scholarly journals Comparison of Effects of Radiofrequency Ablation of Liver Cancer Guided by CT Images Based on Deep Learning Algorithm

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Kai Huang ◽  
Tongqing Zhang ◽  
Zhiliang He ◽  
Fengxia Wang
Keyword(s):  
Deep Learning ◽  
Liver Cancer ◽  
Primary Liver Cancer ◽  
Operation Time ◽  
Spiral Ct ◽  
Postoperative Hospital Stay ◽  
Liver Lesions ◽  
Ct Guided ◽  
Total Operation Time ◽  
Significant Difference

Objective. To investigate the paper radiofrequency ablation (RFA) CT-guided feasibility of hepatocellular carcinoma (primary liver cancer) treatment, safety, and clinical efficacy of the use of deep learning algorithms. Method. A total of 47 cases of primary liver cancer patients were included: 21 cases of CT-guided liver lesions in line with RFA (C-CT group) and, in the same period, 26 cases of spiral CT-guided liver lesions in line with RFA (S-CT group). Two groups of patients were recorded immediately after the total operation time and ablation time, the acceptable radiation dose was observed in the incidence of postoperative complications of 7d, and the postoperative hospital stay was recorded to evaluate the efficacy of the treatment of lesions in 1, 3, and 6 months after RFA. Results. All 47 patients were successful; two technical success rates were 100%. There was a significant difference ( P  < 0.05) in the total operation time groups, ablation time, and acceptable radiation dose. And there was no significant difference ( P  < 0.05) in postoperative complications of 7d groups, postoperative hospital stay, and local disease control. There was a significant difference ( P  < 0.05) in the S-CT group, seven ablation residual or recurrent lesions during the follow-up ratio of 26.9%, and C-CT groups compared with only 14.3%. Conclusion. CT-guided RFA treatment of primary liver cancer patients is safe, effective, and superior to the conventional spiral CT-guided ablation lesion site-specific terms.

Comparative the clinical value of contrast-enhanced ultrasonography, enhancement CT and MRI for diagnosing of liver lesions

2021 ◽  
pp. 1-11
Author(s):  
Gang Zhang ◽  
Dandan Liu
Keyword(s):  
Liver Cancer ◽  
Primary Liver Cancer ◽  
Pathological Examination ◽  
Liver Lesions ◽  
Clinical Value ◽  
Contrast Enhanced ◽  
Enhanced Ct ◽  
Significant Difference ◽  
Contrast Enhanced Ultrasonography ◽  
Ct And Mri

BACKGROUND: To investigate the accuracy of contrast-enhanced ultrasonography, CT-enhancement and MRI in the diagnosis of liver-occupying lesions. METHODS: 176 patients with suspected liver lesions in our hospital were retrospectively studied from July 2014 to July 2016. All of the 176 patients were diagnosed by contrast-enhanced ultrasonography, enhanced CT and MRI, and the pathological examination was performed. The results of pathological examination were regarded as the results of the diagnosis. The diagnostic accuracywas then compared among contrast-enhanced ultrasound, enhanced CT and MRI of these patients. RESULTS: The results of contrast-enhanced ultrasonography showed that 164 of the 176 patients had liver-occupying lesions, and the accuracy of the diagnosis was 95.35%, which was significantly higher than that of CT enhancement and MRI (80.23% 84.30%). The accuracy of contrast-enhanced ultrasonography, in the diagnosis of primary liver cancer was significantly higher than that of CT enhancement and MRI (P <  0.05), and the difference was significant difference (P <  0.05). CONCLUSIONS: The examination of contrast-enhanced ultrasonography is relatively simple, and the patients can get duplicateexamination, so we should choose the contrast-enhanced ultrasonography as the preferred method of diagnosis in liver mass, especially primary liver cancer.

scholarly journals Intelligent Algorithm-Based Magnetic Resonance Imaging in Radical Gastrectomy under Laparoscope

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Wenkui Mo ◽  
Cansong Zhao
Keyword(s):  
Gastric Cancer ◽  
Operation Time ◽  
Laparoscopic Group ◽  
Postoperative Hospital Stay ◽  
Intraoperative Blood Loss ◽  
Resonance Imaging ◽  
Intelligent Algorithm ◽  
Short Term ◽  
Laparoscopy Group ◽  
Significant Difference

