Paradigm Function Morphology: Assumptions and Innovations

2020 ◽  
Author(s):  
Gregory Stump
Keyword(s):  
Inflectional Morphology ◽  
Formal Representation ◽  
The Core ◽  
Recent Innovation ◽  
Morphological Theory ◽  
Per Se ◽  
Fundamental Insight ◽  
Definition Of

Paradigm Function Morphology (PFM) is an evolving approach to modeling morphological systems in a precise and enlightening way. The fundamental insight of PFM is that words have both content and form and that in the context of an appropriately organized lexicon, a language’s morphology deduces a complex word’s form from its content. PFM is therefore a realizational theory: a language’s grammar and lexicon are assumed to provide a precise characterization of a word’s content, from which the language’s morphology then projects the corresponding form. Morphemes per se have no role in this theory; by contrast, paradigms have the essential role of defining the content that is realized by a language’s morphology. At the core of PFM is the notion of a paradigm function, a formal representation of the relation between a word’s content and its form; the definition of a language’s paradigm function is therefore the definition of its inflectional morphology. Recent elaborations of this idea assume a distinction between content paradigms and form paradigms, which makes it possible to account for a fact that is otherwise irreconcilable with current morphological theory—the fact that the set of morphosyntactic properties that determines a word’s syntax and semantics often differs from the set of properties (some of them morphomic) that determines a word’s inflectional form. Another recent innovation is the assumption that affixes and rules of morphology may be complex in the sense that they may be factored into smaller affixes and rules; the evidence favoring this assumption is manifold.

Introduction: Psychiatric Research and Extraordinary Science

2017 ◽  
Keyword(s):  
Scientific Research ◽  
Psychiatric Research ◽  
Research Practice ◽  
Research Domain Criteria ◽  
Current Crisis ◽  
The Core ◽  
Research Programs ◽  
Research Domain

This chapter introduces the core thematic ideas of the present volume: that psychiatric research is in crisis, that it has entered a period of extraordinary science, and that a fully adequate response to the crisis should be responsive to the perspectives and interests of persons. We identify various sources of the crisis, drawing special attention to controversies concerning the role of the DSM in psychiatric research. And, we identify different strategies of response to the current crisis, including approaches that emphasize the importance of personal perspectives and the needs of the clinic and those that emphasize the important role of various scientific research programs. Further, we survey various developments (e.g., debates over fundamentals and a role for philosophical analysis, probing of the problems of the DSM framework, relaxation of standard forms of research practice, the introduction of the Research Domain Criteria initiative and other novel research programs) that are jointly suggestive of Thomas Kuhn’s characterization of periods of crisis that can arise in scientific research and of the “extraordinary science” that ensues. We suggest that this Kuhnian framework is useful for understanding the state of psychiatric research and it provides a framework for thinking about responses to the current crisis. We conclude with brief overviews of the contributions to the volume, each of which provides such a response.

scholarly journals Experimental intravascular hemolysis induces hemodynamic and pathological pulmonary hypertension: association with accelerated purine metabolism

2018 ◽  
Vol 8 (3) ◽  
pp. 204589401879155 ◽  
Author(s):  
Victor P. Bilan ◽  
Frank Schneider ◽  
Enrico M. Novelli ◽  
Eric E. Kelley ◽  
Sruti Shiva ◽  
...  
Keyword(s):  
Pulmonary Hypertension ◽  
Rat Model ◽  
Vascular Remodeling ◽  
Purine Nucleoside Phosphorylase ◽  
Autologous Blood ◽  
Systolic Pressure ◽  
Per Se ◽  
Parenchymal Injury

