scholarly journals Risk factors and oral health‐Control Comparison Between Patients diagnosed with a Psychotic Disorder (First‐Episode) and People from the General Population

2022 ◽  
Author(s):  
S.A. Kuipers ◽  
S. Castelein ◽  
H. Barf ◽  
L. Kronenberg ◽  
N. Boonstra
Keyword(s):  
Risk Factors ◽  
Oral Health ◽  
General Population ◽  
Psychotic Disorder ◽  
First Episode ◽  
Health Control ◽  
Control Comparison

scholarly journals Oral health inequality in people with severe mental illness: a cross-sectional study using National Health and Nutrition Examination Survey 1999-2016

2021 ◽  
Author(s):  
Jing Kang ◽  
Jianhua Wu ◽  
Vishal Aggarwal ◽  
David Shiers ◽  
Tim Doran ◽  
...  
Keyword(s):  
Risk Factors ◽  
Mental Illness ◽  
Oral Health ◽  
General Population ◽  
Health Outcomes ◽  
Severe Mental Illness ◽  
Tooth Loss ◽  
List Type ◽  
Cross Sectional ◽  
Oral Health Outcomes

AbstractOBJECTIVETo explore whether people with severe mental illness (SMI) experience worse oral health compared to the general population, and the risk factors for poor oral health in people with SMI.METHODThis study used cross-sectional data from the National Health and Nutrition Examination Survey (1999-2016) including on self-rated oral health, ache in mouth, tooth loss, periodontitis stage, and number of decayed, missing, and filled teeth. Candidate risk factors for poor oral health included demographic characteristics, lifestyle factors, physical health comorbidities, and dental hygiene behaviours. The authors used ordinal logistic regression and zero-inflated negative binomial models to explore predictors of oral health outcomes.RESULTS53,348 cases were included in the analysis, including 718 people with SMI. In the fully adjusted model, people with SMI were more likely to suffer from tooth loss (OR 1.40, 95% CI: 1.12-1.75). In people with SMI, the risk factors identified for poor oral health outcomes were older age, white ethnicity, lower income, smoking history, and diabetes. Engaging in physical activity and daily use of dental floss were associated with better oral health outcomes.CONCLUSIONSPeople with SMI experience higher rates of tooth loss than the general population, and certain subgroups are particularly at risk. Having a healthy lifestyle such as performing regular physical exercise and flossing may lower the risk of poor oral health. These findings suggest opportunities for targeted prevention and early intervention strategies to mitigate adverse oral health outcomes.Significant outcomes (x3)People with severe mental illness were at 40% higher risk of tooth loss when compared to the general population.Older adults, smokers and people with diabetes were at particularly high risk of poor oral health.Physical exercise and daily use of dental floss were associated with better oral health outcomes.Limitations (x3)The number of cases with data on periodontal disease was limited.The study was cross-sectional so causation could not be inferred.The analysis used prescriptions of antipsychotic and mood stabilising medication as a proxy measure of severe mental illness, as clinical diagnoses were not available in the dataset.Data availability statementThe NHANES 1999-2016 data is available at CDC website: https://www.cdc.gov/nchs/nhanes/index.htm, and is accessible and free to download for everyone.

scholarly journals Metabolic risk factors in first-episode schizophrenia: baseline prevalence and course analysed from the European First-Episode Schizophrenia Trial

2013 ◽  
Vol 16 (5) ◽  
pp. 987-995 ◽  
Author(s):  
W. Wolfgang Fleischhacker ◽  
Cynthia O. Siu ◽  
Robert Bodén ◽  
Elizabeth Pappadopulos ◽  
Onur N. Karayal ◽  
...  
Keyword(s):  
Risk Factors ◽  
General Population ◽  
Prevalence Rate ◽  
Individual Risk ◽  
First Episode ◽  
Antipsychotic Treatment ◽  
Treatment Groups ◽  
Individual Risk Factors ◽  
First Episode Schizophrenia

