Pathophysiology of wound healing and alterations in venous leg ulcers-review

2016 ◽  
Vol 31 (1_suppl) ◽  
pp. 56-62 ◽  
Author(s):  
Joseph D Raffetto
Keyword(s):  
Social Economic ◽  
Well Being ◽  
Leg Ulcers ◽  
Inflammatory Condition ◽  
Leukocyte Activation ◽  
Venous Leg Ulcer ◽  
Vein Wall ◽  
Venous Diseases ◽  
Genetic And Environmental Factors ◽  
And Migration

Venous leg ulcer (VLU) is one of the most common lower extremity ulcerated wound, and is a significant healthcare problem with implications that affect social, economic, and the well-being of a patient. VLU can have debilitating related problems which require weekly medical care and may take months to years to heal. The pathophysiology of VLU is complex, and healing is delayed in many patients due to a persistent inflammatory condition. Patient genetic and environmental factors predispose individuals to chronic venous diseases including VLU. Changes in shear stress affecting the glycocalyx are likely initiating events, leading to activation of adhesion molecules on endothelial cells, and leukocyte activation with attachment and migration into vein wall, microcirculation, and in the interstitial space. Multiple chemokines, cytokines, growth factors, proteases and matrix metalloproteinases are produced. The pathology of VLU involves an imbalance of inflammation, inflammatory modulators, oxidative stress, and proteinase activity. Understanding the cellular and biochemical events that lead to the progression of VLU is critical. With further understanding of inflammatory pathways and potential mechanisms, certain biomarkers could be revealed and studied as both involvement in the pathophysiology of VLU but also as therapeutic targets for VLU healing.

Moral navigation and child fostering in Chiawa, Zambia

Africa ◽  
2021 ◽  
Vol 91 (2) ◽  
pp. 249-269
Author(s):  
Sarah C. White ◽  
Shreya Jha
Keyword(s):  
Economic Status ◽  
Well Being ◽  
Collective Good ◽  
Geographical Proximity ◽  
Birth Parents ◽  
Social Navigation ◽  
Personal Benefit ◽  
Child Fostering ◽  
And Migration ◽  
A Site

AbstractThis article explores the movement of children between households in Zambia as a site of ‘moral navigation’. Moral navigation extends Henrik Vigh's concept of social navigation from contexts of conflict and migration to more socially stable contexts in which well-being depends critically on people's ability to manage relationships. The live, dynamic and mobile character of these relationships means that they require active, real-time cultivation and response. While having practical objectives, these negotiations are also moral, articulated with ideas of what ought to be, and seeking to fulfil sometimes competing ethical projects. Life history interviews present three main perspectives: recollections of times in childhood spent away from birth parents; birth parents’ reflections on having a child living with others; and adults’ accounts of taking in other people's children. Strong norms of kinship unity and solidarity notwithstanding, in practice terms of engagement are differentiated through gender, marital, social and economic status, plus relational and geographical proximity. The pursuit of personal benefit contains the seeds of both contradiction and convergence with the collective good, as a relational understanding of moral selves sees one's own gain as proper, rightful and virtuous when it is realized in and through providing for others.

Pathology and Pathobiology of Pulmonary Hypertension

2017 ◽  
Vol 38 (05) ◽  
pp. 571-584 ◽  
Author(s):  
Peter Dorfmüller ◽  
Christophe Guignabert
Keyword(s):  
Pulmonary Hypertension ◽  
Vascular Inflammation ◽  
Right Heart Catheterization ◽  
Point Of View ◽  
Heart Catheterization ◽  
Pulmonary Endothelium ◽  
Hemodynamic State ◽  
Pulmonary Arterial ◽  
Genetic And Environmental Factors ◽  
And Migration

Pulmonary hypertension (PH) is a hemodynamic state defined by a mean pulmonary artery pressure ≥ 25 mm Hg during resting right heart catheterization. PH can result from precapillary (arterial) or postcapillary (venous) pathophysiological mechanisms. Interestingly, recent PH pathology has shown that pulmonary arterial or pulmonary venous remodelling are rarely independent phenomena, but frequently occur in combined fashion in lungs from patients suffering from different forms of PH, including pulmonary arterial hypertension (PAH). In PAH, it is now becoming clear that aberrant signals present in vessel wall microenvironment, which is largely orchestrated by dysfunctional pulmonary endothelial cells, are key contributors of the pulmonary vascular remodeling process, fostering proliferation, and survival and migration of resident pulmonary vascular cells such as smooth muscle cells, myofibroblasts, and pericytes. In addition, both genetic and environmental factors are also critical in the development of pulmonary vascular inflammation and chronic impairment of the pulmonary endothelium. This article outlines the current understanding of this disease from the point of view of pathology and pathobiology.

Enhancing social indicators research in a forest-dependent community

1999 ◽  
Vol 75 (5) ◽  
pp. 771-780 ◽  
Author(s):  
John Parkins
Keyword(s):  
Social Capital ◽  
Social Indicators ◽  
Well Being ◽  
Statistical Information ◽  
Social Changes ◽  
Policy Makers ◽  
Measure Change ◽  
Local Residents ◽  
And Migration ◽  
Northern Alberta

Forest industry host communities are receiving increased attention from policy makers, academics, and municipal leaders. Recently, this attention is trained on measuring social and economic change at the community level and on identifying and developing avenues to greater community well-being. This paper examines aspects of two common social indicators, employment and migration, in the context of a forest-dependent community in Northern Alberta. By using statistical information along with two other major data sources that include interviews with local residents and a variety of reports from local institutions, specific social changes taking place within the community are described. Readers are cautioned against relying solely on statistical information to measure change and are encouraged to triangulate data with local sources. Such efforts may be more time consuming but the results are likely to provide more important insights into how and why certain communities are prospering while others are struggling. The paper concludes with a discussion of social capital as a crucial dimension of community well-being. Key words: forest-dependent communities, social indicators, employment, migration, mobility, community well-being, social capital

