scholarly journals Applying a One Health approach to inter- and trans-disciplinary research on antimicrobial resistance

2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
T Falkenberg
Keyword(s):  
Antimicrobial Resistance ◽  
Graduate School ◽  
One Health ◽  
Animal Health ◽  
Urban Transformation ◽  
Health Issues ◽  
Close Collaboration ◽  
Enabling Factors ◽  
Health Crisis ◽  
The One

Abstract This presentation will focus on the value and process as well as the opportunities and challenges of applying a One Health approach to conduct inter- and trans-disciplinary research on antimicrobial resistance (AMR) based on experiences in the Forschungskolleg (graduate school) “One Health and urban transformation” (https://www.zef.de/onehealth.html), hosted at the Center for Development Research in Bonn. The One Health approach acknowledges that human health is inextricably intertwined with animal health and the environment and that solutions to health issues can only be achieved by close collaboration and integrated approaches of those three domains. In the complex context of AMR, One Health is often mentioned as one promising way forward for managing and mitigating the approaching health crisis due to its inherent holistic and interdisciplinary nature. The presentation will provide an overview of inter- and trans-disciplinary research around One Health and AMR from the Forschungskolleg thereby exploring enabling factors and obstacles encountered.

scholarly journals ANTIMICROBIAL RESISTANCE PROGRAMS IN THE EUROPEAN UNION

2018 ◽  
Vol 6 ◽  
pp. 978-985
Author(s):  
Ana Maria Zorlescu ◽  
Stelian Baraitareanu ◽  
Doina Danes
Keyword(s):  
European Union ◽  
Antimicrobial Resistance ◽  
One Health ◽  
Action Plan ◽  
Animal Health ◽  
Good Practice ◽  
The European Union ◽  
Member States ◽  
Animal Populations ◽  
The One

INTRODUCTION: Antimicrobial resistance is one of the topical issues that is part of the “One Health” concept with implications for animal health, human health, and even environmental “health”. At the European Commission (EC) level, legislation has been issued for the monitoring of antimicrobial resistance and these rules are applicable by each Member State (MS). For the proper implementation of the above legislation, audits are carried out in Member States that have developed programs on antimicrobial resistance that go beyond the EC's requests.OBJECTIVES: The aim of the study was the analysis of existing data reports, legislation and recommendations on antimicrobial resistance through which surveillance and monitoring is carried out in the European Union (EU).  METHODS: The audit reports issued between 2015 and 2017 by the Food Veterinary Office (FVO), as well as the articles and studies issued by the EC through the antimicrobial resistance institutes were analysed.RESULTS: The FVO conducted audits to “evaluate the monitoring and reporting of antimicrobial resistance in zoonotic and commensal bacteria in certain food-producing animal populations and food” in 12 MS, and audits to “gather information on the prudent use of antimicrobials in animals” in 8 MS. These are countries that have very well implemented the EC's requests and included the “One Health” perspective in antimicrobial resistance programs. Some Member States have risk management strategies for reducing antimicrobial resistance for more than 20 years. They have carried out research projects on antimicrobial resistance. There is an action plan on antimicrobial resistance at the EC level, but their implementation and understanding up to the level of all actors involved in this issue varies from MS to MS. Antimicrobial resistance in the animal population is a topical issue, notoriety among the actors involved, as well as an interdisciplinary problem with indirect results. The same principle of antimicrobial resistance in animals is applicable to humans and the environment as such, this problem can be embedded in the concept of “One Health”. The overall objective of the MS is to generate knowledge and tools to “combat” antimicrobial resistance in animals, humans and even the environment.CONCLUSION: As a conclusion, in order to improve and optimize antimicrobial resistance programs, a “good practice guide” can be achieved by MS with extensive experience in this area, to be used by MS with a more precarious application and over time to harmonize antimicrobial resistance programs within the EU.

scholarly journals Humans, Animals, Food and Environment: One Health Approach against Global Antimicrobial Resistance

Antibiotics ◽  
2020 ◽  
Vol 9 (6) ◽  
pp. 346
Author(s):  
Marcello Iriti ◽  
Sara Vitalini ◽  
Elena Maria Varoni
Keyword(s):  
Public Health ◽  
Antimicrobial Resistance ◽  
One Health ◽  
Animal Health ◽  
Global Public Health ◽  
Antimicrobial Drugs ◽  
Potential Source ◽  
Antibiotic Drugs ◽  
Hospital Stays ◽  
The One