Abstract Available data on antipsychotic-induced metabolic risks are often constrained by potential confounding effects due to prior antipsychotic treatment. In this study, we assessed the baseline prevalence of metabolic abnormalities and changes following treatment with five commonly-used antipsychotic drugs (haloperidol, amisulpride, olanzapine, quetiapine or ziprasidone) in first-episode, partially antipsychotic-naive patients with schizophrenia in the European first-episode schizophrenia trial (EUFEST). Overall baseline prevalence of metabolic syndrome (MetS) was 6.0%, with similar rates observed in the antipsychotic-naive patients (5.7%, 9/157) and in the other patients with only a brief prior exposure to antipsychotics (6.1%, 20/326). These results are consistent with the MetS prevalence rate estimated in a general population of similar age. Examination of individual risk factors showed 58.5% of subjects had one or more elevated metabolic risks at baseline: 28.5% demonstrated suboptimal HDL; 24.2% hypertension; 17.7% hypertriglyceridemia; 8.2% abdominal obesity; 7.3% hyperglycaemia. Increase in body weight (kg/month) occurred in patients treated with haloperidol (0.62 s.e. 0.11), amisulpride (0.76 s.e. 0.08), olanzapine (0.98 s.e. 0.07) and quetiapine (0.58 s.e. 0.09), which was significantly greater than that in the ziprasidone group (0.18 s.e. 0.10). The incidence rate of new diabetes cases over a 52-wk follow-up period was 0.82% (4/488). More patients experienced worsening rather than improvement of hypertriglyceridemia or hyperglycaemia in all treatment groups. Our findings suggest that in first-episode, partially antipsychotic-naive patients, the baseline prevalence rate of MetS appears to be no higher than that in the general population, but serious underlying individual risk factors nevertheless existed.

scholarly journals Prevalence of odontogenic infections and their risk factors among the general population of Hyderabad, Pakistan.

2019 ◽  
Vol 26 (11) ◽  
pp. 1931-1936
Author(s):  
Khurram Anwar ◽  
Naveed Irfan ◽  
Mudassar Iqbal Arain ◽  
Saira Shahnaz
Keyword(s):  
Risk Factors ◽  
Oral Health ◽  
Family History ◽  
Dental Caries ◽  
General Population ◽  
Periodontal Disease ◽  
Oral Hygiene ◽  
Odontogenic Infections ◽  
Dental Patients ◽  
Dental Diseases

Objectives: Oral health performs a central part in general health which is associated with good oral hygiene. Teeth and their supporting (periodontal) structures are considered most important to oral health. Therefore, Most prevalent oral diseases such as odontogenic infections (dental caries, gingivitis, periodontal disease) gum disease, oral mucosal and congenital dental problems are foremost oral health dilemma in general population. Objective: The main objective of current study was to find out the Prevalence of odontogenic infections and their risk factors among the general population. Study Design: This is a descriptive cross sectional study. Setting: Dental patients who came to different dental clinical settings of Hyderabad, Pakistan. Period: August to December 2018. Material and Methods: A total of 300 patient’s data were collected. In current study, the variables of interest are microbial odontogenic infections such as dental caries, gingivitis and periodontal disease were included in study. Following risk factors were explored: gender, age, residence, education level, disease duration, smoking, family history, and tooth paste habit. All information/data were personally collected by interview technique and oral cavity examination. The observational data were reported in the specific form and used descriptive statistics to find out the results. Results: A total of 300 dental patients having various infections such as gingivitis (47%), dental caries (20.7%) and periodontal infection (32.3%) were reported in this study. Of these, 162(54%) were females and 138(46%) of males. The most common age of patients i.e. 41.7% were from 41 to 60 years. Education status showed that 86% of the dental patients had education and 35.3% had family history of dental diseases. Factors such as mostly duration of diseases were > 6 months(33.7%) and almost 66% patients has habit of cleaning the teeths, However, Calculus and tarta deposited in 62.7% patients teeth. Smoking (21.3%) and 46.6% patients used sweet foods on daily purpose. Moreover, amoxicillin most frequently prescribed antimicrobial agent 39% followed by metronidazole 32.7%. Conclusion: Dental diseases are common public health problem among our society, poor oral hygiene & dietary habits and deposition of calculus are associated factors for odontogenic infections. Moreover, prescribing pattern shows that Amoxicillin and Metronidazole has been considered as first-line treatment for oral infections. Therefore, oral hygiene education, dietary and proper cleaning of teeth habits and dental visit at early stage of disease should be recommended for patients to avoid and cure dental odontogenic infections.

