scholarly journals Pancreatoduodenectomy for Periampullary Tumors Presenting with Acute Pancreatitis

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Xuefeng Cao ◽  
Xixiu Wang ◽  
Xiaoliang Xu ◽  
Yanmin Lu ◽  
Baolei Zhao ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Operative Time ◽  
Laboratory Data ◽  
Biliary Fistula ◽  
University Hospital ◽  
Control Group ◽  
Study Group ◽  
Course Of Disease ◽  
Periampullary Tumors ◽  
Medical University

Background. Periampullary tumors (PT) may rarely present as acute pancreatitis (AP) or acute recurrent pancreatitis (ARP). Unlike other cases of AP and ARP, these conditions necessitate pancreaticoduodenectomy (PD), and timely diagnosis is crucial. Materials and Methods. A retrospective review of clinical, radiological, surgical, and pathological data was conducted for patients admitted to the Binzhou Medical University Hospital during the period from January 2010 to December 2017, for AP or ARP caused by PT. All patients included in the study group had undergone PD. The perioperative data for these patients was compared with data for patients with PT but without AP or ARP who underwent PD during the same period (control group). Results. During the study period, 412 patients with AP or ARP were treated; among this group, 15 patients had PT. Compared with controls, patients in the study group were younger in age and had a longer course of disease, more frequent hospitalizations, and more severe derangements in laboratory data (P<0.05). Operative time and intraoperative blood loss were significantly higher in the study group, but the incidence of postoperative outcomes such as pancreatic/biliary fistula, abdominal infection, postoperative hospital stay, and mortality were similar between groups (P>0.05). Conclusions. Neither AP nor ARP has any adverse impact on the outcomes of PD. However, in the treatment of younger patients suffering from AP or ARP, unexplained pancreatic duct dilation and weight loss should raise the suspicion of PT. EUS and EUS-FNA may be helpful in making the diagnosis.

scholarly journals Aerobic Vaginitis—Underestimated Risk Factor for Cervical Intraepithelial Neoplasia

Diagnostics ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 97
Author(s):  
Olga Plisko ◽  
Jana Zodzika ◽  
Irina Jermakova ◽  
Kristine Pcolkina ◽  
Amanda Prusakevica ◽  
...  
Keyword(s):  
Histological Finding ◽  
Intraepithelial Neoplasia ◽  
Vaginal Microbiota ◽  
University Hospital ◽  
Control Group ◽  
Study Group ◽  
Aerobic Vaginitis ◽  
Abnormal Cervical Cytology ◽  
Low Education ◽  
Independent Risk Factors

The aim of this study is to analyse the association between vaginal microbiota and the histological finding of CIN. From July 2016 until June 2017, we included 110 consecutive patients with abnormal cervical cytology results referred for colposcopy to Riga East Clinical University Hospital Outpatient department in the study group. 118 women without cervical pathology were chosen as controls. Certified colposcopists performed interviews, gynaecological examinations and colposcopies for all participants. Material from the upper vaginal fornix was taken for pH measurement and wet-mount microscopy. Cervical biopsy samples were taken from all subjects in the study group and in case of a visual suspicion for CIN in the control group. Cervical pathology was more often associated with smoking (34.6% vs. 11.0%, p < 0.0001), low education level (47.2% vs. 25.5%, p = 0.001), increased vaginal pH (48.2% vs. 25.4%, p < 0.0001), abnormal vaginal microbiota (50% vs. 31.4%, p = 0.004) and moderate to severe aerobic vaginitis (msAV) (13.6% vs. 5.9%, p = 0.049) compared to controls. The most important independent risk factors associated with CIN2+ were smoking (OR 3.04 (95% CI 1.37–6.76), p = 0.006) and msAV (OR 3.18 (95% CI 1.13–8.93), p = 0.028). Bacterial vaginosis (BV) was found more often in CIN1 patients (8/31, 25.8%, p = 0.009) compared with healthy controls (8/118, 6.8%), or CIN2+ cases (8/79, 10.1%). In the current study msAV and smoking were the most significant factors in the development of CIN in HPV-infected women, especially high grade CIN. We suggest that AV changes are probably more important than the presence of BV in the pathogenesis of CIN and progression to cervix cancer and should not be ignored during the evaluation of the vaginal microbiota.

