Oncological Study of Thin Layers of Imatinib Molecule Nanostructure for Chronic Myelogenous Leukemia (CML), Acute Lymphocytic Leukemia (ALL), Philadelphia Chromosome-Positive (Ph+), Gastrointestinal Stromal Tumors (GIST), Hypereosinophilic Syndrome (HES), Chronic Eosinophilic Leukemia (CEL), Systemic Mastocytosis and Myelodysplastic Syndrome Treatment

2020 ◽  
Vol 12 (6) ◽  
pp. 753-760
Author(s):  
Alireza Heidari
Keyword(s):  
Temperature Distribution ◽  
Normal Tissue ◽  
Hypereosinophilic Syndrome ◽  
Thin Layers ◽  
Myelogenous Leukemia ◽  
Nano Particles ◽  
Maximum Temperature ◽  
Hyperthermia Treatment ◽  
Wave Source ◽  
Magnetic Nano Particles

The interest in exploring more effective methods for cancer treatment has increased widely in recent years. In clinical studies it is difficult to determine the temperature distribution in both normal tissue and in tumor during hyperthermia treatment since temperature can be measured in limited number of positions in tissue or tumor. Simulation studies can play crucial role in physician's perception of the temperature distribution in tissue. Hyperthermia treatment is facing some unsolved problems such as the appropriate dosage of magnetic Nano particles required to achieve the optimum temperature which results in apoptosis in tumor cells. In this study, a 2D computational model is created in COMSOL Metaphysics in order to analyze temperature distribution in both normal tissue and tumor during hyperthermia treatment using various dosages of magnetic Nano particles. Temperature distribution is achieved by considering various layers from wave source through to the tumor and also by taking into account the amount of heat generated through the Brownian rotation and the Neel relaxation. Simulations of a spherical tumor located in ellipse tissue were designed. A systematical variation in dosage has been performed. Temperature distribution and maximum temperature in steady state and effect of the dosage of Nano particles.

ON-LINE CHARACTERIZATION OF MAGNETIC NANO PARTICLES - SIMULATION VERSUS EXPERIMENT

2001 ◽  
Vol 32 ◽  
pp. 385-386
Author(s):  
TH. KAUFFELDT ◽  
E. KAUFFELDT ◽  
T. ZARUTSKAYA ◽  
M. SHAPIRO ◽  
A. SCHMIDT-OTT
Keyword(s):  
Nano Particles ◽  
On Line ◽  
Magnetic Nano Particles

Comparative study of three magnetic nano-particles (FeSO4, FeSO4/SiO2, FeSO4/SiO2/TiO2) in plasmid DNA extraction

2016 ◽  
Vol 513 ◽  
pp. 68-76 ◽  
Author(s):  
H. Rahnama ◽  
A. Sattarzadeh ◽  
F. Kazemi ◽  
N. Ahmadi ◽  
F. Sanjarian ◽  
...  
Keyword(s):  
Comparative Study ◽  
Dna Extraction ◽  
Plasmid Dna ◽  
Nano Particles ◽  
Magnetic Nano Particles

Effects of Fe3O4 Nano Particles Addition in High Temperature Superconductor YBa2Cu3O7-δ

2012 ◽  
Vol 501 ◽  
pp. 309-313 ◽  
Author(s):  
Siti Nurdalila Abd-Ghani ◽  
Roslan Abd-Shukor ◽  
Wei Kong
Keyword(s):  
Transport Properties ◽  
Solid State Reaction Method ◽  
Nano Particles ◽  
Magnetic Impurities ◽  
Oxide Powders ◽  
Nano Fe3o4 ◽  
Activated Flux ◽  
Average Size ◽  
Increasing Temperature ◽  
Magnetic Nano Particles

The effects of nano particles Fe3O4 addition on the superconducting and transport properties of YBa2Cu3O7-δ (YBCO) were studied. YBa2Cu3O7-δ superconductor powders were prepared by using high purity oxide powders via solid state reaction method. Nano Fe3O4 with 0.01 – 0.05 wt.% with average size 28 nm was added into YBCO. The transition temperatures (Tc) of the samples were measured by using four point probe method. The critical current (Ic) of the samples has been determined by using the 1 μV/cm criterion from 30 – 77 K. Sample with 0.02 wt.% nano Fe3O4 showed the highest Tc at 87 K. It is interesting to note the same sample also exhibited the highest Jc at 77 K up to 1683 mA/cm2. Nano Fe3O4 has acted as effective flux pinning centers in YBCO. A small amount of nano particles Fe3O4 addition has successfully improved the superconducting and transport properties of YBCO. The excessive addition of nano Fe3O4 (> 0.02 wt.%) suppressed the Tc and Jc. Overall, Jc decreases with increasing temperature (30 – 77 K) as a consequence of thermally activated flux creep. Magnetic impurities normally suppress superconductivity. However, by adding magnetic nano particles, current carrying capacity of superconductors YBCO was enhanced significantly.