scholarly journals First incidence, age of onset outcomes and risk factors of onset of DSM-5 oppositional defiant disorder: a cohort study of Spanish children from ages 3 to 9

BMJ Open ◽  
2019 ◽  
Vol 9 (3) ◽  
pp. e022493 ◽  
Author(s):  
Lourdes Ezpeleta ◽  
J Blas Navarro ◽  
Nuria de la Osa ◽  
Eva Penelo ◽  
Josep Maria Domènech
Keyword(s):  
Risk Factors ◽  
General Population ◽  
Oppositional Defiant Disorder ◽  
Age Of Onset ◽  
Cumulative Risk ◽  
Preschool Age ◽  
First Episode ◽  
Second Phase ◽  
Oppositional Defiant ◽  
Internalising Problems

ObjectiveTo examine the 1-year first incidence and prevalence of oppositional defiant disorder (ODD), the outcomes on psychopathology and functioning by age of onset and the risk factors of onset of ODD from ages 3 to 9 in children from the Spanish general population.DesignLongitudinal with seven follow-ups and double cohort (ODD and non-ODD children).SettingGeneral population of preschool and elementary school children in Barcelona (Spain).ParticipantsOn a first phase, the parent-rated Strengths and Difficulties Questionnaire conduct problems scale plus ODD Diagnostic and Statistical Manual of Mental Disorders, fourth version, symptoms were used to screen for behavioural problems. The second phase sample size contained 622 cases at age 3 and, at age 9, 418 remained in the study.ResultsThe probability of the onset of ODD showed increasing values at ages 4 (R=2.7%) and 5 years (R=4.4%). These values decreased until age 7 (R=1.9%) and increased again until age 9 (R=3.6%). Up to 9 years old, the cumulative risk of new cases of ODD was 21.9%. Early onset was associated with a higher risk of depression comorbidity and later onset with higher functional impairment and symptomatology. Subthreshold ODD, high scores in irritability and headstrong dimensions, attention deficit/hyperactivity disorder and other comorbidity, negative affectivity until age 7, difficulties in inhibit and emotional control, punitive parenting and maternal internalising problems were risk factors of a first episode of ODD during this 7-year period.ConclusionsThe risk of new cases of ODD in the general population at preschool age and during childhood is high. Preschool age is a target period for preventive interventions. Identified risk factors are objectives for targeted and indicated interventions.

scholarly journals How to face the association between tobacco and psychosis?

10.3823/2427 ◽  
2017 ◽  
Vol 10 ◽  
Author(s):  
Raphael Tavares Dantas ◽  
Wanderley Gonçalves Cordeiro Júnior ◽  
Marcial Moreno Moreira ◽  
Lídia Coelho do Nascimento Santos ◽  
Sidney Medeiros De Oliveira ◽  
...  
Keyword(s):  
General Population ◽  
Key Words ◽  
Psychotic Disorder ◽  
Age Of Onset ◽  
Age At Onset ◽  
Mean Difference ◽  
First Episode ◽  
Psychotic Illness ◽  
Increased Risk ◽  
Key Words Tobacco