Antimicrobial resistance represents one of the most relevant threats to global public health and food security, affecting anyone, of any age, in any country and is responsible for longer hospital stays, higher medical costs and increased mortality. Resistant microorganisms are present in humans, animals, food and the environment, and, therefore, the One Health approach is very promising to counteract antimicrobial resistance, since human health and animal health are connected to each other and with the environment and the latter a potential source of resistant microorganisms. In this context, the need for novel antimicrobial drugs has stimulated the exploration of plant products as a source of novel phytotherapeutics able to reverse antimicrobial resistance when used in combination with conventional antibiotic drugs.

73 Antimicrobial Resistance, Agriculture, and the One Health Continuum

2021 ◽  
Vol 99 (Supplement_3) ◽  
pp. 40-40
Author(s):  
Ed Topp
Keyword(s):  
Antimicrobial Resistance ◽  
Direct Contact ◽  
One Health ◽  
Animal Health ◽  
Health Concern ◽  
Health And Wellness ◽  
Transdisciplinary Approach ◽  
Health Concept ◽  
The One

Abstract The One Health concept specifies that the microbiomes of humans and animals are connected, both through direct contact, and indirectly through the environment. Managing the flow of microorganisms of human or animal health concern across the One Health continuum requires a transdisciplinary approach to address problems at the intersection of people, animals, and their environments. This presentation will use the management of antimicrobial resistance as an example of how a One Health approach can identify and develop solutions to improve the health and wellness of people, animals, and the environment.

Antimicrobial stewardship through a one health lens

2016 ◽  
Vol 21 (3) ◽  
pp. 114-130 ◽  
Author(s):  
Marisa Anne D'Angeli ◽  
Joe B. Baker ◽  
Douglas R. Call ◽  
Margaret A. Davis ◽  
Kelly J. Kauber ◽  
...  
Keyword(s):  
Antimicrobial Stewardship ◽  
One Health ◽  
Work Group ◽  
Animal Health ◽  
Antibiotic Use ◽  
Washington State ◽  
Resistant Bacteria ◽  
Health Crisis ◽  
Content Type ◽  
The One

Purpose – Antibiotic resistance (AR) is a global health crisis that is attracting focussed attention from healthcare, public health, governmental agencies, the public, and food producers. The purpose of this paper is to describe the work in Washington State to combat resistance and promote antimicrobial stewardship from a one health perspective. Design/methodology/approach – In 2014, the Washington State Department of Health convened a One Health Steering Committee and two workgroups to focus on AR, the One Health Antimicrobial Stewardship work group and the One Health Antimicrobial Resistance Surveillance work group. The group organized educational sessions to establish a basic understanding of epidemiological factors that contribute to resistance, including antibiotic use, transmission of resistant bacteria, and environmental contamination with resistant bacteria and antibiotic residues. Findings – The authors describe the varied uses of antibiotics; efforts to promote stewardship in human, and animal health, including examples from the USA and Europe; economic factors that promote use of antibiotics in animal agriculture; and efforts, products and next steps of the workgroups. Originality/value – In Washington, human, animal and environmental health experts are working collaboratively to address resistance from a one health perspective. The authors are establishing a multi-species resistance database that will allow tracking resistance trends in the region. Gaps include measurement of antibiotic use in humans and animals; integrated resistance surveillance information; and funding for AR and animal health research.

scholarly journals Abuse of Antibiotic Treatment in a one Health Context

2021 ◽  
Author(s):  
S M Nazmuz Sakib
Keyword(s):  
Antimicrobial Resistance ◽  
Antibiotic Treatment ◽  
One Health ◽  
Animal Health ◽  
Global Scale ◽  
Chronic Illnesses ◽  
Environmental Sciences ◽  
Health Security ◽  
Human Animal ◽  
The One

