scholarly journals Effectiveness of Localized Lockdowns in the SARS-CoV-2 Pandemic

2020 ◽  
Author(s):  
Yige Li ◽  
Eduardo A Undurraga ◽  
Jose Ramon Zubizarreta
Keyword(s):  
Health Policy ◽  
Severe Acute Respiratory Syndrome ◽  
Mathematical Models ◽  
Empirical Evidence ◽  
Spillover Effects ◽  
Policy Option ◽  
Causal Effects ◽  
Economic Costs ◽  
The World ◽  
Pharmaceutical Interventions

Six months into the pandemic, non-pharmaceutical interventions (e.g., social distancing, lockdowns) are the only available measure to control severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) transmission. Around the world, policymakers have implemented localized lockdowns in small geographic areas to prevent the spread of the disease. As governments ease restrictions, localized lockdowns are becoming a relevant policy option in cases of resurgence, as they can, in principle, reduce social and economic costs compared to larger-scale SARS-CoV-2 suppression strategies. The effects of non-pharmaceutical interventions have been typically described using mathematical models; however, there is a lack of empirical evidence of their causal effects to inform health policy. Using an integrated dataset from Chile, we estimated the direct and indirect (spillover) causal effects of localized lockdowns on SARS-CoV-2 transmission. Our results show that the effectiveness of localized lockdowns is strongly modulated by duration and is affected by spillover effects from neighboring geographic areas. Our projections suggest that extending localized lockdowns will slow down the epidemic. However, by themselves, localized lockdowns will be unable to control epidemic growth due to spillovers from neighboring areas with high interdependencies, unless those contiguous areas also implement lockdowns.

scholarly journals The Common Interests of Health Protection and the Economy: Evidence from Scenario Calculations of COVID-19 Containment Policies

2020 ◽  
Author(s):  
Florian Dorn ◽  
Sahamoddin Khailaie ◽  
Marc Stoeckli ◽  
Sebastian C Binder ◽  
Berit Lange ◽  
...  
Keyword(s):  
Public Health ◽  
Empirical Evidence ◽  
Health Protection ◽  
Common Interest ◽  
Economic Costs ◽  
Exit Strategy ◽  
Common Interests ◽  
The Common ◽  
Pharmaceutical Interventions ◽  
Opening Process

Several countries use shutdown strategies to contain the spread of the COVID-19 epidemic, at the expense of massive economic costs. While this suggests a conflict between health protection and economic objectives, we examine whether the economically optimal exit strategy can be reconciled with the containment of the epidemic. We use a novel combination of epidemiological and economic simulations for scenario calculations based on empirical evidence from Germany. Our findings suggest that a prudent opening is economically optimal, whereas costs are higher for a more extensive opening process. This rejects the view that there is a conflict with health protection. Instead, it is in the common interest of public health and the economy to relax non-pharmaceutical interventions in a manner that keeps the epidemic under control.

Non-Pharmaceutical Interventions are measures to control coronavirus disease-2019 (COVID-19) transmission in India

Coronaviruses ◽  
2020 ◽  
Vol 01 ◽  
Author(s):  
Ponnuswamy Vijayaraghavan ◽  
Srikrishnan Rajendran Sriramkumar
Keyword(s):  
United States ◽  
Great Britain ◽  
Severe Acute Respiratory Syndrome ◽  
Age Groups ◽  
Viral Disease ◽  
Control Measures ◽  
Whole Genome ◽  
The World ◽  
Chennai City ◽  
Pharmaceutical Interventions

