Biological activities and chemical components of Potentilla kleiniana Wight & Arn

2019 ◽  
Vol 34 (22) ◽  
pp. 3262-3266
Author(s):  
Song Hua Xuan ◽  
In Ki Hong ◽  
Yun Ju Lee ◽  
Ji Woong Kim ◽  
Soo Nam Park
Molecules ◽  
2018 ◽  
Vol 23 (10) ◽  
pp. 2567 ◽  
Author(s):  
Muhammad Nisar ◽  
Junwei He ◽  
Arsalan Ahmed ◽  
Youxin Yang ◽  
Mingxi Li ◽  
...  

Medicinal plants have served humans since prehistoric times to treat various ailments. Both developed and underdeveloped countries rely on traditional systems of medication using natural sources from plants. Phyllanthus is one of the largest genus in the family Phyllanthaceae, comprising over 700 well known species cosmopolitan in distribution mainly in the tropics and subtropics. Phyllanthus species are being in constant used in traditional medications to cure an array of human diseases (constipation, inhalation related, arthritis, loss of appetite, injuries, conjunctivitis, diarrhoea, running nose, common cold, malaria, blennorrhagia, colic, diabetes mellitus, dysentery, indigestion, fever, gout, gonorrheal diseases of males and females, skin itching, jaundice, hepatic disorders, leucorrhea, vaginitis, menstrual irregularities, obesity, stomach pains, and tumors), confectionaries, food industry, and in some pesticides. Phyllanthus species are rich in diversity of phytochemicals e.g., tannins, terpenes, alkaloids, glycosidic compounds, saponins, and flavones etc. More in depth studies are a direly needed to identify more compounds with specific cellular functions to treat various ailments.


2019 ◽  
Vol 2019 ◽  
pp. 1-10 ◽  
Author(s):  
Ying Zhang ◽  
Yuewu Wang ◽  
Song Yang ◽  
Yunfeng Xiao ◽  
Haibin Guan ◽  
...  

As a well-known Chinese herb medicine, the Cistanche deserticola has been used for the treatment of kidney deficiency syndrome in China for thousands of years. Both the raw product of Cistanche deserticola slices (RCD) and its Wine Steam-Processed Product (WSCD) are used clinically for different effects. In this study, the influences of steaming process with wine (SPW) from Cistanche deserticola on chemical compositions and biological effects were investigated. The principal component analysis (PCA) and quantitative analysis were used to study the differences of the chemical compositions. The effects of nourishing kidney were also investigated to compare the differences between the RCD and the WSCD. The PCA results indicated that the obvious separation was achieved in the RCD and WSCD. The results of quantitative analysis showed that the WSCD has higher amounts of total polysaccharides, total PhGs, isoacteoside, and osmanthuside B than RCD, while the content of 2′-acetylacteoside and acteoside decreased after the SPW. The comparison of RCD and WSCD on biological activities showed that both could restore the level of sex hormone in the model of kidney-yang deficiency and improve the antioxidant effect. The WSCD were much better in increasing the viscera weight of kidney and seminal vesicle. The results indicated that SPW changed its chemical components and enhanced its biological activities.


2019 ◽  
Vol 22 (1) ◽  
pp. 73-81 ◽  
Author(s):  
Shuliang He ◽  
Dacheng Wang ◽  
Yamei Zhang ◽  
Shengxiang Yang ◽  
Xiang Li ◽  
...  

2020 ◽  
Vol 2020 ◽  
pp. 1-10
Author(s):  
Fan He ◽  
Chun-Xin Xiao ◽  
Can-Jian Wang ◽  
Jie Liang ◽  
Qi-Qing Cheng ◽  
...  

Nonalcoholic fatty liver disease (NAFLD) is a prevalent chronic liver disease. The Hugan Qingzhi formula (HGQZ) has been proven effective in treating NAFLD through clinical and pharmacological mechanism studies. A screening study of the chemical components was carried out to better control the quality of this formula. Current research has combined biological activity assessment with chemical analysis to screen and identify the bioactive compounds in HGQZ for use as potential quality markers (Q-markers) to control the quality of this herbal product. The HGQZ extracted by three different solvents was evaluated in a free fatty acid-induced hepatic steatosis LO2 cell model. Simultaneously, the twelve major chemical constituents of these extracts were quantitatively measured by ultrahigh-performance liquid chromatography coupled with triple quadrupole mass spectrometry (UHPLC-QQQ-MS/MS). Extraction with 50% ethanol showed the most potent lipid-lowering effect in steatosis LO2 cells and the highest extraction rate of major chemical constituents. Correlation analysis was used to establish the relationship between the biological activities and chemical characteristics of these extracts. The results showed that the contents of typhaneoside, hyperoside, isoquercitrin, isorhamnetin-3-O-neohesperidoside, notoginsenoside R1, and alisol B 23-acetate were positively correlated to the lipid-lowering effect. The subsequent bioassay confirmed that typhaneoside, isoquercitrin, and alisol B 23-acetate played the role of reducing the lipid effect. In conclusion, 50% of ethanol extraction produced the most active extract of HGQZ. Typhaneoside, isoquercitrin, and alisol B 23-acetate could be considered potential Q-markers for the quality control of HGQZ.


2020 ◽  
Vol 21 (14) ◽  
pp. 4986 ◽  
Author(s):  
Axelle Septembre-Malaterre ◽  
Mahary Lalarizo Rakoto ◽  
Claude Marodon ◽  
Yosra Bedoui ◽  
Jessica Nakab ◽  
...  

