scholarly journals A pilot study of assisting IVF by personalized Endo-Gym® exercises

2020 ◽  
Author(s):  
Katalin Csehek ◽  
Peter Tompa
Keyword(s):  
Assisted Reproductive Technologies ◽  
Polycystic Ovary ◽  
Reproductive Technologies ◽  
Pelvic Organ ◽  
Human Reproduction ◽  
Psychological Burden ◽  
Hormone Balance ◽  
Personal Coaching ◽  
General Wellbeing

SummaryAssisted reproductive technologies (ARTs), especially in vitro fertilization (IVF) have revolutionized human reproduction technology, helping millions of subfertile couples to conceive and deliver a baby. IVF, however, is not an easy procedure, as treatment cycles incur heavy financial, physical and psychological burden, yet they result in live birth less than once in four attempts. Based on our experience with 251 women, many in their 40s, here we suggest that Endo-Gym® method (for endocrine gymnastics), a combination of personalized physical exercises, fertility-optimizing diet and personal coaching, can significantly increase IVF success, probably by both reducing distress caused by repeated cycles and alleviating fertility-affecting problems, such as polycystic ovary syndrome (PCOS) and premature ovarian failure (POF). The program can also relieve other gynecological conditions, such as irregular or painful period, pelvic organ prolapse (POP) and incontinence, and is also often chosen by women as their regular fitness regime for general wellbeing. We provide detailed statistics of success in various conditions and suggest that distinct elements of Endo-Gym® cooperate to exert positive physiological and psychological effects that help re-establish sexual hormone balance and boost reproductive fitness. We anticipate that further, controlled testing will enable to put the benefits of Endo-Gym® on a rational basis and enable to introduce this approach as a beneficial complement of IVF, and maybe also other branches of ART.

IVF efficiency in different phenotypes of polycystic ovary syndrome

2021 ◽  
Vol 70 (4) ◽  
pp. 81-90
Author(s):  
Igor P. Nikolayenkov ◽  
Olga E. Kazymova ◽  
Dmitry S. Sudakov ◽  
Yulia R. Dymarskaya
Keyword(s):  
In Vitro Fertilization ◽  
Polycystic Ovary Syndrome ◽  
Metabolic Disorders ◽  
Assisted Reproductive Technologies ◽  
Polycystic Ovary ◽  
Reproductive Technologies ◽  
Ovary Syndrome ◽  
Vitro Fertilization ◽  
Hormonal Profile

Polycystic ovary syndrome occupies a leading place in the structure of endocrine infertility. This article presents the endocrine and metabolic features of the polycystic ovary syndrome phenotypes, as well as modern concepts of efficiency and complications of the use of assisted reproductive technologies, depending on the specific phenotype. The issues of polycystic ovary syndrome influence on selecting the method of assisted reproductive technologies, as well as possible complications that occur during in vitro fertilization and the features of the pregnancy course remain unresolved. The individualization of the approach seems to be promising when taking into account the differences in the hormonal profile and the features of metabolic disorders in each polycystic ovary syndrome phenotype. That may allow us to take one more step towards improving the effectiveness of in vitro fertilization and reducing the frequency of complications in patients with polycystic ovary syndrome.

scholarly journals Live birth after in vitro maturation versus standard in vitro fertilisation for women with polycystic ovary syndrome: protocol for a non-inferiority randomised clinical trial

BMJ Open ◽  
2020 ◽  
Vol 10 (4) ◽  
pp. e035334
Author(s):  
Xiaoying Zheng ◽  
Wei Guo ◽  
Lin Zeng ◽  
Danni Zheng ◽  
Shuo Yang ◽  
...  
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Live Birth ◽  
In Vitro Maturation ◽  
Assisted Reproductive Technologies ◽  
Polycystic Ovary ◽  
Reproductive Technologies ◽  
In Vitro Fertilisation ◽  
Ovary Syndrome ◽  
Infertile Women