The study focused on the influence of intelligent algorithm-based magnetic resonance imaging (MRI) on short-term curative effects of laparoscopic radical gastrectomy for gastric cancer. A convolutional neural network- (CNN-) based algorithm was used to segment MRI images of patients with gastric cancer, and 158 subjects admitted at hospital were selected as research subjects and randomly divided into the 3D laparoscopy group and 2D laparoscopy group, with 79 cases in each group. The two groups were compared for operation time, intraoperative blood loss, number of dissected lymph nodes, exhaust time, time to get out of bed, postoperative hospital stay, and postoperative complications. The results showed that the CNN-based algorithm had high accuracy with clear contours. The similarity coefficient (DSC) was 0.89, the sensitivity was 0.93, and the average time to process an image was 1.1 min. The 3D laparoscopic group had shorter operation time (86.3 ± 21.0 min vs. 98 ± 23.3 min) and less intraoperative blood loss (200 ± 27.6 mL vs. 209 ± 29.8 mL) than the 2D laparoscopic group, and the difference was statistically significant ( P < 0.05 ). The number of dissected lymph nodes was 38.4 ± 8.5 in the 3D group and 36.1 ± 6.0 in the 2D group, showing no statistically significant difference ( P > 0.05 ). At the same time, no statistically significant difference was noted in postoperative exhaust time, time to get out of bed, postoperative hospital stay, and the incidence of complications ( P > 0.05 ). It was concluded that the algorithm in this study can accurately segment the target area, providing a basis for the preoperative examination of gastric cancer, and that 3D laparoscopic surgery can shorten the operation time and reduce intraoperative bleeding, while achieving similar short-term curative effects to 2D laparoscopy.

scholarly journals Effects of radiofrequency ablation assisted partial hepatectomy in the treatment of primary liver cancer

2017 ◽  
Vol 1 (3) ◽  
Author(s):  
Yongbo Wang
Keyword(s):  
Radiofrequency Ablation ◽  
Postoperative Complications ◽  
Liver Cancer ◽  
Partial Hepatectomy ◽  
Primary Liver Cancer ◽  
Length Of Hospital Stay ◽  
Operation Time ◽  
Control Group ◽  
Study Group ◽  
Postoperative Length

Objective: To investigate the effects of radiofrequency ablation assisted partial hepatectomy in the treatment of primary liver cancer. Methods: A total of 60 patients with primary liver cancer treated in our hospital from March 2013 to October 2015 were selected as study subjects and were divided into the control group and the study group by the random number table method, 30 cases in each group. The control group were treated with partial hepatectomy. On the basis, the study group were treated with radiofrequency ablation. The operation associated indexes (operation time, the average wound bleeding volume, postoperative length of hospital stay), preoperative and postoperative liver function indexes [alanine aminotransferase (ALT), total bilirubin (TBIL), aspartate aminotransferase (AST)], the incidence of complications and recurrence rates in the two groups were observed. Results: The operation time and postoperative length of hospital stay of the study group were significantly shorter than those of the control group, and the average bleeding volume was significantly less than that of the control group (P < 0.05). There was no significant difference in ALT, TBiL and AST between the two groups before operation(P>0.05). After operation, ALT, TBiL and AST in the two groups were significantly lower than those before operation, and the changes in the study group were greater than those in the control group (P < 0.05). The incidence of postoperative complications and the recurrence rate in 1 year after operation were significantly  lower than those in the control group (P < 0.05). Conclusion: Radiofrequency ablation has obvious positive effect in patients with primary liver cancer undergoing partial hepatectomy. It has advantages of little bleeding, short rehabilitation time, protecting liver function, few postoperative complications and low recurrence rate.

scholarly journals A Novel Bio-Inspired Deep Learning Approach for Liver Cancer Diagnosis

Information ◽  
2020 ◽  
Vol 11 (2) ◽  
pp. 80 ◽  
Author(s):  
Rania M. Ghoniem
Keyword(s):  
Deep Learning ◽  
Liver Cancer ◽  
State Of The Art ◽  
The State ◽  
Convergence Time ◽  
Computational Time ◽  
Learning Approach ◽  
Liver Lesions ◽  
Learning Models ◽  
Abc Algorithm