Electromagnetic performance and thermal analysis of a novel permanent magnet fluxed-switching coupler

2021 ◽  
pp. 1-18
Author(s):  
Lezhi Ye ◽  
Yulong Zhang ◽  
Mingguang Cao
Keyword(s):  
Temperature Distribution ◽  
Permanent Magnet ◽  
Permanent Magnets ◽  
Three Dimensional ◽  
Load Condition ◽  
Maximum Load ◽  
Maximum Temperature ◽  
The Novel ◽  
Transient Field ◽  
Three Dimensional Finite Element

To solve the problem of complex operating device and permanent magnets (PMs) demagnetization at high temperature, a new type of permanent magnet fluxed-switching coupler (PMC) with synchronous rotating adjuster is proposed. Its torque can be adjusted by rotating a switched flux angle between the adjuster and PMs along the circumferential direction. The structural feature and working principle of the PMC are introduced. The analytical model of the novel PMC was established. The torque curves are calculated in transient field by using the three-dimensional finite element method (3-D FEM). The temperature distribution of the novel PMC under rated condition is calculated by 3-D FEM, and the temperature distribution of the PM is compared with that of the conventional PMC. The simulation and test results show that the maximum temperature of copper disc and PM of the novel PMC are 100 °C and 48 °C respectively. The novel PMC can work stably for a long time under the maximum load condition.

scholarly journals Research on Influence of Different Simulation Methods of Bypass Flow in Thermal Hydraulic Analysis on Temperature Distribution in HTR-10

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Shiyan Sun ◽  
Youjie Zhang ◽  
Yanhua Zheng
Keyword(s):  
Temperature Distribution ◽  
Reactor Core ◽  
Flow Distribution ◽  
Maximum Temperature ◽  
Flow Ratio ◽  
Hydraulic Analysis ◽  
Bypass Flow ◽  
Pebble Bed ◽  
The Core ◽  
Thermal Hydraulic Analysis

In pebble-bed high temperature gas-cooled reactor, gaps widely exist between graphite blocks and carbon bricks in the reactor core vessel. The bypass helium flowing through the gaps affects the flow distribution of the core and weakens the effective cooling of the core by helium, which in turn affects the temperature distribution and the safety features of the reactor. In this paper, the thermal hydraulic analysis models of HTR-10 with bypass flow channels simulated at different positions are designed based on the flow distribution scheme of the original core models and combined with the actual position of the core bypass flow. The results show that the bypass coolant flowing through the reflectors enhances the heat transfer of the nearby components efficiently. The temperature of the side reflectors and the carbon bricks is much lower with more side bypass coolant. The temperature distribution of the central region in the pebble bed is affected by the bypass flow positions slightly, while that of the peripheral area is affected significantly. The maximum temperature of the helium, the surface, and center of the fuel elements rises as the bypass flow ratio becomes larger, while the temperature difference between them almost keeps constant. When the flow ratio of each part keeps constant, the maximum temperature almost does not change with different bypass flow positions.

The Effect of Curvature and Torsion on the Temperature Distribution in a Helix

1985 ◽  
Vol 52 (3) ◽  
pp. 529-532 ◽  
Author(s):  
D. D. Sayers ◽  
M. C. Potter
Keyword(s):  
Differential Equation ◽  
Finite Element Method ◽  
Partial Differential Equation ◽  
Temperature Distribution ◽  
Strong Dependence ◽  
Maximum Temperature ◽  
Nonuniform Heating ◽  
The Finite Element Method ◽  
Curvature Parameter ◽  
Curvature And Torsion

Traditional analysis treats the helix as a straight wire with the effects of nonuniform heating, torsion, and large curvature ignored. Using a helical coordinate system the governing partial differential equation including these effects is derived. The equation is then solved numerically using the finite element method. The results indicate a strong dependence of the temperature on the torsion parameter when the curvature parameter is significant. As the curvature parameter increases, the temperature distribution becomes skew-symmetric and the maximum temperature in the helix increases. Nonuniform heating influences the temperature distribution independent of the curvature and torsion.

scholarly journals Heat Localization in the Medium in Blow-Up Regime

2020 ◽  
Keyword(s):  
Temperature Distribution ◽  
Blow Up ◽  
Maximum Temperature ◽  
Heating Regime ◽  
Heating And Cooling ◽  
Localized Heating ◽  
Finite Period ◽  
Equation Of Heat Conduction ◽  
The Given ◽  
Heat Front