IntroductionPolycystic ovary syndrome (PCOS) is the first common cause of anovulatory infertility. Currently, in vitro fertilisation (IVF) is recommended when conventional attempts have failed. In vitro maturation (IVM) of human oocytes is an emerging treatment option in infertile women with PCOS. It is a patient-friendly intervention, avoiding the risk of ovarian hyperstimulation syndrome, which is a serious complication of controlled ovarian stimulation in the standard IVF procedure. We plan a randomised controlled trial (RCT) to evaluate whether IVM is non-inferior to the standard IVF for live birth in women with PCOS.Methods and analysisThis is a single-centre, open-label, non-inferiority RCT performed in a large reproductive medicine centre in China. Infertile women with PCOS will be randomised to receive either IVM or standard IVF in a 1:1 treatment ratio after informed consent. IVF procedures used in our study are all standard treatments and other standard-assisted reproductive technologies will be similar between the two groups. The primary outcome is ongoing pregnancy leading to live birth within 6 months of the first oocyte retrieval cycle after randomisation. Pregnancy outcome, maternal safety and obstetric and perinatal complications will be secondary outcomes. The planned sample size is 350 (175 per group).Ethics and disseminationEthical permission was acquired from the Ethics Committee of Peking University Third Hospital. The results will be issued to publications through scientific journals and conference reports.Trial registration numberNCT03463772.

scholarly journals Pregnancy and live birth rates in women with endometriosis related infertility in Latvia

2019 ◽  
Vol 8 (3) ◽  
pp. 808
Author(s):  
Jekaterina Avdotina ◽  
Aleksandra Mezecka-Oleinika ◽  
Vija Silina ◽  
Zane Vitina
Keyword(s):  
Laparoscopic Surgery ◽  
Live Birth ◽  
Assisted Reproductive Technologies ◽  
Reproductive Technologies ◽  
Human Reproduction ◽  
Optimal Time ◽  
First Year ◽  
Vitro Fertilization ◽  
Significant Difference

Background: Women with endometriosis experience painful symptoms and/or infertility, others have no symptoms at all. According to European Society of Human Reproduction and Embryology guidelines, surgery and assisted reproductive technologies (ART) are an appropriate treatment in cases of endometriosis-associated infertility. There are controversial data on the results of surgery and ART in patients with endometriosis.Methods: Retrospective analysis including 99 infertile patients aged between 25 and 48 years old. All of them had laparoscopic surgery as the primary option. 51 of them undergoing in vitro fertilization or intracytoplasmic sperm injection or frozen embryo transfer from 2003 through 2018 at SIA ‘Clinic EGV’.Results: The mean age of women was 34.2±4.5. In 56 (33.5%) cases was only surgery with 28 (50.9%) biochemical pregnancies and 26 (48.1%) live birth. In 111 (66.5%) cases there were surgery with ART with 48 (47.6%) biochemical pregnancies and 23 (22.7%) live birth. In 1 group patients mean age 30.7±4.6 and 2 group with mean age 35.1±4.2 (p=0.000). It was found that there is significant difference between endometriosis phenotype, infertility type, duration of infertility, repeated laparoscopic surgery, ART cycles, retrieved oocyte count and biochemical pregnancy rate.Conclusions: Patients with endometriosis related infertility should undergo surgical treatment as the primary option. Those patients who do not become pregnant after surgery must be treated with assisted reproductive technology. The optimal time to perform ART is first year after endometriosis surgery.

