Abstract 142: Evaluation of Clinical Efficacy and Safety of a Newly Developed Automated Cardiopulmonary Resuscitation Device; A Porcine Cardiac Arrest Model

Circulation ◽  
2018 ◽  
Vol 138 (Suppl_2) ◽  
Author(s):  
Ki Hong Kim ◽  
Sang Do Shin ◽  
Tae Han Kim ◽  
Ki Jeong Hong ◽  
Seong Wook Choi ◽  
...  

Background: Various automated compression device (ACD) have been adopted by emergency medical services (EMS) worldwide to ensure cardiopulmonary resuscitation (CPR) quality. We developed a new ACD with a manual adjustment function according to compression depth and rate. This study aimed to compare the CPR quality and chest injury caused between the new ACD and a conventional device (LUCAS, Physio-Control, Sweden). Methods: A randomized experimental trial using each eight pigs for ACD and Lucas group were performed to compare the CPR quality, outcomes, and safety. After 1-minute of untreated electrical-induced ventricular fibrillation, followed by 8-minutes of basic life support, and 20-minutes of advanced cardiac life support including epinephrine infusion were provided under mechanical ventilation. Hemodynamic parameters were obtained and observed end-tidal CO2 (ETCO2) were continuously measured from endotracheal tube as study outcome. Mixed model analysis and repeated measure ANOVA were used to compare the difference of hemodynamic parameters and observed ETCO2. We examined the all pigs for gross pathologic findings (number of lung contusion, laceration, bone fracture, and hematoma in the thoracic cavity) after CPR procedures through open thoracotomy. Results: There was no significant difference for hemodynamic parameters such as mean arterial pressure, 29.4 mmHg in ACD group versus 35.3 mmHg in Lucas group (p-value= 0.39). Observed ETCO2 between ACD and Lucas group were 18.0 and 26.8 mmHg (p-value=0.24). Repeated measure ANOVA for observed ETCO2 did not show significant difference (17.6 versus 26.0, p-value= 0.29). The gross pathologic findings through open thoracotomy examination after CPR showed insignificant difference of injury number in chest cavity and wall (7.63 versus 9.38, p-value= 0.49). Conclusions: Hemodynamic parameters and observed ETCO2 were slightly better in Lucas group than new ACD group. However, the statistical significances were not found in the porcine experimental mechanical models.

2018 ◽  
Vol 21 (2) ◽  
pp. 172
Author(s):  
Elham Hasani ◽  
Narges Panahandeh ◽  
Sayna Shamszadeh ◽  
Ahmad Najafi Abrandabadi ◽  
Seyedeh Mahsa Sheikh-Al-Eslamian

<p>Polymer networks are considered to be largely affected by water and chemical absorption from environment. <strong>Objective: </strong>The aim of this study was to evaluate the hygroscopic expansion of bulk-fill composite. <strong>Material and Methods:</strong> Fifteen disks (5 in each group) with different thickness(4mm/2mm) of Tetric N-Ceram Bulk Fill composite(TB) and Tetric N-Ceram composite(TN) were made according to the manufacturer’s instruction and stored in deionized water. The length of each specimen was recorded using a digital micrometer at baseline and at the end of 24 h, 1, 2, 4, 12 weeks intervals. Repeated measure ANOVA and Tukey HSD were used to determine the effect of variables. At 12 weeks, the mean hygroscopic expansion after water immersion ranged between 0. 33±0.09mm for TN to 0.41±0.07mm for TB with 2mm thickness. Repeated measure ANOVA revealed a significant increase in hygroscopic expansion over time (P&lt;0.05). <strong>Results: </strong>The results indicated that at 24hours and 2weeks there was a significant difference among TN and TBwith 4mm thickness (p=0.007 and p=0.023, respectively). The other differences were not significant.<strong> </strong>Hygroscopic expansion affected by the type of composite and the passing of time. <strong>Conclusion: </strong>The results showed that the time taken to reach stabilization in hygroscopic expansion was shorter for TN in comparison with TB. For 2mm thickness equilibrium was attained earlier.</p><p><strong> </strong></p><p><strong>Keywords</strong></p><p>Water; Expansion; Composites; Polymerization; Bulk-fill.</p>


2019 ◽  
Vol 6 (2) ◽  
pp. 135-142
Author(s):  
Azizatul Hamidiyah ◽  
Dewi Andariya Ningsih ◽  
Lia Fitria

