scholarly journals ALTERATION OF EXPERIMENTAL POLIOMYELITIS INFECTION IN THE SYRIAN HAMSTER WITH THE AID OF CORTISONE

1952 ◽  
Vol 95 (4) ◽  
pp. 347-362 ◽  
Author(s):  
Gregory Shwartzman ◽  
Alice Fisher
Keyword(s):  
Mortality Rate ◽  
Survival Time ◽  
Incubation Period ◽  
High Mortality ◽  
Syrian Hamster ◽  
Marked Reduction ◽  
Single Injection ◽  
Reciprocal Relationship ◽  
Fatal Disease ◽  
Enhancing Effect

Cortisone produces a significant enhancement of infection with MEF1 and Lansing strains of poliomyelitis virus in the Syrian hamster. The enhancement manifests itself in increased severity of symptoms, shortening of the incubation period, marked reduction in survival time and a high mortality rate. The effect of cortisone is protracted, the duration depending on the dose used. There is a reciprocal relationship between the dose of cortisone and the amount of virus, the larger the dose of the hormone, the smaller the amount of virus being necessary to produce the infection. An amount of virus of low infectivity causes amarked disease with a high mortality rate in hamsters receiving a single injection of 3 mg. of cortisone, while a dose as small as 2 mg. gives a highly fatal disease with a stronger concentration of the virus. There is a 2 log increase in the concentration of the virus in cortisone-treated hamsters. Hamsters from various sources seem to respond differently to the enhancing effect of cortisone, one breed showing no enhancement of the infection with the Lansing strain. Hormones other than cortisone, i.e., DCA, progesterone, diethylstilbestrol, and fast and slow acting ACTH injected repeatedly fail to modify the poliomyelitis infection in the hamster.

Business Incubation Initiatives Impact on Entrepreneurs and SMEs

2022 ◽  
Vol 12 (1) ◽  
pp. 0-0
Keyword(s):  
Mortality Rate ◽  
Incubation Period ◽  
High Mortality ◽  
Exploratory Study ◽  
Qualitative Data ◽  
Policy Implications ◽  
Business Incubation ◽  
Methodological Triangulation ◽  
The Impact

Business incubation (BI) is a strategic tool that helps a country to grow its entrepreneurial base and reduce the high mortality rate of SMEs. Kingdom of Eswatini adopted the business incubation initiatives to promote entrepreneurship and SME development. To date, no data exist on the impact made by business incubation initiatives. Adopting methodological triangulation of both quantitative and qualitative data collected through questionnaires and interviews where the participants consisted of SME owners, BI managers, and BI trainers, this exploratory study aims to investigate business incubation initiatives' impact on entrepreneurs and SMEs. Findings reflect that BIs measure their impact by seeing an increase in revenue, increase in the number of people employed, and SME survival post the incubation period. Though SMEs agreed that the BI effects positively, the study also revealed that some SMEs remained in the incubation for more than 10 years. Policy implications emerging are the need to introduce graduation policy and proper determination of requirements for incubation.

scholarly journals Congenital nephrotic syndrome: preemptive bilateral nephrectomy and dialysis before renal transplantation.

1992 ◽  
Vol 3 (2) ◽  
pp. 260-263
Author(s):  
M S Kim ◽  
W Primack ◽  
W E Harmon
Keyword(s):  
Nephrotic Syndrome ◽  
Renal Transplantation ◽  
Mortality Rate ◽  
High Mortality ◽  
Congenital Nephrotic Syndrome ◽  
First Year ◽  
Bilateral Nephrectomy ◽  
Related Complication ◽  
Fatal Disease ◽  
First Year Of Life

Congenital nephrotic syndrome (CNS) is a rare and uniformly fatal disease if it is not treated. Although renal transplantation has been a successful treatment, there remains a high mortality rate during the first year of life before transplantation. From 1979 to 1987, four patients with CNS, all of whom died before they could undergo renal transplantation were treated. On the basis of this clinical experience, early elective bilateral nephrectomy and dialysis for infants with CNS were initiated to improve overall outcome. From 1987 to 1989, this protocol has been used on four consecutive patients with CNS. In these patients, bilateral nephrectomy was performed only after patients suffered a serious CNS-related complication that occurred between 4 and 6 months of age. Despite nephrectomy and the need for chronic dialysis, all patients grew at normal or accelerated rates. By 16 months of age, all patients underwent successful renal transplantation.

