scholarly journals A Retrospective Study of Factors Affecting Pathway and Time to Diagnosis, Time to Treatment in Children with Cancer in a Single Center in South India

2021 ◽  
Vol 42 (03) ◽  
pp. 247-254
Author(s):  
Harsha Prasada Lashkari ◽  
Shobha Prasada ◽  
Jayatheerth Joshi ◽  
Sadashiva Rao

Abstract Introduction The overall cure rate of childhood cancers is above 79% in the developed world, whereas in the developing world, like in India, it is around 50%. It is vital to know the routes of presentation and factors affecting the presentation of childhood cancers in primary, secondary, and tertiary care to design a better survival strategy in childhood cancer. Objective The aim of this study was to know the factors affecting the time to diagnosis and time to treatment in children with cancers in a single center in South India. Materials and Methods It was a retrospective cohort study of children diagnosed with cancer between January 1, 2014 and December 31, 2016 at the pediatric oncology unit, KMC Hospital Mangalore, India. The patient interval, time to diagnosis, patient's family, economic background, parental education, and referral pattern were recorded, and its impact on the time taken to diagnosis was studied. The data was analyzed using SPSS 20.0 software. Results Out of 111 children, 72 were boys (64.8%). Fifty-one (46%) children belonged to the less than 5-year age group. The most common cancer was acute lymphoblastic leukemia, diagnosed in 50% (56/111) children, followed by acute myeloid leukemia in 14/111(12.6%), brain tumors in 9 (8.1%), and neuroblastoma in 10 (9%) children. The median patient interval/patient delay was 14 days (1–90 days), referral interval was 14 days (1–150 days), and overall time to diagnosis was 41 days (1–194 days). The first contact was the pediatrician in 86/111 (77.4%). Sixty-four percent (71/111) referral came from a secondary care hospital, and the remaining from the outpatient clinics. There was no difference in sex and patient interval (p = 0.278) and overall time to diagnosis (p = 0.4169), age (p = 0.041), mother’s education (p = 0.034), and type of cancer (p = 0.013) were three critical factors that determined the time to diagnosis. Conclusion Majority of the children diagnosed with cancer presented via referral from pediatricians. An equal number of them were referred to as routine and emergency patients. Age, mother's education, and type of cancers were the crucial factors associated with the overall time taken to diagnosis.

2020 ◽  
Vol 48 (3) ◽  
Author(s):  
Revi Rosavika Kinansi ◽  
Tri Wurisastuti

Abstract Factors influencing development of child’s health include child's nutritional intake, heredity,, parenting patterns, the environment parental education, parent's work and history of infections. This study aims to determine the relationship between the history of malaria with the development of children aged 3659 months in eastern Indonesia based on Basic Health Research (Riskesdas) 2018. The sample were all children aged 36-59 months in eastern Indonesia which have normal nutrition. Data were analyzed using a backward elimination method of multiple logistic regression. Based on these results, factors affecting the development of children aged 36-59 months in 5 malaria endemic provinces are mother's education and children's residence either in rural or urban areas. Whereas the history of malaria infection factors do not have a significant effect on the development of children aged 36-59 months. Father's education and work status of parents were confounding variables on the development of children aged 36-59 months. A good mother's education provides an opportunity of 1,401 times to realize good development for children aged 36-59 months. Likewise with children who live in urban areas have a chance of 1,189 times have a good development compared with children aged 36-59 months who live in rural areas. Keywords: Development of children aged 36-59 months, history of malaria infection, education of both parents, work of both parents, domicile Abstrak Faktor-faktor yang mempengaruhi perkembangan antara lain, asupan nutrisi anak, hereditas (bawaan dari orang tua), pola asuh kedua orang tua, lingkungan dimana anak tinggal, pendidikan orang tua, pekerjaan orang tua dan riwayat infeksi pada anak. Penelitian ini bertujuan untuk mengetahui apakah terdapat hubungan antara riwayat penyakit malaria dengan perkembangan anak usia 36-59 bulan di wilayah timur Indonesia berdasarkan data Riset Dasar Kesehatan Tahun 2018. Sampel dalam analisis ini adalah seluruh anak berusia 36-59 bulan diwilayah Indonesia timur yang memiliki gizi normal. Data dianalisis menggunakan metode backward elimination regresi logistik berganda. Berdasarkan hasil penelitian, faktor yang berpengaruh terhadap perkembangan anak usia 36-59 bulan di 5 provinsi endemis malaria yaitu pendidikan ibu dan tempat tinggal anak baik di pedesaan atau di perkotaan. Sedangkan untuk faktor riwayat infeksi malaria tidak memiliki pengaruh yang signifikan terhadap perkembangan anak usia 36-59 bulan. Pendidikan ayah dan status bekerja orang tua merupakan variabel perancu terhadap perkembangan anak usia 36-59 bulan. Pendidikan ibu yang baik memberi peluang sebesar 1,401 kali dapat mewujudkan perkembangan yang baik untuk anak usia 36-59 bulan. Begitu pula dengan anak yang tinggal di perkotaan memiliki peluang sebesar 1,189 kali memiliki perkembangan yang baik dibandingkan dengan anak usia 36-59 bulan yang tinggal di perdesaan. Kata kunci: perkembangan anak, riwayat infeksi malaria, pendidikan, pekerjaan orang tua, tempat tinggal


