scholarly journals Worldwide emergence of multiple clades of enterovirus 68

2012 ◽  
Vol 93 (9) ◽  
pp. 1952-1958 ◽  
Author(s):  
Rafal Tokarz ◽  
Cadhla Firth ◽  
Shabir A. Madhi ◽  
Stephen R. C. Howie ◽  
Winfred Wu ◽  
...  
Keyword(s):  
Phylogenetic Analysis ◽  
North America ◽  
Respiratory Disease ◽  
Respiratory Illness ◽  
Genetic Differences ◽  
Human Enterovirus ◽  
The Past ◽  
The Usa

Human enterovirus 68 (EV-D68) is a historically rarely reported virus linked with respiratory disease. In the past 3 years, a large increase in respiratory disease associated with EV-D68 has been reported, with documented outbreaks in North America, Europe and Asia. In several outbreaks, genetic differences were identified among the circulating strains, indicating the presence of multiple clades. In this report, we analyse archived and novel EV-D68 strains from Africa and the USA, obtained from patients with respiratory illness. Phylogenetic analysis of all EV-D68 sequences indicates that, over the past two decades, multiple clades of the virus have emerged and spread rapidly worldwide. All clades appear to be currently circulating and contributing to respiratory disease.

BRD in 2014: where have we been, where are we now, and where do we want to go?

2014 ◽  
Vol 15 (2) ◽  
pp. 120-122 ◽  
Author(s):  
W. Mark Hilton
Keyword(s):  
North America ◽  
Respiratory Disease ◽  
Monitoring System ◽  
Health Monitoring ◽  
Animal Health ◽  
Feedlot Cattle ◽  
Health Concern ◽  
Health Monitoring System ◽  
The Us ◽  
The Usa

AbstractBovine respiratory disease (BRD) is a worldwide health concern and is the number one disease of stocker, backgrounder, and feedlot cattle in North America. In feedlots in the USA, BRD accounts for 70–80% of all feedlot morbidity and 40–50% of all mortality. In 2011, the US Department of Agriculture's National Animal Health Monitoring System conducted a feedlot study that showed 16.2% of all feedlot cattle were treated for BRD. It is universally accepted that this number is distressingly high and that our industry has the tools available to reduce the incidence of BRD.

Delimitation of European Crepidotus stenocystis as different from the North American species C. brunnescens (Inocybaceae, Agaricales)

Phytotaxa ◽  
2017 ◽  
Vol 328 (2) ◽  
pp. 127 ◽  
Author(s):  
SOŇA JANČOVIČOVÁ ◽  
SLAVOMÍR ADAMČÍK ◽  
BRIAN P. LOONEY ◽  
MIROSLAV CABOŇ ◽  
MÁRIA ČAPLOVIČOVÁ ◽  
...  
Keyword(s):  
Phylogenetic Analysis ◽  
North America ◽  
Distinct Species ◽  
Published Data ◽  
Similar Species ◽  
Spore Ornamentation ◽  
The North ◽  
The Usa ◽  
Lsu Nrdna ◽  
Original Type

Crepidotus stenocystis and C. brunnescens are morphologically similar species defined by globose to subglobose spores, the presence of clamp connections in all tissues and bottle-like or flask-like cheilocystidia. They are also similar in the pileal aspect which is hygrophanous, glabrous or white-fibrillose, at first white but becoming brownish with age. Each are described from separate continents and have only been reported from their respective continents, C. stenocystis from Europe and C. brunnescens from North America. The phylogenetic analysis of ITS and LSU nrDNA regions from original type material confirms the existence of two distinct species, C. brunnescens that is more closely related to C. malachioides, and C. stenocystis that is more closely related to C. applanatus. Crepidotus stenocystis differs from C. brunnescens by its more prominent spore ornamentation and longer cheilocystidia that are frequently narrowly utriform. Based on the studied material and published data, it seems that C. stenocystis is distributed throughout all of Europe and does not occur in North America, whereas C. brunnescens is only known from Michigan in the USA.

