scholarly journals Characterization of the articular disc and mandibular condyle in healthy individuals and individuals with temporomandibular disorders in relation with several symptoms—ultrasound study

2021 ◽  
Vol 31 (Supplement_2) ◽  
Author(s):  
Alexandra André ◽  
João Paulo Figueiredo ◽  
Ana Silva
Keyword(s):  
Mandibular Condyle ◽  
Ethics Committees ◽  
Control Group ◽  
Articular Disc ◽  
Healthy Individuals ◽  
Open Mouth ◽  
Validated Questionnaire ◽  
Ultrasound Study ◽  
The Right

Abstract Background Evaluate dimension of the articular disc and condyle between volunteers and patients with temporomandibular joint (TMJ) disorders previously diagnosed. Understand the symptoms that TMJ can promote using the ultrasound modality. Approved ethics committees of IPC. Methods Sample n = 36, ages [18–45], control group (CG) (n = 20), pathologic group (PG)(n = 16). Images were acquired with US with a linear B-scan (10 MHz) in a transverse plane. Bilateral TMJ study was done with open and closed mouth. A validated questionnaire was done. Results Dimension of the right disc was 0.072 ± 0.021 cm to PG and 0.090 ± 0.018 cm to CG with open mouth. Close mouth was 0.082 ± 0.024 cm to the PG and 0.100 ± 0.014 cm to the CG.The results to the condyle were 0.0351 ± 0.044 cm to PG and 0.378 ± 0.043 cm to CG. To the left side the alterations were in the dimension of the articular disc, the PG with open mouth, 079 ± 0.024 cm and close mouth 0.081 ± 0.019 cm. Significant differences in the symptoms between groups were observed. Symptoms revel that 62.5% have headache and 87% present noise/crackle in the masticatory. Conclusions Right side the PG had reduced articular disc and condyle dimensions when compared to the healthy group. This study shows the possible differences in the articular disc and condyle in PG and CG, also permitted study the TMJ disorders in real time with accuracy. The questionnaire it was possible to determine the main symptoms of the TMJ disorders. These disorders are in relation with de alterations dimension of the articular disc.

scholarly journals Characterization of a Novel Model of Overuse-Induced Calcific Achilles Tendinopathy in Mice: Contralateral Tendinopathy Following Unilateral Tenotomy

2017 ◽  
Author(s):  
Liang Wang ◽  
Jie Zhang ◽  
Gang-hui Yin ◽  
Zhong-min Zhang ◽  
Tian-yu Chen ◽  
...  
Keyword(s):  
Achilles Tendon ◽  
Underlying Mechanism ◽  
Biomechanical Properties ◽  
Achilles Tendinopathy ◽  
Control Group ◽  
Human Beings ◽  
Achilles Tenotomy ◽  
The Right ◽  
Experimental Group

AbstractObjectiveTo develop a simple but reproducible overuse induced animal model of Achilles tendinopathy in mice for better understanding the underlying mechanism and prevention of calcific Achilles tendinopathy.Methods80 C57/B6 mice (8-9 weeks old) were employed and randomly divided into control group and experimental group. Unilateral Achilles tenotomy was performed on the right hindlimb of experiment group. After 12 weeks, the onset of Achilles tedinopathy in the contralateral Achilles tendon was determined by radiological assessment, histological analysis, electron microscopy observation and biomechanical test.ResultsThe onset of calcific Achilles tendinopathy in contralateral Achilles tendon was confirmed after 12 weeks unilateral tenotomy. The contralateral Achilles tendon of experimental group was characterized as hypercelluarity, neovascularization and fused collagen fiber disarrangement, compared to the control group. Importantly, intratendon endochondral ossification and calcaneus deformity was featured in contralateral Achilles tendon. Additionally, poor biomechanical properties in the contralateral Achilles tendon revealed the incidence of Achilles tedinopathy.ConclusionWe hereby introduce a novel simple but reproducible spontaneous contralateral calcific Achilles tendinopathy model in mice, which represents the overuse conditions during the tendinopathy development in human-beings. It should be a useful tool to further study the underlying pathogenesis of calcific Achilles tendinopathy.

