Abstract P160: Associations Between Metabolic Syndrome Severity And Race/ethnicity, Socioeconomic, And Lifestyle Factors

Circulation ◽  
2021 ◽  
Vol 143 (Suppl_1) ◽  
Author(s):  
Christopher C Imes ◽  
Jacob Kariuki ◽  
Eileen Chasens ◽  
Paul Scott ◽  
Kyeongra Yang
Keyword(s):  
Physical Activity ◽  
Metabolic Syndrome ◽  
Severity Score ◽  
Lifestyle Factors ◽  
Education Level ◽  
Poverty Level ◽  
Increased Risk ◽  
Severity Scores ◽  
Weighted Data ◽  
Race Ethnicity

Introduction/Purpose: Metabolic syndrome (MetS) is a disorder characterized by a cluster of cardiometabolic conditions that increase the risk of cardiovascular disease and diabetes. While MetS is treatable through lifestyle changes and medication, factors of race/ethnicity, socioeconomic, and lifestyle may influence MetS severity. Methods: The National Health and Nutrition Examination Survey (NHANES) 2015-2016 dataset was used for this secondary data analysis. Weighted data from individuals aged ≥ 20, not pregnant during the time of the assessment, with self-reported Non-Hispanic (NH) white, NH black, or Hispanic race/ethnicity, and with the variables needed to calculate MetS severity were included in the analysis (N=1850). Severity of MetS was determined using the formula developed by Gurika and DeBoer (2014) and expressed as a Z-score adjusted for sex and race. The severity score includes systolic blood pressure, triglycerides, HDL cholesterol, glucose, and body mass index. Socioeconomic variables included education level and the ratio between annual household income and poverty level. Lifestyle factors included sleep duration, dietary quality, sedentary time, and meeting the physical activity (PA) recommendation of 500 MET-mins/week (yes/no). Z-scores were converted to percentiles, which were categorized into quartiles. Regression analysis was used to examine the associations between MetS severity and race/ethnicity, socioeconomic, and lifestyle factors. Results: Based on weighted data, prevalence of MetS severity >75 th percentile differed across age (20% for 20-40 y/o, 36.4% for 41-60 y/o, 33.0% for 61-80 y/o) and across racial/ethnic (29.4% for NH white, 29.1% for NH black, and 34.9% for Hispanic) groups. Mean MetS severity scores were significantly different between the age and race/ethnicity groups (p <. 001 and p = .014, respectively). While MetS severity scores were not significantly different among the four income to poverty-index ratio groups, the difference between the lowest (≤ 133%) and highest (≥ 500%) group was significantly different (p = .02). In the regression model, a higher quality diet (p <.001), meeting the PA recommendations (p = .008), and higher education level (p = .027) were associated with lower mean MetS severity score. After adjusting for socioeconomic and lifestyle factors, being in the Hispanic race/ethnicity group was associated with higher MetS severity scores (p = .020) compare to being in the NH white group. Conclusions: Diet, physical activity, and educational level were associated with MetS severity score. After adjusting for socioeconomic and lifestyle factors, being in the Hispanic group was associated with the highest MetS severity scores. Research and preventive efforts should focus on groups at increased risk for MetS and severity. Culturally appropriate education and interventions are needed to address this health inequity.

scholarly journals Leisure-Time Physical Activity, Sedentary Behaviour and Diet Quality are Associated with Metabolic Syndrome Severity: The PREDIMED-Plus Study

Nutrients ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 1013 ◽  
Author(s):  
Laura Gallardo-Alfaro ◽  
Maria del Mar Bibiloni ◽  
Catalina M. Mascaró ◽  
Sofía Montemayor ◽  
Miguel Ruiz-Canela ◽  
...  
Keyword(s):  
Physical Activity ◽  
Metabolic Syndrome ◽  
Diet Quality ◽  
Dietary Pattern ◽  
Severity Score ◽  
Leisure Time ◽  
Leisure Time Physical Activity ◽  
Lifestyle Factors ◽  
Depression Symptoms ◽  
Depression Risk

