Asymptomatic Scalp Carriage among Household Contacts of Children Affected by Tinea Capitis: A Prospective Study in the Metropolitan Area of Brussels, Belgium

2021 ◽  
pp. 1-6
Author(s):  
Pauline Lecerf ◽  
Chantal Dangoisse ◽  
Aude Van Ooteghem ◽  
Anja Vujovic ◽  
Laura Vollono ◽  
...  
Keyword(s):  
Metropolitan Area ◽  
Prospective Studies ◽  
Tinea Capitis ◽  
Infectious Agent ◽  
University Hospitals ◽  
Dermatology Department ◽  
Female Ratio ◽  
Household Contacts ◽  
Potential Reservoir ◽  
A Prospective Study

<b><i>Introduction:</i></b> Tinea capitis (TC) is a superficial fungal infection affecting the scalp. The existence of asymptomatic carriers (ACs) could represent a potential reservoir responsible of (re)contamination and failure of treatment. No prospective studies on ACs in household contacts of TC patients in Europe have been published to date. <b><i>Objectives:</i></b> The aim of this study was to assess the prevalence of ACs in a cohort of household contacts of children who were diagnosed with TC in the metropolitan area of Bruxelles, Belgium. <b><i>Methods:</i></b> This prospective observational study was conducted from October 2015 to April 2016 at the Dermatology Department of the University Hospitals Brugmann, Saint-Pierre, Queen Fabiola Children Hospital. <b><i>Results:</i></b> Ninety-nine cases of TC from 95 different family circles were included. The main infectious agent identified was <i>Microsporum audouinii</i> in 53 cases. The mean age of TC patients was 5.8 years. Male/female ratio was 2.8. Eighty-one household contacts of TC patients were enrolled in the study. Two cases of ACs (5%) were identified. <b><i>Conclusions:</i></b> <i>M. audouinii</i> was the most common pathogen identified. The prevalence of ACs we report is on average higher compared to other European large cities. Larger prospective studies including all close contacts of affected patients are required in order to establish guidelines regarding identification and management of ACs.

Sociodemographic, Clinical Profile and Outcome of Tuberculosis in Baramulla District of North Kashmir of India

JMS SKIMS ◽  
2018 ◽  
Vol 21 (1) ◽  
pp. 11-16
Author(s):  
Abdul Ahad Wani ◽  
Javeed Iqbal Bhat ◽  
Muzafar Naik ◽  
Nisar Ahmed Dar ◽  
Syed Masood Ahmed
Keyword(s):  
Elementary Education ◽  
Pulmonary Tuberculosis ◽  
Rural Areas ◽  
Extrapulmonary Tuberculosis ◽  
Steady Increase ◽  
Female Ratio ◽  
Directly Observed Treatment ◽  
Night Sweats ◽  
Immunodeficiency Syndrome ◽  
A Prospective Study

Background: India accounts for one-fourth of the global tuberculosis (TB) burden. Since the countrywide implementation of RNTCP, tuberculosis care has received renewed focus. Directly observed treatment short-term (DOTS) is a cornerstone of RNTCP program. Objective: To evaluate demographic profile, clinical presentation and outcome of TB in district Baramulla of North Kashmir. Methods:  A prospective study over a period of seven years in patients diagnosed with TB in district Baramulla of North Kashmir. Results: This study was conducted prospectively over seven years from March 2011 to February 2017. A total of 802 patients were enrolled in the study. Among them, there were a total of 638 adult patients and 164 paediatric patients with a male: female ratio of 1:0.99. Majority of patients belonged to rural areas of north Kashmir and had received no or elementary education. Pulmonary tuberculosis was diagnosed in 530 (66 %) patients and 272 (34%) patients were diagnosed as extrapulmonary tuberculosis. Sputum for AFB was important mode of diagnosis in our series and was positive in 525 (65%) our patients. Majority of patients presented with fever, weight loss, and night sweats. None of the patients had Acquired Immunodeficiency syndrome (AIDS). There was a consistent improvement in AFB isolation among TB patients over the study period. Majority of our patients were cured completely of disease Conclusion: Sputum positive pulmonary tuberculosis remains the most common presentation of tuberculosis in North Kashmir. There is a steady increase in the proportion of bacteriologically confirmed TB cases over the study period. Furthermore, DOTS treatment is successful in all forms of tuberculosis. JMS 2018;21(1):11-16