: The coronavirus disease 19 (COVID-19) is a pathogenic and transmittable viral disease cause by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and this disease was emerged on December 2019 in Wuhan, China. It was later spread across the world, including United States, Great Britain, Brazil, Russia, Germany, Spain, Italy, Iran, Pakistan, India and other countries. The whole genome of SARS-CoV-2 shared some similarity with SARS virus, hence bat was suspected to spread this virus in China. However human to human transfer was reported. In India, more than 300 COVID-19 cases were reported on March 21, 2020 and these numbers were increased as 892551 on July 13, 2020. These numbers of COVID-19 cases were detected from a total of 11806256 samples according to the report given by Government of India. As on July 13, Maharashtra state of India recorded a total of 254427 cases and 10289 deaths were registered. Tamilnadu was another state screened more number of COVID-19 cases, followed by Maharashtra. As on July 6, 114978 COVID-19 cases were reported in Tamilnadu and 1571 deaths were recorded. In Tamilnadu alone, over 3000 COVID-19 cases were reported daily from July first week to second week and total cases were 142798 on July 13, 2020. Among these cases, 78573 COVID-19 cases were detected in Chennai city alone accounted about 62% of total COVID-19 cases. It was earlier believed that patients over aged 60 and less than 10 were highly vulnerable to this disease. However, this disease affected all age groups. To prevent COVID-19, no approved antiviral vaccine or drug has yet been discovered. COVID-19 is transmitted through droplets during coughing and sneezing by symptomatic and asymptomatic carriers. Non-pharmaceutical interventions such as washing hands and social distancing are effective measures to control COVID-19 transmission in India. The present study was designed to analyze the control measures of COVID-19 infection and ground reality to control COVID-19 outbreak.

The relevance of dietetic approach of Ayurveda from the perspective of COVID-19 pandemic

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 748-752
Author(s):  
Swapnali Khabade ◽  
Bharat Rathi ◽  
Renu Rathi
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Healthy Person ◽  
World Health ◽  
Physical And Mental Health ◽  
Leading Role ◽  
Global Pandemic ◽  
The People ◽  
The World ◽  
Health Organization ◽  
The Individual

A novel, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causes severe acute respiratory syndrome and spread globally from Wuhan, China. In March 2020 the World Health Organization declared the SARS-Cov-2 virus as a COVID- 19, a global pandemic. This pandemic happened to be followed by some restrictions, and specially lockdown playing the leading role for the people to get disassociated with their personal and social schedules. And now the food is the most necessary thing to take care of. It seems the new challenge for the individual is self-isolation to maintain themselves on the health basis and fight against the pandemic situation by boosting their immunity. Food organised by proper diet may maintain the physical and mental health of the individual. Ayurveda aims to promote and preserve the health, strength and the longevity of the healthy person and to cure the disease by properly channelling with and without Ahara. In Ayurveda, diet (Ahara) is considered as one of the critical pillars of life, and Langhana plays an important role too. This article will review the relevance of dietetic approach described in Ayurveda with and without food (Asthavidhi visheshaytana & Lanhgan) during COVID-19 like a pandemic.

The Impact of COVID-19 Quarantine on Children‘s Behaviors and Language

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 796-806
Author(s):  
Sana M Kamal ◽  
Ali Al-Samydai ◽  
Rudaina Othman Yousif ◽  
Talal Aburjai
Keyword(s):  
Social Relations ◽  
Child Psychology ◽  
Simple Random Sample ◽  
Community Pharmacies ◽  
The World ◽  
Female Children ◽  
And Behavior ◽  
The Impact ◽  
Pharmaceutical Interventions

COVID-19 pandemic has spread across the world, which considered a relative of the severe acute respiratory syndrome (SARS), with possibility of transmission from animals to human and effect each of health and economic. Several preventative strategies and non-pharmaceutical interventions have been used to slow down the spread of COVID-19. The questionnaire contained 36 questions regarding the impact of COVID-19 quarantine on children`s behaviors and language have been distributed online (Google form). Data collected after asking parents about their children behavior during quarantine, among the survey completers (n=469), 42.3% were female children, and 57.7 were male children. Results showed that quarantine has an impact on children`s behaviors and language, where stress and isolationism has a higher effect, while social relations had no impact. The majority of the respondents (75.0%) had confidence that community pharmacies can play an important role in helping families in protection their children`s behaviors and language as they made the highest contact with pharmacists during quarantine. One of the main recommendations that could be applied to help parents protection and improvement their children`s behaviors and language in quarantine condition base on simple random sample opinion is increasing the role of community pharmacies inpatient counseling and especially towards children after giving courses to pharmacists in child psychology and behavior. This could be helpful to family to protect their children, from any changing in them behaviors and language in such conditions in the future if the world reface such the same problem.