Traditional remedies have been used for thousand years for the prevention and treatment of infectious diseases, particularly in developing countries. Of growing interest, the plant Artemisia annua, known for its malarial properties, has been studied for its numerous biological activities including metabolic, anti-tumor, anti-microbial and immunomodulatory properties. Artemisia annua is very rich in secondary metabolites such as monoterpenes, sesquiterpenes and phenolic compounds, of which the biological properties have been extensively studied. The purpose of this review is to gather and describe the data concerning the main chemical components produced by Artemisia annua and to describe the state of the art about the biological activities reported for this plant and its compounds beyond malaria.


Medicines ◽  
2021 ◽  
Vol 8 (10) ◽  
pp. 58
Author(s):  
Amanda G. Smith ◽  
Victoria N. Miles ◽  
Deltrice T. Holmes ◽  
Xin Chen ◽  
Wei Lei

Arnica has traditionally been used in treating numerous medical conditions, including inflammation and pain. This review aims to summarize the results of studies testing Arnica products for pain management under different conditions, including post-operation, arthritis, low back pain, and other types of musculoskeletal pain. Based on data from clinical trials, Arnica extract or gel/cream containing Arnica extract shows promising effects for pain relief. These medical benefits of Arnica may be attributed to its chemical components, with demonstrated anti-inflammatory, antioxidant, anti-microbial, and other biological activities. In conclusion, Arnica could be an adjunct therapeutical approach for acute and chronic pain management.


2019 ◽  
Vol 3 (3) ◽  
Author(s):  
Yuchen Xiao ◽  
Yang Yang ◽  
Jianping Yong ◽  
Canzhong Lu

2020 ◽  
Vol 17 (2) ◽  
pp. 1
Author(s):  
Izzah Afifah Noh ◽  
Vivien Yi Mian Jong

Traditionally, Calophyllum genus was used for swollen gums, arthritis, diarrhea, chronic abscess, skin infections, and lesions treatment. C. ferrugineum from Sarawak has least studied about their phytochemical constituents and biological activities. The objectives are to isolate and characterize the chemical components from C. ferrugineum and to determine their antimicrobial and antioxidant activity. The plant stem barks were collected from National Park in Sarawak and underwent extraction process. The extracts underwent isolation and purification processes by using several chromatographic methods. Structural elucidation was achieved by using infrared, MS and NMR spectra. The isolation process from the species has afforded 5 known compounds;  isocalanone (1) and 1-hydroxy-7-methoxy-9H-xanthen-9-one (2), lupeol (3), friedelin (4) and diethylene glycol dibenzoate (5). The chloroform and methanol extract showed strong inhibitions against S. aureus, B. subtilis, P. aeruginosa and E. coli with the MIC and MBC values ranging from 225 and 112.5 µg/mL. Isocalanone (1) and the methanol extract of C. ferrugineum showed potent antioxidant activity with the IC50 values of 28 ± 5.23 and 35 ± 3.69 µg/mL compared to ascorbic acid, respectively. The results obtained from this study emphasized the potential of the species as antimicrobial and antioxidant agents.


Author(s):  
Jamal Kasaian ◽  
Peiman Alesheikh ◽  
Ameneh Mohammadi

Context: Essential oils are secondary metabolites with versatile organic structures that, due to their compounds, have useful medicinal properties. There are about 250 species of the genus of Scutellaria perennial flowering plants from the Lamiaceae family. Its application for the treatment of allergy, inflammatory, hyperlipidemia, arteriosclerosis, hypertension, and hepatitis has a long history. Evidence Acquisition: Various studies on the chemical compounds of the Scutellaria genus have identified several ‎compounds, especially essentials oils. The current review is based on the evidence found in Chemical Abstract, Science Direct, Scopus, PubMed, Web of Knowledge, and Google Scholar databases. Results: Many studies on the chemical components of essential oils from the Scutellaria genus have identified several compounds. We summarized the chemical compositions and biological activities of Scutellaria essential oils. Hexadecanoic acid, germacrene D, β-caryophyllene, linalool, β-farnesene, and eugenol are the main compounds in essential oils of this genus. Despite many reports about essential oils of Scutellaria species (more than 38), a large number of species have not been studied yet. Therefore, several studies should be conducted on the chemical compounds and biological activities of unstudied Scutellaria essential oils. Conclusions: This review has summarized reports on the chemistry and biological activities of Scutellaria essential oils,‎ such as antioxidant, antimicrobial, antifeedant, phytotoxic, and acaricidal toxicities, based on the recent literature.


2008 ◽  
Vol 73 (11) ◽  
pp. 1039-1049 ◽  
Author(s):  
Slavica Solujic ◽  
Slobodan Sukdolak ◽  
Nenad Vukovic ◽  
Neda Niciforovic ◽  
Snezana Stanic

In this study, the chemical components, antimicrobial and genotoxic biological activities of the acetone extract of Ambrosia artemisiifolia L. pollen were examined. Two lactones were identified: ambrosin and artesovin. The antimicrobial activity of the acetone extract of A. artemisiifolia L. pollen was examined on ten different bacterial species using the disc diffusion method and the microdilution method in Mueller-Hinton broth dilution. The minimal inhibitory concentration of the acetone extract of A. artemisiifolia pollen varied between 1.25-6.50 mg mL-1. The genotoxic effect of the acetone extract of A. artemisiifolia pollen on a eukaryotic model system Drosophila melanogaster was investigated using the SLRL test.


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