Healthy lifestyle factors, such as physical activity (PA) and Mediterranean diet (MD), decrease the likelihood of developing metabolic syndrome (MetS). The aim of this study was to report main lifestyle components and related factors according to the MetS severity. Cross-sectional analysis was done of baseline lifestyle factors from 5739 participants with overweight/obesity and MetS features (aged 55–75 years) included in the PREDIMED-PLUS primary cardiovascular prevention randomized trial. Participants were categorized in tertiles according to a validated MetS severity score (MetSSS). Anthropometrics, visceral adiposity index, dietary nutrient intake, biochemical marker levels, as well as a Dietary Inflammatory Index and depression symptoms (Beck Depression Inventory-II) were measured. Diet quality was assessed using a 17-item energy-restricted MD questionnaire. Duration and intensity of PA was self-reported using the Minnesota-REGICOR Short Physical Activity Questionnaire. Sedentary behaviours were measured using the Spanish version of the Nurses’ Health Study questionnaire. The 30 s chair stand test was also assessed. Participants with highest MetSSS showed higher values of cardiovascular risk factors (except for total cholesterol and LDL cholesterol), depression risk, sedentary and TV viewing time, and lower moderate and vigorous leisure-time physical activity (LTPA). Highest MetSSS participants tended to a pro-inflammatory dietary pattern and tended to lower MD adherence. In addition, they showed lower carbohydrate and nut intake and higher intake of protein, saturated and trans fatty acids, cholesterol, iodine, sodium, red and processed meat products, other oils different from olive oil and spirit alcoholic drinks. The highest MetS severity score was associated with lower moderate and vigorous LTPA and higher sedentary time and depression risk, as they tended to a pro-inflammatory dietary pattern and lower MD adherence.

scholarly journals A Scoping Review of Modifiable Risk Factors in Pediatric Onset Multiple Sclerosis: Building for the Future

Children ◽  
2018 ◽  
Vol 5 (11) ◽  
pp. 146 ◽  
Author(s):  
Julie Pétrin ◽  
Max Fiander ◽  
Prenitha Doss ◽  
E. Yeh
Keyword(s):  
Physical Activity ◽  
Multiple Sclerosis ◽  
Vitamin D ◽  
Relapse Rate ◽  
Scoping Review ◽  
Full Text ◽  
Lifestyle Factors ◽  
Increased Risk ◽  
Modifiable Lifestyle Factors ◽  
Pediatric Onset

Knowledge of the effect of modifiable lifestyle factors in the pediatric multiple sclerosis (MS) population is limited. We therefore conducted a scoping review, following the framework provided by Arksey and O’Malley. Four databases were searched for pediatric MS and modifiable lifestyle factors using index terms and keywords, from inception to May 2018. All quantitative and qualitative primary articles were included and limited to English and full text. Of the 7202 articles identified and screened, 25 full-text articles were relevant to our objective and were included. These articles focused on diet obesity, physical activity, and sleep. In cross-sectional analyses, these lifestyle factors were associated with increased risk of pediatric onset MS (POMS), and increased disease activity. Diet, particularly vitamin D and vegetable intake, was associated with reduced relapse rate. Obesity was linked to increased risk of POMS, and physical activity was associated with reduced relapse rate and sleep/rest fatigue. Thus, available studies of lifestyle related outcomes in pediatric MS suggest specific lifestyle related factors, including obesity, higher vitamin D levels, and higher physical activity may associate with lower disease burden in POMS. Studies reviewed are limited by their observational designs. Future studies with longitudinal and experimental designs may further clarify the role of modifiable lifestyle factors in this population.

scholarly journals Expanded CURB-65: a new score system predicts severity of community-acquired pneumonia with superior efficiency

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Jin-liang Liu ◽  
Feng Xu ◽  
Hui Zhou ◽  
Xue-jie Wu ◽  
Ling-xian Shi ◽  
...  
Keyword(s):  
Severity Score ◽  
Community Acquired Pneumonia ◽  
Score System ◽  
Pneumonia Severity ◽  
Increased Risk ◽  
Severity Scores ◽  
Low Blood Pressure ◽  
Health Care Associated Pneumonia ◽  
Score Systems ◽  
Better Than