Possible preventive measures against the spread of COVID-19- A Review article

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 475-481
Author(s):  
Jotheeswari P ◽  
Yuvaraj M ◽  
Balaji K ◽  
Gunapriya Raghunath ◽  
Kumaresan M
Keyword(s):  
Preventive Measures ◽  
Antiviral Drug ◽  
Preventive Measure ◽  
Thought Process ◽  
Precautionary Measure ◽  
Online Tools ◽  
The World ◽  
Base Of Support ◽  
A Current ◽  
Pharmaceutical Interventions

COVID-19 is a current sensational and dangerous threat that affects millions of people across the world. As the day progresses the rate of growth of COVID-19 drastically increases. No vaccine or specific antiviral drug are active against corona, therefore, preventing the exposure to the virus is the base of support against its spread across the world. Despite the implementation of preventive measures, the rate of virus-infected cases progressively increases which stimulates our thought process to raise a question, whether the preventive measures that we follow are effective against the spread of COVID-19 infection. Evidence from previous literature obtained from various online tools implies multiple preventive measures that should be followed and also illustrates their mechanism of action against the active spread of COVID-19 infection. According to the results from the evidence, we can identify the gold standard preventive measure among the described preventive measures. The precautionary measure encompasses both pharmaceutical interventions and non- pharmaceutical interventions among which non-pharmaceutical measures are superior in the prevention of the developing pandemic. Among the non-pharmaceutical interventions, social distancing is the paramount to other measures in the mitigation of the spread of viral infection.

Humans, common household pets and farm animals can theoretically mutually infect each other with SARS-CoV-2 and develop the COVID-19 pathology

2020 ◽  
Author(s):  
Alfredo Metere
Keyword(s):  
Empirical Evidence ◽  
Farm Animals ◽  
The World

The SARS-CoV-2 pandemic is spreading fast throughout the world, and often the new cases are reported as community spread, which means that it is not possible to identify a specific cause for contagion. Household pets and farm animals live closely to humans and even if currently there is no empirical evidence of animal to human transmission, it has not been reported yet if transmission is in principle possible. This work addresses such hypothesis, confirming that transmission is theoretically possible, and highly likely to occur between humans and mammals. Less likely or not likely at all between humans and birds. Further research is needed to validate the birds to humans transmission. -- THIS ARTICLE IS CURRENTLY BEING EXPANDED AND REVISED --

Plasma therapy a possible hope to fight against COVID-19

2020 ◽  
Author(s):  
Ravikant Piyush ◽  
Aroni Chatterjee ◽  
Shashikant Ray
Keyword(s):  
Middle East ◽  
Severe Acute Respiratory Syndrome ◽  
Viral Disease ◽  
Plasma Therapy ◽  
Therapeutic Drugs ◽  
Wild Fire ◽  
The World ◽  
Short Span ◽  
Game Changer

The world is currently going through a disastrous event and a catastrophic upheaval caused by the coronavirus disease 2019 (COVID-19). The pandemic has resulted in loss of more than 150000 deaths across the globe. Originating from China and spreading across all continents within a short span of time, it has become a matter of international emergency. Different agencies are adopting diverse approaches to stop and spread of this viral disease but still now nothing confirmatory has come up. Due to lack of vaccines and proper therapeutic drugs, the disease is still spreading like wild fire without control. An Old but very promising method- the convalescent plasma therapy could be the key therapy to stop this pandemic. This method has already proven its mettle on several occasions previously and has been found to be effective in curing the pandemics induced by Ebola, severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV). The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) belongs to the same group of β-Coronavirus that has resulted in the above diseases. Therefore, the role of plasma therapy is being explored for treatment of this disease. In this review, we have mainly focused on the role of convalescent plasma therapy and why its use should be promoted in fight against COVID-19, as it could turn out to be a game changer.