Assisted Reproductive Technologies and the Pregnancy Process: Developing an Equality Model to Protect Reproductive Liberties

1999 ◽  
Vol 25 (4) ◽  
pp. 455-477
Author(s):  
Judith F. Daar
Keyword(s):  
Assisted Reproductive Technologies ◽  
Reproductive Technologies ◽  
Human Reproduction ◽  
Parental Status ◽  
Quarter Century ◽  
Vitro Fertilization ◽  
First Child ◽  
Frozen Embryos ◽  
The World

The world of assisted reproductive technologies (ART) has forced our society to confront scenarios that were unimaginable a mere quarter century ago. The birth of Louise Brown in 1978, the first child conceived through in vitro fertilization (IVF), introduced to the world the notion of asexual reproduction. The bitter battle over the parental status of Baby M., a baby born by a surrogate mother in the early 1980s, engendered a public debate over the interaction between contract law, family law and reproductive liberties that still rages today. In 1992, the highly publicized divorce of Junior and Mary Sue Davis focused national attention on the issue of proper disposition of frozen embryos. This case highlighted the fact that conception and pregnancy could be separated by a significant amount of time as a result of cryopreservation. While each of these events marked a step forward in the march toward total technological mastery of human reproduction, they also suggest that future struggles involving ART will grow increasingly fierce and complicated as our fund of knowledge increased. This Article suggests that current disputes over the disposition of frozen embryos are emblematic of that struggle.

scholarly journals Assisted Reproductive Technologies as Veritable Tools for Improving Production Efficiencies of N’dama and Muturu Cattle Breeds in Nigeria-A Review

2021 ◽  
Author(s):  
Cornelius Nwoga ◽  
Nnanna Ikeh ◽  
Matthew Onodugo ◽  
Paul Baiyeri ◽  
Ndubuisi Machebe
Keyword(s):  
Artificial Insemination ◽  
Assisted Reproductive Technologies ◽  
Developed Countries ◽  
Reproductive Technologies ◽  
Human Reproduction ◽  
Vitro Fertilization ◽  
Beef Cow ◽  
Cattle Breeds ◽  
Multiple Ovulation

Assisted reproductive technologies (ART) that have come to stay and are still being improved upon in developed countries are still in their infancy stage in developing countries like Nigeria. Nigeria’s cattle population is estimated to be around 18.4 million. The number is far insufficient to meet the country’s demand for meat, milk, and other cow products, let alone contribute to GDP. N’dama and Muturu are both Nigerian breeds that are resistant to trypanosomosis. They are humpless longhorn and humpless shorthorn types of beef cattle. The dairy and beef cow industries’ inadequate adoption of ART is partly to blame for Nigeria’s low cattle output. Sex determination, multiple-ovulation and embryo transfer (MOET), oestrus synchronization, artificial insemination (AI), in vitro fertilization (IVF), cloning, and genetic engineering are all examples of assisted reproductive technologies. It has been reported in humans, rodents and domestic animals, abnormal fetuses, newborns and adult offspring arise from ART. Improper matching of breeding animals mostly leads to overfat calves. This review centers on the applications and potentials of ART in the production of trypanotolerant N’dama and Muturu cattle breeds. Some unorthodox medicines which have proven effective in human reproduction can circumvent the shortfalls in the adoption of ART.

Reproductive Technologies

Anthropology ◽  
2019 ◽  
Author(s):  
Amy Speier ◽  
Caridad Zamarripa
Keyword(s):  
Assisted Reproductive Technologies ◽  
Intrauterine Insemination ◽  
Petri Dish ◽  
Reproductive Technologies ◽  
Human Reproduction ◽  
Vitro Fertilization ◽  
Gay Fathers ◽  
The People ◽  
Future Child