Pulmonary hypertension (PH) is emerging as a serious complication associated with hemolytic disorders, and plexiform lesions (PXL) have been reported in patients with sickle cell disease (SCD). We hypothesized that repetitive hemolysis per se induces PH and angioproliferative vasculopathy and evaluated a new mechanism for hemolysis-associated PH (HA-PH) that involves the release of adenosine deaminase (ADA) and purine nucleoside phosphorylase (PNP) from erythrocytes. In healthy rats, repetitive administration of hemolyzed autologous blood (HAB) for 10 days produced reversible pulmonary parenchymal injury and vascular remodeling and PH. Moreover, the combination of a single dose of Sugen-5416 (SU, 200 mg/kg) and 10-day HAB treatment resulted in severe and progressive obliterative PH and formation of PXL (Day 26, right ventricular peak systolic pressure (mmHg): 26.1 ± 1.1, 41.5 ± 0.5 and 85.1 ± 5.9 in untreated, HAB treated and SU+HAB treated rats, respectively). In rats, repetitive administration of HAB increased plasma ADA activity and reduced urinary adenosine levels. Similarly, SCD patients had higher plasma ADA and PNP activity and accelerated adenosine, inosine, and guanosine metabolism than healthy controls. Our study provides evidence that hemolysis per se leads to the development of angioproliferative PH. We also report the development of a rat model of HA-PH that closely mimics pulmonary vasculopathy seen in patients with HA-PH. Finally, this study suggests that in hemolytic diseases released ADA and PNP may increase the risk of PH, likely by abolishing the vasoprotective effects of adenosine, inosine and guanosine. Further characterization of this new rat model of hemolysis-induced angioproliferative PH and additional studies of the role of purines metabolism in HA-PH are warranted.

Morphological Change

2017 ◽  
Author(s):  
Carola Trips
Keyword(s):  
Morphological Change ◽  
Point Of View ◽  
General View ◽  
Inflectional Morphology ◽  
Linguistic Change ◽  
Morphological Theory ◽  
History Of ◽  
Abstract Level ◽  
Types Of Change

Morphological change refers to change(s) in the structure of words. Since morphology is interrelated with phonology, syntax, and semantics, changes affecting the structure and properties of words should be seen as changes at the respective interfaces of grammar. On a more abstract level, this point relates to linguistic theory. Looking at the history of morphological theory, mainly from a generative perspective, it becomes evident that despite a number of papers that have contributed to a better understanding of the role of morphology in grammar, both from a synchronic and diachronic point of view, it is still seen as a “Cinderella subject” today. So there is still a need for further research in this area. Generally, the field of diachronic morphology has been dealing with the identification of the main types of change, their mechanisms as well as the causes of morphological change, the latter of which are traditionally categorized as internal and external change. Some authors take a more general view and state the locus of change can be seen in the transmission of grammar from one generation to the next (abductive change). Concerning the main types of change, we can say that many of them occur at the interfaces with morphology: changes on the phonology–morphology interface like i-mutation, changes on the syntax–morphology interface like the rise of inflectional morphology, and changes on the semantics–morphology like the rise of derivational suffixes. Examples from the history of English (which in this article are sometimes complemented with examples from German and the Romance languages) illustrate that sometimes changes indeed cross component boundaries, at least once (the history of the linking-s in German has even become a prosodic phenomenon). Apart from these interface phenomena, it is common lore to assume morphology-internal changes, analogy being the most prominent example. A phenomenon regularly discussed in the context of morphological change is grammaticalization. Some authors have posed the question of whether such special types of change really exist or whether they are, after all, general processes of change that should be modeled in a general theory of linguistic change. Apart from this pressing question, further aspects that need to be addressed in the future are the modularity of grammar and the place of morphology.

scholarly journals The role of deliberate practice in expert performance: revisiting Ericsson, Krampe & Tesch-Römer (1993)

2019 ◽  
Vol 6 (8) ◽  
pp. 190327 ◽  
Author(s):  
Brooke N. Macnamara ◽  
Megha Maitra
Keyword(s):  
Individual Differences ◽  
Effect Size ◽  
Deliberate Practice ◽  
Skill Level ◽  
Expert Performance ◽  
Double Blind ◽  
The Core ◽  
Definition Of ◽  
Practice Teacher

We sought to replicate Ericsson, Krampe & Tesch-Römer's (Ericsson, Krampe & Tesch-Römer 1993 Psychol. Rev. 100 , 363–406) seminal study on deliberate practice. Ericsson et al . found that differences in retrospective estimates of accumulated amounts of deliberate practice corresponded to each skill level of student violinists. They concluded, ‘individual differences in ultimate performance can largely be accounted for by differential amounts of past and current levels of practice’ (p. 392). We reproduced the methodology with notable exceptions, namely (i) employing a double-blind procedure, (ii) conducting analyses better suited to the study design, and (iii) testing previously unanswered questions about teacher-designed practice—that is, we examined the way Ericsson et al . operationalized deliberate practice (practice alone), and their theoretical but previously unmeasured definition of deliberate practice (teacher-designed practice), and compared them. We did not replicate the core finding that accumulated amounts of deliberate practice corresponded to each skill level. Overall, the size of the effect was substantial, but considerably smaller than the original study's effect size. Teacher-designed practice was perceived as less relevant to improving performance on the violin than practice alone. Further, amount of teacher-designed practice did not account for more variance in performance than amount of practice alone. Implications for the deliberate practice theory are discussed.

