scholarly journals Do people with rheumatoid arthritis maintain their physical activity level at treatment onset over the first year of methotrexate therapy?

Rheumatology ◽  
2021 ◽  
Author(s):  
James M Gwinnutt ◽  
Husain Alsafar ◽  
Kimme L Hyrich ◽  
Mark Lunt ◽  
Anne Barton ◽  
...  

Abstract Objectives To describe how many people with rheumatoid arthritis (RA) reduce their baseline physical activity (PA) level over the first year of methotrexate (MTX) treatment, and which factors predict this. Methods Data came from the Rheumatoid Arthritis Medication Study (RAMS), a prospective cohort of people with early RA starting MTX. Participants reported demographics and completed questionnaires at baseline, six and 12 months, including reporting the number of days per week they performed ≥20 min of PA; coded as none, low (1–3 days) or high (4–7 days). The PA levels of participants over 12 months are described. Predictors of stopping PA were assessed using multivariable logistic regression. Results In total, 1468 participants were included (median [interquartile range] age: 60 [50, 69] years; 957 [65.2%] women). At baseline, the PA levels of the people with RA were: none = 408 (27.8%), low = 518 (35.3%), high = 542 (36.9%). 80% of participants maintained some PA or began PA between assessments (baseline to 6-months = 79.3%, 6-months to 12-months = 80.7%). 24.1% of participants reduced PA and 11.3% of participants stopped performing PA between baseline and 6-months (6-months to 12 months: 22.6% and 10.2% respectively). Baseline smoking, higher disability and greater socioeconomic deprivation were associated with stopping PA. Conclusion Many people with early RA were not performing PA when starting MTX, or stopped performing PA over the first year of treatment. These people may require interventions to stay active. These interventions need to be mindful of socioeconomic barriers to PA participation.

2017 ◽  
Vol 17 (2) ◽  
pp. 62-66
Author(s):  
Nataliia Semenova ◽  
Anatolii Mahlovanyi

The objective isto establish emotional state changes among female students during the academic year regarding available physical activity.Material & methods: the study involved 65 first year femalestudents of medical college at Danylo Halytskyi Lviv National Medical University. To achieve the tasks set the study relied on the following methods: analysis and synthesis of scientific and technical literature, pedagogical observation, methods of mathematical statistics (t-Student test for independent samples), SAN method.Results: no reliable differences found when comparing indicators of activity and mood at the beginning and end of the academic year. The obtained results of the survey indicate medium and high evaluationof SAN categories at low levels of physical activity.Conclusions: state of health, activity and mood levelswere rated with middle and high scoresbyfemale students. SAN evaluation dynamics has been lowering during the academic year, and the activity level of female students was significantly lower than that ofstate of health as well as mood. The resulting index of activity level as emotional characteristic largely reflects low physical activity of female students. 


2020 ◽  
pp. 1-7
Author(s):  
Jesper Karmisholt ◽  
Allan Carlé ◽  
Stig Andersen

<b><i>Background:</i></b> Weight gain during treatment of hyperthyroidism is a frequent and for many patients unwanted outcome. With this repeated measurement study, we explored the timing of weight changes during the first year of antithyroid drug (ATD) treatment and assessed the correlation between body weight changes and changes in thyroid hormones, resting energy expenditure (REE), physical activity level, and energy efficiency. <b><i>Methods:</i></b> Patients with new onset hyperthyroidism were investigated every second month during the first year of ATD treatment. At each investigation, the following were measured: body weight, thyroid hormone concentrations, physical activity level, and daily number of steps, REE, and exercise performance. <b><i>Results:</i></b> Two men and eleven women, all sedentary, mean age 49(SD: 9.3) years were included. Significant changes after 1 year occurred for body weight (68.9–74.1 kg), thyroid hormones (free T3 [fT3] 17.5 to 4.42 pmol/L), REE (1,630–1,484 kcal/24 h), and energy efficiency at lower (50 W) workloads (16.0–17.6%). In individual patients, only REE and fT3 correlated to changes in body weight. Physical activity level did not change during treatment. <b><i>Conclusion:</i></b> In this study, treatment of hyperthyroidism was associated with marked increase in body weight in the patients. This increase correlated to a decrease in REE and only to a negligible extent to changes in energy efficiency and not at all to changes in physical activity level of daily living.