Anemia is a health problem that often occurs, especially in developing countries. Young women have a ten times greater risk of anemia compared to young men. Santri has a higher prevalence of anemia than teenage girls in general. One effort that can be done in the treatment of anemia is fortification. Therefore, the purpose of this study was to determine the effect of Moringa Oleifera nugget fortification on increasing hemoglobin levels. This research method used true experimental design. The sample in this study amounted to 30 with simple random sampling technique. The instrument of this study used nutritional observation and recall sheets and the digital HB Check brand Quick Check. The analysis of this study used a univariate and bivariate test with repeated measure anova test. The results showed no effect of Moringa Oleifera nugget fortification on increasing hemoglobin levels with a P value of 0.234> 0.05. Keywords              : Fortification, Moringa Oleifera Nugget, Hemoglobin Levels ABSTRAK   Anemia merupakan masalah kesehatan yang banyak terjadi terutama di negara  berkembang. Remaja putri memiliki risiko anemia sepuluh  kali lebih besar dibandingkan dengan remaja putra. Santri memiliki prevalensi anemia yang lebih tinggi dibanding remaja putri pada umumnya. Salah satu upaya yang dapat dilakukan dalam penangulangan anemia adalah dengan fortifikasi. Oleh karena itu, tujuan penelitian ini adalah untuk mengetahui pengaruh fortifikasi nugget Moringa Oleifera terhadap peningkatan kadar hemoglobin. Metode penelitian ini menggunakan true experimen design.  Sampel dalam penelitian ini berjumlah 30 dengan teknik simple random sampling dengan kriteria inklusi. Instrumen penelitian ini menggunakan lembar observasi dan recall gizi serta set HB Check digital merk Quick Check. Analisis penelitian ini menggunakan uji univariat dan bivariat dengan uji repeated measure anova. Hasil penelitian menunjukkan tidak ada pengaruh fortifikasi nugget Moringa Oleifera terhadap peningkatan kadar hemoglobin dengan Pvalue 0,234 > 0,05. Kata Kunci: Fortifikasi, Nugget Moringa Oleifera, Kadar Hemoglobin 


2019 ◽  
Vol 6 (4) ◽  
pp. 790-805
Author(s):  
Eda Rukiye DÖNBAK

The present study aims at taking an ecological approach to explain general and private types of accommodation organizations’ ecological movements in Turkey. Distribution Statistics for Certified Accommodation Facilities by Their Type issued by the Ministry of Culture and Tourism of Turkey for the period between 1990 and 2015, was used as data source. General and private organization types were classified by using this data and previous studies in literature. In this study repeated measure ANOVA test is used in order to investigate the significant differences between general and private accommodation groups’ upward trends between years of 1990 – 2015. When the data is tested independently based on years it is found that there is significant difference only in the group of private organizations. There was an upward trend in all groups compared to the years whereas this difference was significant only in the group of private organizations. The results can aid organizations strategically implementing their business plans.


2011 ◽  
Vol 20 (3-4) ◽  
pp. 113-130 ◽  
Author(s):  
Colin Utz-Meagher ◽  
John Nulty ◽  
Lisa Holt

Comparative Analysis of Barefoot and Shod Running This study investigated the biomechanical difference between running barefoot and shod before and after a barefoot training program (BTP). Foot angles at contact (FA), contact time (CT), stride length (SL), initial contact force (ICF), and total peak force (TPF) in shod and unshod runners was analyzed. Fourteen collegiate runners attended 12 total sessions over a two week period. Subjects performed a baseline trial, running eight (10-20 meter) repetitions, four barefoot and four shod, at three different stations; running over a force plate, running in front of a SONY DCR-HC52 video camera (30fps) and running in front of a Casio Exilim Pro EX-F1 camera (300fps). A Post-Test (PT) was conducted at the end of the BTP. A repeated measure ANOVA showed significance (p<.05) in the Test factor, BTP; lowering participants FA mean from 18.8deg+/-.9deg to 5.6deg+/-15.1deg, CT mean from .221m+/-.02m to .2m+/-.03m, and TPF mean from 1427.4N+/-312.9N to 1348.2N+/-269.4N. A repeated measure ANOVA showed significance (p<.05) in the Condition factor (shod vs. unshod); lowering participants FA mean from 23.1deg+/-12.6deg to 1.3deg+/-14.4deg, SL mean from .9m+/-.1m to .8m+/-.1m, and ICF mean from 1465.3N+/- 369.6N to 1324.7N+/-379.4N. Running barefoot and following a BTP alters running biomechanics in ways that may decrease running related injuries.


Author(s):  
Juzer Shabbir ◽  
Fazal Qazi ◽  
Waqas Farooqui ◽  
Shahbaz Ahmed ◽  
Tazeen Zehra ◽  
...  

