scholarly journals 326 Resorbable Composite Materials for Fracture Fixation

2021 ◽  
Vol 108 (Supplement_6) ◽  
Author(s):  
B Baljer ◽  
P Melo ◽  
M German ◽  
K Dalgarno

Abstract Introduction Titanium-based fracture fixation devices often necessitate removal in the maxillofacial region. Resorbable composite implants negate the need for a revision operation; however, concurrent devices either possess a prolonged degradation profile or bioactivity, resulting in undesirable bone deposition. To that end, a novel, fast-resorbing, non-bioactive composite material is proposed, which still possesses an osteoinductive potential, thereby aiding fracture healing. Method Three bioglasses were available (NCL1-3) as filler material. NCL2 was selected and different concentrations (5%; 20%) were added to reinforce medical grade poly(lactic-co- glycolide) (PLGA). The final compression moulded samples underwent material characterisation and an 8-week degradation assay. Results No significant difference was found between the cytotoxicity of the glasses and both the positive (apatite wollastonite) and negative (absence of glass) controls in relation to mesenchymal stem cells or osteoblasts. pH and weight change analyses showed an increased rate of degradation with an increase in glass concentration. Although reinforcement with NCL2 did not increase the mechanical properties of the polymer, no significant difference was present between the mechanical properties of the composites, and, as made, both 5% and 20% composites had flexural strengths of 13MPa±5, which did not decrease significantly during degradation. Conclusions NCL1-3 are non-toxic in the context of fracture healing. The PLGA/NCL2 composite is not suitable for fracture fixation as produced currently, due to increased polymer degradation and lower mechanical properties. However, 20% compositions are recommended for future research, as they would hypothetically provide a superior osteoinductive response without significantly lowering the mechanical properties of the composite.

2018 ◽  
Vol 164 (4) ◽  
pp. 277-280 ◽  
Author(s):  
Jason Guey ◽  
S Rodrigues ◽  
A Pullen ◽  
B Shaw ◽  
D C Kieser

PurposeBallistic gelatin is commonly used as a validated surrogate for soft tissue during terminal ballistic testing. However, the effect of a delay between production and testing of a gelatin mould remains unknown. The aim of this study was to determine any potential effects of ageing on ballistic gelatin.MethodsDepth of penetration (DoP) of 4.5 mm spherical fragment simulating projectiles was ascertained using mixtures of 10%, 11.25% and 20% Type A 250 Bloom ballistic gelatin. Testing was performed daily for 5 days using velocities between 75 and 210 m/s. DoP at day 5 was statistically compared with day 1, and net mass change was recorded daily.ResultsNo significant difference was found for DoP observed with time in any of the samples (P>0.05). Spearman correlation was excellent in all moulds. The moulds with known standard calibrations remained in calibration throughout the study period. Mass loss of less than 1% was noted in all samples.ConclusionMass loss was the only quantifiable measure of changes in the blocks with time, but did not correlate with any changes in DoP. This may provide reassurance when undertaking such testing that an inadvertent delay will not significantly alter the penetration properties of the mould. Future research is recommended to determine any potential effect on the mechanical properties of gelatin at higher velocity impacts and whether the calibration corresponds to an adequate simulation under such conditions.


2021 ◽  
Vol 2 (3) ◽  
pp. 501-515
Author(s):  
Rajib Kumar Biswas ◽  
Farabi Bin Ahmed ◽  
Md. Ehsanul Haque ◽  
Afra Anam Provasha ◽  
Zahid Hasan ◽  
...  

Steel fibers and their aspect ratios are important parameters that have significant influence on the mechanical properties of ultrahigh-performance fiber-reinforced concrete (UHPFRC). Steel fiber dosage also significantly contributes to the initial manufacturing cost of UHPFRC. This study presents a comprehensive literature review of the effects of steel fiber percentages and aspect ratios on the setting time, workability, and mechanical properties of UHPFRC. It was evident that (1) an increase in steel fiber dosage and aspect ratio negatively impacted workability, owing to the interlocking between fibers; (2) compressive strength was positively influenced by the steel fiber dosage and aspect ratio; and (3) a faster loading rate significantly improved the mechanical properties. There were also some shortcomings in the measurement method for setting time. Lastly, this research highlights current issues for future research. The findings of the study are useful for practicing engineers to understand the distinctive characteristics of UHPFRC.