Evidences suggest an association between tobacco and psychosis. However, the reasons why people with psychosis have a higher tendency to smoke than the general population are not yet clear. Recently, Gurillo et al. reported that daily use of tobacco is associated with an increased risk of psychotic disorder and an earlier age of onset of psychotic illness. His study also calculated a significant mean difference in age at onset, expressed in years, and estimated the prevalence of smoking in people with their first episode of psychosis. According to this and other findings, it could be said that the causes of the smoking-schizophrenia association are complex and cannot be explained solely as a result of some aspect of schizophrenia. Thus, new studies in this area are needed, as well as strategies that look for the monitoring of smoking effects in order to reduce it among individuals with schizophrenia. Key-words: Tobacco, Psychosis, Illness.

Risk factors associated with treatment-resistant schizophrenia in first-episode psychosis

2017 ◽  
Vol Ano 7 ◽  
pp. 8-12
Author(s):  
Ana Beatriz de Oliveira Assis ◽  
Jayse Gimenez Pereira Brandão ◽  
Pedro Otávio Piva Espósito ◽  
Osmar Tessari Junior ◽  
Bruno Berlucci Ortiz
Keyword(s):  
Risk Factors ◽  
First Episode Psychosis ◽  
First Episode ◽  
Treatment Resistant ◽  
Factors Associated ◽  
Syndrome Scale ◽  
Episode Psychosis ◽  
Negative Syndrome

Objetivo: Ainda não está claro quais são os fatores de risco para a esquizofrenia resistente ao tratamento (ERT) em primeiro episódio psicótico (PEP). O objetivo deste trabalho é investigar indicadores de risco para ERT em PEP. Métodos: Foram selecionados 53 pacientes em primeiro episódio psicótico, com diagnóstico de esquizofrenia, que deram entrada à enfermaria de psiquiatria do Hospital das Clínicas Luzia de Pinho Melo entre 2011 e 2015. Ao ser admitido na enfermaria, o paciente era avaliado com a Escala de Sintomas para as Síndromes Positiva e Negativa (Positive and Negative Syndrome Scale – PANSS) e recebia tratamento inicial por 4 semanas. Caso sua resposta fosse inferior a 40% de redução na PANSS, o antipsicótico era trocado, e as escalas eram aplicadas novamente após mais 4 semanas. Após a falha com dois antipsicóticos, em doses plenas, por 4 semanas cada, a clozapina era introduzida, e o paciente era considerado ERT. Uma regressão logística foi aplicada onde sexo, idade de início, tempo de doença não tratada, uso de substâncias, avaliação global do funcionamento inicial e PANSS inicial total foram inseridos como variáveis independentes, e ERT foi inserida como variável dependente. Resultados: Tempo de doença não tratada apresentou significância de p = 0,038 e Exp (B) = 4,29, enquanto que PANSS total apresentou p = 0,012 e Exp (B) = 1,06. Conclusão: Identificar os fatores associados à resistência precoce ao tratamento poderia permitir aos clínicos evitar o atraso na introdução da clozapina e prevenir um pior prognóstico para esses pacientes.

Cancer in agricultural populations

2020 ◽  
pp. 837-837
Author(s):  
K. . Togawa
Keyword(s):  
Risk Factors ◽  
General Population ◽  
Cohort Studies ◽  
Health Effects ◽  
Cancer Incidence ◽  
Lower Prevalence ◽  
International Consortium ◽  
Adverse Health Effects ◽  
Specific Cancer ◽  
Cancer Types

Agricultural workers can be exposed to a wide variety of agents (e.g. pesticides), some of which may have adverse health effects, such as cancer. To study the health effects of agricultural exposures, an international consortium of agricultural cohort studies, AGRICOH, was established. The present analysis compared cancer incidence between the AGRICOH cohorts and the general population and found lower overall cancer incidence in the AGRICOH cohorts, with some variation across cohorts for specific cancer types. The observed lower cancer incidence may be due to healthy worker bias or lower prevalence of risk factors in the agricultural populations. Further analysis is underway.

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