Propolis is a potent anti-microbial and natural anti-inflammatory by-product obtained from the beehive. Studies have demonstrated the superior biocompatibility and anti-microbial properties of propolis as compared to calcium hydroxide. However, its effect on postoperative endodontic pain is unknown. Therefore, this study aimed to investigate the impact of Chinese propolis paste as an intracanal medicament on postoperative endodontic pain intensities compared with calcium hydroxide (control) at different time intervals in necrotic teeth with periapical radiolucency. Eighty patients with single-rooted necrotic teeth with visible periapical radiolucency were recruited and randomly allocated to either the calcium hydroxide or propolis groups. After chemo-mechanical preparation and intracanal medicament insertion, patients were given the VAS (visual analogue scale) to record pain scores. Inter-group data were compared and analyzed using two-way repeated measure ANOVA (Bonferroni test). A p-value of < 0.025 was considered significant. In total, >78% of the patients experienced no or only mild post-operative pain in both the groups at all time intervals, without any significant difference in pain scores between the two groups (p > 0.025). An overall flare-up rate of 14.8% was found. The results suggest that either of these medicaments can be used as an inter-appointment medication for the prevention of postoperative pain in necrotic cases.


Author(s):  
Mehrdad Mesbah Kiaei ◽  
Mahmoud Reza Mohaghegh ◽  
Gholamreza Movaseghi ◽  
Masoud Ghorbanlo

Urinary system stones are the third most common disease of urinary system following urinary infection and prostate pathology. Extracorporeal shockwave lithotripsy (ESWL) is one of the methods used to treat Urolithiasis where shockwaves are transmitted through skin and body organs and crush the stones into small pieces. This is a painful procedure which usually requires analgesics. Each analgesic drug has its own advantages and disadvantages. The present research seeks to study the effectiveness of using diclofenac suppository in order to control pain and reduce need for venous drugs during ESWL procedure. This is a double blind clinical trial. 158 patients resorting to Shahid Hasheminezhad Specialized Center for ESWL were randomly selected to take part in this projects with due consideration of inclusion criteria. The patients were equally divided into the S (diclofenac suppository) and A (placebo) groups. 2 diclofenac suppositories were used in the S group 20 minutes prior to beginning ESWL. Then, ESWL was carried out in supine position using fluoroscopic conduction with standard method. The present research has studied pain scale of patients, operator’s and patient’s satisfaction during the operation and patient’s hemodynamic parameters in three phases prior to, during, and after ESWL. SPSS v.17 was used to study the data and Chi-Square Tests and Repeated Measure ANOVA were used to analyze the results. The level of significance in the present research was set to P-value<0.05.A review of pain scales across both groups showed that using diclofenac suppository has a significant influence in reducing the pain scale and, hence, need for venous drugs (P-value<0.05). No significant difference was observed between the two groups in terms of heart beat and blood pressure changes in various times (P-value>0.05). The results also report different satisfaction levels for patients and operators across the two groups (diclofenac suppository and placebo) (P-value<0.05). Higher satisfaction levels were observed among both patients and operators in the group receiving diclofenac suppository. A general look at the data yields the conclusion that receiving pain killers (diclofenac suppository) before starting ESWL plays a more efficient role in reducing pain scales of patients and enhancing operators’ satisfaction.


Author(s):  
John Hunninghake ◽  
Justin Reis ◽  
Heather Delaney ◽  
Matthew Borgman ◽  
Raquel Trevino ◽  
...  

