scholarly journals Dietary Patterns and Metabolic Syndrome Among Adults with Overweight and Obesity (FS18-03-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Claire Cheng ◽  
Sharon Thompson ◽  
Caitlyn Edwards ◽  
Naiman Khan ◽  
Hannah Holscher

Abstract Objectives Metabolic syndrome (MetS) is a cluster of risk factors that are highly correlated with obesity, cardiovascular disease, and type 2 diabetes. Studies suggest that a Western diet high in fat, red meat, and added sugar is predictive of MetS, but connections between dietary patterns high in fruits, vegetables and seafoods, such as the Mediterranean diet, with this condition remain under-investigated. We aimed to assess the relation of Western and Mediterranean diet patterns with MetS among overweight or obese adults. Methods Adults (n = 151, 25–45y) with body mass index ≥25.0 kg/m2 were included in this study. MetS was evaluated using International Diabetes Federation guidelines. Waist circumference was measured with inelastic tape. Lipid and glucose concentrations were assessed with a chemical analyzer. Blood pressure was evaluated with an automatic blood pressure monitor. Habitual diet was evaluated with the National Cancer Institute's Diet History Questionnaire II (DHQII, Past Year with Portion Size). Diet variables were selected from the Food Patterns Equivalents Database. Statistical analyses included Mann-Whitney U tests and principal component analysis (PCA). Results MetS was present among 30% of the sample. Meat (P = 0.03) and added sugar (P = 0.04) intakes were greater among those with MetS, while seafood (P = 0.03) and alcohol (P = 0.02) were lower. Four components comprising 64% of dietary pattern variation included: 1) High in starchy vegetables, meat, and cheese; 2) High in non-starchy vegetables, seafood, and alcohol; 3) High in milk and added sugar but low in vegetables; and 4) High in alcohol and sodium, but low in protein and vegetables. PCA biplot grouped by prevalence of MetS indicated that seafood and non-starchy vegetables were inversely related to MetS, whereas meat, starchy vegetables, cheese, milk, added sugar, and sodium were positively correlated with MetS. Conclusions A Western diet pattern high in meat, starchy vegetables, dairy, sodium, and added sugar was related to MetS, while a Mediterranean diet pattern characterized by seafood, non-starchy vegetables, and moderate alcohol was protective against MetS. These findings highlight the links between dietary habits and MetS among adults with overweight or obesity. Funding Sources The Hass Avocado Board and the USDA National Institute of Food and Agriculture, Hatch project 1009249.

Nutrients ◽  
2019 ◽  
Vol 11 (11) ◽  
pp. 2565 ◽  
Author(s):  
Tiffany M. Newman ◽  
Mara Z. Vitolins ◽  
Katherine L. Cook

Diet is a modifiable component of lifestyle that could influence breast cancer development. The Mediterranean dietary pattern is considered one of the healthiest of all dietary patterns. Adherence to the Mediterranean diet protects against diabetes, cardiovascular disease, and cancer. Reported consumption of a Mediterranean diet pattern was associated with lower breast cancer risk for women with all subtypes of breast cancer, and a Western diet pattern was associated with greater risk. In this review, we contrast the available epidemiological breast cancer data, comparing the impact of consuming a Mediterranean diet to the Western diet. Furthermore, we will review the preclinical data highlighting the anticancer molecular mechanism of Mediterranean diet consumption in both cancer prevention and therapeutic outcomes. Diet composition is a major constituent shaping the gut microbiome. Distinct patterns of gut microbiota composition are associated with the habitual consumption of animal fats, high-fiber diets, and vegetable-based diets. We will review the impact of Mediterranean diet on the gut microbiome and inflammation. Outside of the gut, we recently demonstrated that Mediterranean diet consumption led to distinct microbiota shifts in the mammary gland tissue, suggesting possible anticancer effects by diet on breast-specific microbiome. Taken together, these data support the anti-breast-cancer impact of Mediterranean diet consumption.