Emamectin benzoate is a safe and effective anthelmintic against coelomic nematode Philometra rubra in striped bass Morone saxatilis

2020 ◽  
Vol 142 ◽  
pp. 47-53
Author(s):  
K Béland ◽  
G Séguin ◽  
S Lair
Keyword(s):  
Mortality Rate ◽  
Striped Bass ◽  
High Mortality ◽  
Morone Saxatilis ◽  
Treatment Results ◽  
Emamectin Benzoate ◽  
Once Daily ◽  
Fish Hatchery ◽  
Parasitic Burden

An unusually high mortality rate due to verminous (Philometra rubra) coelomitis was documented in wild-hatched striped bass Morone saxatilis raised in a fish hatchery as part of a stock restoration program. To decrease the parasitic burden and therefore potentially minimize mortality, the effectiveness of 2 different anthelmintics was evaluated. Two trials were conducted on wild-collected fingerlings naturally infected by P. rubra. In 2006, 144 yearling fish were randomly assigned to 4 experimental groups: (1) levamisole (Levasol®) at 2 mg l-1 via immersion for 8 h once weekly for 3 wk; (2) levamisole at a dose of 2.5 mg kg-1 biomass via feed once daily for 7 d; (3) emamectin benzoate (Slice®) at a dose of 0.05 mg kg-1 biomass via feed once daily for 7 d; and (4) control. Emamectin successfully eliminated live nematodes in 84.9% of the fish, whereas the administration of levamisole, either via immersion or feed, was not successful in significantly reducing the number of live P. rubra. In 2007, the administration of the same dosage of emamectin to approximately 1000 naturally infected yearling striped bass was associated with a 100% mortality rate of P. rubra in the 30 fish randomly examined 5 wk after the beginning of the treatment. Results of these trials indicate that, at the dosage used, the administration of emamectin at the end of the summer is safe for striped bass yearlings and considerably reduces the prevalence and intensity of the infection by this parasite.

Inovasi Teknologi Pembuatan Pakan Udang dengan Penambahan Tepung Kopasanda (Chromolaena odorata L.) di Desa Tamangapa Kecamatan Ma’rang Kab. Pangkep

2019 ◽  
Vol 3 (2) ◽  
pp. 140
Author(s):  
Harlina Harlina ◽  
Hadijah Hadijah ◽  
Kamaruddin Kamaruddin ◽  
Ernaningsih Ernaningsih
Keyword(s):  
Mortality Rate ◽  
Community Service ◽  
High Mortality ◽  
Raw Materials ◽  
Development Program ◽  
Chromolaena Odorata ◽  
Farmed Fish ◽  
Counseling Training ◽  
Shrimp Feed ◽  
Simple Technology

Tamangapa village, Ma’rang district is part of the community development program conducted by Universitas Muslim Indonesia in Pangkajene Kepulauan regency. The local shrimp farmers of Tamangapa village have been facing major issue due to expensive artificial feed and high mortality rate. In order to solve the needs of feed and high mortality rate for farmed fish or shrimp, the source of the natural ingredients using kopasanda leaves Chromolaena odorata L is required. The use of a natural ingredient is also used to prevent the vibriosis using simple technology such as the utilization of local raw materials which is affordable and locally available. The present community service aimed to provide the proper knowledge and skills to members of the fish/shrimp farmer’s group through counseling, training and mentoring. This community service program encouraged the local farmers to be able to utilize the local raw materials as a source of shrimp feed, use the feed pellet machine, and packaging leading to independent feed production. The participatory training method, lectures, forum group discussions, and practices of making shrimp feed and packaging were applied. The Implementation of the Community Partnership Program of Shrimp and Fish Cultivation Groups is independently able to produce organic fish or shrimp feed for farmer’s group leading to higher productivity of aquaculture.

