Effect of Extraction Time on Degradation of Bioactive Compounds (Zingiber Officinale Roscoe)

2014 ◽  
Vol 67 (4) ◽  
Author(s):  
Nor Ilia Anisa Aris ◽  
Noor Azian Morad Morad

Ginger, the rhizome of Zingiber officinale contains the bioactive compounds that have a long history of medicinal usage. The two most abundant ginger bioactives identified are 6-gingerol and 6-shogaol. It is important that the availability of these bioactives are first identified. This is done through ethanol extraction. Thus, this paper identified the effect of extraction time using ethanol on the overall yield and concentration of 6-gingerol and 6-shogaol. Kinetic studies on degradation of the bioactive compounds also have been studied. Fourier transform infrared (FTIR) spectroscopy was applied as an additional tool for the characterization of the compounds and in identifying the degradation circumstances. Results showed that the highest overall yield was obtained after 8 hours of extraction. In consistent with the overall yield of extraction, the concentration of 6-gingerol and 6-shogaol reached equilibrium within 8 hours. The concentration of 6-gingerol and 6-shogaol are 13923.26 and 4816.84 μg/g, respectively. Conclusively, the saturated concentration of zingiber bioactive compounds could be determined through ethanol extraction within 8 hours.

2013 ◽  
Vol 139 (1-4) ◽  
pp. 509-514 ◽  
Author(s):  
K.L. Nagendra chari ◽  
D. Manasa ◽  
P. Srinivas ◽  
H.B. Sowbhagya

Oral Oncology ◽  
2015 ◽  
Vol 51 (5) ◽  
pp. e50 ◽  
Author(s):  
U. Kotowski ◽  
G. Heiduschka ◽  
S. Schneider ◽  
E. Enzenhofer ◽  
I. Stanisz ◽  
...  

2021 ◽  
Vol 2 (4) ◽  
pp. 576-599
Author(s):  
Andromachi Tzani ◽  
Styliani Kalafateli ◽  
Grigorios Tatsis ◽  
Maria Bairaktari ◽  
Ioanna Kostopoulou ◽  
...  

The extraction of valuable phytochemicals from natural sources is an important and constantly evolving research area. Zingiber officinale Roscoe (ginger) contains high amounts of bioactive phytochemicals, which are desirable due to their significant properties. In this work, the ability of different natural deep eutectic solvents (NaDESs) to serve as green solvents for the preparation of high added value extracts from ginger is explored, in combination with ultrasound assisted extraction. The method was optimized by applying a response surface methodology using the NaDES Bet/La/W (1:2:2.5). Three independent variables, namely the extraction time, ultrasound power and NaDES-to-dry-ginger ratio, were investigated by employing a 17-run three-level Box–Behnken Design (BBD) in order to study the correlation between the extraction conditions and the quality of the obtained extracts. The optimum conditions (in order to achieve simultaneously maximum total phenolic content and antioxidant activity), were found to be 23.8 min extraction time, 60 Watt and NaDES/ginger 25:1 w/w. In the optimum conditions the DPPH radical scavenging ability of the extracts was found to reach IC50 = 18.16 mg/mL after 120 min, whereas the TPC was 20.10 ± 0.26 mg GAE/g of dry ginger. The green methodology was also compared with the extraction using conventional solvents. All the obtained extracts were evaluated for their antioxidant activity and their total phenolic content, while the extract derived by the optimum extraction conditions was further investigated for its ability to bind to calf thymus DNA (ctDNA).


2018 ◽  
Vol 257 ◽  
pp. 223-229 ◽  
Author(s):  
Xingran Kou ◽  
Yuqian Ke ◽  
Xiaoqi Wang ◽  
Md Ramim Tanver Rahman ◽  
Yuzhang Xie ◽  
...  

2018 ◽  
Vol 39 (4) ◽  
pp. 1849
Author(s):  
Andréia Assunção Soares ◽  
Ezilda Jacomassi ◽  
Rosana Da Mata ◽  
Karoline Franciani Cardoso Lopes ◽  
Jessé Lahos Borges ◽  
...  

The functionality of nutraceutical foods is attributed to their bioactive compounds. These compounds are widely produced by plants, such as phenolic compounds, which have antioxidant activity and/or antimicrobial activity, acting against damage to macromolecules such as lipids, proteins, and nucleic acids. Secondary plant metabolites, including classes such as phenolic compounds, alkaloids, and terpenoids, have a wide variety of biological activities with medicinal potential. These secondary metabolites are considered bioactive compounds. The Zingiberaceae family received special attention for their large bioactive compound production. Such compounds are useful in foods as herbs, spices, flavorings, and seasonings and in the pharmaceutical and cosmetic industries as antioxidants and antimicrobials. Gingers are recognized as safe by the American Food and Drug Administration (FDA), resulting in no side effects when consumed in moderate amounts. Recent studies show that, in addition to rhizomes, the leaves and flowers of some ginger species have antioxidant activity and consequent medicinal potential. Studies have demonstrated that in vitro and in vivo research is needed to evaluate the efficacy of ginger extracts and understand their role in the modulation of biological and molecular pathways, thus enabling the development of new therapeutic strategies. Thereby, the present work aims to provide a bibliographic review on the antimicrobial activity of Zingiber officinale Roscoe and Alpinia purpurata (Vieill.) K. Schum. (Zingiberaceae), popularly known as ginger and red ginger respectively, and their potential use in the One Health initiative.