2021 ◽  
Vol 31 (Supplement_3) ◽  
Author(s):  
F Scazzina

Abstract More than five years since the global commitment to the 2030 Agenda for Sustainable Development, 690 million people lack sufficient food and economic projections suggest that the COVID-19 pandemic may add an additional 83 to 132 million people to the ranks of the undernourished. Meanwhile, 1.3 billion tons of food are wasted globally each year, utilizing 38% of total energy consumption in the global food system. Child and adult overweight and obesity are increasing in almost all countries, and on a global level the cost of a healthy diet is 60% higher than the cost of a nutrient adequate diet, and almost 5 times the cost of an energy sufficient diet. The Mediterranean Diet is one of the recognized models of healthy and sustainable diets. This model has proven to promote longevity and well-being, not only by considering specific food items and dietary patterns, but also taking into account the culture and the history of populations living in that region, as well as social aspects such as tradition and conviviality. Moreover, it is strongly tied to a gastronomic background that links health with enjoyment. This may be extremely important for the implementation of feasible programs for the prevention of chronic non communicable diseases. In fact, long lasting lifestyle changes are difficult to achieve and, although health motivations may lead to satisfactory dietary compliance in the short term, pleasure remains an important determinant of any dietary change that is intended to last. While keeping traditional dietary habits at European level, the main principles of the Mediterranean diet could be taken into account to identify key features that ensure both health benefits and sustainable impact on environment. Assessing the sustainability of these products can be an effective operational approach for preserving and promoting a Mediterranean-type dietary pattern in the European region.


2014 ◽  
Vol 39 (4) ◽  
pp. 512-512 ◽  
Author(s):  
JiaWei Wang

Previous evidence showed controversial links between added sugar intake, diet quality, and increasing prevalence of metabolic syndrome (MetS) components (abdominal adiposity, dysglycemia, elevated blood pressure, reduced high-density lipoprotein cholesterol (HDL-C), and hypertriglyceridemia) in youth, and most studied only its liquid source of sugar-sweetened beverages (SSB). To better understand the extent of the detrimental effects of added sugars from both liquid and solid sources to diets in terms of nutrient and food intake and metabolic consequences in children, 3 studies were undertaken to (i) quantify the associations of added sugar intake with overall diet quality and adiposity indicators; (ii) assess whether excess weight and glucose tolerance status modifies the associations between consumption of added sugars and MetS components; and (iii) evaluate whether consumption of added sugars predicts the development of MetS components over time. Data for these studies were obtained from the Quebec Adiposity and Lifestyle Investigation in Youth cohort. Caucasian children (8 to 10 years at baseline, N = 630) with at least 1 obese biological parent were recruited from 1040 Quebec primary schools and followed-up 2 years later (N = 564). Dietary intake, including added sugars (liquid vs. solid) and Canadian Healthy Eating Index (HEI-C) was assessed in three 24-h recalls at baseline. Adiposity indicators included measured height and weight for body mass index (BMI), BMI z score, waist circumference (WC), and fat mass (by dual-energy X-ray absorptiometry). Plasma glucose and insulin were measured at fasting and by oral glucose tolerance tests to calculate the homeostasis model assessment of insulin resistance (HOMA-IR) and the Matsuda IS index (Matsuda-ISI). Systolic blood pressure (SBP), concentration of triglycerides and HDL-C were measured by standard instruments. Multivariate linear regression models were used, adjusting for age, sex, pubertal status (by Tanner stage), energy intake, fat mass, and physical activity (by 7-day accelerometer). The main findings include the following: (i) Higher consumption of added sugars from SSB or solid sources was associated with lower nutrient density and lower HEI-C. Positive associations with adiposity indicators were observed with consumption of added sugars from liquid sources only. (ii) Higher SSB consumption was associated with higher HOMA-IR and higher SBP among overweight children (≥85th BMI percentile), as well as higher SBP and higher WC among children with impaired glucose tolerance. These associations with metabolic indicators were not observed among children whose BMI was below 85th percentile. (iii) No association with added sugar intake was observed for 2-year changes in adiposity, but higher consumption of added sugars from liquid sources was associated with higher fasting glucose, higher fasting insulin, higher HOMA-IR, and lower Matsuda-ISI. In conclusion, this thesis suggested that consumption of added sugars from both solid and liquid sources was associated with a lower overall diet quality, but only added sugars from liquid sources was associated with adiposity indicators. Cross-sectional links with higher levels of SSB intake and MetS components were more evident among overweight/obese and glucose-intolerant children. Consumption of added sugars from liquid sources was not associated with changes in adiposity over 2 years, but was clearly associated with development of impaired glucose homeostasis and insulin resistance. This thesis presents further evidence on the nutritional and metabolic consequences of consuming added sugar from liquid and solid sources.