Reproductive technologies are those technologies that aid in animal and human reproduction. Assisted reproductive technologies (ARTs) are more narrowly defined as those technologies that help people suffering from social or bodily infertility create a family. Socially infertile includes single women and men as well as homosexual couples who rely on donated gametes for the creation of a future child. Intrauterine Insemination (IUI) is usually the first step taken by couples having trouble conceiving. The most general type of reproduction technology is in vitro fertilization (IVF), which means that the egg is retrieved from a woman’s uterus and sperm is introduced to these eggs in a petri dish. In the case of male infertility, intracytoplasmic sperm injections (ICSI) may be employed, which means that sperm are injected directly into the egg. IVF may include the use of donated sperm, oocytes, and embryos. In addition to gamete donation, surrogacy may be employed in cases where an intended mother or intended gay fathers cannot carry a pregnancy to term. In addition to being used to create families, contraception is also considered a reproductive technology. Anthropologists have been conducting ethnographic analyses of reproductive technologies by studying the people intimately engaged with these varying technologies. Scholarship revolves around major questions about markets and gift exchange, kinship, and how our understandings of family have shifted with the advent of reproductive technologies, as well as globalization and the ways in which bodies, people, and technologies traverse the globe.

scholarly journals The Impact of Third Party Reproduction on Family and Kinship

2020 ◽  
Author(s):  
Zohreh Behjati Ardakani ◽  
Mehrdad Navabakhsh ◽  
Soraya Tremayne ◽  
Mohammad Mehdi Akhondi ◽  
Fahimeh Ranjbar ◽  
...  
Keyword(s):  
Ethical Issues ◽  
Assisted Reproductive Technologies ◽  
Human Life ◽  
Reproductive Technologies ◽  
Unintended Consequences ◽  
Third Party ◽  
Human Reproduction ◽  
The Family ◽  
The Impact

The development of in vitro fertilization (IVF) in the UK, in 1978, proved a major breakthrough in the process of human reproduction, which had remained constant in human history. The impact of IVF and the ensuing assisted reproductive technologies (ARTs) has not been limited in revolutionizing the "natural" practice of biological reproduction, but has reached out to and affected almost every institution in society. Family and kinship, as the social expression of reproduction and the institutions which are the most transparently structured realm of human life are those most profoundly affected by ARTs. Although literature on the implications of ARTs is in general abundant, this article presents new insights on their impact on family and kinship in Iran, which remains a unique case in the Muslim world. It explores the particular way ARTs, especially third-party donation, have been endorsed and practiced in Iran, and their consequences for the family, the infertile individuals, and their position vis-à-vis their kin and social group. The conclusion points to the lack of clarity concerning the initial rulings by the Islamic jurists, who allowed the practice of ARTs, and which has led to a number of unintended consequences regarding the legal, religious, cultural, and ethical issues, affecting the family, its structure and the relationship between the kin group. These consequences range, inter alia, from the question of the anonymity of third-party donor, to the permissibility of gamete donation between blood relatives, and to the absence of enforceable legislation.

scholarly journals Ethical and legal dilemmas in infertility treatment

2004 ◽  
pp. 85-91 ◽  
Author(s):  
Svetlana Dragojevic-Dikic ◽  
Saveta Draganic ◽  
Srdjan Dikic ◽  
Vladimir Pilija
Keyword(s):  
Assisted Reproductive Technologies ◽  
Reproductive Technologies ◽  
Infertility Treatment ◽  
Human Reproduction ◽  
Ethical Aspects ◽  
Vitro Fertilization ◽  
Reproductive Techniques ◽  
Embryo Stage ◽  
Assisted Fertilization

One of the main characteristics of the new millennium is the affirmation of human rights in all aspects of human existence, with the intention of turning declarative statements into reality. Development of up-to-date assisted reproductive technologies (ART) and their application in infertility treatment have raised numerous ethical, legal, religious, social and other questions. In vitro fertilization, donation of gametes, embryos and pre-embryos, cryopreservation of gametes, embryos, ovarian and testicular tissues, embryo transfer, genetic reproductive techniques, cloning and other sophisticated methods used in infertility treatment require cooperation between the medical and legal professions. Ethical aspects of human reproduction and assisted fertilization are based on full respect of the life of an individual even before conception, from pre-embryo stage, via embryo stage and fetus stage to a newborn infant. Regarding investigative and clinical projects, this standpoint implies the legalization of all ART procedures, unencumbered exchange of information and consensus about their application, and adherence to the basic ethical principles of autonomy benefit, justice and common welfare. Ethical postulates provide unequivocal directions in the creation of new life and resolve all possible ethical dilemmas, protecting the rights of doctors and participant in relevant procedures alike and reasserting the crucial principle - respect of human dignity.