Current research on computer-aided diagnosis (CAD) of liver cancer is based on traditional feature engineering methods, which have several drawbacks including redundant features and high computational cost. Recent deep learning models overcome these problems by implicitly capturing intricate structures from large-scale medical image data. However, they are still affected by network hyperparameters and topology. Hence, the state of the art in this area can be further optimized by integrating bio-inspired concepts into deep learning models. This work proposes a novel bio-inspired deep learning approach for optimizing predictive results of liver cancer. This approach contributes to the literature in two ways. Firstly, a novel hybrid segmentation algorithm is proposed to extract liver lesions from computed tomography (CT) images using SegNet network, UNet network, and artificial bee colony optimization (ABC), namely, SegNet-UNet-ABC. This algorithm uses the SegNet for separating liver from the abdominal CT scan, then the UNet is used to extract lesions from the liver. In parallel, the ABC algorithm is hybridized with each network to tune its hyperparameters, as they highly affect the segmentation performance. Secondly, a hybrid algorithm of the LeNet-5 model and ABC algorithm, namely, LeNet-5/ABC, is proposed as feature extractor and classifier of liver lesions. The LeNet-5/ABC algorithm uses the ABC to select the optimal topology for constructing the LeNet-5 network, as network structure affects learning time and classification accuracy. For assessing performance of the two proposed algorithms, comparisons have been made to the state-of-the-art algorithms on liver lesion segmentation and classification. The results reveal that the SegNet-UNet-ABC is superior to other compared algorithms regarding Jaccard index, Dice index, correlation coefficient, and convergence time. Moreover, the LeNet-5/ABC algorithm outperforms other algorithms regarding specificity, F1-score, accuracy, and computational time.

scholarly journals Effect of Radiofrequency Ablation with Interventional Therapy of Hepatic Artery on the Recurrence of Primary Liver Cancer and the Analysis of Influencing Factors

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Sishuo Zhang ◽  
Ge Zhao ◽  
Honglin Dong
Keyword(s):  
Radiofrequency Ablation ◽  
Treatment Group ◽  
Liver Cancer ◽  
Hepatic Artery ◽  
Primary Liver Cancer ◽  
Combined Treatment ◽  
Interventional Therapy ◽  
Control Group ◽  
Tumor Diameter ◽  
Significant Difference

Background. The probability of liver cancer recurring in patients after surgery is a serious threat to liver cancer patients. Radiofrequency ablation is widely employed in liver cancer cases. We explored the therapeutic effects and influencing factors of radiofrequency ablation combined with hepatic artery intervention in patients with recurrence of primary liver cancer surgery. Methods. 90 patients with primary liver cancer postoperative recurrence admitted to our hospital from January 2014 to February 2017 were selected as the research objects. The patients were randomly divided into the control group (n = 45) and combined treatment group (n = 45). The combined treatment group received radiofrequency ablation combined with hepatic artery interventional therapy, and the control group received hepatic artery interventional therapy. The short-term efficacy, AFP levels before and after treatment, and long-term survival results of the two groups were compared. Single-factor and multifactor analyses of the clinical information of the combined treatment group were carried out to find out the factors affecting the therapeutic effect of radiofrequency ablation combined with hepatic artery intervention on patients with recurrence of primary liver cancer. Results. The total effective rate of short-term curative effect of the combined treatment group was higher than the control group, and there was a statistically significant difference existing ( P  < 0.05). After treatment, two groups of patients’ AFP levels were greatly lower than before treatment, the AFP levels of the combined treatment group were significantly lower than the control group, and there was a statistically significant difference ( P  < 0.05). The survival rates of patients in the combined treatment group at the sixth month, the first year, and the second year after treatment were significantly higher than those of the control group, and there was a statistically significant difference ( P  < 0.05). The univariate results showed that, in the combined treatment group, there were statistically significant differences between the effective group and the ineffective group in tumor diameter, intact capsule, liver cirrhosis, intrahepatic spread, and tumor adjacent to large blood vessels ( P  < 0.05). The outcomes of multivariate analysis indicated that tumor diameter ≥ 3 cm, incomplete capsule, intrahepatic spread, and tumor adjacent to large blood vessels were risk factors for ineffective recurrence of patients with primary liver cancer after radiofrequency ablation combined with hepatic artery intervention ( P  < 0.05). Discussion. Tumor diameter ≥ 3 cm, incomplete capsule, intrahepatic spread, and tumor adjacent to large blood vessels are risk factors for the ineffectiveness of radiofrequency ablation combined with hepatic artery interventional therapy for patients with recurrence of primary liver cancer. It is necessary to increase the range of radiofrequency treatment, increase the temperature of the radiofrequency needle, and strengthen postoperative follow-up interventions based on the specific conditions of the patient's tumor.