2020 ◽  
Vol 11 (1) ◽  
pp. 1-9
Author(s):  
Hoirun Nisa

AbstrakLatar belakang: Remaja perempuan sering memiliki pengetahuan yang kurang mengenai kesehatan reproduksi termasuk menstruasi, dan masalah menstruasi dapat mempengaruhi kehadiran siswi di sekolah. Penelitian ini bertujuan untuk mengetahui faktor yang berhubungan dengan ketidakhadiran siswi sekolah dasar selama masa menstruasi.Metode: Penelitian cross-sectional dilakukan di sembilan sekolah dasar di Kota Tangerang Selatan. Informasi yang dikumpulkan antara lain karakteristik demografi, umur menarche, durasi menstruasi, dismenore, pengetahuan, dan sumber informasi mengenai menstruasi dari remaja siswi. Partisipan terdiri dari 133 siswi yang telah mengalami menstruasi. Uji chi-square dan regresi logistik digunakan dalam data analisis.Hasil: Frekuensi siswi yang tidak masuk sekolah saat menstruasi cukup tinggi (19%). Rata-rata ketidakhadiran sebanyak 2,4 hari setiap siklus menstruasi, dan alasan utama ketidakhadiran di sekolah antara lain takut tembus (69%), rasa sakit/tidak nyaman (62%), dan ejekan dari siswa laki-laki (19%). Pengetahuan yang buruk tentang menstruasi (AOR = 5,24; 95% CI = 1,69-16,30) dan dismenore (AOR = 6,05; 95% CI = 1,32-27,69) mempunyai hubungan positif yang signifikan dengan ketidakhadiran di sekolah (p<0,05), sementara pendidikan ibu secara signifikan dapat mencegah ketidakhadiran siswi pada masa menstruasi (p<0,05).Kesimpulan: Faktor-faktor yang mempengaruhi ketidakhadiran siswi di sekolah adalah pengetahuan tentang menstruasi, dismenore, dan status pendidikan ibu. Penelitian ini menunjukkan bahwa memberikan pengetahuan dan manajemen menstruasi dapat bermanfaat dalam mengurangi ketidakhadiran siswi akibat menstruasi di sekolah. Kata kunci: menstruasi, menarche, pengetahuan, ketidakhadiran di sekolah AbstractBackground: Adolescent girls often have limited knowledge regarding reproductive health including menstruation, and challenges associated with menstruation may affect girls’ school attendance. This study aimed to examine factors associated with school absence during menstruation among schoolgirls.Method: A cross-sectional study was conducted in nine elementary schools in the South Tangerang City. The information included the schoolgirls’ demographic background, menarche age, duration of menstrual, dysmenorrhea, knowledge about menstruation, and source of information related to menstruation. Participants were 133 schoolgirls who had experienced first menstruation. Chi-square test and logistic regression were used for data analysis.Results: The frequency of schoolgirls who missed school during menstruation was slightly high (19%). Absentee schoolgirls missed an average of 2.4 days each menstrual cycle, and main reasons for school absence were fear of leakage (69%), pain/discomfort (62%), and boys ridiculed (19%). Poor knowledge about menstruation (AOR = 5.24; 95 % CI = 1.69-16.30) and dysmenorrhea (AOR = 6.05; 95% CI: 1.32-27.69) revealed significant positive association with school absence during menstruation (p<0.05), while mother’s education had significantly prevented the schoolgirls from school absence during menstruation (p<0.05). Conclusion: Factors affecting school absence of schoolgirls included knowledge of menstruation, dysmenorrhea, and mother’s education status. The findings suggest that providing knowledge and menstrual management could benefit on reducing school absenteeism among schoolgirls due to menarche at school. Keywords: menstruation, menarche, knowledge, school absence


