Impairment in Elderly People: Findings from The Irish Longitudinal Study on Ageing (TILDA)

Journal of Alzheimer s Disease ◽

10.3233/jad-210704 ◽

2021 ◽

pp. 1-8

Author(s):

Xiao Liu ◽

Ayiguli Abudukeremu ◽

Yuan Jiang ◽

Zhengyu Cao ◽

Maoxiong Wu ◽

...

Keyword(s):

Cohort Study ◽

Cognitive Impairment ◽

Longitudinal Study ◽

Cognitive Function ◽

Prospective Cohort Study ◽

Prospective Cohort ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Simple Tool

Background: Several kinds of motor dysfunction can predict future cognitive impairment in elderly individuals. However, the ability of the fine motor index (FINEA) and gross motor index (GROSSA) to predict the risk of cognitive impairment has not been assessed. Objective: We investigated the associations between FINEA/GROSSA and cognitive impairment. Methods: The data of 4,745 participants from The Irish Longitudinal Study on Ageing (TILDA) were analyzed. Cognitive function was assessed using the Mini-Mental State Examination (MMSE). We first assessed the correlation between the FINEA GROSSA and MMSE in a cross-sectional study. Then, we further investigated the predictive role of the incidence of cognitive impairment in a prospective cohort study. Results: We found that both FINEA and GROSSA were negatively correlated with MMSE in both the unadjusted (FINEA: B = –1.00, 95%confidence intervals (CI): –1.17, –0.83, t = –11.53, p < 0.001; GROSSA: B = –0.85, 95%CI: –0.94, –0.76, t = –18.29, p < 0.001) and adjusted (FINEA: B = –0.63, 95%CI: –0.79, –0.47, t = –7.77, p < 0.001; GROSSA: B = –0.57, 95%CI: –0.66, –0.48, t = –12.61, p < 0.001) analyses in a cross-sectional study. In a prospective cohort study, both high FINEA and high GROSSA were associated with an increased incidence of cognitive function impairment (FINEA: adjusted odds ratios (OR) = 2.35, 95%CI: 1.05, 5.23, p = 0.036; GROSSA adjusted OR = 3.00, 95%CI: 1.49, 6.03, p = 0.002) after 2 years of follow-up. Conclusion: Higher FINEA and GROSSA scores were both associated with an increased incidence of cognitive impairment. FINEA or GROSSA might be a simple tool for identifying patients with cognitive impairment.

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Faktor Prediktor Terjadinya Depresi Postpartum di Rumah Sakit Panti Rapih Yogyakarta

I Care Jurnal Keperawatan STIKes Panti Rapih ◽

10.46668/jurkes.v1i1.39 ◽

2020 ◽

Vol 1 (1) ◽

pp. 61-70

Author(s):

Agnes Mahayanti ◽

Intansari Nurjannah ◽

Widyawati

Keyword(s):

Marital Satisfaction ◽

Postpartum Depression ◽

Postpartum Period ◽

Statistical Tests ◽

Depression Scale ◽

Sampling Technique ◽

Psychological Adaptation ◽

Bivariate Analysis ◽

Cross Sectional ◽

Postpartum Blues

Background: The postpartum period was a physical and psychological adaptation process. Psychological disturbances could present in form of postpartum blues, postpartum depression, and postpartum psychosis. Objective: The objective of this research was to determine the incidence of postpartum depression, identify predictors of postpartum depression and identify the dominant predictors of postpartum depression. Methods: this research used a cross sectional design. Sample were pregnant women which were chosen by random sampling technique. Data was collected with questionnaire to measure the predictors of postpartum depression was carried out with the Revision Postpartum Depression Predictors Inventory (PDPI) questionnaire and to measure depression scores used with the Edinburgh Postnatal Depression Scale (EPDS). Data analysis was done by univariate and bivariate analysis with with chi-square statistical tests and multivariate with logistic regression tests. Results: The results showed that the significant predictors were economic status, self-esteem, marital satisfaction, postpartum blues, and prenatal depression. The dominant predictor factor is satisfaction in marriage with a t value of 2.778 times. Conclusion: The results of the study show that marital satisfaction is a dominant predictor of postpartum depression, indicating that marital satisfaction or relationship quality is one of the important support systems because of the need for partner involvement in care actions during the pregnancy period until with the puerperium as efforts to prevent postpartum depression. Keywords: postpartum depression, postpartum period, postpartum bues

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Relationship between postpartum depression and lactation status at a Japanese perinatal center: A cross-sectional study

F1000Research ◽

10.12688/f1000research.20704.2 ◽

2020 ◽

Vol 8 ◽

pp. 1845 ◽

Cited By ~ 1

Author(s):

Shunji Suzuki

Keyword(s):

Postpartum Depression ◽

Exclusive Breastfeeding ◽

Edinburgh Postnatal Depression Scale ◽

Depression Scale ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Face To Face ◽