Abstract Aim of this study was to develop a new simpler and more effective severity score for community-acquired pneumonia (CAP) patients. A total of 1640 consecutive hospitalized CAP patients in Second Affiliated Hospital of Zhejiang University were included. The effectiveness of different pneumonia severity scores to predict mortality was compared, and the performance of the new score was validated on an external cohort of 1164 patients with pneumonia admitted to a teaching hospital in Italy. Using age ≥ 65 years, LDH > 230 u/L, albumin < 3.5 g/dL, platelet count < 100 × 109/L, confusion, urea > 7 mmol/L, respiratory rate ≥ 30/min, low blood pressure, we assembled a new severity score named as expanded-CURB-65. The 30-day mortality and length of stay were increased along with increased risk score. The AUCs in the prediction of 30-day mortality in the main cohort were 0.826 (95% CI, 0.807–0.844), 0.801 (95% CI, 0.781–0.820), 0.756 (95% CI, 0.735–0.777), 0.793 (95% CI, 0.773–0.813) and 0.759 (95% CI, 0.737–0.779) for the expanded-CURB-65, PSI, CURB-65, SMART-COP and A-DROP, respectively. The performance of this bedside score was confirmed in CAP patients of the validation cohort although calibration was not successful in patients with health care-associated pneumonia (HCAP). The expanded CURB-65 is objective, simpler and more accurate scoring system for evaluation of CAP severity, and the predictive efficiency was better than other score systems.

scholarly journals Prevalence of Metabolic Syndrome (MetS) and Determinants Among Obese Teachers in Makassar, Indonesia

2020 ◽  
Vol 18 (2) ◽  
Author(s):  
Nurzakiah Hasan MKM ◽  
Veni Hadju ◽  
Nurhaedar Jafar ◽  
Ridwan M. Thaha
Keyword(s):  
Physical Activity ◽  
Metabolic Syndrome ◽  
Heart Diseases ◽  
Cross Sectional Study ◽  
Sitting Time ◽  
Moderate Physical Activity ◽  
Cross Sectional ◽  
Family History Of Diabetes ◽  
Increased Risk ◽  
Study Population

Metabolic Syndrome (MetS) is related to the increased risk of non-communicable diseases (NCDs). Teacher profession is an adult group with various risks of NCDs. This study aims to assess the determinants of the MetS in teachers with central obesity. Material and Methods: The study was conducted in Makassar, South Sulawesi, Indonesia with cross- sectional study design on 12 secondary schools. The number of samples in this study was 129 teachers. The prevalence of the MetS was determined using criteria from the Joint Interim Statement, while physical activity and sitting time were measured using the International Physical Activity Questionnaire (IPAQ). Results: Respondents in our study were mostly women (78.3%) with an average age of 49.8 years. The prevalence of the MetS in our study population was 39.5%. The prevalence of the Mets was higher in Buginese ethnic (70.6%), respondents with more income (56.9%), bachelor degree (80.4%), married (98%), family history of diabetes mellitus, obesity, hypertension and heart diseases (52.9%), and moderate physical activity (37.3%). There was a significant relationship between sitting time 4 hours; p=0.004), parameters of Mets (p<0.001), LDL (p=0.026), and LDL/HDL ratio (p<0.001) with the Mets. Conclusions: The prevalence of the Mets is high among obese teachers in our study population. Sitting time was an important determinant for MetS among obese teachers.

scholarly journals Vitamin D Status and Components of Metabolic Syndrome in Older Subjects from Northern Finland (Latitude 65°North)

Nutrients ◽  
2019 ◽  
Vol 11 (6) ◽  
pp. 1229 ◽  
Author(s):  
Shivaprakash Jagalur Mutt ◽  
Jari Jokelainen ◽  
Sylvain Sebert ◽  
Juha Auvinen ◽  
Marjo-Riitta Järvelin ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Vitamin D ◽  
Dietary Habits ◽  
Lifestyle Factors ◽  
Vitamin D Status ◽  
Endocrine Society ◽  
Northern Latitudes ◽  
Increased Risk ◽  
Vitamin D Levels ◽  
Older Subjects

Introduction: Vitamin D deficiency has been linked to the increased risk of several chronic diseases, especially in people living in the Northern Latitudes. The aim of this study was to assess the vitamin D status in older subjects born in 1945 in Northern Finland (latitude 65°North), and to examine its associations to components of metabolic syndrome (MetS). Methods: In this cross-sectional study, we invited 904 subjects born in 1945 from the Oulu region (Oulu45 cohort), out of an original cohort of 1332 subjects. In the cohort, plasma 25 hydroxyvitamin D (25OHD) levels were determined by an enzyme immunoassay of 263 men and 373 women, with a mean age baseline of 69±0.5 years old. We assessed the participants’ usage of vitamin D supplements, as well as their lifestyle factors, using a questionnaire. Results: Nearly 80% of the subjects had low vitamin D levels [either vitamin D deficient (<50 nmol/L) or insufficient (50 – 75 nmol/L)], and only 20% of the participants had sufficient vitamin D levels (>75 nmol/L) (based on the American Endocrine Society guidelines). The low vitamin D status was associated with a high prevalence of MetS; a significantly higher number of subjects with MetS (41%) had low vitamin D levels in comparison to the non-MetS subjects (38%) (p ≤ 0.05). The subjects under vitamin D supplementation had a significantly lower incidence of MetS (42.6% vs 57.4%) and its components in comparison to the non-supplemented subjects (p ≤ 0.05). Conclusions: Low vitamin D levels are a risk factor for MetS amongst other lifestyle factors, such as dietary habits and physical inactivity, among older subjects in the Northern Latitudes (65°North). Optimal supplementation of vitamin D, along with rich dietary sources of vitamin D, are highly recommended for older subjects as a means to positively affect, e.g., hypertension, insulin resistance, and obesity, as components of the MetS.