scholarly journals Current Scenario of Covid-19 with Epidemiological and Phylogenetic Analysis of Pakistani Coronavirus: A Review

2020 ◽  
Vol 7 (3) ◽  
pp. 45-65
Author(s):  
Asma Altaf ◽  
Wafa Iqbal ◽  
Sidra Younis ◽  
Farah Deebah
Keyword(s):  
Phylogenetic Analysis ◽  
Respiratory Disease ◽  
Recovery Rate ◽  
Current Knowledge ◽  
Respiratory Illness ◽  
Epidemiological Analysis ◽  
Corona Virus ◽  
Current Scenario ◽  
Virus Strains ◽  
Review Current

A novel corona virus named as 2019 n-CoV was identified to be the actual cause of an outbreak of respiratory illness in Wuhan, China beginning in late December 2019. This respiratory disease was named as COVID-19 by WHO. There are many countries affected by COVID-19 including Pakistan. In this review we have provided a brief introduction of COVID-19 and discussed epidemiological and phylogenetic analysis of Pakistani novel corona virus strain. Our epidemiological analysis of data till 16th May 2020 showed rapidly increasing number of new cases, while at the same time a higher recovery rate than number of deaths in Pakistan. Moreover, phylogenetic analysis indicated that 2019-nCoV strain of Pakistan shared 100 % bootstrap value with various countries’ novel corona virus strains. Similarly, phylogenetic analysis was also conducted in comparison with SARS species to confirm our results. In this review, current knowledge of pathogenesis, diagnosis, treatment of COVID-19 and comorbidities which could be helpful in offering novel understanding and possible therapeutic targets for fighting against the COVID-19 infection are discussed.

scholarly journals Genomic analysis of two novel human enterovirus C genotypes found in respiratory samples from Peru

2013 ◽  
Vol 94 (1) ◽  
pp. 120-127 ◽  
Author(s):  
Rafal Tokarz ◽  
David L. Hirschberg ◽  
Stephen Sameroff ◽  
Saddef Haq ◽  
Giannina Luna ◽  
...  
Keyword(s):  
Phylogenetic Analysis ◽  
Respiratory Disease ◽  
Hypervariable Region ◽  
Genomic Analysis ◽  
Genomic Rearrangement ◽  
Human Enterovirus ◽  
Structural Genes ◽  
Vp1 Protein

We report the discovery of two enteroviruses detected in nasopharyngeal samples obtained from subjects with respiratory disease in Peru. Phylogenetic analysis indicated that both viruses belong to a clade within the species Human enterovirus C, which includes the recently characterized human enteroviruses 109 and 104. Members of this clade have undergone significant genomic rearrangement, as indicated by deletions in the hypervariable region of the 5′ UTR and the VP1 protein, as well as recombination within the non-structural genes. Our findings and review of published sequences suggests that several novel human enterovirus C serotypes are currently circulating worldwide.

Cross-culture outcomes of a brazilian professor Fulbright in the USA

2017 ◽  
Vol 26 (50) ◽  
pp. 115
Author(s):  
Marcelo Da Silva Leite ◽  
Celeste Gaia
Keyword(s):  
Higher Education ◽  
Low Cost ◽  
Cross Culture ◽  
College And University ◽  
Governmental Agencies ◽  
The Past ◽  
University Curriculum ◽  
Fulbright Scholar ◽  
The Usa ◽  
Higher Education Costs

Over the past decade due the expansion of globalization there has been an increasing emphasis on internationalization among faculty, administration and accrediting agencies in the Higher Education.  Although to promote internationalization in the Higher Education, costs are a big challenge, one way to have the international actions with low cost, it is seeking for grants from different governmental agencies and foundations.The Fulbright Scholar program provides a long-standing and externally-funded means for internationalizing college and university curriculum. This article is going to share the perspective   of a Brazilian Fulbright Scholar at an American college and the institution perspective of the Fulbright scholar participation at the College.

scholarly journals Triangulating abuse liability assessment for flavoured cigar products using physiological, behavioural economic and subjective assessments: a within-subjects clinical laboratory protocol