Author(s):  
Paul Borbas ◽  
Rafael Loucas ◽  
Marios Loucas ◽  
Maximilian Vetter ◽  
Simon Hofstede ◽  
...  

Abstract Introduction Coronal plane fractures of the distal humerus are relatively rare and can be challenging to treat due to their complexity and intra-articular nature. There is no gold standard for surgical management of these complex fractures. The purpose of this study was to compare the biomechanical stability and strength of two different internal fixation techniques for complex coronal plane fractures of the capitellum with posterior comminution. Materials and methods Fourteen fresh frozen, age- and gender-matched cadaveric elbows were 3D-navigated osteotomized simulating a Dubberley type IIB fracture. Specimens were randomized into one of two treatment groups and stabilized with an anterior antiglide plate with additional anteroposterior cannulated headless compression screws (group antiGP + HCS) or a posterolateral distal humerus locking plate with lateral extension (group PLP). Cyclic testing was performed with 75 N over 2000 cycles and ultimately until construct failure. Data were analyzed for displacement, construct stiffness, and ultimate load to failure. Results There was no significant difference in displacement during 2000 cycles (p = 0.291), stiffness (310 vs. 347 N/mm; p = 0.612) or ultimate load to failure (649 ± 351 vs. 887 ± 187 N; p = 0.140) between the two groups. Conclusions Posterolateral distal humerus locking plate achieves equal biomechanical fixation strength as an anterior antiglide plate with additional anteroposterior cannulated headless compression screws for fracture fixation of complex coronal plane fractures of the capitellum. These results support the use of a posterolateral distal humerus locking plate considering the clinical advantages of less invasive surgery and extraarticular metalware. Level of evidence Biomechanical study.


Polymers ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 1745
Author(s):  
Tamaki Hada ◽  
Manabu Kanazawa ◽  
Maiko Iwaki ◽  
Awutsadaporn Katheng ◽  
Shunsuke Minakuchi

In this study, the physical properties of a custom block manufactured using a self-polymerizing resin (Custom-block), the commercially available CAD/CAM PMMA disk (PMMA-disk), and a heat-polymerizing resin (Conventional PMMA) were evaluated via three different tests. The Custom-block was polymerized by pouring the self-polymerizing resin into a special tray, and Conventional PMMA was polymerized with a heat-curing method, according to the manufacturer’s recommended procedure. The specimens of each group were subjected to three-point bending, water sorption and solubility, and staining tests. The results showed that the materials met the requirements of the ISO standards in all tests, except for the staining tests. The highest flexural strength was exhibited by the PMMA-disk, followed by the Custom-block and the Conventional PMMA, and a significant difference was observed in the flexural strengths of all the materials (p < 0.001). The Custom-block showed a significantly higher flexural modulus and water solubility. The water sorption and discoloration of the Custom-block were significantly higher than those of the PMMA-disk, but not significantly different from those of the Conventional PMMA. In conclusion, the mechanical properties of the three materials differed depending on the manufacturing method, which considerably affected their flexural strength, flexural modulus, water sorption and solubility, and discoloration.


Author(s):  
O Kocar ◽  
H Livatyalı

An aluminized 22MnB5 (Boron) steel sheet, used for structural parts in the automotive industry, was subjected to press-hardening followed by austenitizing, both in a conventional furnace and via the conductive (electric resistance) heating method, an innovative technique based on the Joule’s principle for fast heating of the sheet metal. Conductive heating presents a number of advantages over the in-furnace heating method. These include a more efficient use of energy, as well as the requirement of less time and space for heating, thus lowering costs. After press-hardening was performed using both methods, the microstructural and mechanical characterizations of both specimens were examined for optical microscopy, hardness, tensile strength, and high-speed impact tests. The results showed that the press-hardening process transformed the ferritic–pearlitic microstructure in the as-received state into martensite after die quenching and caused a substantial increase in hardness and strength at the expense of ductility and impact toughness. On the other hand, no significant difference was observed in either the microstructure or mechanical properties with respect to the heating method used. The results obtained in the present investigation concur with the findings of current literature.