scholarly journals An Application of Metabolic Syndrome Severity Scores in the Lifestyle Risk Assessment of Taiwanese Adults

2020 ◽  
Vol 17 (10) ◽  
pp. 3348 ◽  
Author(s):  
Chih-Ming Lin
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Severity Score ◽  
Density Lipoprotein ◽  
Scoring Systems ◽  
Lifestyle Habits ◽  
Gender And Age ◽  
Severity Scores ◽  
Potential Risk Factors ◽  
Lifestyle Risk

A metabolic syndrome (MS) diagnosis was made when the criteria for three or more of five MS components were met. Due to some limitations in the traditional MS criteria, however, different health care societies have sought to develop applicable MS scoring systems instead. Continuous MS scores can be of meaningful value in the prevention, diagnosis, and treatment of MS at different life stages. Relatedly, this study used a database for 27,748 subjects aged 20 to 64 years who received health checks at a health screening institution in Taiwan from 2010 to 2015 to a similar end. Five components of MS (waist circumference, fasting plasma glucose, blood pressure, fasting triglycerides, and high-density lipoprotein) were used to formulate an MS severity score in different gender and age stratums, which was then used to evaluate the risks of various lifestyle habits. Those estimates were then compared with the results for traditional MS diagnosis. The MS severity scores for some behaviors relating to smoking, drinking, physical activity, and sweetened beverage consumption were found to have changed from 0.03 to 0.2; however, a logistic regression analysis with dichotomous diagnosis did not indicate significant links between these behaviors and MS. The models established by the MS severity scores can identify the risk factors for MS in a more sensitive manner than the traditional MS diagnosis can, especially with respect to specific lifestyle habits. MS severity score can serve as an indicator to explore the potential risk factors for subclinical conditions in the early stages of MS.

scholarly journals Relationship Between Metabolic Syndrome and Moderate-to-Vigorous Physical Activity in Youth

2015 ◽  
Vol 12 (1) ◽  
pp. 13-19 ◽  
Author(s):  
Aristides M. Machado-Rodrigues ◽  
Neiva Leite ◽  
Manuel J. Coelho e Silva ◽  
João Valente-dos-Santos ◽  
Raul A. Martins ◽  
...  
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Metabolic Syndrome ◽  
Vigorous Physical Activity ◽  
Density Lipoprotein ◽  
Metabolic Risk Factors ◽  
Metabolic Risk ◽  
Lifestyle Behaviors ◽  
Increased Risk ◽  
Run Test

Background:Associations of metabolic syndrome (MetS) with lifestyle behaviors in youth is potentially important for identifying subgroups at risk and encourage interventions. This study evaluates the associations among the clustering of metabolic risk factors and moderate-to-vigorous physical activity (MVPA) in youth.Methods:The sample comprised 522 girls and 402 boys (N = 924) aged 11 to 17 years. Height, weight, waist circumference (WC), fasting glucose, high-density lipoprotein cholesterol, triglycerides, and blood pressures were measured. Cardiorespiratory fitness (CRF) was assessed using the 20-m shuttle run test. MVPA was estimated with a 3-day diary. Outcome variables were statistically normalized and expressed as z scores. A clustered metabolic risk score was computed as the mean of z scores. Multiple linear regression was used to test associations between metabolic risk and MVPA by sex, adjusted for age, WC, and CRF.Results:After adjustment for potential confounders, MVPA was inversely associated with the clustering of metabolic risk factors in girls, but not in boys; in addition, after adjusting for WC, the statistical model of that relationship was substantially improved in girls.Conclusion:MVPA was independently associated with increased risk of MetS in girls. Additional efforts are needed to encourage research with different analytical approach and standardization of criteria for MetS in youth.

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