Nutrients ◽  
2020 ◽  
Vol 12 (10) ◽  
pp. 3092
Author(s):  
Jui Yee Eng ◽  
Foong Ming Moy ◽  
Awang Bulgiba ◽  
Sanjay Rampal

The rising prevalence of overweight and obesity is partly due to nutrition transition. The reported association between dietary patterns and overweight/obesity has been controversial because of inconsistent results and weak observed associations. Although it has been hypothesized that an unhealthy diet can increase obesity risk, none of the previous studies have examined the dose–response association using nonlinear dose–response analyses. This study aimed to examine the dose–response association between major dietary patterns and overweight/obesity. This was a cross-sectional study involving teachers selected through stratified multistage sampling from public schools in three Malaysian states. Dietary intake was assessed using a food frequency questionnaire, and two major dietary patterns (Western and Prudent diet) were extracted using factor analysis. Logistic regression followed by trend analysis was used to test the difference in odds of overweight and obesity in each quintile of diet score. A further analysis using restricted cubic spline models was performed to examine the dose–response associations of dietary patterns with odds of overweight/obesity. The logistic regression analysis showed that participants with the highest quintile of Western diet score were 1.4 times more likely to be overweight/obese compared to those in the lowest quintile (95% CI: 1.11, 1.83, p-trend < 0.001). The odds of overweight/obesity showed a significant increasing trend across quintiles of Western diet among both men and women (p-trend < 0.001). In the dose–response analysis, a positive linear association (Pnonlinearity = 0.6139) was observed where overweight/obesity was more likely to occur among participants with a Western diet score greater than a mean score of zero. There was an inverse trend of odds of overweight/obesity across quintiles of Prudent diet score, significant only for men (p for trend < 0.001). Linear association was found between Prudent diet score and odds of overweight/obesity among both men (Pnonlinearity = 0.6685) and women (Pnonlinearity = 0.3684) in the dose–response analysis. No threshold at the level of adherence to Prudent diet was linked to odds of overweight/obesity. Dose–response analysis indicated that women with a Western diet score greater than zero were more likely to be overweight or obese among women. In men, higher adherence to Western diet was associated with increased odds of overweight/obesity, while greater adherence to Prudent diet decreased the odds of overweight/obesity. Promoting and enhancing the consumption of Prudent diet and limit in Western diet may be used to guide the development of evidence-based diet interventions to curb overweight and obesity.


2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 1464-1464
Author(s):  
Hung Nguyen Ngoc ◽  
Wantanee Kriengsinyos ◽  
Nipa Rojroongwasinkul ◽  
Wichai Aekplakorn