The role of the growth hormone in assisted reproductive technologies cycles

GYNECOLOGY ◽  
2019 ◽  
Vol 21 (4) ◽  
pp. 6-8
Author(s):  
Andrey Y Romanov ◽  
Anastasiya G Syrkasheva ◽  
Nataliya V Dolgushina ◽  
Elena A Kalinina
Keyword(s):  
Growth Hormone ◽  
Live Birth ◽  
Ovarian Stimulation ◽  
Assisted Reproductive Technologies ◽  
Polycystic Ovary ◽  
Live Birth Rate ◽  
Reproductive Technologies ◽  
Blood Levels ◽  
Main Research ◽  
Poor Ovarian Responders

The paper analyzes the literature data on the use of the growth hormone (GH) in ovarian stimulation in assisted reproductive technologies (ART). Routine use of GH in ovarian stimulation in patients with a normal GH level does not increase pregnancy and childbirth rates in ART. Also, no benefits of using GH have been identified for patients with polycystic ovary syndrome, despite the increase in insulin and IGF-1 blood levels. The main research focus is to study the use of GH in patients with poor ovarian response. According to the meta-analysis conducted by X.-L. Li et al. (2017), GH in ovarian stimulation of poor ovarian responders increases the number of received oocytes, mature oocytes number, reduces the embryo transfer cancellation rate and does not affect the fertilization rate. The pregnancy and live birth rates are significantly higher in the group of GH use - by 1.65 (95% CI 1.23-2.22) and 1.73 (95% CI 1.25-2.40) times, respectively. Thus, it is advisable to use GH in ovarian stimulation in poor ovarian responders, since it allows to increases live birth rate in ART. However, further studies should determine the optimal GH dose and assesse it`s safety in ART programs.

Thickness of endometrium: predictor of the effectiveness of IVF/ICSI programs (literature review)

GYNECOLOGY ◽  
2018 ◽  
Vol 20 (1) ◽  
pp. 113-116
Author(s):  
L A Bagdasaryan ◽  
I E Korneyeva
Keyword(s):  
Assisted Reproductive Technologies ◽  
Endometrial Thickness ◽  
Molecular Genetic ◽  
Uterine Cavity ◽  
Reproductive Technologies ◽  
Genetic Characteristics ◽  
Vitro Fertilization ◽  
Need To Evaluate ◽  
The Relationship

The aim of the study is to systematically analyze the data available in the modern literature on the relationship between endometrial thickness and the frequency of pregnancy in the program of assisted reproductive technologies (ART). Materials and methods. The review includes data from foreign and domestic articles found in PubMed on this topic. Results. The article presents data on the relationship between the thickness of the endometrium and the frequency of pregnancy in ART programs. The greatest number of studies is devoted to the evaluation of the relationship between the thickness of the endometrium and the frequency of pregnancy on the day of the ovulation trigger. Data are presented on the existence of a correlation between the thickness of the endometrium measured on the day of the ovulation trigger and the frequency of clinical pregnancy, as well as data on the need to evaluate the structure of the endometrium and the state of subendometric blood flow. The importance of multilayered (three-layered) endometrium as a prognostic marker of success in in vitro fertilization/intracytoplasmic sperm injection programs in the ovum is emphasized. The conclusion. The thickness of the endometrium can not be used as an argument for canceling the cycle or abolishing embryo transfer to the uterine cavity. Further studies in this direction are needed with a study of the morphological and molecular genetic characteristics of the endometrium, which in the future will allow us to evaluate the relationship between the thickness of the endometrium and the probability of pregnancy.

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