Characterizing ventricular mechanics and energetics following repeated coronary microembolization

1997 ◽  
Vol 272 (1) ◽  
pp. H186-H194 ◽  
Author(s):  
K. Todaka ◽  
D. Leibowitz ◽  
S. Homma ◽  
P. E. Fisher ◽  
C. Derosa ◽  
...  
Keyword(s):  
Diastolic Pressure ◽  
Systolic Pressure ◽  
Control Group ◽  
Myocardial Mechanics ◽  
Ventricular Mechanics ◽  
Volume Relation ◽  
The Right ◽  
Important Characterization ◽  
The Relationship

Myocardial mechanics and energetics were investigated in an animal model of moderate chronic heart failure (CHF) created by repeated coronary microembolizations in six dogs. The final fractional area change was 34 +/- 4%. Hearts of these animals were isolated and cross-perfused, and balloons were placed in the left ventricle (LV). Chamber contractile state was markedly depressed in embolized hearts as assessed by the slope (Ees 2.74 +/- 0.49 vs. 4.00 +/- 1.18 mmHg/ml, P < 0.01) and volume axis intercept (V: 8.7 +/- 5.9 vs. 1.0 +/- 3.2 ml, P < 0.01) of end-systolic pressure-volume relation compared with a group of six normal dogs. The end-diastolic pressure-volume relation of embolized hearts was shifted to the right, indicating a dilation of the LV. However, systolic and diastolic stress strain relationships were similar in the two groups, suggesting that the average myocardial properties of the embolized hearts are similar to those of normal hearts. The relationship between oxygen consumption and pressure-volume area in embolized hearts had smaller intercept (2.98 +/- 0.44 vs 3.92 +/- 0.39 x 10(-2) ml O2.beat-1.100 g LV-1, P < 0.01) compared with the control group, with no change in the slope. These results contrast with previous findings in pacing CHF and serve as an important characterization of ventricular properties in this model of CHF from different etiology.

scholarly journals Comparison Between Strength of Muscles Rotating the Knee in Healthy Individuals and Patients one Year after an ACL Reconstruction

2014 ◽  
Vol 2 (11_suppl3) ◽  
pp. 2325967114S0014
Author(s):  
Marcın Popieluch ◽  
Robert Śmigıelski ◽  
Darıusz Straszewski ◽  
Marcın Plenzler ◽  
Mıchał Stanıszewski
Keyword(s):  
Muscle Strength ◽  
Internal Rotation ◽  
Acl Reconstruction ◽  
Lower Leg ◽  
Control Group ◽  
Special Device ◽  
Healthy Individuals ◽  
Static State ◽  
Significant Difference ◽  
The Right

Objectives: In this study we have made an attempt to establish torque value of the muscles rotating the knee of patients who had ruptured their ACLs during an amateur football practise on an artificial turf. In this study we presented biomechanical research on torques of muscles responsible for internal and external rotation of the lower leg. We presented a method whereby it is possible to measure the muscle strength before and after the ACL rupture but also during the process of rehabilitation and after its finish. The available literature on measurements of torque of the knee is quite extensive though it mainly describes torques of muscles flexing and extending the joint. In Polish literature there is scarcity of studies focused on torques of muscles rotating the knee. In foreign literature there is an increasing emphasis on the role of lower leg rotation, as the element greatly impacting, for instance, the position of the foot. Methods: The study presents results of 22 patients and 50 healthy individuals (not practising any particular sport regularly) being the control group. All patients had their ACLs reconstructed using the double-bundle technique. The material for the graft was obtained from the hamstrings. The aim was to measure the maximal torque of the muscles responsible for external and internal rotation of the knee (lower leg in a static state using a special device). The device allowed measurement of the torque of muscles rotating the lower leg in its axis by stabilizing the ankle with special emphasis on foot mounting (stabilization of footwear). The special device was connected to a PC with CPS/HMF software. The software enabled observation and recording of increase in the value of the torque until it reached its maximum. The measurements were taken in two knee positions: 30 degrees and 90 degrees flexion. Results: The result were analyzed statistically, means and SDs were calculated. Only right-legged subjects were included in the analysis. The Shapiro-Wilk test was used to test normality of the distribution. Some of the data did not have a normal distribution so in order to compare results of different groups a non-parametric Mann–Whitney U test was used. The groups differed significantly in terms of age (p=0.001), did not differ in terms of body height (p=0.529) or mass (p=0.233). Statistically significant differences (p<0.001) were marked by an asterix symbol (*). Each measurement of the left and right leg was also compared between the groups. The Kruskal–Wallis one-way analysis of variance by ranks was used and significant differences were those with p<0.001. When analyzing it has been noted that there was a statistically significant difference (p<0.001) between the torque value of muscles responsible for internal rotation (S40) when examining the right limb (after ACL reconstruction) in both groups. Significant differences were observed in all starting positions, as well as in both degrees of flexion – 30 and 900. Deficit of muscle strength on the right side – the injured one – when compared to the left was sometimes as high as 30%. Conclusion: 1. Near 30% deficit of strength of muscles responsible for internal rotation of the knee indicates that the knee is rotationally unstable after a year from the surgery. 2. Based on the fact that using the hamstrings tendons – responsible for internal rotation of the knee – in order to reconstruct the ACL, poses a risk of rotational instability of the joint for as long as a year after the procedure, the rehabilitation protocol for such patients should be adjusted or completely changed.