A considerable rise in the spread of infectious agents has been documented during the last decade. With the expansion and appearance of zoonoses, epizootics, and epidemics, the threat of pandemics has grown increasingly serious (Destoumieux-Garzón et al., 2018). Antimicrobial resistance, pollution, and the emergence of multifactorial and chronic illnesses have all posed a danger to human and animal health. This brought attention to the growing globalization of health hazards, as well as the role of the human–animal–ecosystem interaction in pathogen development and emergence (Destoumieux-Garzón et al., 2018).In response to trends observed in the recent past a thorough interpretation of disease dynamics and to drive public policy, a deeper understanding of the causes and effects of particular human activities, lifestyles, and behaviors in ecosystems is critical. Health security, as a global benefit, must be understood on a global scale and from a global and crosscutting viewpoint, including human, animal, plant, ecosystem, and biodiversity health (McEwen and Collignon, 2018).This study is aimed at establishing antibiotic treatment abuse in one health context. The study also considers how important it is to consider evolutionary, ecological, and environmental sciences in understanding the emergence and re-emergence of infectious diseases, as well as the challenges of antimicrobial resistance. Finally, the study identifies hurdles that must be overcome as well as goals that must be nurtured in order to effectively implement the "One Health" idea. The paper establishes that for the One Health idea to succeed, curb antibiotic resistance among other challenges, multidisciplinary boundaries that currently exist between veterinary and human medicine and evolutionary, ecological, and environmental sciences must be broken down and medical policies in place re-evaluated.

scholarly journals European Union funded research projects on zoonoses, evaluation of the added value of a One Health Approach

2021 ◽  
Vol 174 ◽  
Author(s):  
André Jestin ◽  
Gilles Dreyfuss ◽  
Michel Fougereau ◽  
René Houin ◽  
Hubert Laude ◽  
...  
Keyword(s):  
European Union ◽  
Antimicrobial Resistance ◽  
One Health ◽  
Animal Health ◽  
Interdisciplinary Approach ◽  
Added Value ◽  
Major Step ◽  
Joint Project ◽  
Eu Member States ◽  
The One

The One Health approach, in which feed, food, animal health, public health and contamination of the environment are considered as very closely linked, is regarded as the best way to achieve significant progress of health in these fields. The current European Union funded projects aimed to achieve a major step forward for Europe in the domains of foodborne zoonoses and antimicrobial resistance. The 6th and 7th Framework programs initiated networks, such as ERA-Net, Networks of Excellence (NoE), Joint Program initiatives (JPI), Infrastructure program. The European Joint Action (JA) aims to promote synergies among the EU Member States by developing and implementing effective One Health policies to combat the growing threat of antibiotic resistance. The One Health European Joint Project (EJP) is a large co-funded project on emerging threats, zoonoses and antimicrobial resistance. If a One Health approach has been proposed to tackle the challenges by accepting that their complexity requires interdisciplinary approach, no standardized methodologies were available for quantitative evaluation of One Health activities. The Network for Evaluation of One Health (NEOH) represents a major contribution in that field. Key Words : One health, European Networks, Human-animal interface, Zoonoses, Antimicrobial resistance, Evaluation, Added value.

scholarly journals Tick-borne zoonoses and commonly used diagnostic methods in human and veterinary medicine

2021 ◽  
Author(s):  
Andrea Springer ◽  
Antje Glass ◽  
Julia Probst ◽  
Christina Strube
Keyword(s):  
Veterinary Medicine ◽  
Diagnostic Tests ◽  
One Health ◽  
Animal Health ◽  
Diagnostic Techniques ◽  
Diagnostic Methods ◽  
Diagnostic Tools ◽  
Zoonotic Pathogens ◽  
Health Concept ◽  
The One

AbstractAround the world, human health and animal health are closely linked in terms of the One Health concept by ticks acting as vectors for zoonotic pathogens. Animals do not only maintain tick cycles but can either be clinically affected by the same tick-borne pathogens as humans and/or play a role as reservoirs or sentinel pathogen hosts. However, the relevance of different tick-borne diseases (TBDs) may vary in human vs. veterinary medicine, which is consequently reflected by the availability of human vs. veterinary diagnostic tests. Yet, as TBDs gain importance in both fields and rare zoonotic pathogens, such as Babesia spp., are increasingly identified as causes of human disease, a One Health approach regarding development of new diagnostic tools may lead to synergistic benefits. This review gives an overview on zoonotic protozoan, bacterial and viral tick-borne pathogens worldwide, discusses commonly used diagnostic techniques for TBDs, and compares commercial availability of diagnostic tests for humans vs. domestic animals, using Germany as an example, with the aim of highlighting existing gaps and opportunities for collaboration in a One Health framework.