scholarly journals Clinical Observation of Laparoscopic Anatomic Hepatectomy for Early Primary Liver Cancer

2021 ◽  
Vol 233 ◽  
pp. 02026
Author(s):  
Yan Shaoxiong ◽  
Shen Shiheng
Keyword(s):  
Liver Resection ◽  
Liver Cancer ◽  
Clinical Effect ◽  
Liver Tumors ◽  
Primary Liver Cancer ◽  
Rapid Development ◽  
Operation Time ◽  
Clinical Results ◽  
Early Primary ◽  
Malignant Liver

At present, liver resection is the most effective treatment for malignant liver tumors, and with the rapid development of medical technology, anatomical liver resection has been widely used in clinical practice. This paper mainly studies the clinical effect of laparoscopic anatomic hepatectomy in the treatment of early primary liver cancer. According to the surgical method, the patients were divided into anatomic and non-anatomic hepatectomy groups. Preoperative, intraoperative and postoperative efficacy data of the two groups were analyzed. According to the clinical results, the anatomical resection of liver cancer has short operation time, fewer postoperative complications, fast recovery of liver function, and long survival time without tumor, with obvious clinical effect and definite curative effect, which is worthy of promotion.

scholarly journals Feasibility of mesentericoportal vein reconstruction by autologous falciform ligament during pancreaticoduodenectomy—cohort study

BMC Surgery ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yi Shao ◽  
Jiaojiao Feng ◽  
Yuancong Jiang ◽  
Zhenhua Hu ◽  
Jian Wu ◽  
...  
Keyword(s):  
Medical Records ◽  
Patency Rate ◽  
Operation Time ◽  
Postoperative Hospital Stay ◽  
Ductal Adenocarcinoma ◽  
Falciform Ligament ◽  
Common Procedure ◽  
Term Survival ◽  
Significant Difference

Abstract Background Mesentericoportal vein (MPV) resection in pancreatic ductal adenocarcinoma (PDAC) surgery has become a common procedure. A few studies had described the use of falciform ligament (FL) for MPV reconstruction and received encouraging preliminary effects. Aims This study was designed to explore the feasibility and efficacy of this technique compared with others. Methods Patients who underwent pancreaticoduodenectomy (PD) with MPV resection for PDAC from 2009 to 2018 were enrolled. Medical records were retrospectively reviewed, MPV reconstructions using FL were distinguished and compared with other techniques. Results 146 patients underwent MPV reconstruction, and 13 received FL venoplasty. Other reconstruction techniques included primary end-to-end anastomosis (primary, n = 30), lateral venorrhaphy (LV, n = 19), polytetrafluoroethylene conduit interposition (PTFE, n = 24), iliac artery (IA) allografts interposition (n = 47), and portal vein (PV) allografts interposition (n = 13). FL group holds the advantages of shortest operation time (p = 0.023), lowest blood loss (p = 0.109), and shortest postoperative hospital stay (p = 0.125). The grouped patency rates of FL, primary, LV, PTFE, IA, and PV were 100%, 90%, 68%, 54%, 68%, and 85% respectively. Comparison displayed that FL had the highest patency rate (p = 0.008) and lowest antiplatelet/anticoagulation proportion (p = 0.000). Complications and long-term survival were similar among different techniques. The median survival time of patent group (24.0 months, 95% CI: 22.0–26.0) was much longer than that of the thrombosed (17.0 months, 95% CI: 13.7–20.3), though without significant difference (P = 0.148). Conclusions PD with MPV resection and reconstruction by FL is safe, feasible, and efficacious, it might provide a potential benefit for patients.

scholarly journals Distribution of prostheses position after primary total knee arthroplasty on dominant and non-dominant sides