scholarly journals The association of bullous pemphigoid with dipeptidyl-peptidase 4 inhibitors: a ten-year prospective observational study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Vaia Lambadiari ◽  
Aikaterini Kountouri ◽  
Foteini Kousathana ◽  
Emmanouil Korakas ◽  
Georgios Kokkalis ◽  
...  
Keyword(s):  
Bullous Pemphigoid ◽  
Prospective Observational Study ◽  
Dipeptidyl Peptidase ◽  
Dermatology Department ◽  
Steroid Administration ◽  
Dipeptidyl Peptidase 4 ◽  
Increased Risk ◽  
Dipeptidyl Peptidase 4 Inhibitors ◽  
A Prospective Study

Abstract Background Bullous pemphigoid is the most common bullous chronic autoimmune skin disease. Recent studies have suggested dipeptidyl-peptidase 4 inhibitors as possible predisposing agents of bullous pemphigoid. The objective of our study was to prospectively estimate the association between gliptins and the development of bullous pemphigoid. Methods We conducted a prospective study which included all patients diagnosed with biopsy-proven bullous pemphigoid in the Dermatology Department of our hospital between April 1, 2009 and December 31,2019. The diagnosis of bullous pemphigoid was based on specific clinical, histological and immunological features. Results Overall 113 consecutive patients (age 75 ± 13 years, 62 females) with the diagnosis of bullous pemphigoid were enrolled. Seventy-six patients (67.3%) suffered from type 2 Diabetes and 52 (46%) were treated with dipeptidyl-peptidase 4 inhibitors. The most frequent prescribed gliptin was vildagliptin, being administered to 45 cases (39.8% of total patients enrolled, 86.5% of the patients treated with gliptins). Gliptins were withdrawn immediately after the diagnosis of bullous pemphigoid, which together with steroid administration led to remission of the rash. Conclusions This study revealed that treatment with dipeptidyl-peptidase 4 inhibitors, especially vildagliptin, is significantly associated with an increased risk of bullous pemphigoid development.

scholarly journals Cost analysis of facial injury treatment in two university hospitals in Malaysia: a prospective study

2017 ◽  
Vol Volume 9 ◽  
pp. 107-113 ◽  
Author(s):  
Saperi Bin Sulong ◽  
Roszalina Ramli ◽  
Zafar Ahmed ◽  
Amrizal Muhd Nur ◽  
Muhammad ismail Ibrahim ◽  
...  
Keyword(s):  
Cost Analysis ◽  
Prospective Study ◽  
Facial Injury ◽  
University Hospitals ◽  
Injury Treatment ◽  
A Prospective Study

scholarly journals Halitosis: Its Aetiology and Psychosocial Impact- A Hospital Based Study

2021 ◽  
Vol 29 (2) ◽  
pp. 145-150
Author(s):  
Gopika Kalsotra ◽  
Monica Manhas ◽  
Sachin Gupta ◽  
Heemani Bhardwaj ◽  
Parmod Kalsotra ◽  
...  
Keyword(s):  
Social Life ◽  
Laryngopharyngeal Reflux ◽  
Systemic Disease ◽  
Tertiary Care ◽  
Neck Surgery ◽  
Psychosocial Impact ◽  
Care Hospital ◽  
Female Ratio ◽  
Study Results ◽  
A Prospective Study

Introduction Halitosis means bad or unpleasant odour from oral cavity. It causes embarrassment to the patients and affects their social life and communication. This study aims to find the causes of halitosis and to assess its psychosocial impact. Materials and Methods A prospective study was conducted in the department of Otorhinolaryngology and Head Neck Surgery in a tertiary care hospital. It included 165 patients, presenting to the ENT OPD with chief complains of oral malodour for at least 3 months. The patients in the age above 15 years and below 75 years, irrespective of gender, were included in the study. Results The age of the patients ranged from 15 to 75 years with a mean age of 52.24 ± 15.67 with male: female ratio of 7:10. The most common cause of halitosis in the present study included chronic rhinosinusitis (38.7%), gingivitis/periodontitis (19.39%), tonsillitis (4.84%), laryngopharyngeal reflux (2%), deep neck space infections (1.2%). In 23.56%, the halitosis was a symptom of an underlying malignancy. Conclusion Halitosis from an extra oral origin can be the sign of an underlying systemic disease or malignancy. The consultation should be done with the periodontist, ENT specialist and a physician.