scholarly journals Assessing Environmental Factors within the One Health Approach

Medicina ◽  
2021 ◽  
Vol 57 (3) ◽  
pp. 240
Author(s):  
Sarah Humboldt-Dachroeden ◽  
Alberto Mantovani
Keyword(s):  
Case Studies ◽  
One Health ◽  
Animal Health ◽  
Grey Literature ◽  
Aflatoxin M1 ◽  
First Case ◽  
Italian Regions ◽  
Environmental Component ◽  
Environmental Considerations ◽  
The One

Background: One Health is a comprehensive and multisectoral approach to assess and examine the health of animals, humans and the environment. However, while the One Health approach gains increasing momentum, its practical application meets hindrances. This paper investigates the environmental pillar of the One Health approach, using two case studies to highlight the integration of environmental considerations. The first case study pertains to the Danish monitoring and surveillance programme for antimicrobial resistance, DANMAP. The second case illustrates the occurrence of aflatoxin M1 (AFM1) in milk in dairy-producing ruminants in Italian regions. Method: A scientific literature search was conducted in PubMed and Web of Science to locate articles informing the two cases. Grey literature was gathered to describe the cases as well as their contexts. Results: 19 articles and 10 reports were reviewed and informed the two cases. The cases show how the environmental component influences the apparent impacts for human and animal health. The DANMAP highlights the two approaches One Health and farm to fork. The literature provides information on the comprehensiveness of the DANMAP, but highlights some shortcomings in terms of environmental considerations. The AFM1 case, the milk metabolite of the carcinogenic mycotoxin aflatoxin B1, shows that dairy products are heavily impacted by changes of the climate as well as by economic drivers. Conclusions: The two cases show that environmental conditions directly influence the onset and diffusion of hazardous factors. Climate change, treatment of soils, water and standards in slaughterhouses as well as farms can have a great impact on the health of animals, humans and the environment. Hence, it is important to include environmental considerations, for example, via engaging environmental experts and sharing data. Further case studies will help to better define the roles of environment in One Health scenarios.

scholarly journals Finding What Is Inaccessible: Antimicrobial Resistance Language Use among the One Health Domains

Antibiotics ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 385
Author(s):  
Lauren L. Wind ◽  
Jonathan S. Briganti ◽  
Anne M. Brown ◽  
Timothy P. Neher ◽  
Meghan F. Davis ◽  
...  
Keyword(s):  
Antibiotic Resistance ◽  
Open Access ◽  
Antimicrobial Resistance ◽  
Language Processing ◽  
One Health ◽  
Language Use ◽  
Language Usage ◽  
Health Domains ◽  
Accessibility Issues ◽  
The One

The success of a One Health approach to combating antimicrobial resistance (AMR) requires effective data sharing across the three One Health domains (human, animal, and environment). To investigate if there are differences in language use across the One Health domains, we examined the peer-reviewed literature using a combination of text data mining and natural language processing techniques on 20,000 open-access articles related to AMR and One Health. Evaluating AMR key term frequency from the European PubMed Collection published between 1990 and 2019 showed distinct AMR language usage within each domain and incongruent language usage across domains, with significant differences in key term usage frequencies when articles were grouped by the One Health sub-specialties (2-way ANOVA; p < 0.001). Over the 29-year period, “antibiotic resistance” and “AR” were used 18 times more than “antimicrobial resistance” and “AMR”. The discord of language use across One Health potentially weakens the effectiveness of interdisciplinary research by creating accessibility issues for researchers using search engines. This research was the first to quantify this disparate language use within One Health, which inhibits collaboration and crosstalk between domains. We suggest the following for authors publishing AMR-related research within the One Health context: (1) increase title/abstract searchability by including both antimicrobial and antibiotic resistance related search terms; (2) include “One Health” in the title/abstract; and (3) prioritize open-access publication.

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