scholarly journals Fascioliasis: An Ongoing Zoonotic Trematode Infection

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Mramba Nyindo ◽  
Abdul-Hamid Lukambagire

Zoonotic trematode infections are an area of the neglected tropical diseases that have become of major interest to global and public health due to their associated morbidity. Human fascioliasis is a trematode zoonosis of interest in public health. It affects approximately 50 million people worldwide and over 180 million are at risk of infection in both developed and underdeveloped countries. The one health paradigm is an area that seeks to address the problem of zoonotic infections through a comprehensive and sustainable approach. This review attempts to address the major challenges in managing human and animal fascioliasis with valuable insights gained from the one health paradigm to global health and multidisciplinary integration.

2021 ◽  
Author(s):  
Ayodele Oluwaseun Ajayi ◽  
Olawale Peter Odeleye ◽  
Oluwabukola Atinuke Popoola

The Covid-19 pandemic is currently ravaging the globe with enormous morbidity and mortality. This pandemic, caused by the SARS-CoV-2 started from China and has spread across the globe. Initial reports indicated that the SARS-CoV-2 initially emerged among animals from where they transfer to humans. Different strategies deployed to curtail the pandemic have yielded little result. Therefore, the One-Health concept may compliment existing strategies. The One Health places emphasis on the between the animal-human-ecosystem interface and how this can be used to tackle public health problems, including the COVID-19 pandemic. One Health Surveillance will involve tracking viral pathogens in animals to access risk of transfer to humans. It will also stimulate targeted approaches for prevention and treatment of viral zoonotic infections. There should be an integrated and interdisciplinary One-Health surveillance that should incorporate veterinary, medical or public health and environmental scientists to synergise surveillance effort to track emergence of infectious diseases in the future.


One Health ◽  
2021 ◽  
pp. 100257
Author(s):  
Chikwe Ihekweazu ◽  
Charles Akataobi Michael ◽  
Patrick M. Nguku ◽  
Ndadilnasiya Endie Waziri ◽  
Abdulrazaq Garba Habib ◽  
...  

Author(s):  
Eric Pelfrene ◽  
Radu Botgros ◽  
Marco Cavaleri

Abstract Background Antimicrobial resistance (AMR) is a growing global problem to which the ongoing COVID-19 pandemic may further contribute. With resources deployed away from antimicrobial stewardship, evidence of substantial pre-emptive antibiotic use in COVID-19 patients and indirectly, with deteriorating economic conditions fuelling poverty potentially impacting on levels of resistance, AMR threat remains significant. Main body In this paper, main AMR countermeasures are revisited and priorities to tackle the issue are re-iterated. The need for collaboration is stressed, acknowledging the relationship between human health, animal health and environment (“One Health” approach). Among the stated priorities, the initiative by the European Medicines Regulatory Network to further strengthen the measures in combatting AMR is highlighted. Likewise, it is asserted that other emerging health threats require global collaboration with the One Health approach offering a valuable blueprint for action. Conclusion The authors stress the importance of an integrated preparedness strategy to tackle this public health peril.


2021 ◽  
Author(s):  
Christian Selbach ◽  
Maarten P. M. Vanhove ◽  
Kim Nørgaard Mouritsen

The One Health concept offers an integrative approach to disease and health at the human-animal-environment interface. It has often been suggested to view the COVID-19 outbreak within this framework to better understand and mitigate this global crisis. Here, we discuss how the evolutionary ecology of host-pathogen systems can add a valuable additional perspective to the debate around SARS-CoV-2 and its implications for public health awareness and policy-making. In this context, it is especially important to highlight that changes in nature, such as zoonotic spillover events, are often irreversible, and that humans, while deeply embedded in ecosystems, are intricate ecosystems themselves. A better recognition of the complex biology and evolution of human-parasite interactions will assist our understanding of such zoonoses.


2016 ◽  
Vol 15 (2) ◽  
pp. 107-120
Author(s):  
Andrea Győrffy ◽  
Ákos Jozwiak

Public health belongs to the “One Health” umbrella. As military veterinary medicine evolved, it became embedded in national security. Many armed forces still have active veterinary services, both regular and reserve components. The military veterinarian can serve as an interface between civilians and civil organizations, can handle complex and interdisciplinary cases. Introducing the “One Health” concept both in practice and education has encountered many difficulties. Over time, “One Health” has been judged to be a “buzz word” in civilian areas; however, it is a weighty concept. Its importance is pronounced in military areas where practicing along One Health principles were present before the appearance of the term itself. Nevertheless, military “One Health” has not penetrated into the overwhelming “One Health” literature. Emphasizing the military aspects of One Health not only reveals an obscure corner but might help to regain the proper importance of the “One Health” concept.


Animals ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 2377
Author(s):  
Valentina Zappulli ◽  
Silvia Ferro ◽  
Federico Bonsembiante ◽  
Ginevra Brocca ◽  
Alessandro Calore ◽  
...  