scholarly journals Incidence of Iatrogenic Lumbar Spinal Instability after Laminectomy, Discectomy or Facetectomy

2021 ◽  
Vol 9 (B) ◽  
pp. 588-592
Author(s):  
Ahmed A. Hafez ◽  
Ahmed Hamdy Ashry ◽  
Ahmed Elsayed ◽  
Amr El Tayeb ◽  
Mohamed Badran Abdel Salam ElShenawy
Keyword(s):  
Back Pain ◽  
Lumbar Spine ◽  
Prospective Study ◽  
Lumbar Spine Surgery ◽  
Spinal Instability ◽  
Lumbar Stenosis ◽  
University Hospitals ◽  
Lumbar Spinal ◽  
A Prospective Study ◽  
Postoperative Instability

OBJECTIVE: This thesis aim to report the incidence of iatrogenic spinal instability that occurs after laminectomy, discectomy or facetectomy in Lumbar spine surgery. METHODS: This is a prospective study of 50 cases of degenerative lumbar spondylosis complaining of various symptoms of claudication, sciatica and back pain which were surgically managed by laminectomy according to the level of stenosis in the period between October 2018 and October 2020 in the neurosurgery department at Cairo university hospitals. Mesial facetectomy was added according to the degree of stenosis if needed. Some patients needed discectomy if sciatica was an eminent symptom. RESULTS: Out of 50 patients included: 9 patients (18%) developed postoperative instability. The number of levels operated on and the degree of mesial facetectomy were found to be variables that may affect postoperative stability. CONCLUSION: Iatrogenic instability may result from large laminectomy and extensive facetectomy for lumbar stenosis in patients who do not have obvious pre-existing instability. Key words: Iatrogenic spinal instability - Laminectomy - conventional open discectomy - Mesial facetectomy.

scholarly journals Comparison of efficacy of myringoplasty in dry and wet ears in chronic otitis media of tubotympanic type

2017 ◽  
Vol 3 (3) ◽  
pp. 705 ◽  
Author(s):  
Yogeshwar Chandrashekar ◽  
Ravishankar Chandrashekar
Keyword(s):  
Otitis Media ◽  
Statistical Significance ◽  
Chronic Otitis Media ◽  
Pure Tone Audiometry ◽  
Inflammatory Cells ◽  
P Value ◽  
Hearing Improvement ◽  
Female Ratio ◽  
Fascia Graft ◽  
A Prospective Study

<p class="abstract"><strong>Background:</strong> The objective of the study was to compare the outcome of myringoplasty in dry and wet ears in tubotympanic type of chronic otitis media (COM) with respect to graft uptake and hearing improvement.</p><p class="abstract"><strong>Methods:</strong> This is a prospective study done in department of ENT Bangalore Medical College and Research Institute during the study period of November 2014 to May 2016, wherein a total of 60 patients of tubotympanic type COM with 30 cases each of dry and wet ears, aged 15-60 years were included. The hearing impairment was assessed and recorded by pure tone audiometry (PTA). After obtaining informed written consent the patients underwent myringoplasty (temporalis fascia graft, underlay technique). Microbiological examination of discharge in wet ears was done and histopathology of the excised remnant TM analyzed in both groups. Both groups of patients were followed up for 3 months and assessed for graft uptake and hearing improvement. PTA was repeated at 3 months postoperatively.  </p><p class="abstract"><strong>Results:</strong> Our study included 60 patients of tubotympanic type of COM with 30 cases each with dry and wet ears who underwent myringoplasty. Majority of our patients were in second decade in both the groups. There was slight female preponderance in our study with male to female ratio of 0.93:1. Discharge from ears in wet ears was mucoid in consistency and were culture negative. Histopathology of excised remnant TM in wet ears revealed evidence of inflammatory cells and vascularization within stroma of fibroblasts while these were absent in dry ear cases. The overall successful graft uptake following myringoplasty was 88.3% with 86.7% for wet ears and 90% for dry ears with no statistical significance (p value of 0.688&gt;0.05) between the two groups. With respect to hearing improvement post-operatively there was significant hearing improvement in both the groups when compared to preoperative hearing with a mean hearing gain (dB) of 3.43±2.81 in wet ear cases to 3.85±3.05 in dry ear cases, but when compared between the two groups, there was no significant statistical difference (p value of 0.582&gt;0.05).</p><p><strong>Conclusions:</strong> The outcome is equally good for myringoplasty in dry and wet ears in tubotympanic type of chronic otitis media with respect to graft uptake and hearing improvement. </p>