Perinatal Center ◽

Feeding Methods

Background: Some studies have demonstrated that breastfeeding can protect mothers from postpartum depression; therefore, we examined the association between postpartum depression and lactation status at one month after delivery at a Japanese perinatal center. Methods: We reviewed the obstetric records of all (total 809) nulliparous healthy women with vaginal singleton delivery at 37-41 weeks’ gestation at our institute between July 2018 and June 2019. A face-to-face interview with the women was conducted on admission for delivery to ask whether or not they hoped to perform exclusive breastfeeding for their babies, and an additional interview was conducted one month after delivery to ask about their feeding methods currently. Maternal mental status was examined based on the scores using the Edinburgh Postnatal Depression Scale (EPDS), and women with EPDS scores of ≥9 points were regarded as ‘positive screening’. Results: 592 women (73.1%) hoped to perform exclusive breastfeeding for their babies on admission. Of these, at one month, 442 (74.7%) performed exclusive breastfeeding, while 150 (25.3%) performed mixed or artificial feeding. The average EPDS scores and the incidence of EPDS scores ≥9 points in the women performing exclusive breastfeeding were 4.3 ± 3.6 and 14.3% (63/442), respectively. They did not differ from those in the women performing mixed or artificial breast feeding [4.2 ± 3.7, p = 0.60 and 13.3% (20/150), p = 0.78]. Conclusion: Development of postpartum depression does not seem to be associated with incomplete breastfeeding at our hospital, and therefore there are other risk factors indicated in the development of postpartum depression.

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Differential associations between depression and cognitive function in MCI and AD: a cross-sectional study

International Psychogeriatrics ◽

10.1017/s1041610218001527 ◽

2019 ◽

Vol 31 (08) ◽

pp. 1151-1158 ◽

Cited By ~ 3

Author(s):

Chang Hyun Lee ◽

Do Hoon Kim ◽

Yoo Sun Moon

Keyword(s):

Executive Function ◽

Cognitive Function ◽

Geriatric Depression Scale ◽

Depression Scale ◽

Cross Sectional Study ◽

Cross Sectional ◽

Neuropsychological Screening ◽

Screening Battery ◽

Clinical Research Center ◽

Sectional Analysis

ABSTRACTObjective:Despite the possibility that cognitive deficits associated with depression may have different patterns depending on the level of neurocognitive impairment, there remains no clear evidence of this. This study aimed to investigate the differential association between depression and cognitive function in patients with mild cognitive impairment (MCI) and Alzheimer’s disease (AD).Methods:A cross-sectional analysis was performed of data from 1,724 patients with MCI and 1,247 patients with AD from the Clinical Research Center for Dementia in Korea. Depression was assessed using the Korean form of the Geriatric Depression Scale, and cognition was measured using the Seoul Neuropsychological Screening Battery, which includes five domains (attention, language and related function, visuospatial function, memory, and frontal/executive function).Results:Significant differences were found between the two groups (non-depressed vs. depressed) in visuospatial, memory, and executive function domains in the MCI group, as well as in the attention domain in the AD group. The association between depressive symptoms and cognitive function was significantly greater in patients with MCI than in those with AD. These associations were more pronounced in memory and executive function.Conclusion:Our findings suggest that the association between depression and decreased cognitive function is more pronounced in MCI than AD.

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Increased Psychopathology and Maladaptive Personality Traits, But Normal Cognitive Functioning, In Patients after Long-Term Cure of Acromegaly

Endocrine Reviews ◽

10.1210/edrv.31.5.9993 ◽

2010 ◽

Vol 31 (5) ◽

pp. 778-779

Author(s):

Jitske Tiemensma ◽

Nienke R. Biermasz ◽

Roos C. van der Mast ◽

Moniek J. E. Wassenaar ◽

Huub A. M. Middelkoop ◽

...

Keyword(s):

Cognitive Function ◽

Personality Traits ◽

Cognitive Dysfunction ◽

Short Form ◽

Depression Scale ◽

Cross Sectional Study ◽

Cross Sectional ◽

Personality Changes ◽

Irreversible Effects

ABSTRACT Objective Active acromegaly is associated with psychopathology, personality changes, and cognitive dysfunction. It is unknown whether, and to what extent, these effects are present after long-term cure of acromegaly. Aim The aim of the study was to assess psychopathology, personality traits, and cognitive function in patients after long-term cure of acromegaly. Design This was a cross-sectional study. Patients and Methods We studied 68 patients after long-term cure (13 ± 1 yr) of acromegaly and 68 matched controls. We compared these data with 60 patients treated for nonfunctioning pituitary macroadenomas (NFMAs) and 60 matched controls. Psychopathology was assessed using the Apathy Scale, Irritability Scale, Hospital Anxiety and Depression Scale, and Mood and Anxiety Symptoms Questionnaire short-form and personality by the Dimensional Assessment of Personality Pathology short-form (DAPP). Cognitive function was assessed by 11 tests. Results Compared with matched controls, patients cured from acromegaly scored significantly worse on virtually all psychopathology questionnaires and on several subscales of the DAPP. Compared with NFMA patients, patients cured from acromegaly scored worse on negative affect (P = 0.050) and somatic arousal (P = 0.009) and seven of 18 subscales of the DAPP (P < 0.05). Cognitive function in patients cured from acromegaly did not differ from matched controls or patients treated for NFMA. Conclusion Patients with long-term cure of acromegaly show a higher prevalence of psychopathology and maladaptive personality traits but not cognitive dysfunction, compared with matched controls and patients treated for NFMA. These results suggest irreversible effects of previous GH excess, rather than effects of pituitary adenomas per se and/or their treatment, on the central nervous system.