BMJ Open ◽  
2018 ◽  
Vol 8 (10) ◽  
pp. e023850
Author(s):  
Catherine S Wall ◽  
Rose S Bono ◽  
Rebecca C Lester ◽  
Cosima Hoetger ◽  
Thokozeni Lipato ◽  
...  
Keyword(s):  
Clinical Laboratory ◽  
Subjective Effects ◽  
Latin Square ◽  
Abuse Liability ◽  
Smoke Inhalation ◽  
Nicotine Concentration ◽  
The Past ◽  
The Usa ◽  
Behavioural Economic ◽  
Scientific Meetings

IntroductionIn the USA, Food and Drug Administration regulations prohibit the sale of flavoured cigarettes, with menthol being the exception. However, the manufacture, advertisement and sale of flavoured cigar products are permitted. Such flavourings influence positive perceptions of tobacco products and are linked to increased use. Flavourings may mask the taste of tobacco and enhance smoke inhalation, influencing toxicant exposure and abuse liability among novice tobacco users. Using clinical laboratory methods, this study investigates how flavour availability affects measures of abuse liability in young adult cigarette smokers. The specific aims are to evaluate the effect of cigar flavours on nicotine exposure, and behavioural and subjective measures of abuse liability.Methods and analysesParticipants (projected n=25) are healthy smokers of five or more cigarettes per day over the past 3 months, 18–25 years old, naive to cigar use (lifetime use of 50 or fewer cigar products and no more than 10 cigars smoked in the past 30 days) and without a desire to quit cigarette smoking in the next 30 days. Participants complete five laboratory sessions in a Latin square design with either their own brand cigarette or a session-specific Black & Mild cigar differing in flavour (apple, cream, original and wine). Participants are single-blinded to cigar flavours. Each session consists of two 10-puff smoking bouts (30 s interpuff interval) separated by 1 hour. Primary outcomes include saliva nicotine concentration, behavioural economic task performance and response to various questionnaire items assessing subjective effects predictive of abuse liability. Differences in outcomes across own brand cigarette and flavoured cigar conditions will be tested using linear mixed models.Ethics and disseminationThe Virginia Commonwealth University Institutional Review Board approved the study (VCU IRB: HM20007848). Dissemination channels for study findings include scientific journals, scientific meetings, and policy briefs.Trial registration numberNCT02937051.

Economics of respiratory disease in dairy replacement heifers

2020 ◽  
Vol 21 (2) ◽  
pp. 143-148
Author(s):  
Michael W. Overton
Keyword(s):  
Respiratory Disease ◽  
Milk Production ◽  
Incident Case ◽  
Data Set ◽  
Dairy Heifers ◽  
The Usa ◽  
History Of ◽  
On Farm ◽  
The Impact ◽  
Selective Culling

AbstractBovine respiratory disease (BRD) is a frequent disease concern in dairy cattle and is most commonly diagnosed in young dairy heifers. The impact of BRD is highly variable, depending on the accuracy and completeness of detection, effectiveness of treatment, and on-farm culling practices. Consequences include decreased rate of weight gain, a higher culling risk either as heifers or as cows, delayed age at first service, delayed age at first calving, and in some cases, lower future milk production. In this data set of 104,100 dairy replacement heifers from across the USA, 36.6% had one or more cases diagnosed within the first 120 days of age with the highest risk of new cases occurring prior to weaning. Comparison of the raising cost for heifers with BRD and those without a recorded history of BRD resulted in an estimated cost per incident case occurring in the first 120 days of age of $252 or $282, depending upon whether anticipated future milk production differences were considered or not. Current market conditions contributed to a cost estimate that is significantly higher than previously published estimates, driven in part by the losses associated with selective culling of a subset of heifers that experienced BRD.

scholarly journals Bioinsecticides based on plant essential oils: a short overview