Clinical Manifestations of Cholelithiasis in Quito, Ecuador. A Cohort Study

2021 ◽  
pp. 12
Author(s):  
◽  
◽  
Keyword(s):  
Epigastric Pain ◽  
Medical Center ◽  
Clinical Manifestations ◽  
Abdominal Ultrasound ◽  
Common Symptom ◽  
Low Back ◽  
Female Ratio ◽  
Male Female Ratio ◽  
The Right ◽  
A Prospective Study

Introduction: A prospective study was carried out, with the aim of establishing the clinical manifestations of cholelithiasis in the population of Quito, Ecuador. Methods: During the period from January 2012 to October 2017, 534 patients were referred from different outpatient clinics of the Ecuadorian Institute of Social Security to the Batan Medical Center with the diagnosis of cholelithiasis after a clinical assessment and abdominal ultrasound, to be treated surgically. Results: Sixty-nine percent of patients were female with a male-female ratio of 1:2.21. Mean age was 44.9 years. Pain was the most common symptom in our study: 95.7%. Among these patients, pain was located in the epigastrium in 49.8%, in the right hypochondrium in 45.1% and only 0.8% had low back pain. Pain ranged from moderate and even severe. The remaining 4.3% of patients had dyspepsia or were asymptomatic. Conclusions: This finding highlights the fact that epigastric pain must be always considered as a clinical manifestation on cholelithiasis.

scholarly journals Pattern of Sexually Transmitted Diseases (STDs) Among Patients Attending Out Patient Department of Dermatology of Dhaka Medical College Hospital, Dhaka, Bangladesh

1970 ◽  
Vol 19 (1) ◽  
pp. 7-10
Author(s):  
CM Ali ◽  
TK Sikdar ◽  
N Sultana ◽  
N Ahmed ◽  
AKMR Haque ◽  
...  
Keyword(s):  
Sexually Transmitted Diseases ◽  
Secondary Level ◽  
Educational Status ◽  
Medical College Hospital ◽  
College Hospital ◽  
Dermatology Department ◽  
Female Ratio ◽  
Male And Female ◽  
Sexually Transmitted ◽  
Medical College

The study was conducted among 568 patients of STDs out of 58560 male and female patients in the OPD of Dermatology Department of Dhaka Medical College Hospital (DMCH) during the period of March 2009 to February 2010 irrespective of sex and age >15 years with a view to assess the prevalence of sexually transmitted diseases. In this study prevalence of STDs such as gonorrhea, syphilis, non gonococcal urethritis, chancroid, genital herpes and genital warts were 29.58%, 12.68%, 41.58%,4.93%,8.45% and 2.82% respectively; male and female ratio were 3.73:1. The highest prevalence rate was found in age group of 25-34 years (42.25%). According to educational status of the respondents, 33.80% were up to secondary level and only 2.82% were master degree holder. Among occupation 36.62% were in service, and 15.49% were students. According to socioeconomic status 40.14% were poor and only 9.86% were from upper middle class. Key words: Sexually transmitted diseases; prevalence. DOI: 10.3329/jdmc.v19i1.6243 J Dhaka Med. Coll. 2010; 19(1) : 7-10.

scholarly journals Conventional Photodynamic Therapy versus Fractional CO2 Laser Assisted Photodynamic Therapy in Treatment of Onychomycosis

QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
M M A Abdallah ◽  
M T Mahmoud ◽  
M Y Soltan ◽  
M M M Abughali
Keyword(s):  
Photodynamic Therapy ◽  
Clinical Signs ◽  
Diagnostic Techniques ◽  
Aspergillus Species ◽  
Controlled Study ◽  
Fungal Culture ◽  
Mycological Cure ◽  
University Hospitals ◽  
Humid Climate ◽  
Dermatology Department

Abstract Background Onychomycosis is a common persistent infection of the nail unit by fungi either dermatophytes, yeasts or non-dermatophyte molds (NDMs). It is classified clinically to distal and lateral subungual onychomycosis (DLSO), superficial white onychomycosis (SWO), proximal subungual onychomycosis (PSO), candidal onychomycosis, endonyx onychomycosis and total dystrophic onychomycosis (TDO). Onychomycosis is commonly confirmed by clinical examination side by side with regular diagnostic techniques such as direct microscopy and fungal culture, which are considered the golden are considered the golden standards of diagnosis. Aim of the Work to evaluate two PDT approaches in the treatment of onychomycosis. The study will compare the effect of PDT using conventional method versus fractional CO2 assisted PDT for achievement of a clinical and mycological cure in cases of onychomycosis. Patients and Methods we conducted a right-left controlled study, on 21 patients with at least 2 toenails onychomycosis in the same patient. These patients were recruited from outpatient clinic of dermatology department at Ain Shams University Hospitals. The study was conducted during the period from December 2016 till June 2017. Twenty-one patients (4 males and 17 females) with clinical signs of toenail onychomycosis were enrolled in the study. The diagnosis was confirmed via laboratory studies. Results in our study, we found that Aspergillus species were the most common causative organisms of OM followed by and this is possibly because the non NDMs are more frequent in tropical and subtropical areas with a hot and humid climate. Conventional PDT and fractional CO2-assisted PDT have an antifungal activity as manifest by a mycological cure rate of 57.1% and 76.2% in OM cases respectively. Fractional CO2-assisted PDT was superior to conventional PDT as regard the clinical improvement in nail appearance and patient satisfaction. Conclusion non-dermatophyte molds are important and common pathogens in toenail onychomycosis. Aspergillus species play an important role as pathogens for toenail onychomycosis in Egypt.

scholarly journals Dietary lifestyle modifications for vitiligo patients

2019 ◽  
Vol 10 (4) ◽  
pp. 45
Author(s):  
Sahar A. Abd-El Mohsen ◽  
Azhar A. Mohamed
Keyword(s):  
Research Design ◽  
Rural Areas ◽  
P Value ◽  
University Hospitals ◽  
Lifestyle Modifications ◽  
Dermatology Department ◽  
Patient Interview ◽  
Significant Difference ◽  
Post Test ◽  
Quasi Experimental

Background and objective: Changing the patient lifestyle as regarding diet well helped in vitiligo patient cure. Aim: to examine the effect of applying dietary instructions on dietary lifestyle modifications of vitiligo patients.Methods: Research design: Quasi experimental research design with one group (Pre/Post-test) was utilized in this study. Setting: the study was conducted in the ultraviolet unit at the Dermatology Department of Asyut University Hospitals. Study tool: Structured patient interview questionnaire sheet. It included two parts: Part 1: Assessment of patient’s sociodemographic variables. Part 2: Dietary pattern assessment: derived from Patient Life Style Pattern Assessment Sheet (PLSPAS) for Vitiligo.Results: The mean age of the studied sample was (mean ± SD 34.62 ± 12.35), 51.6% were female, 70% were living in rural areas, a highly statistically significant difference in the total mean knowledge scores between pre and post application of the dietary instructions (p value = .002).Conclusions: The present study concluded that there was a great improvement in the dietary lifestyle pattern of the studied sample after application of dietary instructions. Recommendations: Replication of the study on a larger probability sample from different geographical locations for generalization of the results. Printing copies of the dietary instructions for dissemination among all vitiligo patients attending the dermatology ward for treatment or follow-ups.

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