Author(s):  
C. P. Khuntia ◽  
S. K. Kar ◽  
B. Dwibedi

Background: Bacterial meningitis is a leading cause of high childhood transience. It is the foremost cause of fatality in pediatric age group of 0-5 years in India accounting 0.5 to 2.6% of hospital admissions with CFR 16-30%. Based on above scenario, the study was undertaken to address the prevalence, etiology, social determinants of health factors of bacterial meningitis among under five children Odisha, India. Methods: A cross sectional study comprising of children under five years of age admitted to tertiary care hospital and teaching institutions in Cuttack with suspected clinical diagnosis of bacterial meningitis during April, 2012 to September 2013. About 634 children enrolled into the study after getting appropriate consent from parents or their legal guardians. Lumbar puncture was done and CSF was sent for biochemical analysis, cell counts, staining, culture, latex agglutination test (LAT) and real time polymerase chain reaction (RT PCR). Results: About 61 children (10.4%) were confirmed with diagnosis of bacterial meningitis by either culture, latex or RT PCR.  Male children (74.7%) were significantly more prone to bacterial meningitis than females (24.3%). The common isolated pathogens were Streptococcus pneumonia, Haemophilus influenza type b, E. coli, Pseudomonas aeruginosa, Klebseilla pneumoniae and Staphylococcus aureus. Streptococcus pneumoniae was observed to be most common pathogen (57.6%) followed by Haemophilus influenzae type b (26.2%). The risk factors analyzed showed statistically significant association (p<0.01) with low household income, mother’s education, overcrowding (more than 3 persons in a single room), smoking and poor ventilation of household. Conclusion: Strengthening early detection of bacteria meningitis by rapid diagnostic test like LATEX, RT PCR and prompt treatment of emergent case at the household level, improvement in mother’s education and awareness, transportation to local hospital and facility for treatment and care should be utmost priority in the present scenario. It is crucial to assess the burden of bacterial meningitis with its etiology is in this region as  vaccines are yet to be introduced in the child vaccine program.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Agung Dwi Laksono ◽  
Ratna Dwi Wulandari ◽  
Mursyidul Ibad ◽  
Ina Kusrini

Abstract Background Even though the Indonesian government have set regulations for maintaining exclusive breastfeeding practices, the coverage remains low. The study aims to analyze the effects of mother’s education level on the coverage of exclusive breastfeeding in Indonesia. Methods This study used data from the 2017 Nutrition Status Monitoring Survey. It covered data of 53,528 children under 5 years old (7–59 months) as the samples. Variables included exclusive breastfeeding status, mother’s education level, mother’s age, marital status, employment status, gender, residence, under five’s age and gender. A binary logistics regression was performed in the final test. Results Mothers who graduated from elementary school were 1.167 times more likely to perform exclusive breastfeeding compared to mothers who never attended schools. Additionally, those who graduated from junior high school had 1.203 times possibilities to give exclusive breastfeeding compared to mothers without educational records. While, mothers who graduated from high school were 1.177 times more likely to perform exclusive breastfeeding compared to those without educational records. Mothers who graduated from tertiary education had 1.203 times more possibilities to perform exclusive breastfeeding compared to mothers who were never enrolled to schools. Other variables also became affecting predictors on exclusive breastfeeding, such as mother’s age, mother’s employment status, child’s age, and residence. Conclusions The mother’s education level positively affects exclusive breastfeeding practice in Indonesia.


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