Abstract Objectives Metabolically obese normal weight (MONW) individuals are subjects who have a normal body mass index (BMI), but manifest obesity-related metabolic syndrome (MetS). Nevertheless, the prevalence and correlation between MONW and dietary patterns have not been fully explored in Thais. This study aimed to investigate the national prevalence of MONW, determine which dietary patterns are consumed in Thai normal-weight adults and to identify whether those patterns were associated with the risk of MetS and its features. Methods Total 6899 Thais ≥18 years with normal BMI (18.5–22.9 kg/m2) were obtained from the Thai National Health Examination Survey IV. Sociodemographic, eating-habits, anthropometric, blood pressure and biochemical parameters were measured. MONW was diagnosed by the National Cholesterol Education Program/Adult Treatment Panel III within normal BMI. Dietary patterns were determined by means of factor analysis, and were evaluated by multiple logistic regressions for its association with MONW. Results Overall, the weighted prevalence of MONW was 9.9% (95% CI: 9.1–10.6%), particularly, the MONW prevalence was 7.2% (95% CI: 6.5–8.0%) and 13.1% (95% CI: 11.6–14.7%) in male and female respectively. Three major dietary patterns were distinguished: “westernized”, “healthy” and “carbohydrate” patterns. After controlling for potential confounders, compared with the lowest quartile, individuals in the highest quartile of the westernized and carbohydrate pattern were connected with the greater risk of MONW (adjusted odds ratio [OR]: 1.64, 95% CI: 1.25–2.17, P &lt; 0.001) and (OR: 1.57, 95% CI: 1.19–2.08, P &lt; 0.05) respectively, whereas subjects in the fourth quartile of healthy pattern reduce the risk of MONW and its components, except for elevated blood pressure and hyperglycemia (OR: 0.68, 95% CI: 0.50–0.92 for MONW, P &lt; 0.05; OR: 0.43, 95% CI: 0.28–0.68 for abdominal obesity, P &lt; 0.001; OR: 0.63, 95% CI: 0.49–0.81 for hypertriglyceridemia, P &lt; 0.001; OR: 0.67, 95% CI: 0.54–0.82 for low high-density lipoprotein cholesterol [HDL-C], P &lt; 0.01). Conclusions In Thai normal-weight adults, high consumption of whole grains, fruits, beans, juices, and dairy products is connected with a lower risk of metabolic syndrome and its features, i.e., lower risk of abdominal obesity, hypertriglyceridemia, and low HDL-C. Funding Sources This research received no funding.


2019 ◽  
Vol 149 (9) ◽  
pp. 1493-1502 ◽  
Author(s):  
Jenny L Gonzalez-Armenta ◽  
Zhengrong Gao ◽  
Susan E Appt ◽  
Mara Z Vitolins ◽  
Kristofer T Michalson ◽  
...  

ABSTRACT Background Western diets are associated with increased incidences of obesity, hypertension, diabetes, and hypercholesterolemia, whereas Mediterranean diets, richer in polyphenols, monounsaturated fats, fruits, vegetables, poultry, and fish, appear to have cardiometabolic health benefits. Previous work has included population-based studies with limited evidence for causation or animal studies focused on single macro- or micronutrients; therefore, primate animal models provide an opportunity to determine potential mechanisms underlying the effects of dietary patterns on health and disease. Objective The aim of this study was to determine the effects of whole dietary patterns, either a Western or Mediterranean diet, on skeletal muscle mitochondrial bioenergetics in cynomolgus macaques. Methods In this study, 22 adult female cynomolgus macaques (∼11–14 y by dentition) were fed either a Western or Mediterranean diet for 30 mo. The Western diet was designed to mimic the diet of a middle-aged American woman and the Mediterranean diet included key aspects of Mediterranean diets studied in humans, such as plant-based proteins and fat, complex carbohydrates, and fiber. Diets were matched on macronutrient composition (16% protein, 54% carbohydrate, and 31% fat) and cholesterol content. Skeletal muscle was collected for high-resolution respirometry, citrate synthase activity, and western blot measurements. Pearson correlation analysis between respirometry measures and measures of carbohydrate metabolism was also performed. Results We found that consumption of a Western diet resulted in significantly higher mitochondrial respiration with fatty acid oxidation (FAO) (53%), FAO + complex I (52%), complex I + II (31%), max electron transport system (ETS) (31%), and ETS rotenone sensitive (31%) than did consumption of a Mediterranean diet. In addition, measures of respiration in response to fatty acids were significantly and positively correlated with both insulin resistance and plasma insulin concentrations. Conclusions This study highlights the importance of dietary composition in mitochondrial bioenergetics and that diet can influence skeletal muscle mitochondrial respiration independently of other factors such as macronutrient composition.


2019 ◽  
Vol 22 (8) ◽  
pp. 1433-1443 ◽  
Author(s):  
Raquel Arroyo-Olivares ◽  
Rodrigo Alonso ◽  
Gracia Quintana-Navarro ◽  
Francisco Fuentes-Jiménez ◽  
Nelva Mata ◽  
...  