Food Research ◽  
2021 ◽  
Vol 5 (5) ◽  
pp. 236-243
Author(s):  
A. Sharizan ◽  
A.M. Sahilah

Zingiber officinale Roscoe var. Bentong or locally known as Bentong ginger is exclusively planted and harvested in the district of Bentong, Pahang, Malaysia. The demand for this ginger species has dramatically increased due to its high food and medicinal values, owing to the presence of 6-shogaol and 6-gingerol as active compounds. This study aimed to measure the concentrations of those active compounds with respect to their one-year plantation duration (January - December 2018). The proximate analysis, heavy metals and antioxidant activity were simultaneously determined during the plant growth. 6-gingerol was present in both fresh and dried samples whilst 6-shogaol could only be found in dried samples. Fresh ginger recorded the highest 6-gingerol content (2.09 mg/g) in the seventh month of harvesting time. On the other hand, in the sixth month of harvesting time, dried ginger had the highest concentration of 6-gingerol (0.66 mg/g) and 6-shogaol (1.85 mg/g). Notably, the accumulation of heavy metals such as As, Pb, Cd and Hg in Bentong ginger was relatively low and within the permissible limit. Meanwhile, the total polyphenol and phenolic content of Bentong ginger extract solution were observed to decrease as the ginger was maturing. In conclusion, Z. officinale Roscoe var. Bentong yielded different amounts of active compounds with respect to its harvesting time. Nevertheless, it generally exhibits good values in terms of chemical compositions that can be potentially used as nutraceutical food.


2022 ◽  
Vol 2022 ◽  
pp. 1-7
Author(s):  
Roseline Esi Amoah ◽  
Faustina Dufie Wireko-Manu ◽  
Ibok Oduro ◽  
Firibu Kwesi Saalia ◽  
William Otoo Ellis ◽  
...  

Ginger (Zingiber officinale Roscoe) rhizomes are mostly used as spice and medicine due to their high aroma intensity and medicinal bioactive compounds. However, the volatile compounds of ginger, partly responsible for its aroma and medicinal properties, can be affected by the pretreatment, drying method, and extraction processes employed. The objective of this study was to assess the effects of pretreatment and drying on the volatile compounds of yellow ginger variety at nine months of maturation. The effect of potassium metabisulfite (KMBS) and blanching pretreatment and drying on the volatile compounds of ginger using head space solid-phase microextraction with GCMS/MS identification (HS-SPME/GCMS/MS) was investigated. KMBS of concentrations 0.0 (control), 0.1, 0.15, 0.2, and 1.0% and blanching at 50°C and 100°C were used for pretreatment and dried in a tent-like concrete solar (CSD) dryer and open-sun drying (OSD). The different concentrations of KMBS-treated fresh ginger rhizomes did not result in any particular pattern for volatile compound composition identification. However, the top five compounds were mostly sesquiterpenes. The 0.15% KMBS-treated CSD emerged as the best pretreatment for retaining α-zingiberene, β-cubebene, α-farnesene, and geranial. The presence of β-cedrene, β-carene, and dihydro-α-curcumene makes this study unique. The 0.15% KMBS pretreatment and CSD drying can be adopted as an affordable alternative to preserve ginger.


Foods ◽  
2019 ◽  
Vol 8 (6) ◽  
pp. 185 ◽  
Author(s):  
Qian-Qian Mao ◽  
Xiao-Yu Xu ◽  
Shi-Yu Cao ◽  
Ren-You Gan ◽  
Harold Corke ◽  
...  

Ginger (Zingiber officinale Roscoe) is a common and widely used spice. It is rich in various chemical constituents, including phenolic compounds, terpenes, polysaccharides, lipids, organic acids, and raw fibers. The health benefits of ginger are mainly attributed to its phenolic compounds, such as gingerols and shogaols. Accumulated investigations have demonstrated that ginger possesses multiple biological activities, including antioxidant, anti-inflammatory, antimicrobial, anticancer, neuroprotective, cardiovascular protective, respiratory protective, antiobesity, antidiabetic, antinausea, and antiemetic activities. In this review, we summarize current knowledge about the bioactive compounds and bioactivities of ginger, and the mechanisms of action are also discussed. We hope that this updated review paper will attract more attention to ginger and its further applications, including its potential to be developed into functional foods or nutraceuticals for the prevention and management of chronic diseases.


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