scholarly journals Effect of Tooth Agenesis on Mandibular Morphology and Position

2021 ◽  
Vol 18 (22) ◽  
pp. 11876
Author(s):  
Agnieszka Jurek ◽  
Dariusz Gozdowski ◽  
Ewa Monika Czochrowska ◽  
Małgorzata Zadurska
Keyword(s):  
Permanent Tooth ◽  
Control Group ◽  
Tooth Agenesis ◽  
Study Group ◽  
Mandibular Position ◽  
Mandibular Body ◽  
Dental Abnormality ◽  
And Gender ◽  
Medical University ◽  
Tooth Buds

Congenital missing teeth (OMIM #106600) is the most common dental abnormality. The aim of the study was to evaluate the effects of tooth agenesis on the total mandibular length, length of the mandibular body and alveolar process, and the mandibular anteroposterior position. The material was obtained from the Department of Orthodontics, Medical University of Warsaw. The study group included 116 patients aged 9–18 years with a congenital absence of at least two permanent tooth buds in the maxilla and/or mandible (mean: 6.2 teeth missing/patient). All patients were Caucasians: 68 (59%) females and 48 (41%) males. The control group included 115 patients without tooth agenesis matched with the age and gender of the study group. A cephalometric analysis was performed, and it was focused on assessing anteroposterior mandibular measurements. This assessment was based on 17 measurements (12 linear and 5 angular). Statistical analysis of the cephalometric measurements between the study group and the control group showed significant changes regarding selected mandibular measurements. Tooth agenesis does not affect the total length of the mandible and the length of the mandibular body, but it might reduce the length of the mandibular arch length and result in a more retrusive mandibular position.

scholarly journals EFFECTS OF THE SCHROTH METHOD FOR TRUNK MUSCLES’ STATIC ENDURANCE AND SPINE MOBILITY IN GIRLS WITH IDIOPATHIC SCOLIOSIS

2017 ◽  
Vol 27 (5) ◽  
pp. 71-75
Author(s):  
Vaiva Strukčinskaitė ◽  
Juozas Raistenskis ◽  
Aurelija Šidlauskienė ◽  
Birutė Strukčinskienė ◽  
Sigitas Griškonis
Keyword(s):  
Idiopathic Scoliosis ◽  
Treatment Method ◽  
University Hospital ◽  
Trunk Muscles ◽  
Control Group ◽  
Abdominal Muscles ◽  
Study Group ◽  
Trunk Flexion ◽  
Rehabilitation Centre ◽  
Spine Mobility

The prevalence of scoliosis in the paediatric population is increasing every year. The treatment of idiopathic scoliosis in Lithuania is based on traditional physical therapy, and it is not always the most effective. Schroth method recently is widely globally used evidence-based conservative scoliosis treatment method. The aim of the study was to assess the effects of the Schroth method treatment for trunk muscles’ static endurance and spine mobility in girls with idiopathic scoliosis. The study was conducted in 2016-2017 at the Physical Medicine and Rehabilitation Centre, Children’s Hospital, Affiliate of Vilnius University Hospital Santaros Klinikos. In the study participated 50 girls aged 9-17 years with idiopathic scoliosis. The patients were divided into two groups: the study group (n = 25) and the control group (n = 25). Schroth treatment method for the study group and a traditional physiotherapy for the control group were used. For patients were applied 10 procedures of physiotherapy (for 30 minutes, 5 times a week). The study showed that trunk muscles’ static endurance results after rehabilitation were significantly higher in the study group than in the control group (p&lt;0.05). The analysis of the average changes in the results between the groups revealed that in the study group the results of abdominal muscles (16.08 s more), left side trunk muscles (6.98 s more), and right side trunk muscles (7.84 s more) had changed significantly. Results of spine mobility significantly improved in both groups after rehabilitation (p&lt;0.05). Trunk flexion amplitude estimated to have significantly greater improvement in the study group. The treatment using Schroth method had significantly improved the indicators of trunk muscles’ static endurance and mobility of the spine during spinal flexion. When compare the results inside the groups, the significant change was shown in the majority of spine and posture-related parameters in the study group. Special physiotherapy, especially Schroth method for children with idiopathic scoliosis have been shown to be an effective conservative treatment for scoliosis.