Author(s):  
Zaky Machmuddah ◽  
St. Dwiarso Utomo ◽  
Entot Suhartono ◽  
Shujahat Ali ◽  
Wajahat Ali Ghulam

The coronavirus pandemic has spread all over the world, affecting both the health and economic sectors. The aim of this research was to observe stock prices of customer goods before and after the COVID-19 pandemic using event study and the comparison test. The sample included data of daily closing stock prices and volume of stock trade during the three months before (−90 days) and after (+90 days) the occurrence of the COVID-19 pandemic ongoing, totaling 2670 observation data both before and after the COVID-19 pandemic, for a total of 5340. The research findings indicate a significant difference between the daily closing stock price and volume of stock trade before and after the COVID-19 pandemic. The current research has both theoretical and practical implications: the findings strengthen the efficient market hypothesis, which states that the more complete the provided information, the more efficient the market. The practical implication is that investors should be careful when choosing to invest. Investors should choose customer goods sector companies that provide products that are much needed by customers, for example, pharmacy, food, beverages, etc. Future research is needed to investigate the long-term impact of the pandemic on the economy.


2013 ◽  
Vol 746 ◽  
pp. 394-399
Author(s):  
Niwat Anuwongnukroh ◽  
Yosdhorn Chuankrerkkul ◽  
Surachai Dechkunakorn ◽  
Pornkiat Churnjitapirom ◽  
Theeralaksna Suddhasthira

The archwire is generally used in fixed appliances for orthodontic treatment to correct dental malocclusion. However, it is interesting to know whether general purpose stainless steel wire could replace commercial orthodontic archwire in orthodontic practice for economic reasons. The purpose of this study was to determine the bending properties of general purpose stainless steel wire compared with commercial orthodontic stainless steel wires after forming as an archwire for orthodontic use. The samples used in this study were 90 general purpose and 45 commercial (Highland) round stainless steel wires in 0.016, 0.018, and 0.020 sizes (30 general purpose and 15 commercial wires for each size). All 15 general purpose stainless steel wires with different sizes were formed into orthodontic archwire with a Universal Testing Machine. All samples were tested (three-point bending test) for mechanical properties. The results showed no significant difference between general purpose and commercial orthodontic wires in size 0.016 for 0.1 mm offset bending force, 0.2% yield strength, and springback. Although many mechanical properties of general purpose wires differed from commercial wires, their values conformed to other previous studies within the range of clinical acceptance. In conclusion, orthodontic formed general purpose round stainless steel wires had statistically different (p <0.05) mechanical properties from commercial orthodontic stainless steel wires (Highland) but the mechanical properties were acceptable to use in orthodontic treatment.


2016 ◽  
Vol 11 (1) ◽  
pp. 36-45 ◽  
Author(s):  
Maya Sussman ◽  
Elizabeth Goodier ◽  
Izabella Fabri ◽  
Jessica Borrowman ◽  
Sarah Thomas ◽  
...  

Background: In-hospital pain services (IPS) are commonplace, but evidence of efficacy is inadequate, and patients’ pain management in any hospital ward remains problematic. This service evaluation aimed to measure the effect of a contemporary IPS, its appropriate use and cost-efficacy. Methods: Records of 249 adults reviewed by the IPS in an inner London Teaching Hospital over an 8-month period were analysed for demographic data, interventions, workload and change in pain intensity measured by numerical rating scale (NRS). Non-parametric tests were used to evaluate differences between initial and final NRS. Spearman’s rank correlation analysis was used to create a correlation matrix to evaluate associations between all identified independent variables with the change in NRS. All strongly correlated variables (ρ > 0.5) were subsequently included in a binary logistic regression analysis to identify predictors of pain resolution greater than 50% NRS and improvement rather than deterioration or no change in NRS. Finally, referral practice and cost of inappropriate referrals were estimated. Referrals were thought to be inappropriate when pain was not optimised by the referring team; they were identified using a set algorithm. Results: Initial median NRS and final median NRS were significantly different when a Wilcoxon signed-rank test was applied to the whole cohort; Z = –5.5 (p = 0.000). Subgroup analysis demonstrated no significant difference in the ‘mild’ pain group; z = –1.1 (p = 0.253). Regression analysis showed that for every unit increase in initial NRS, there was a 62% chance of general and a 33% chance of >50% improvement in final NRS. An estimated annual cost-saving potential of £1546 to £4558 was found in inappropriate referrals and patients experiencing no benefit from the service. Discussion: Results suggest that patients with moderate to severe pain benefit most from IPS input. Also pain management resources are often distributed inefficiently. Future research is required to develop algorithms for easy identification of potential treatment responders.


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