2020 ◽  
Author(s):  
ZHAO Fengchao ◽  
LIU Lei ◽  
Zha Guochun ◽  
Yang Guanjie ◽  
Xu Shizhuang ◽  
...  
Keyword(s):  
Total Knee Arthroplasty ◽  
Knee Arthroplasty ◽  
Primary Total Knee Arthroplasty ◽  
Operation Time ◽  
Dominant Group ◽  
Total Operation Time ◽  
Significant Difference ◽  
Total Knee ◽  
The Mean ◽  
Primary Total Knee

Abstract Background To investigate the changes of prosthesis position after primary total knee arthroplasty (TKA) on the dominant and non-dominant sides. Methods A retrospective analysis was made of 132 patients (148 knees) who underwent primary TKA from December 2016 to December 2018 in our hospital. The patients were divided into dominant group (right side) and non-dominant group (left side) according to the position of the three right-handed surgeons. Total operation time, posterior distal femur angle (PDFA), posterior proximal tibia angle (PPTA), malposition rate of femoral prostheses in sagittal, postoperative hip-knee-ankle angle (HKA), mechanical lateral distal femoral angle (mLDFA), mechanical medial proximal tibial angle (mMPTA) were compared between the two groups. Results The mean total operation time was in dominant group was 111.8(111.8±26.9) and in non-dominant group was 113.7(113.7±26.1) (P>0.05). Postoperative sagittal alignment, the mean PDFA was 90.2(90.2°±3.3°) in dominant group and 88.8(88.8°±3.6°) in non-dominant group (P<0.05). The mean PPTA was 84.8(84.8°±2.8°) in dominant group and 85.4(85.4°±3.7°) in non-dominant group (P>0.05). The incidence of malposition of sagittal femoral prosthesis in dominant group was 6/76 (7.9%) and that in non-dominant was 15/72 (20.8%). There was a significant difference between the two groups (χ2=5.083，P=0.024). Postoperative coronal alignment, the mean angle of components placement was 2.1°±4.2° for HKA, 88.7°±2.7° for mLDFA, 89.5°±2.7° for mMPTA in dominant group and 1.6°±4.1° for HKA, 89.0°±2.8° for mLDFA, 89.9°±2.7° for mMPTA in non-dominant group, respectively. There were no significant difference between the two groups (t=0.804 P=0.423, t=-0.564 P= 0.574, t=-1.011 P= 0.314). Conclusion Our study suggests that surgeon handedness is likely to be one of factors that affect the sagittal placement of femoral component. Orthopaedic surgeons should be aware of the potential problems and consider taking extra precautions to mitigate the risk before performing surgery.

scholarly journals Comparison of the Imaging Manifestations and Diagnostic Values of Multi-slice Spiral CT and Enhanced MRI Scans of Primary Liver Cancer (PLC) Intrahepatic Lesions

2020 ◽  
Vol 4 (6) ◽  
Author(s):  
Heng Tang ◽  
Xiang Gao
Keyword(s):  
Liver Cancer ◽  
Diagnostic Accuracy ◽  
Detection Rate ◽  
Primary Liver Cancer ◽  
Spiral Ct ◽  
Diagnostic Value ◽  
Arterial Phase ◽  
Enhanced Mri ◽  
Mri Scans ◽  
The Difference

Objective: To compare and analyze the clinical diagnostic value of multi-slice spiral CT and enhanced MRI for primary liver cancer (PLC), and to summarize the imaging findings.  Methods: The research subjects in this article were 50 patients with PLC who were admitted to our hospital from 2017 April to 2018 September. After the patients were admitted, they were examined by multi-slice spiral CT and enhanced MRI scanning, and the pathological diagnosis results were followed up. Relevant information was reviewed and analyzed.  Results: The detection rate of multi-slice spiral CT was higher than that of MRI in the portal venous phase lesion detection. The difference was statistically significant (P<0.05). The detection rate of lesions in the arterial phase and delayed phase was not statistically significant (P>0.05); the diagnostic accuracy of multi-slice spiral CT was 85.96%, and the diagnostic accuracy of enhanced MRI scanning was 91.11%, which was not statistically significant (P>0.05). MRI scans showed the capsules of primary liver cancer better than CT, but the difference was not statistically significant (P>0.05).  Conclusion: In conclusion, both multi-slice spiral CT and enhanced MRI can be used for the effective diagnosis of primary liver cancer intrahepatic lesions. The diagnostic value of the two is equivalent, but enhanced MRI has a slightly higher diagnostic accuracy and can be used as the preferred method.

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