Squamous Epithelium in the Middle Ear and Sinus

1994 ◽  
Vol 73 (1) ◽  
pp. 47-48
Author(s):  
Alper Tutkun ◽  
Caglar Batman ◽  
Cüneyt Üneri ◽  
Mehmet Ali Sehitoglu
Keyword(s):  
Middle Ear ◽  
Statistical Difference ◽  
Squamous Epithelium ◽  
Normal Skin ◽  
University Hospital ◽  
Control Group ◽  
Study Group ◽  
External Ear ◽  
Ear Canal ◽  
Superior Part

This study has been performed between December 1990—March 1991 in the Microsurgery laboratory of the Marmara University Hospital. Twelve healthy albino guinea pigs were used as a study group while the control group consists of three animals. The potentials for cholesteatoma formation of the squamous epithelium, namely the squamous epithelium of the posterior superior part of the external ear canal skin and normal skin, were investigated. Among 24 subjects who were implanted by canal skin, cholesteatoma was fanned in 21 of them. Likewise, 19 of 24 animals implanted by normal skin came out with cholesteatoma formation. Between these two types of epithelium, there is no statistical difference in cholesteatoma formation (p >0.5).

Dynamic thiol/disulphide homeostasis metrics as a risk factor for peripheral arterial disease

Vascular ◽  
2020 ◽  
pp. 170853812094724
Author(s):  
Ufuk Turan Kursat Korkmaz ◽  
Ahmet Yuksel ◽  
Ayhan Cetinkaya ◽  
Yusuf Velioglu ◽  
Erhan Renan Ucaroglu ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Risk Factor ◽  
Peripheral Arterial Disease ◽  
Laboratory Data ◽  
Arterial Disease ◽  
Control Group ◽  
Study Group ◽  
Total Thiol ◽  
Peripheral Arterial ◽  
Study Participants

Objective To examine dynamic thiol/disulphide homeostasis metrics as a novel risk factor of oxidative stress in patients with peripheral arterial disease. Methods One hundred patients with lower extremity peripheral arterial disease (a study group) and 100 control subjects were included in this prospective case–control study. Participants’ baseline clinical characteristics and laboratory data including some oxidant/antioxidant status parameters such as albumin, ferroxidase and myeloperoxidase, and thiol/disulphide homeostasis parameters such as native thiol, total thiol and disulphide, as well as native thiol/total thiol, disulphide/native thiol and disulphide/total thiol ratios were all recorded and then compared between the groups. Results Mean albumin and ferroxidase, and median myeloperoxidase levels were found to be significantly higher in patients with the peripheral arterial disease than in control group ( p = 0.045, p = 0.000 and p = 0.000, respectively). Mean native thiol and total thiol, and median disulphide levels were found to be significantly lower in the study group as compared with the control group ( p = 0.000, p = 0.000 and p = 0.037, respectively). According to the results of logistic regression analysis, systolic blood pressure, ferroxidase and myeloperoxidase levels were detected to be the independent predictors of peripheral arterial disease. Conclusion Our report is the first one in the literature investigating dynamic thiol/disulphide homeostasis metrics as a novel risk factor of oxidative stress in peripheral arterial disease. Dynamic thiol/disulphide homeostasis metrics may be used as a valuable risk factor of oxidative stress in patients with the peripheral arterial disease since it is readily available, easily calculated and relatively cheap.