A mathematical model and an algorithm for sampling sets of components on the Assembly enterprises of space technology

2018 ◽  
Vol 15 (1) ◽  
pp. 39-55
Author(s):  
V. B. Rudakov ◽  
V. M. Makarov ◽  
M. I. Makarov
Keyword(s):  
Mathematical Model ◽  
Mathematical Models ◽  
Space Technology ◽  
Economic Costs ◽  
Problem Statement ◽  
Optimal Plan ◽  
Product Mix ◽  
Technical Parameters ◽  
Complex Products ◽  
Assembly Plants

The article considers the problem of determining the rational plans of the input sampling reliability and technical parameters of components of space technology, the totality of which is supplied to the Assembly plants for the manufacture of complex products of space technology. Problem statement and mathematical model based on the minimization of the economic costs of control and losses related to the risks of taking wrong decisions, are given in the article. The properties of the mathematical models are investigated, the algorithm for its optimization is developed. The result is an optimal plan for the sampling of sets of components, which includes: an optimal product mix subject to mandatory control of the aggregate and optimum risks of first and second kind, when acceptance number of statistical plan is zero. The latter circumstance is due to the high requirements of reliability and technical parameters of products of space technology.

Financial Literacy among Rural Women in Darbhanga District:An Empirical Evidence.

2018 ◽  
Vol 5 (1) ◽  
Author(s):  
Prof. F.B. SINGH ◽  
POOJA JHA
Keyword(s):  
Empirical Evidence ◽  
Rural Women ◽  
Financial Literacy ◽  
Rural Population ◽  
Current Status ◽  
Financial Decisions ◽  
The World ◽  
Current Scenario

Financial Literacy is defined as the possession of knowledge and understanding of elementary financial concepts which results in developing the ability to make conversant, poised and effective financial decisions. In current scenario, the concern to increase the level of financial literacy among common masses has been witnessed by many countries of the world through various Financial Literacy center, programme and initiatives but all these programmes and policies are crafted and implemented taking into consideration the male as ultimate receiver and so women who constitute half of the rural population are lagging behind in terms of a making informed financial decisions and financial wellbeing. Hence Strategies should be formulated taking into consideration the women as the main spectators. This paper is an attempt to analyze the current status of the financial literacy among the rural women of the Darbhanga district.

Modeling COVID-19 Growing Trends to Reveal the Differences in the Effectiveness of Non-Pharmaceutical Interventions among Countries in the World (Preprint)

2020 ◽  
Author(s):  
You Chen ◽  
Yubo Feng ◽  
Chao Yan ◽  
Xinmeng Zhang ◽  
Cheng Gao
Keyword(s):  
Secondary Analysis ◽  
Reproduction Rate ◽  
Cumulative Number ◽  
Linear Regression Models ◽  
Growth Data ◽  
Dynamic Changes ◽  
The World ◽  
Four Levels ◽  
Almost All ◽  
Pharmaceutical Interventions

BACKGROUND Adopting non-pharmaceutical interventions (NPIs) can affect COVID-19 growing trends, decrease the number of infected cases, and thus reduce mortality and healthcare demand. Almost all countries in the world have adopted non-pharmaceutical interventions (NPIs) to control the spread rate of COVID-19; however, it is unclear what are differences in the effectiveness of NPIs among these countries. OBJECTIVE We hypothesize that COVID-19 case growth data reveals the efficacy of NPIs. In this study, we conduct a secondary analysis of COVID-19 case growth data to compare the differences in the effectiveness of NPIs among 16 representative countries in the world. METHODS This study leverages publicly available data to learn patterns of dynamic changes in the reproduction rate for sixteen countries covering Asia, Europe, North America, South America, Australia, and Africa. Furthermore, we model the relationships between the cumulative number of cases and the dynamic reproduction rate to characterize the effectiveness of the NPIs. We learn four levels of NPIs according to their effects in the control of COVID-19 growth and categorize the 16 countries into the corresponding groups. RESULTS The dynamic changes of the reproduction rate are learned via linear regression models for all of the studied countries, with the average adjusted R-squared at 0.96 and the 95% confidence interval as [0.94 0.98]. China, South Korea, Argentina, and Australia are at the first level of NPIs, which are the most effective. Japan and Egypt are at the second level of NPIs, and Italy, Germany, France, Netherlands, and Spain, are at the third level. The US and UK have the most inefficient NPIs, and they are at the fourth level of NPIs. CONCLUSIONS COVID-19 case growth data provides evidence to demonstrate the effectiveness of the NPIs. Understanding the differences in the efficacy of the NPIs among countries in the world can give guidance for emergent public health events. CLINICALTRIAL NA

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