Candida albicans endocarditis involving a normal native aortic valve in an immunocompetent patient

2020 ◽  
Vol 13 (11) ◽  
pp. e236902
Author(s):  
Taha Sheikh ◽  
Jeremy C Tomcho ◽  
Mohammed T Awad ◽  
Syeda Ramsha Zaidi
Keyword(s):  
Candida Albicans ◽  
Mortality Rate ◽  
Aortic Valve ◽  
High Mortality ◽  
Treatment Options ◽  
Immunocompetent Patient ◽  
Fungal Endocarditis ◽  
Appropriate Treatment ◽  
Mechanical Valves ◽  
Serious Infection

Fungal endocarditis, specifically from Candida species, is a rare but serious infection with a high mortality rate. Most cases occur in bioprosthetic or mechanical valves and are uncommon in native, structurally normal valves. When Candida endocarditis is detected and appropriate treatment is initiated earlier, there is an improvement in mortality. While the recommendation is usually to treat with a combination of surgery and antifungal medications, patient comorbidities may limit treatment options.

scholarly journals Bowel necrosis in patient with severe case of COVID-19: a case report

BMC Surgery ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Daniel Ardian Soeselo ◽  
Wirawan Hambali ◽  
Sandy Theresia
Keyword(s):  
Case Report ◽  
Mortality Rate ◽  
Critically Ill ◽  
High Mortality ◽  
Severe Case ◽  
Bowel Necrosis ◽  
Case Presentation ◽  
Gastrointestinal Manifestations ◽  
Emergent Laparotomy

Abstract Background In patients who are critically ill with COVID-19, multiple extrapulmonary manifestations of the disease have been observed, including gastrointestinal manifestations. Case presentation We present a case of a 65 year old man with severe COVID-19 pneumonia that developed hypercoagulation and peritonitis. Emergent laparotomy was performed and we found bowel necrosis in two sites. Conclusions Although rare, the presentation of COVID-19 with bowel necrosis requires emergency treatments, and it has high mortality rate.

SARS-CoV-2 and Tissue Damage: Current Insights and Biomaterial-based Therapeutic Strategies

2021 ◽  
Author(s):  
Himadri Roy ◽  
Rupali Singh ◽  
Deepa Ghosh
Keyword(s):  
Mortality Rate ◽  
High Mortality ◽  
Tissue Damage ◽  
Therapeutic Strategies ◽  
The World ◽  
Rapid Transmission

The effect of SARS-CoV-2 infection on humanity has gained worldwide attention and importance due to its rapid transmission, lack of treatment and high mortality rate. While scientists across the world...

Modern imagine methods in diagnostics of acute pancreatitis in clinical practice

2020 ◽  
pp. 14-25
Author(s):  
G. R. Ahunova ◽  
R. R. Ahunova
Keyword(s):  
Acute Pancreatitis ◽  
Clinical Practice ◽  
Mortality Rate ◽  
High Mortality ◽  
Surgical Pathology ◽  
Diagnostic Radiology ◽  
Common Disease ◽  
Review Of The Literature ◽  
Abdominal Organs ◽  
Comprehensive Examination

Acute pancreatitis is one of the most frequent and formidable diseases, and rates as one of the most common disease in the structure of acute surgical pathology of the abdominal organs. In the last decade, there has been an increase in the proportion of necrotic forms of the disease with damage to various departments of the retroperitoneal space and a stably high mortality rate. The diagnostics problem of acute pancreatitis is still relevant due to difficulties that persist despite the possibility of a comprehensive examination of patients upon admission to the hospital and during treatment. This article presents a review of the literature, reflecting the state of the problem and aspects of diagnostic radiology of acute pancreatitis.

Spectrum of liver diseases occurring solely in pregnancies carrying male fetuses: A case series

2021 ◽  
Vol 1 (2) ◽  
Author(s):  
Eva koulaymi ◽  
◽  
Mayssaloun khairallah ◽  
Zeinab Haroun ◽  
Jihad Al Hassan ◽  
...  
Keyword(s):  
Liver Disease ◽  
Mortality Rate ◽  
High Mortality ◽  
Liver Diseases ◽  
Case Series ◽  
Specific Effect ◽  
Related Liver Disease ◽  
Insight Into

Liver disease affects nearly 3% of pregnancies. It is a challenging topic for obstetricians as it can be fatal for both, the mother and the fetus. They carry a high mortality rate reaching 25%. Sex-specific effect on the expression of pregnancy-related liver diseases is largely unknown. We present several cases of familial pregnancy-related liver diseases that were expressed solely when the mothers had male fetuses, ending with deleterious outcomes. Liver disease was not expressed when they had female fetuses. These cases provide a novel insight into the diversity of pregnancy-related liver disease complications expression among sex.

Sign in / Sign up

Export Citation Format

Share Document