AbstractObjectiveHealthy lifestyle habits are the cornerstone in the management of familial hypercholesterolaemia (FH). Nevertheless, dietary studies on FH-affected populations are scarce. The present study analyses dietary habits, adherence to a Mediterranean diet pattern and physical activity in an adult population with FH and compares them with their non-affected relatives.DesignCross-sectional study.SettingData came from SAFEHEART, a nationwide study in Spain.ParticipantsIndividuals (n 3714) aged ≥18 years with a genetic diagnosis of FH (n2736) and their non-affected relatives (n 978). Food consumption was evaluated using a validated FFQ.ResultsTotal energy intake was lower in FH patients v. non-affected relatives (P<0·005). Percentage of energy from fats was also lower in the FH population (35 % in men, 36 % in women) v. those non-affected (38 % in both sexes, P<0·005), due to the lower consumption of saturated fats (12·1 % in FH patients, 13·2 % in non-affected, P<0·005). Consumption of sugars was lower in FH patients v. non-affected relatives (P<0·05). Consumption of vegetables, fish and skimmed milk was higher in the FH population (P<0·005). Patients with FH showed greater adherence to a Mediterranean diet pattern v. non-affected relatives (P<0·005). Active smoking was lower and moderate physical activity was higher in people with FH, especially women (P<0·005).ConclusionsAdult patients with FH report healthier lifestyles than their non-affected family members. They eat a healthier diet, perform more physical activity and smoke less. However, this patient group’s consumption of saturated fats and sugars still exceeds guidelines.


Author(s):  
Shahnaz Taghizadeh ◽  
Mahdieh Abbasalizad Farhangi ◽  
Fathollah Poorali

Introduction: The prevalence of childhood high blood pressure is rising fast. The possibility of high blood pressure augments with increasing body mass index (BMI), inappropriate dietary intake and lifestyle problems. The aim of this study was to investigate the correlation between blood pressure, body mass index, life style and dietary habits in children and adolescents aged 6 - 18 years in Tabriz, Iran. Methods: The present study was a cross-sectional study. Using data of the Sib software (the software used in the health transformation system) were collected. This data includes anthropometric information, some demographic factors, dietary intake and lifestyle of 425 children and adolescents with overweight and obesity. The data were analyzed by STATA software (MP 4.2 potable 2017). Results: The association between systolic blood pressure and dairy products (P = 0.02), watching TV / PC (P = 0.041), BMI quarter (P <0.001), BMI (P <0.001), and age (P <0.001) as well as the association between diastolic blood pressure with BMI quarter (P <0.001), BMI (P <0.001) and age (P <0.001) was statistically significant and the other variables did not show a meaningful statistical relationship. Conclusion: Age, BMI, less dairy consumption, and watching TV/PC has a relationship with high blood pressure. Therefore, nutritionists and health workers should consider the above considerations when making recommendations in children and adolescents with overweight and obesity.