2016 ◽  
Vol 26 (76) ◽  
pp. 61-70
Author(s):  
Karol Gryko ◽  
Krzysztof Perkowski ◽  
Anna Kopiczko ◽  
Damian Włoch

Aim: The aim of the study was to evaluate the level of declared physical activity of first-year students from Jozef Pilsudski University of Physical Education in Warsaw by using the International Physical Activity Questionnaire (IPAQ). The paper presents physical activity according to the students’ chosen degree course and sex. The study also analyzes physical activity in relation to the BMI index according to the classification by the World Health Organization (WHO). Basic procedures: The group of participants comprised 190 Physical Education (n = 115) and Sports (n = 75) students. The study was conducted in November 2015 and used the short version of the International Physical Activity Questionnaire. Main findings: The results of the present study showed that the physical education students were characterized by a higher level of physical activity in each discussed type of physical activity than their peers studying sports. The study also revealed that the women showed greater physical activity than the men. It was only in vigorous-intensity physical activity that the men obtained higher results than the women. Conclusions: The male first-year students of the University of Physical Education in Warsaw prefer vigorous-intensity physical activity, and the female students prefer both moderate-intensity activities and walking. With the development of sports infrastructure and the growing number of sports services, women have become more physically active and achieve results rivaling, or at times, surpassing the results obtained by men.


2002 ◽  
Vol 27 (5) ◽  
pp. 449-462 ◽  
Author(s):  
Michelle D. Fortier ◽  
Peter T. Katzmarzyk ◽  
Claude Bouchard

Associations among baseline physical activity, aerobic fitness, changes in physical activity, and 7-y changes in adiposity were determined. The sample consisted of 602 males and 644 females, aged 20-69 y, from the 1981 Canada Fitness Survey and the 1988 Campbell's Survey. Questionnaire-derived measures of physical activity level consisted of activity energy expenditure (AEE) and time spent on physical activity. Participants were grouped into physical activity level categories by AEE and physical activity intensity (based on MET values), and physical activity level changes were determined from movement between tertiles of AEE from baseline to follow-up. Aerobic fitness levels at baseline were determined using the Canadian Aerobic Fitness Test. Changes in body mass, the sum of five skinfolds (SF5), and waist circumference (WC) were used as indicators of adiposity change. ANCOVA and multiple regression analyses indicated that neither baseline physical activity levels, intensity, physical activity change categories, nor aerobic fitness levels were significant predictors of changes in adiposity. In conclusion, physical activity was not predictive of 7-y changes in indicators of adiposity in this sample. Key words: weight gain, longitudinal study, obesity, lifestyle


2021 ◽  
Author(s):  
Yoichi Toyoshima ◽  
Nobuyuki Yajima ◽  
Tetsuya Nemoto ◽  
Osamu Namiki ◽  
Katsunori Inagaki