scholarly journals Análise microscópica na articulação temporomandibular a partir da mudança de direção do vetor de força da mandíbula em relação à base do crânio : estudo experimental em coelhos (Oryctolagus cuniculus l.)

2021 ◽  
Vol 40 (2) ◽  
pp. 66-72
Author(s):  
Deise Ponzoni ◽  
Edela Puricelli
Keyword(s):  
Temporal Bone ◽  
Oryctolagus Cuniculus ◽  
Mandibular Condyle ◽  
Structure And Function ◽  
Control Group ◽  
Articular Disc ◽  
Direction Change ◽  
The Moment ◽  
And Function ◽  
Experimental Group

The correlation between TMJ's growing, structure and function is consensual in the specialized literature. Until the moment, the little knowledge about post-birth changes are studied by observation of condylar growth and disc reestructuration. In an experimental model in rabbits (Oryctolagus cuniculus 1.), it was observed tecidual alterations of the TMJ's components — mandibular condyle, articular disc and temporal bone, face to a direction change of mandibular power axis, which has the incidence upon these structures. Twentyfour rabbit were divided in four groups. Two of each group formed a control group. Four experimental periods were established 15, 30, 60 and 90 days. The animals from the experimental group were submitted to surgical procedure involving the mandible right side, changing the direction of mandibular power axis, which has incidence in the TMJ. Histological observations of TMJ in the control group, at different times, the growth and development of this structure were showed, compatible to the normality. At experimental group, the change of mandibular power axis caused alteration of the mandibular condyle and the discal structure. Significative responses at temporal bone were observed too, as a process of osseous modelation, suggestive of growth of this cranial structure.

Correlation of Metabolic Risk Factors with Sessile Serrated Lesions

2020 ◽  
Vol 29 (2) ◽  
pp. 175-179
Author(s):  
Melania Macarie ◽  
Simona Bataga ◽  
Simona Mocan ◽  
Monica Pantea ◽  
Razvan Opaschi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Statistical Significance ◽  
Interval Cancer ◽  
Metabolic Risk Factors ◽  
Control Group ◽  
Anatomical Site ◽  
Metabolic Risk ◽  
Right Colon ◽  
Serrated Lesions ◽  
The Right