Author(s):  
В. Б Фурдела

КЛІНІЧНІ ТА ФЕНОТИПІЧНІ ПАТЕРНИ У ШКОЛЯРІВ ІЗ НАДЛИШКОВОЮ МАСОЮ ТІЛА ТА ОЖИРІННЯМ - У статті наведено результати епідеміологічного дослідження 540 школярів двох середньоосвітніх шкіл м. Тернополя віком 9-17 років із метою встановлення частоти надлишкової маси тіла, ожиріння та метаболічного синдрому і простеження клінічних та фено- типічних особливостей цих патологічних станів серед дитячого населення. Отримані результати показали, що частота надлишкової маси тіла серед школярів Тернополя становить<br />11.1 %, а ожиріння - у 4,8 % (11,8 - в дівчат і 14,8 % - у хлопців), хлопці тричі частіше хворіють на ожиріння і в 1,4 раза з надлишковою масою тіла, ніж дівчата, а частота дефіциту маси тіла не залежить від статі. У пубертаті хлопці втричі частіше хворіють на ожирінням: 7,3 % хлопці та 2,3 % дівчата (F=0,523, р&lt;0,05) і більш схильні до надлишкової маси (11,1 та 6,4 % відповідно). Абдомінальне ожиріння загалом серед дітей і підлітків зафіксовано у 4 % хлопців та вдвічі рідше (1,9 %) у дівчат. Поширеність абдомінального ожиріння (як маркера метаболічного синдрому) серед школярів з надлишковою масою становить 19,3 % серед обстежениххлопчиків і 18,5 % серед дівчат. Між показниками АТ та ІМТ існує пряма залежність, більш виражена у хлопців, ніж у дівчат. Кожен другий хлопець з ожирінням має лабільну АГ, а серед дівчаток з ожирінням у 50 % фіксується нормальний АТ, і лише кожна шоста має передгіпертензію.<br />КЛИНИЧЕСКИЕ И ФЕНОТИПИЧЕСКИЕ ПАТТЕРНЫ У ПОДРОСТКОВ С ИЗБЫТОЧНЫМ ВЕСОМ ТЕЛА И ОЖИРЕНИЕМ - В статье приведены результаты эпидемиологического исследования 540 школьников двух среднеобразовательных школ г. Тернополя возрастом 9-17 лет с целью установления частоты избыточного веса тела, ожирения и метаболического синдрома и прослеживания клинических и фенотипических особенностей этих патологических состояний среди детского населения. Полученные результаты показали, что частота избыточного веса тела среди школьников г. Тернополя составляет 11,1 %, а ожирение - в 4,8 % (11,8 - у девочек и 14,8 % - у мальчиков), мальчики трижды чаще болеют ожирением и в 1,4 раза чаще избыточным весом тела, чем девочки, а частота дефицита веса тела не зависит от пола. В пубертате ребята втрое чаще болеют ожирением: 7,3 % юноши и 2,3 % девушки (F=0,523, р&lt;0,05) и более склонны к избыточному весу (11,1 % и 6,4 % соответственно). Абдоминальное ожирение в целом среди детей и подростков зафиксировано в 4 % ребят и вдвое реже (1,9 %) у девушек. Распространенность абдоминального ожирения (как маркера метаболического синдрома) среди школьников с избыточным весом составляет 19,3 % среди обследованных мальчиков и 18,5 % среди девушек. Между показателями АД и ИМТ существует прямая зависимость более выражена у ребят, чем у девушек. Каждый второй парень с ожирением имеет лабильную АГ, а среди девушек с ожирением в 50 % фиксируется нормальное АД, и лишь каждая шестая имеет передгипер- тензию.<br />CLINICALAND PHENOTYPIC PATTERNS IN SCHOOLCHILDREN WITH OVERWEIGHT AND OBESITY - In the article has presented the results ot epidemiological studies ot the trequency ot overweight, obesity and metabolic syndrome among 540 schoolchildren in Ternopil city 9-17 years old. The aim is to determine the incidence ot overweight, obesity, metabolic syndrome and hypertension among Ternopil schoolchildren and to trace clinical and phenotypic teatures otthese pathological conditions among children. The results showed that the incidence ot overweight among schoolchildren is<br />11.1 % and obesity - 4.8 % (11.8 % girls and 14.8 % boys). In<br />prepubertal boys three times more often obesity develops and 1.4 times more often overweight develops than in girls, and frequency of underweight is independent of gender. In pubertal boys three times more often obesity develops: 7.3 % of boys and 2.3 % of girls (F = 0.523, p&lt;0.05) and more often overweight (11.1 and 6.4 % respectively). Abdominal obesity in general among children and adolescents recorded in 4 % of boys and half less (1.9 %) in girls. The prevalence of abdominal obesity (as a marker of metabolic syndrome) among overweight school children is 19.3 % of the examined boys and 18.5 % of girls. Between BMI and blood pressure values a direct relationship is more pronounced in boys than in girls. Every second obese guy has labile hypertension and among obese girls in the 50 % recorded normal blood pressure, and only each sixth girl has high normal blood pressure.<br />Ключові слова: поширеність ожиріння, надлишкова маса, метаболічний синдром, школярі.<br />Ключевые слова: распространенность ожирения, избыточный вес, метаболический синдром, школьники.<br />Key words: prevalence of obesity, overweight, metabolic syndrome, schoolchildren.


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