3-(2-Isocyanoethyl)indole: A Versatile Reagent for Polycyclic Spiroindoline Synthesis
Keyword(s):
The Past
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Polycyclic spiroindolines are the basic skeletons of large families of indole alkaloids that exhibit a broad spectrum of biological and pharmacological activities. The past seven years have seen impressive developments in the construction of polycyclic spiroindolines enabled by 3-(2-isocyanoethyl)indole-based cascade reactions. We herein give a brief summary on this evolution and highlight our contributions in this field.1 Introduction2 Cascade Reactions Involving Nitrilium Ion Intermediates3 Cascade Reactions Involving Ketenimine Intermediates4 Conclusion and Outlook
2020 ◽
Vol 23
(26)
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pp. 2945-2959
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2020 ◽
Vol 17
(5)
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pp. 496-517
2020 ◽
Vol 16
(4)
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pp. 454-486
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2011 ◽
Vol 112
(2)
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pp. 188-193
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2021 ◽
Vol 68
(2)
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