Background and Aims: The importance of sessile serrated lesions (SSLs) in the pathogenesis of colorectal carcinoma has been recently established. These are supposed to cause the so-called “interval cancer”, having a rapidly progressive growth and being difficult to detect and to obtain an endoscopic complete resection. We aimed to establish the most important metabolic risk factors for sessile serrated lesions. Methods: We performed a retrospective case-control study, on a series of 2918 consecutive patients who underwent colonoscopy in Gastroenterology and Endoscopy Unit, County Clinical Emergency Hospital, Târgu-Mureș, Romania between 1 st of January 2015-31 th of December 2017. In order to evaluate the metabolic risk factors for polyps’ development, enrolled participants were stratified in two groups, a study group, 33 patients with SSLs lesions, and a control group, 138 patients with adenomatous polyps, selected by systematic sampling for age and anatomical site. Independent variables investigated were: gender, smoking, alcohol consumption, obesity, arterial hypertension, diabetes, hypercholesterolemia, hypertriglyceridemia, hyperuricemia, nonalcoholic liver disease. Results: For SSLs the most common encountered localization was the right colon in 30.55% of cases. By comparative bivariate analysis between SSLs group and control group, it was observed that hypertension (p=0.03, OR 2.33, 95 %CI 1.03-5.24), obesity (p=0.03, OR 2.61, 95 %CI 1.08-6.30), hyperuricemia (p=0.04, OR 2.72, 95 %CI 1.28-7.55), high cholesterol (p=0.002, OR 3.42; 95 %CI 1.48-7.87), and high triglycerides level (p=0.0006, OR 5.75; 95 %CI 1.92-17.2) were statistically associated with SSLs development. By multivariate analysis hypertension and hypertriglyceridemia retained statistical significance. Conclusions: Our study showed that the highest prevalence of SSLs was in the right colon and hypertension and increased triglycerides levels were associated with the risk of SSLs development. These risk factors are easy to detect in clinical practice and may help identifying groups with high risk for colorectal cancer, where screening is recommended.

Early Predictive Biochemical, Electrocardiographic and Echocardiographic Markers for Cardiac Damage in Patients with Pulmonic Silicosis

2019 ◽  
Vol 70 (1) ◽  
pp. 63-68 ◽  
Author(s):  
Venera Cristina Dinescu ◽  
Ileana Puiu ◽  
Sorin Nicolae Dinescu ◽  
Diana Rodica Tudorascu ◽  
Elena Catalina Bica ◽  
...  
Keyword(s):  
Heart Disease ◽  
Right Ventricle ◽  
Control Group ◽  
Cardiac Damage ◽  
Right Heart ◽  
Pulmonary Heart Disease ◽  
Upper Limit ◽  
Echocardiographic Parameters ◽  
The Right ◽  
Chronic Pulmonary Heart Disease

The aim of this study was to identify correlations between electrocardiographic and echocardiographic changes in patients with silicosis prior to the occurrence of chronic pulmonary heart disease. We conducted a prospective, descriptive, analytical study, in which we included a group of 67 patients consecutively admitted to the Health Promotion and Occupational Medicine Clinic between December 2016 and January 2018, aged 47 to 78 years.There was a biochemical and electrocardiographic evaluation for each patient as well as a right ventricle echocardiographic evaluation (diameters, volumes, function). A control group, including 25 patients with benign minor diseases that required a cardiologist consultation, was also used. From the electrocardiographic point of view, slight changes were observed regarding the waves of electrical activity of the right ventricle. Taking into account the degree of ventilatory dysfunction (depending on FEV1), changes in right heart echocardiographic parameters were identified. Thus, in what the most important right ventricular parameters, including the tricuspid annular plane systolic excursion (TAPSE) or the RV index of myocardial performance (RVMPI) were concerned, values at the upper limit of normality were recorded in most patients with moderate and severe ventilatory dysfunction. Values of echocardiographic parameters of the right heart at the upper limit of normality, correlated with the degree of ventilatory dysfunction, are early markers for cardiovascular damage in patients with pulmonary silicosis prior to the occurrence of chronic pulmonary heart disease also known ascor pulmonale.

Evaluation of Ovaries in Patients with Polycystic Ovary Syndrome using Shear Wave Elastography

2020 ◽  
Vol 16 (5) ◽  
pp. 578-583
Author(s):  
Aysegul Altunkeser ◽  
Zeynep Ozturk Inal ◽  
Nahide Baran
Keyword(s):  
Shear Wave ◽  
Large Scale ◽  
Polycystic Ovary ◽  
Shear Wave Elastography ◽  
Left Ovary ◽  
Control Group ◽  
Tissue Elasticity ◽  
Group I ◽  
Pcos Group ◽  
The Right