Purpose: High-quality cardiopulmonary resuscitation (CPR) for in-hospital cardiac arrest (IHCA) is the primary component influencing return of circulation (ROSC) and survival to hospital discharge, but few hospitals regularly track these metrics. Other studies have demonstrated significant improvements in survival after IHCA events following implementation of a dedicated code team training program. Therefore, we developed a unique curriculum for a Code Team Training (CTT) course, and evaluated its post-implementation effect on CPR quality and post-IHCA patient outcomes at our institution. Methods: CPR quality data was prospectively collected for quality improvement purposes once our institution had that capability, with 12-months pre-CTT and 21 months post-CTT. Pre-CTT data shaped the elements of the four-hour CTT course that included didactics, small group sessions, and high-fidelity simulation exercises. A total of 456 multi-professional code team members were trained in 22 courses. Data collection included CPR quality and translational outcomes for events where CPR was performed, except the ED. CodeNet® software was used for CPR quality measures, cardiac rhythm, defibrillation metrics, use of continuous waveform capnography, and pauses in compressions. Target metrics for CPR quality were based on 2015 AHA guidelines. Key translational outcomes measures included event location, ROSC, and survival to hospital discharge. Results: CPR quality was obtained from 140 of 230 (61%) in- and out-of-hospital pulseless adult cardiac arrest events over 33 months (50 [36%] before CTT and 90 [64%] following the first course). There was no significant difference between groups in terms of event location within the hospital nor initial event rhythm. A total of 116,908 chest compressions were evaluated. Median compressions in target rate improved from 32% before CTT to 49% after CTT (p<0.05). When accounting for target rate and depth, the median compressions rate improved to 38% post-CTT compared to 31% pre-CTT (p<0.05). While compression depth had a non-statistically significant decline (90.8% pre-CTT and 83.4% post-CTT), mean rate and median rate-in-target improved from 119.99 +/- 15.6 cpm and 32.4% pre-CTT to 113.7 +/- 16.1 cpm and 48.6% post-CTT (p<0.05). The rate of ROSC improved from 60% (30 of 50) to 78% (70 of 90) after implementation of CTT (p=0.003), excluding IHCA in the ED. Index IHCA survival rate for our institution improved from 26% to 33% before and after CTT [p-value NS], which far surpasses the national average (23.8%). Conclusions: After the initiation of a CTT course that targets key code team member personnel, CPR quality significantly improved, which was associated with an increase in ROSC and a trend towards increased survival for in-hospital cardiac arrest patients.


2020 ◽  
Vol 29 ◽  
Author(s):  
Diana Paula de Souza Rego Pinto Carvalho ◽  
Allyne Fortes Vitor ◽  
Ana Luisa Petersen Cogo ◽  
Greicy Kelly Gouveia Dias Bittencourt ◽  
Viviane Euzébia Pereira Santos ◽  
...  

ABSTRACT Objective: to compare the levels of general critical thinking and the skills or cognitive attributes involved, individually measured during the training of undergraduate nursing students, through a teaching intervention using Concept Maps. Method: an experimental, randomized, double-blind study with before and after design, conducted with 77 undergraduate nursing students. The research subjects were randomized to the control (38) and experiment (39) groups and both participated in a course on Advanced Life Support in Cardiology for a period of five weeks, when the intervention was the construction of four concept maps. Data collection took place through a sociodemographic questionnaire and the California Critical Thinking Skills Test (CCTST) before and after the course and after in order to measure critical thinking. Results: sociodemographic data confirmed that the groups had similar characteristics. After the intervention using the concept maps, the mean pre-and post-test general critical thinking averages were classified as moderate and showed no statistically significant difference. The t-test for paired samples showed a significantly increased Evaluation skill score (p-value of 0.022) in the posttest for the experiment group. Conclusion: the use of the teaching strategy with construction of the concept maps performed well in the promotion of General Critical Thinking and its abilities. Teaching strategies based on constructivist theories should be encouraged as they play a significant role in improving student learning and critical thinking.


2018 ◽  
Vol 29 (1) ◽  
pp. 88-92 ◽  
Author(s):  
Rebeca Pereira de Menezes ◽  
Paula Damasceno Silva ◽  
Pollyana Caldeira Leal ◽  
André Luis Faria-e-Silva

Abstract This study evaluated the effects of tooth bleaching with high-concentration of hydrogen peroxide on alterations of translucency parameter (TP) and color of dentin and enamel. The crown of five human molars was sectioned into four slices parallel to buccal surface. The dentin of external slices containing buccal/ lingual enamel was fully removed with diamond bur; while these slices were used to assess alterations on enamel. Alterations on dentin were assessed into the center of internal slices. The color of specimens was measured over white and black backgrounds using a spectrophotometer (CieL*a*b) at baseline, allowing to calculate the TP by difference between the color measured over each background. Specimens were submitted to three 15-min applications of 35% hydrogen peroxide followed by their storage in water for one-week. Afterwards, the color measurements were repeated at both backgrounds. Color (∆L, ∆a, ∆b and ∆E) and translucency (∆TP) changes were calculated and data individually analyzed by T-test (α = 0.05). Influence of hard tissue and assessment time on each color parameter was also analyzed by 2-way repeated measure ANOVA (α = 0.05). Tooth bleaching resulted in increased lightness for the enamel, whereas no alteration on this parameter occurred for dentin. No difference between the tooth hard tissues was observed regards the other color parameters and ∆E. A slightly reduction on TP was observed only for the enamel. In conclusion, 35% hydrogen peroxide caused similar color and translucency changes on dentin and enamel.


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