The Technocene or Technology as (Neo)Environment

2017 ◽  
Vol 21 (2) ◽  
pp. 243-281 ◽  
Author(s):  
Agostino Cera ◽  
Keyword(s):  
Philosophy Of Technology ◽  
The Other ◽  
Current Form ◽  
Nominative Case ◽  
The Core ◽  
The World ◽  
Conditio Humana ◽  
The One ◽  
Definition Of

Abstract: While putting forward the proposal of a “philosophy of technology in the nominative case,” grounded on the concept of Neoenvironmentality, this paper intends to argue that the best definition of our current age is not “Anthropocene.” Rather, it is “Technocene,” since technology represents here and now the real “subject of history” and of (a de-natured) nature, i.e. the (neo)environment where man has to live.This proposal culminates in a new definition of man’s humanity and of technology. Switching from natura hominis to conditio humana, the peculiarity of man can be defined on the basis of an anthropic perimeter, the core of which consists of man’s worldhood: man is that being that has a world (Welt), while animal has a mere environment (Umwelt). Both man’s worldhood and animal’s environmentality are derived from a pathic premise, namely the fundamental moods (Grundstimmungen) that refer them to their respective findingness (Befindlichkeit).From this anthropological premise, technology emerges as the oikos of contemporary humanity. Technology becomes the current form of the world – and so gives birth to a Technocene – insofar as it introduces in any human context its ratio operandi and so assimilates man to an animal condition, i.e. an environmental one. Technocene corresponds on the one side to the emergence of technology as (Neo)environment and on the other to the feralization of man. The spirit of Technocene turns out to be the complete redefinition of the anthropic perimeter.While providing a non-ideological characterization of the current age, this paper proposes the strategy of an ‘anthropological conservatism,’ that is to say a pathic desertion understood as a possible (pre)condition for the beginning of an authentic Anthropocene, i.e. the age of an-at-last-entirely-human-man.

scholarly journals Beyond the Binary: Rethinking Gender Neutrality in Indian Rape Law

2016 ◽  
Vol 11 (2) ◽  
pp. 367-397
Author(s):  
Harshad PATHAK
Keyword(s):  
Human Rights ◽  
Rape Law ◽  
The Common ◽  
Definition Of ◽  
Human Rights Based Approach ◽  
Gender Neutrality ◽  
Gender Specific ◽  
Indian Penal Code

AbstractDespite expanding the definition of rape under the Indian Penal Code to include non-penile-vaginal acts of penetration, the said definition continues to conform to a gender-specific notion of rape, based on a predetermined characterization of the victim-perpetrator framework on the basis of their genders. Herein, I will critique this idea of gender specificity in Indian rape law on the grounds that it reinforces a binary notion of gender, and results in gross underinclusion. Instead, it is more appropriate to adopt a human-rights-based approach in defining the offence of rape, and negate the role of gender in identifying the victims and perpetrators of an act of rape. The argument is pillared on a state’s obligation to not discriminate on the basis of sex, the recognition of transgender rights, and an assessment of the common grounds for opposing gender neutrality in Indian rape law.

scholarly journals The Cheshire explainer. Musings about the training of explainers

2016 ◽  
Vol 15 (04) ◽  
pp. C06
Author(s):  
Antonio Gomes da Costa
Keyword(s):  
Science Communication ◽  
Clear Definition ◽  
Top Down ◽  
Scientific Training ◽  
The Public ◽  
The Core ◽  
Main Factors ◽  
State Of Affairs ◽  
Definition Of

The profession of explainer is still pretty much undefined and underrated and the training of explainers is many times deemed to be a luxury. In the following pages we make the argument that three main factors contribute to this state of affairs and, at the same time, we try to show why the training of explainers should really be at the core of any science communication institution. These factors are: an erroneous perception of what a proper scientific training means for explainers; a lack of clear definition of the aptitudes and role of explainers required by institutions that are evolving and diversifying their missions; and an organizational model based on top-down practices of management and activity development which underappreciates the potential of the personnel working directly with the public.