Background: Shear wave electrography (SWE) is a novel non-invasive imaging technique which demonstrate tissue elasticity. Recent research evaluating the elasticity properties of normal and pathological tissues emphasize the diagnostic importance of this technique. Aims: Polycystic ovarian syndrome (PCOS), which is characterized by menstrual irregularity, hyperandrogenism, and polycystic overgrowth, may cause infertility. The aim of this study was to evaluate the elasticity of ovaries in patients with PCOS using SWE. Methods: 66 patients diagnosed with PCOS according to the Rotterdam criteria (PCOS = group I) and 72 patients with non-PCOS (Control = group II), were included in the study. Demographic and clinical characteristics of the participants were recorded. Ovarian elasticity was assessed in all patients with SWE, and speed values were obtained from the ovaries. The elasticity of the ovaries was compared between the two groups. Results: While there were statistically significant differences between the groups in body mass index (BMI), right and left ovarian volumes, luteinizing hormone and testosterone levels (p<0.05), no significant differences were found between groups I and II in the velocity (for the right ovary 3.89±1.81 vs. 2.93±0.72, p=0.301; for the left ovary 2.88±0.65 vs. 2.95±0.80, p=0.577) and elastography (for the right ovary 36.62±17.78 vs. 36.79±14.32, p=0.3952; for the left ovary 36.56±14.15 vs. 36.26±15.10, p=0.903) values, respectively. Conclusion: We could not obtain different velocity and elastography values from the ovaries of the patients with PCOS using SWE. Therefore, further large-scale studies are needed to elucidate this issue.

Comparison of the Aditus ad Antrum Diameter on CT between Patients with Chronic Otitis Media and Healthy Individuals

2019 ◽  
Vol 15 (10) ◽  
pp. 990-993 ◽  
Author(s):  
Elif Gündoğdu ◽  
Uğur Toprak
Keyword(s):  
Computed Tomography ◽  
Otitis Media ◽  
Middle Ear ◽  
Healthy Subjects ◽  
Normal Values ◽  
Chronic Otitis Media ◽  
Healthy Individuals ◽  
Inner Diameter ◽  
Male Patients ◽  
The Right

Background: The middle ear cavity is ventilated through the aditus ad antrum. Aditus blockage contributes to the pathology of otitis media. Objective: To determine the normal values of the aditus ad antrum diameter on computed tomography and to investigate its relationship with chronic otitis media and related pathologies (tympanosclerosis and myringosclerosis). Methods: The temporal CT images of 162 individuals were evaluated retrospectively. In the axial sections, the inner diameter of the aditus was measured at the narrowest point at the cortex. The differences in diameter were compared between diseased and healthy ears. Results: In healthy individuals, the diameter was narrower in women. There was no difference between the right and left ears in healthy subjects. No correlation was found between age and diameter. In male patients with myringosclerosis, the diameter was slightly narrower on both sides but more marked on the left. In female patients with myringosclerosis, the diameter in both ears was slightly narrower. In cases of otitis media and tympanosclerosis, the diameter was less than that of healthy individuals, despite the lack of statistically significant result in all cases. Conclusion: The aditus ad antrum was narrower in diseased ears, indicating that a blocked aditus may contribute to the development of otitis media, as well as mucosal diseases.

Prevalence of Toxoplasma gondii and Toxocara canis among Myositis Patients in Southwest of Iran

2019 ◽  
Vol 20 ◽  
Author(s):  
Jasem Saki ◽  
Karim Mowla ◽  
Reza Arjmand ◽  
Forough Kazemi ◽  
Somayeh Fallahizadeh
Keyword(s):  
Toxoplasma Gondii ◽  
Nested Pcr ◽  
Healthy Subjects ◽  
Toxocara Canis ◽  
Control Group ◽  
Igg Antibodies ◽  
Healthy Individuals ◽  
High Prevalence ◽  
Acute Toxoplasmosis ◽  
Southwest Of Iran

Introduction: Parasitic myositis is caused by some parasites such as T. gondii and T. canis. So, the aim of the study was to evaluate the prevalence T. gondii and T. canis in patients with myositis and healthy individuals. Methods: A total of 108 samples were randomly selected as the control (54 healthy individuals) and test (54 myositis patients) groups. IgG and IgM antibodies against T. gondii and IgG antibodies against T. canis were measured by the ELISA. The detection of chronic and acute toxoplasmosis was performed by the ELISA IgG avidity. The presence of T. gondii in blood was evaluated by the nested-PCR. Results: Of 108, 33 (30.6%) cases were detected positive for IgG against T. gondii that 19 (35.2%) and 14 (25.9%) were observed in myositis patients and healthy individuals, respectively (P=0.296). Of 19 positive cases, 12 (63.2%) and 7 (36.8%) cases were detected as chronic and acute toxoplasmosis, respectively, while, all positive cases in the control group had chronic toxoplasmosis (P=0.013). One (1.9%) sample was detected positive for anti- Toxoplasma gondii IgM and two (3.7%) samples were found positive for IgG against T. canis by the ELISA that these positive cases were observed only in myositis patients (P=1.000 P=0.495, respectively). B1 T. gondii gene was amplified in 12 (63.2%) and 1 (7.1%) in myositis patients and healthy subjects (P=0.001). Conclusions: Our findings showed that there was a relatively high prevalence of acute toxoplasmosis in myositis patients in comparison with the control subjects in southwest of Iran.