scholarly journals The nutritional status of nurses working shifts: A pilot study in Turkey

2016 ◽  
Vol 29 (4) ◽  
pp. 589-596 ◽  
Author(s):  
Semra NAVRUZ VARLI ◽  
Saniye BILICI
Keyword(s):  
Nutritional Status ◽  
Night Shift ◽  
Study Data ◽  
University Hospital ◽  
Control Group ◽  
Study Group ◽  
Food Services ◽  
Food Record ◽  
The Mean ◽  
Female Nurses

ABSTRACT Objective: This study was carried out to determine the nutritional status of shift-working female nurses at a university hospital in Ankara, Turkey. Methods: A total of 110 volunteer female nurses (n=56 control group, n=54 study group) were included in the study. A questionnaire with a three day food record collected the study data. Results: The mean daily energy intake of the study group was higher than that of the control group (1756±659 kcal versus 1694±431 kcal, p>0.05). While the carbohydrate intake (196.3±85.5 g versus 185.9±54.7 g) and fat intake (79.5±29.5 g versus 77.1±22.6 g) were higher in the study group, the protein intake was higher in the control group (59.4±17.6 g versus 57.6±21.6 g). The mean iron intake was statistically higher in the control group (10.6±2.9 mg versus 10.0±4.0 mg, p<0.05). Conclusion: To improve night shift workers' performance and nutritional status it is important to provide accessible, healthy, and quality food services.

Prognostic value of mean platelet volume on tinnitus

2015 ◽  
Vol 130 (2) ◽  
pp. 162-165 ◽  
Author(s):  
O Kemal ◽  
T Müderris ◽  
F Başar ◽  
G Kutlar ◽  
F Gül
Keyword(s):  
Mean Platelet Volume ◽  
Healthy Subjects ◽  
Clinical Findings ◽  
University Hospital ◽  
Control Group ◽  
Study Group ◽  
Pathophysiological Mechanism ◽  
Platelet Volume ◽  
Significant Difference ◽  
Healthy Control

AbstractObjective:This study aimed to determine whether there was any relationship between tinnitus and mean platelet volume.Methods:This retrospective study was conducted between January 2013 and January 2014 in Ankara Atatürk Hospital and Ondokuz Mayıs University Hospital, Turkey, on a study group of 86 patients with tinnitus and a control group of 84 healthy subjects. Mean platelet volume was recorded and comparisons were made between the two groups.Results:Mean (± standard deviation) platelet volume was 7.67 ± 0.83 μm3 in the study group and 7.28 ± 0.56 μm3 in the control group. There was a statistically significant difference in mean platelet volume between the tinnitus patients and the healthy subjects (p < 0.05).Conclusion:The clinical findings indicated that tinnitus patients had a higher mean platelet volume than the healthy control subjects; however, the pathophysiological mechanism remains unclear.

scholarly journals EFFECTIVENESS OF PROSTHODONTIC TREATMENT OF PATIENTS WITH INCREASED DENTAL ATTRITION ON THE BASIS OF FUNCTIONAL DIAGNOSTIC

2018 ◽  
Vol 22 (6) ◽  
pp. 297-300
Author(s):  
Alexander S. Romanov ◽  
V. G Morozov ◽  
P. N Geletin
Keyword(s):  
Dental Treatment ◽  
University Hospital ◽  
Control Group ◽  
Dental Attrition ◽  
Before And After ◽  
Medical University ◽  
Methods Of Treatment ◽  
Functional Diagnostic ◽  
Group 1