Abstract Objective: This study evaluated the relationship between rheumatoid arthritis (RA) disease activity level and physical activity (PA) by using an accelerometer and self-reported questionnaire.Results: The cross-sectional study included 34 patients with RA. We classified patients with a Disease Activity Score 28-erythrocyte sedimentation rate (DAS28-ESR) of less than and higher than 3.2 into the low-disease-activity (LDA) group and moderate/high-disease-activity (MHDA) group, respectively. PA was assessed using a triaxial accelerometer. We measured the wear time, time of vigorous-intensity PA (VPA), moderate-intensity PA (MPA), light-intensity PA (LPA), and sedentary behavior per day by using this device. Moreover, we evaluated the relationship between accelerometer-measured and self-reported PAs in each group. The accelerometer-measured moderate-to-vigorous PA (MVPA) was 17.2 min/day and 10.6 min/day in the MHDA group and LDA group (p < .05), respectively. No significant association was observed between RA disease activity level and accelerometer-measured PA with adjustment for age and Functional Assessment of Chronic Illness Therapy-Fatigue score. No correlation was noted between accelerometer-measured MVPA and self-reported MVPA in the MHDA group, but these factors were correlated in the LDA group (rs = 0.5, p < .05). The RA disease activity level and accelerometer-measured PA were not correlated.


2020 ◽  
Vol 11 (5) ◽  
pp. 8-11
Author(s):  
Jitendra Sorout ◽  
Satyanath Reddy Kodidala ◽  
Harsha Soni ◽  
Priyanka Singh ◽  
Nirmal Sharma

Background: Newly admitted medical students experience a different curriculum, which can be a stressor and may be the reason of stress during student life. Stress may affect physiological, psychological and cognitive functions of the students. Aims and Objective: Aim of the study was to assess the effect of academic stress on physical activity level and cognitive functions in first year medical students. Materials and Methods: This observational study was conducted on 30 healthy newly admitted medical students (18 -25 years). The data was collected thrice, baseline, after two months and after four months. Stress was assessed by using DASS and Cohen perceived stress scale (PSS). GPAQ was used to estimate the physical activity level. And cognitive functions were assessed by using subjective method (MMSE questionnaire) and objective method (P300). Results: No significant difference of mean values of age, height, weight, BMI, physical activity level, DASS score, PSS and P300 latency were observed over the time to which recording was taken. The mean score of PAL represents the high physical activity. But the score of DASS and PSS represent severe and moderate stress level respectively. The significant difference was seen in the mean values of MMSE score and P300 amplitude over the time to which recording taken. Conclusion: The present study results we can conclude that students have stress during their academic period. And this stress might be helpful in potentiating the cognitive functions with the optimum physical activity.


Author(s):  
Charlotte Schouller ◽  
Jean Francis Maillefert ◽  
Jean Marie Casillas ◽  
Daniel Wendling ◽  
Frank Verhoeven

2020 ◽  
Author(s):  
Lyudmila Sizova

BACKGROUND The research interest is the study of the quality of life of patients with rheumatoid arthritis of different duration. OBJECTIVE The aim of study was to compare the quality of life in patients with early rheumatoid arthritis (RA) against patients with long-term RA. METHODS The study included 164 participants: 114 outpatients with early RA, and 50 outpatients with long-term RA. Assessment of life quality in patients with RA detected impaired parameters of the HAQ, SF-36, QOL-RA Scale already during the first year of the disease. RESULTS The HAQ test found a comparable frequency of severe functional disorders in patients with early and long-term RA. According to the SF-36 questionnaire, patients with early RA suffered from physical pain than patients with long-term RA. The QOL-RA Scale demonstrated that patients in the early stages of the disease, the lowest scores for the "arthritis" and "joint pain", and participants with long-term RA for "health" also. CONCLUSIONS Results indicated that these questionnaires may be used for scientific purposes to identify the most susceptible parameters of the quality of life and to provide benefits for monitoring health status and correct choice of drugs. CLINICALTRIAL The Scientific Council of the Orenburg State Medical Academy (currently the University) approved research in 2005 year (Protocol No. 5). All patients gave their written consent to participate in the scientific study.


PLoS ONE ◽  
2017 ◽  
Vol 12 (11) ◽  
pp. e0188102 ◽  
Author(s):  
Birgitte Sanda ◽  
Ingvild Vistad ◽  
Linda Reme Sagedal ◽  
Lene Annette Hagen Haakstad ◽  
Hilde Lohne-Seiler ◽  
...  

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