Part II Ambit of Protection, 6 Investment

2017 ◽  
Author(s):  
McLachlan Campbell ◽  
Shore Laurence ◽  
Weiniger Matthew
Keyword(s):  
Minority Shareholders ◽  
Central Concept ◽  
Holding Companies ◽  
Host State ◽  
The Core ◽  
Investment Treaties ◽  
Definition Of ◽  
Portfolio Investments ◽  
Made In

Chapter 6 explores the central concept of ‘investment’. It first considers the core question of the definition of ‘investment’ under the ICSID Convention and under investment treaties. It then takes up four important issues: (1) the time when an investment is made in relation to the temporal scope of the treaty protections; (2) the extent to which pre-contract investment may obtain treaty protection; (3) the place of an investment; and (4) the role of host State law in defining ‘investment’. It then analyses a set of problems that arise out of indirect investments: the relation between the losses suffered by a subsidiary in the host State and the investor’s investment; the rights of minority shareholders; claims brought by holding companies; corporate restructuring as a means to gain the advantage of investment treaties; the position of ultimate beneficiaries; and the position of portfolio investments.

Discussion Forum: The Dawkins Reforms and Psychology

1995 ◽  
Vol 8 ◽  
pp. 40-43
Author(s):  
Alan Robson
Keyword(s):  
Applied Research ◽  
Free Enterprise ◽  
Free Markets ◽  
Tertiary Institutions ◽  
The Core ◽  
Lower Tier ◽  
Research And Teaching ◽  
Technical Institutes ◽  
Definition Of

Suggestions that psychology lacks academic substance are common. Recently, in an article in the Australian newspaper, Emeritus Professor John Sutcliffe described it as a “dicky-shirt” discipline -- all form and no substance (Sutcliffe, 1994). He wrapped his observation into a general attack on the Dawkins education reforms which he correctly blames for eroding the intellectual core of Australian academic life. Many academics share Sutcliffe's concerns.The Dawkins reforms are an uneasy blend of populism and commercialism aimed at achieving the Labour government's economic goal of a “clever country”. Most conspicuously, they have involved the incorporation of former technical institutes into large multi-campus universities. The result has been the physical extension of a university presence across the country into some improbable rural backwaters. Inevitably these dramatic changes in the size and spread of universities have been accompanied by a change in the definition of the role of universities. Topics of study which were once the domain of lower tier tertiary institutions now find a place in the core academic centres. The result has been a shift in the balance of academic interest from abstract to applied research and teaching.Feeding into these changes has been what Sutcliffe describes as a “money-driven” ethos. After decades of intervention to redress inequalities and irrationalities stemming from the operation of free markets, Labour governments in various parts of the West have capitulated to historical forces and pre-emptively embraced the free enterprise policies of the traditional right.

scholarly journals Role of metformin pregravid preparation patients with prediabetes impaired glucose toletance

2015 ◽  
Vol 64 (3) ◽  
pp. 18-25
Author(s):  
Evgeniy Konstantinovich Komarov ◽  
Tamara Aleksandrovna Pluzhnikova
Keyword(s):  
Low Frequency ◽  
Free Testosterone ◽  
Control Group ◽  
Perinatal Complications ◽  
Insulin Resistence ◽  
Group I ◽  
Definition Of ◽  
High Level

Tasks of investigation were concluded the characterization of insulin resistence (IR) and hormonal features in patients with prediabetes and influence of diet or metformin on the course of pregnancy and perinatal complications. There were examined 61 womans. The OGTT, definition of insulin levels in plasma and index IR were performed in all patiens. OGTT and index IR were normal in 14 womans (control group I). OGTT was normal but index IR was impared in 33 womans (group IR - II). From this group 22 womans were treated with diet (II A group) and 11 womans treated with metformin (IIB group). OGTT and index IR were abnormal in 14 womans (impared OGTT - III group), they were treated with metformin. Dose of metformin was 1500 mg/d, threatment was continueted for 3-4 manths. Conclusion: Used indexes IR basal and two hour after glucose load were significant in definition of normal and decreased insulin sensitivity (IR). Presence of IR is accompanied by high level of free testosterone in blood without impared secretion of ovarian and suprarenal androgens. There was impared sensitivity of endometrium of secretory stage. The frequency of obstetric and perinatal complications in patients receiving diet not differ from patients treated with metformin. There was only a tendercy to low frequency of threatening miscarriages befor 12 weeks of gestations in paitiens receiving metformin. Development of GDM was observed in 13,1 % of patiens only with presence of IR. The use of metformin in pregravidal stage preserved the development of macrosomia in offsprings of patients with prediabetes.

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