Força dos Músculos Rotadores do Ombro em Indivíduos Saudáveis/ Rotator Cuff Muscle Strength in Healthy Individuals

1970 ◽  
Vol 1 (1) ◽  
pp. 78-82
Author(s):  
Paulo José Oliveira Cortez ◽  
José Elias Tomazini ◽  
Mauro Gonçalves
Keyword(s):  
Rotator Cuff ◽  
Muscle Strength ◽  
Internal Rotation ◽  
Upper Limb ◽  
Statistical Difference ◽  
External Rotation ◽  
Healthy Individuals ◽  
Average Strength ◽  
Strength Tests ◽  
The Right

Introdução: A diminuição da capacidade de exercer esforços por parte dos músculos rotadores pode criar uma variedade de problemas. O conhecimento preciso do nível de força muscular de um indivíduo é importante, tanto para a avaliação da capacidade funcional ocupacional, como para uma apropriada prescrição de exercícios atléticos e de reabilitação. Percebe-se escassez de informação sobre as articulações do ombro, bem como os fatores envolvidos na força muscular dessa região. O objetivo deste estudo foi comparar a força gerada pelos músculos do manguito rotador entre o membro superior direito e o membro superior esquerdo em indivíduos saudáveis. Métodos: Participaram do estudo 22 sujeitos do sexo masculino, com idade de 18 e 19 anos, militares, saudáveis e sem história clínica de patologia ortopédica ou qualquer tipo de lesão no sistema musculoesquelético. Foram aplicados dois testes de força: Rotação Interna e Rotação Externa. Resultado : A força média de rotação interna no membro superior direito (MSD) foi maior que a força média de rotação interna no membro superior esquerdo (MSE) (p=0,723) e a força de rotação externa no MSD foi menor que a força média de rotação externa no MSE (p=0,788). Não houve diferença estatística na comparação dos valores de força de todos os testes de força isométrica. Conclusão: Para amostra estudada e metodologia utilizada na avaliação da força muscular, não houve diferença estatística na comparação da força gerada pelos músculos do manguito rotador do membro superior direito e do membro superior esquerdo.Rotator Cuff Muscle Strength in Healthy Individuals Introduction: Decreased ability to exert efforts by the rotator muscles can create a variety of problems. The precise knowledge of the level of muscular strength of an individual is important for both the functional capacity evaluation for occupational as an appropriate exercise prescription and rehabilitation of athletic. It is perceived scarcity of information on the shoulder joints as well as factors involved in muscle strength in this region. Objective: Develop a device for measuring the strength generated by the muscles of the upper limbs and the verification of efficiency and adaptability of this device through a comparative study of muscle strength in healthy subjects. Methods: The study included 22 male subjects, aged 18 and 19 years, military personnel, body mass between 57.7 and 93 kg (71.8 ± 9.45 kg) and height between 1.67 and 1.90 m (1.75 ± 0.06 m), healthy and without a history of orthopaedic disease or any kind of damage to the musculoskeletal system. Three strength tests were applied: Internal Rotation and External Rotation. For each type of effort three maximum voluntary contractions were required for 10 seconds, with an interval of 30 seconds between each contraction.  Results: Internal rotation in the right upper limb (RUL) was higher than the average strength of internal rotation in the left upper limb (LUL) (p = 0, 723) and the external rotation strength in RUL was lower than the average strength of external rotation in the LUL (p=0,788).  No statistical difference in comparing the strength values of all isometric strength tests. Conclusion: For sample and methodology used to assess muscle strength, there was no statistical difference in comparing the force generated by the muscles of the rotator cuff of the right and left upper limb.

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