Aim of the present study was to evaluate the effectiveness of prosthodontic methods of treatment based of functional diagnostic of patients with increased dental attrition Methods. We have examined 35 patients at the Smolensk State Medical University Hospital: 20 patients with increased dental attrition and 15 patients who didn’t have any sign of functional disorders of dentoalveolar and musculoskeletal system. The main group was divided into two subgroups. In the group 1 (11 patients) required a prosthodontic therapy included individual wax-up of future prosthetic construction based on data of functional diagnostic. An electromyographic study was conducted before and one month after treatment for determination of the effectiveness of treatment methods. Results. Analyzing and comparing the data of the electromyographic study 1 month before and after treatment of patients of the 1 group have shown 93,1 % effectiveness of the treatment and the control group. The results of the study show that such occlusion is optimal for the muscles and temporomandibular joint. Conclusion. Dental treatment of increased attrition of teeth based on functional diagnostic contributes to the normalization of muscles activity. Moreover it allows to protect teeth from attrition and providing effective rehabilitation of patients.

scholarly journals The effect of enteral nutrition on intra-abdominal pressure in severe acute pancreatitis patients

2017 ◽  
Author(s):  
Mingjie Zhang ◽  
Li-Ping Cao ◽  
Guoping Ding
Keyword(s):  
Acute Pancreatitis ◽  
Enteral Nutrition ◽  
Severe Acute Pancreatitis ◽  
Occurrence Rate ◽  
Control Group ◽  
Abdominal Pressure ◽  
Therapeutic Effects ◽  
Study Group ◽  
Time Operation ◽  
Operation Rate

Abstract BACKGROUND: To investigate the effect of enteral nutrition (EN) on intra-abdominal pressure (IAP) in severe acute pancreatitis (SAP) patients and the relationship between the decreasion of IAP and the the therapeutic effect of EN. METHODS: Eighty SAP patients were randomly divided into study group and control group (40 patients in each group). Patients in the study group received EN and Patients in the control group received total parenteral nutrition (TPN) for 7 days. Intra-cystic pressure (ICP) of the two groups was measured during treatment period. The outcomes of treatment were observed, APACHE Ⅱ scores, NB data were applied in analysis. RESULTS: The ICP data was lower in the study group than in the control group on days 4 and 5 of treatment (P &lt; 0.05). On days 3-5 of treatment, the APACHE Ⅱ scores of the study group were lower than which of the control group (P &lt; 0.05). Nitrogen balance (NB) date increased significantly in study group than in the control group (P &lt; 0.05). abdominalgia relief time, operation rate were different between the two groups (P &lt; 0.05). The abdominal compartment syndrome (ACS) occurrence rate of the two groups have no significant difference. The ICP data and APACHE Ⅱscores, abdominalgia relief time, operation rate of pancreas debridement show positive correlation (P &lt; 0.05). ICP and NB date show negative correlation (P &lt; 0.05). CONCLUSION: EN can decrease the IAP of SAP, which may be the reason for EN show preventive and therapeutic effects on SAP.

Chemoprophylaxis of Recurrent Otitis Media Using Trimethoprim/Sulfamethoxazole

1982 ◽  
Vol 16 (5) ◽  
pp. 387-390 ◽  
Author(s):  
John D. Gaskins ◽  
Robert J. Holt ◽  
Catherine U. Kyong ◽  
C. Wayne Weart ◽  
James Ward
Keyword(s):  
High Risk ◽  
Otitis Media ◽  
Pediatric Population ◽  
Acute Otitis Media ◽  
Early Spring ◽  
Control Group ◽  
Study Group ◽  
Chi Square ◽  
Exact Test ◽  
Medical University

This study was undertaken during the late fall, winter, and early spring months to determine the efficacy of daily trimethoprim/sulfamethoxazole (TMP/SMX) administration in the prevention of recurrent acute otitis media (RAOM) in a specific high-risk pediatric population. Twenty-one ambulatory patients, 10 in the study group and 11 in the control group, were selected from a medical university clinic and a local private practice. The study group receiving prophylactic therapy for six months suffered no recurrences, as compared with eight children suffering one recurrence each in the control group that was treated only acutely. The results were significant at p <0.005 with df = 1, determined by the Fischer's exact test and the chi-square method using Yates's correction factor. These data indicated that a mean dose of TMP/SMX 6.8/34 mg/kg/d divided into twice daily doses and given for six months was safe and effective in controlling RAOM infections in a high-risk pediatric population.

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