Coronaviruses (CoVs) are worldwide distributed RNA-viruses affecting several species, including humans, and causing a broad spectrum of diseases. Historically, they have not been considered a severe threat to public health until two outbreaks of COVs-related atypical human pneumonia derived from animal hosts appeared in 2002 and in 2012. The concern related to CoVs infection dramatically rose after the COVID-19 global outbreak, for which a spill-over from wild animals is also most likely. In light of this CoV zoonotic risk, and their ability to adapt to new species and dramatically spread, it appears pivotal to understand the pathophysiology and mechanisms of tissue injury of known CoVs within the “One-Health” concept. This review specifically describes all CoVs diseases in animals, schematically representing the tissue damage and summarizing the major lesions in an attempt to compare and put them in relation, also with human infections. Some information on pathogenesis and genetic diversity is also included. Investigating the lesions and distribution of CoVs can be crucial to understand and monitor the evolution of these viruses as well as of other pathogens and to further deepen the pathogenesis and transmission of this disease to help public health preventive measures and therapies.


One Health ◽  
2017 ◽  
Vol 3 ◽  
pp. 1-4 ◽  
Author(s):  
C. Robinette ◽  
L. Saffran ◽  
A. Ruple ◽  
S.L. Deem
Keyword(s):  

Genes ◽  
2018 ◽  
Vol 9 (7) ◽  
pp. 359 ◽  
Author(s):  
Eta Ashu ◽  
Jianping Xu

The United Nations’ One Health initiative advocates the collaboration of multiple sectors within the global and local health authorities toward the goal of better public health management outcomes. The emerging global health threat posed by Aspergillus species is an example of a management challenge that would benefit from the One Health approach. In this paper, we explore the potential role of molecular epidemiology in Aspergillus threat management and strengthening of the One Health initiative. Effective management of Aspergillus at a public health level requires the development of rapid and accurate diagnostic tools to not only identify the infecting pathogen to species level, but also to the level of individual genotype, including drug susceptibility patterns. While a variety of molecular methods have been developed for Aspergillus diagnosis, their use at below-species level in clinical settings has been very limited, especially in resource-poor countries and regions. Here we provide a framework for Aspergillus threat management and describe how molecular epidemiology and experimental evolution methods could be used for predicting resistance through drug exposure. Our analyses highlight the need for standardization of loci and methods used for molecular diagnostics, and surveillance across Aspergillus species and geographic regions. Such standardization will enable comparisons at national and global levels and through the One Health approach, strengthen Aspergillus threat management efforts.


Pathogens ◽  
2021 ◽  
Vol 10 (11) ◽  
pp. 1355
Author(s):  
Valerio M. Sora ◽  
Gabriele Meroni ◽  
Piera A. Martino ◽  
Alessio Soggiu ◽  
Luigi Bonizzi ◽  
...  

The One Health approach emphasizes the importance of antimicrobial resistance (AMR) as a major concern both in public health and in food animal production systems. As a general classification, E. coli can be distinguished based on the ability to cause infection of the gastrointestinal system (IPEC) or outside of it (ExPEC). Among the different pathogens, E. coli are becoming of great importance, and it has been suggested that ExPEC may harbor resistance genes that may be transferred to pathogenic or opportunistic bacteria. ExPEC strains are versatile bacteria that can cause urinary tract, bloodstream, prostate, and other infections at non-intestinal sites. In this context of rapidly increasing multidrug-resistance worldwide and a diminishingly effective antimicrobial arsenal to tackle resistant strains. ExPEC infections are now a serious public health threat worldwide. However, the clinical and economic impact of these infections and their optimal management are challenging, and consequently, there is an increasing awareness of the importance of ExPECs amongst healthcare professionals and the general public alike. This review aims to describe pathotype characteristics of ExPEC to increase our knowledge of these bacteria and, consequently, to increase our chances to control them and reduce the risk for AMR, following a One Health approach.


Author(s):  
Gabrielle Laing ◽  
Marco Antonio Natal Vigilato ◽  
Sarah Cleaveland ◽  
S M Thumbi ◽  
Lucille Blumberg ◽  
...  

Abstract The forthcoming World Health Organization road map for neglected tropical diseases (NTDs) 2021–2030 recognises the complexity surrounding control and elimination of these 20 diseases of poverty. It emphasises the need for a paradigm shift from disease-specific interventions to holistic cross-cutting approaches coordinating with adjacent disciplines. The One Health approach exemplifies this shift, extending beyond a conventional model of zoonotic disease control to consider the interactions of human and animal health systems within their shared environment and the wider social and economic context. This approach can also promote sustainability and resilience within these systems. To achieve the global ambition on NTD elimination and control, political will, along with contextualised innovative scientific strategies, is required.


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