2020 ◽  
Vol 75 (7-8) ◽  
pp. 179-182
Author(s):  
Murray B. Isman
Keyword(s):  
Essential Oils ◽  
Crop Protection ◽  
Large Body ◽  
Regulatory Agencies ◽  
The European Union ◽  
Plant Essential Oils ◽  
The Past ◽  
Wide Range ◽  
The Usa ◽  
Regulatory Challenges

AbstractInterest in the discovery and development of plant essential oils for use as bioinsecticides has grown enormously in the past 20 years. However, successful commercialization and utilization of crop protection products based on essential oils has thus far lagged far behind their promise based on this large body of research, most notably because with the exceptions of the USA and Australia, such products receive no special status from regulatory agencies that approve new pesticides for use. Essential oil-based insecticides have now been used in the USA for well over a decade, and more recently have seen use in the European Union (EU), Korea, and about a dozen other countries, with demonstrated efficacy against a wide range of pests and in numerous crop systems. For the most part these products are based on commodity essential oils developed as flavor and fragrance agents for the food and cosmetic industries, as there are formidable logistic, economic, and regulatory challenges to the use of many other essential oils that otherwise possess potentially useful bioactivity against pests. In spite of these limitations, the overall prospects for biopesticides, including those based on essential oils, are encouraging as the demand for sustainably-produced and/or organic food continues to increase worldwide.

scholarly journals Remnant and the New Dark Age

Religions ◽  
2021 ◽  
Vol 12 (6) ◽  
pp. 372
Author(s):  
Edward Rommen
Keyword(s):  
North America ◽  
Moral Discourse ◽  
The Past ◽  
Personal Opinion

A new dark age has come upon us; as a result, Christianity and its churches in North America are no longer growing. One reason for this might be the widespread impression that Christians are hypocrites, saying they believe one thing while doing the opposite. However, that accusation would only be true if these believers actually believed the principles they are supposed to be violating. It is more likely that many Christians have, like those around them, abandoned truth in favor of personal opinion bringing moral discourse to a near standstill and intensifying the darkness by extinguishing the light of truth. Still, there is hope. In the past, it often was a faithful few, a remnant, who preserved the knowledge of that light and facilitated a new dawn. History shows us that the very movements that are today abdicating responsibility were once spiritual survivors themselves. They withdrew, coalesced around the remaining spark of truth in order to remember, preserve, and reignite. The thoughts and practices of these pioneers could guide the escape from today’s darkness.

scholarly journals Genomic Analysis of Avian Infectious Bronchitis Viruses Recently Isolated in South Korea Reveals Multiple Introductions of GI-19 Lineage (QX Genotype)

Viruses ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 1045
Author(s):  
Hyuk-Chae Lee ◽  
Sol Jeong ◽  
Andrew Y. Cho ◽  
Kyu-Jik Kim ◽  
Jun-Young Kim ◽  
...  
Keyword(s):  
Phylogenetic Analysis ◽  
South Korea ◽  
Infectious Bronchitis Virus ◽  
Economic Burden ◽  
Genomic Analysis ◽  
Multiple Introductions ◽  
Infectious Bronchitis ◽  
South Korean ◽  
Phylogeographic Analysis ◽  
The Past

Infectious bronchitis virus (IBV) was first identified in the 1930s and it imposes a major economic burden on the poultry industry. In particular, GI-19 lineage has spread globally and has evolved constantly since it was first detected in China. In this study, we analyzed S1 gene sequences from 60 IBVs isolated in South Korea. Two IBV lineages, GI-15 and GI-19, were identified in South Korea. Phylogenetic analysis suggested that there were six distinct subgroups (KM91-like, K40/09-like, and QX-like I to IV) of the South Korean GI-19 IBVs. Among them, QX-type III and IV subgroups, which are phylogenetically different from those reported in South Korea in the past, accounted for more than half of the total. Moreover, the phylogeographic analysis of the QX-like subgroups indicated at least four distinct introductions of GI-19 IBVs into South Korea during 2001–2020. The efficacy of commercialized vaccines against the recently introduced QX-like subgroups should be verified, and continuous international surveillance efforts and quarantine procedures should be enhanced to prevent the incursion of viruses.

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