The existence of the effect of heat metastable localization in the medium in the blow-up heating regime was experimentally proved. This is the regime in which the heating energy for a finite period of time tends to infinity. Previous theoretical studies have shown that in this case some regions, inside of which the temperature increases, may arise, while their size remains constant or decreases with time (heat localization regions). These regions exist as long as there is some energy input from the outside. An installation for the experimental study of the thermal blow-up regimes in a solid was developed. The object of research was an aluminum rod with a heater at its end. The temperature distribution along the rod was measured with thermocouples. The temperature of the rod end could vary according to the given law. Calibration of the installation was performed. The sensitivity of thermocouples was determined. The inertia of the heating and cooling process was estimated. The mathematical description of the thermal processes, occurring during the experiment, was made. The nonlinear equation of heat conduction for the rod was solved, with the heat exchange with the environment by convection and radiation taken into account. The thermal regime at the boundary, which is necessary to create the thermal structures, was determined. The temperature distribution in the rod in the blow-up regime and non-blow-up regime was measured. In the blow-up regime the heat front (the coordinate of the point with the temperature equal to half the maximum temperature) initially shifts from the heat source, and then in the opposite direction, and the size of the area under heating decreases. In the non-blow-up regime the size of the heated region increases all the time. The predicted effect was supposed to be used in installations for thermonuclear fusion where the target was heated by laser radiation pulses of a special shape. This effect can also be used for localized heating in cutting and welding, when the adjacent regions are not to get very hot, and in other similar situations.

Parameters Control for Properties of Ferrofluid Used in Series Ferrofluid Sensor

2012 ◽  
Vol 248 ◽  
pp. 594-598
Author(s):  
Gang Zhao ◽  
Hai Rong Cui ◽  
Qiu Li Ding ◽  
Xu Feng Wang ◽  
Shi Xi Tian ◽  
...  
Keyword(s):  
Magnetization Curve ◽  
Ph Value ◽  
Nano Particles ◽  
Molar Ratio ◽  
Magnetic Intensity ◽  
Iron Ion ◽  
Ferrous Chloride ◽  
Bivalent Iron ◽  
In Series ◽  
Magnetic Nano Particles

Series ferrofluid based sensors are novel sensors which use ferrofluid as inductive core to measure signals. The physical properties of ferrofluid affect mostly on performance parameter of these series sensors. There is several generality regularity for ferrofluid appliedd in series sensors. This paper analyses the generality of parameter controlling for properties of ferrofluid used in series ferrofluid sensors. The working area of magnetization curve of ferrofluid used in series sensors should be in its linear area where the permeability of ferrofluid is considered as a constant. The magnetic nano-particles generally obtained by reaction of ferrous chloride and ferric chloride. With the increment of viscosity and density of ferrofluid, the saturation magnetic intensity of ferrofluid increases. The concentration of reacted solution is better to be 0.6mol/L. Saturation magnet intensity of magnetic nano-partcles is highest as the molar ratio of trivalent iron ion to bivalent iron ion is equal to 1.75. The reacted temperature is better between 65~80°C while PH value of solution is in a weak alkaline state.

scholarly journals Numerical Simulation and Experimental Study on Temperature Distribution of Self-Lubricating Packing Rings in Reciprocating Compressors

2016 ◽  
Vol 2016 ◽  
pp. 1-14 ◽  
Author(s):  
Jia Xiaohan ◽  
Zhang Qingqing ◽  
Feng Jianmei ◽  
Peng Xueyuan
Keyword(s):  
Temperature Distribution ◽  
Pressure Ratio ◽  
Three Dimensional ◽  
Maximum Temperature ◽  
Transfer Model ◽  
Radial Temperature ◽  
Operational Conditions ◽  
External Cooling ◽  
Packing Rings ◽  
Compressor Reliability

The nonuniform abrasion failure and high-temperature thermal failure of packing rings have a significant influence on compressor reliability, particularly that of oil-free compressors. In this study, a test rig was constructed to measure the dynamic temperature of packing rings under different operational conditions in an oil-free reciprocating compressor. The dynamic axial and radial temperature distributions of the packing rings were obtained using an innovative internal temperature testing device that kept the thermocouples and packing box relatively static during compressor operation. A three-dimensional heat transfer model was also developed to analyze the temperature distribution of the packing boxes, piston rod, and cylinder during such operation. Good agreement was observed between the simulation results and experimental data, which showed an average relative error of less than 2.35%. The results indicate that the pressure ratio exerts a significant effect on the axial temperature distribution and determines which packing ring reaches the maximum temperature. They also show the average temperature to rise with an increase in the rotational speed and to fall with an improvement in the external cooling conditions. Finally, the material of the packing rings was found to affect the temperature gradient from their inner to outer surface.

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