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Prevalence and risk factors of postpartum depression

European Psychiatry ◽

10.1016/j.eurpsy.2017.02.360 ◽

2017 ◽

Vol 41 (S1) ◽

pp. S362-S362 ◽

Cited By ~ 1

Author(s):

R. F Cherif ◽

I. Feki ◽

R. Sellami ◽

D. Trigui ◽

I. Baâti ◽

...

Keyword(s):

Risk Factors ◽

Postpartum Depression ◽

Depression Scale ◽

Total Sample ◽

Cross Sectional Study ◽

School Level ◽

Cross Sectional ◽

Competing Interest ◽

Associated Risk Factors ◽

Almost All

IntroductionChildbirth represents for women a time of vulnerability to postpartum mood disorders. These disorders range in severity from the early maternal blues to postpartum psychosis. Along this spectrum is postpartum depression (PPD) that may have many risk factors.ObjectivesThe study aims to examine the prevalence of PPD and associated risk factors among a sample of Tunisian women receiving cares in the hospital of Sfax.MethodsThis is a descriptive cross-sectional study regarding 150 parturients examined during the first and the sixth week post-delivery. The EPDS (Edinburgh postnatal depression scale) was used to assess PPD.ResultsThe total sample had a mean age of 29.61 years. During the sixth week study period, 126 of 150 were examined. Almost all of the women have a low school level (82.7%). Only 9.3% had a personal psychiatric history. Multiparity was found in 43.3% of cases. The current pregnancy was undesired in 15.3% of cases. Sympathetic signs of pregnancy were reported by 64.7% of women. The prevalence of PPD in the first week was 14.7% and 19.8% in the sixth week after delivery. The PPD was associated with the maternal age (> 35 years), the low school level, the existence of mood personal background, the parity, the difficulty to accept the pregnancy and sympathetic signs of pregnancy.ConclusionPostpartum depression is common on our sample. Identifying risk factors of PPD allows clinicians to detect subgroups of women with an increased vulnerability who might receive early psychiatric care.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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Prevalence of Postpartum Depression Among Lactating Mothers of Infant Twins and Singletons in Igboora, Oyo State, Nigeria

Current Developments in Nutrition ◽

10.1093/cdn/nzab046_071 ◽

2021 ◽

Vol 5 (Supplement_2) ◽

pp. 774-774

Author(s):

Oluwatosin Leshi ◽

Christianna Rotimi-Williams ◽

Olajumoke Leshi

Keyword(s):

Postpartum Depression ◽

Depression Scale ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Funding Sources ◽

Breastfeeding Practices ◽

Lactating Mothers ◽

The Mean ◽

Source Of Information

Abstract Objectives The objective to assess the prevalence of postpartum depression among lactating mothers of infant twins and singletons in Igboora, Oyo state, Nigeria. Methods The cross-sectional study was carried out in Igboora, a twinning community in south western Nigeria. Snowballing technique was used to reach 85 and 90 mothers of twins and singletons respectively. Interview based questionnaires were administered to the mothers to assess their breastfeeding practices and Edingburgh Postpartum Depression Scale was used to assess depression. Analysis was done using IBM-SPSS version 21.0. Student T-test was be used to compare the mean score of postpartum depression for single mothers and twin mothers at p < 0.05. Results About 6 out of every ten respondents (55.6% for singleton; 64.7% for twins) had received previous education on breastfeeding and the main major source of information was hospital settings (55.6% for mothers of singletons and 61.2% for twin mothers). Twenty-seven and 36.5% of mothers of singletons and twins respectively indicated to have received adequate support from their spouses and mothers-in-law. Less than half (44.8% singletons; 44.7% twins) of the mothers-initiated breastfeeding within one hour of birth while majority of the mothers (94.4% for singletons and 83.5% for twins) introduced colostrum to their babies, just about half; 51.1% and 55.3% of the mothers of singletons and twins respectively introduced prelacteal feed to their children. Overall, breastfeeding was found to be better practiced among mothers of singletons than mothers of twins with less than half (48.2%) of the mothers reporting good breastfeeding practices while about two-thirds (64.4%) of the mothers of singletons had good breastfeeding practices. Mothers of singletons were more depressed than the mothers of twins (21.1% and 11.8% respectively). However, no significant association was observed between postpartum depression and breastfeeding practices among both the mothers of singletons and twins in this study. Conclusions Increased prevalence of postpartum depression was recorded among the respondents, mothers of singletons are more likely to have postpartum depression than mothers of twins. Funding Sources There was no funding for this study.

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