The Moderation Role of Being Valued by Teachers Over the Association Between School Children Motivation and Need for Competition

SAGE Open ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 215824402110441
Author(s):  
Cristina Maria Bostan ◽  
Tudor Stanciu ◽  
Răzvan-Lucian Andronic
Keyword(s):  
School Children ◽  
Social Constructivism ◽  
Social Economic ◽  
Economic Status ◽  
Well Being ◽  
Social Economic Status ◽  
Motivation For Learning ◽  
The Social ◽  
The Family

Concordant with classical theoretical guidelines (i.e., social facilitation, social constructivism theory, and the Pygmalion effect) we tested the need for competition and perception of being valued by teachers to be better motivated for learning in school. We extend knowledge by testing these associations mediated by the social economic status given by the well-being of the family (i.e., controlling for gender and socio-economic status). A total of 214 Romanian students (45.3% boys) with ages between 13 and 17 years were administered the PEER questionnaire (i.e., perception of being valued by teachers, school-children motivation, and the need for competition). Results show a positive relation between the need for competition and motivation for learning. We also found positive relations between the perception of being valued by the teacher and motivation for learning and the need for competition. We conclude that motivation is higher when the need for competition is higher and the perception of being valued by teachers is higher.

Introduction to the Special Issue: Males of Color and School Counseling

2021 ◽  
Vol 25 (1_part_4) ◽  
pp. 2156759X2110400
Author(s):  
James L. Moore ◽  
Erik M. Hines ◽  
Paul C. Harris
Keyword(s):  
Socioeconomic Status ◽  
School Counseling ◽  
School Counselors ◽  
Social Economic ◽  
Well Being ◽  
Special Issue ◽  
Policy And Practice ◽  
Qualitative And Quantitative ◽  
Rural Settings ◽  
The Social

The sense of urgency for addressing the concerns of males of color cannot be overstated. The reality of racial discrimination and trauma is present for males of color in urban, suburban, and rural settings and regardless of their socioeconomic status. Such oppressive conditions in education, criminal justice, health, and employment, for example, wreak havoc on their overall well-being and advancement in society. Until the systems constraining the progress of males of color are addressed through substantive policy and practice, the social, economic, and educational struggles will persist. This special issue presents 19 theoretical, qualitative, and quantitative articles focusing specifically on the experiences of males of color in educational settings and the importance of school counselors in helping them to thrive.

But who Will Take Care of the Children? Childcare, Women, and Devalued Labor

1986 ◽  
Vol 168 (3) ◽  
pp. 46-69 ◽  
Author(s):  
Kathy Modigliani
Keyword(s):  
Young Children ◽  
Social Economic ◽  
Teacher Shortage ◽  
Well Being ◽  
Comparable Worth ◽  
High Demand ◽  
The Family ◽  
Career Options ◽  
Childcare Center ◽  
Alternative Solutions

This paper considers the salaries, status, and working conditions of childcare employees. A survey of all childcare center workers in one community, and interviews with others from around the country, suggest that wages in this field are low and fringe benefits are rare. Workers' frustrations with compensation and lack of opportunity for advancement are balanced by their strong satisfaction gained from working with young children and their parents. But today's high demand for additional providers, together with new career options for women, has produced a teacher shortage that threatens the well-being of young children. Women's pay inequity, the devaluation of young children, and the privatization of the family are explored as social, economic and cultural factors which contribute to the problem. Alternative solutions are considered, including government subsidies for childcare wages and fees; fee increases for high-income parents-, unionization; comparable worth efforts-, and worker-parent-employer-community advocacy.

scholarly journals Regional demographic policy as a component of social well-being of population (on the materials of Primorsky krai)

POPULATION ◽  
2019 ◽  
Vol 22 (4) ◽  
pp. 126-136
Author(s):  
Elena Kostina ◽  
Nadezhda Orlova ◽  
Anastasia Rubina
Keyword(s):  
Young People ◽  
Far East ◽  
Geographical Location ◽  
Well Being ◽  
Highly Qualified ◽  
Primorsky Krai ◽  
Qualified Personnel ◽  
And Migration ◽  
High Level ◽  
Demographic Policy

The relevance of the regional demographic policy study in the Far East is beyond doubt. This article considers the real demographic situation in Primorsky krai and shows that its territory has seen a steady decline in the population due to natural decrease and migration outflow connected with the low standard and quality of life that in turn reduces the attractiveness of the region and makes it particularly vulnerable to global challenges. Attention is paid to the fact that under the conditions of the Russian Federation subjects' differentiation by geographical location, natural resources potential and level of socio-economic development there is no single approach to the regional demographic policy. Differences in the characteristics of the subjects lead to the necessity of developing demographic programs that would take into account the regional specifics, traditions, characteristics and needs of a particular territory. There are presented the results of the author's study of subjective assessments of the social well-being of young people in Primorsky krai and their migration intentions. The data obtained show that a significant part of young people assess the situation in Primorsky krai as unfavorable for further self-realization; the majority of respondents answered that in other regions/countries it would be easier for them to build a career, start a business, and achieve a high level of material well-being. The directions of the regional demographic policy, which allow attracting and retaining highly qualified personnel in the region, are suggested.

Women as Migrants and Missionaries

2014 ◽  
Vol 31 (3) ◽  
pp. 319-339
Author(s):  
Rose Uchem
Keyword(s):  
United States ◽  
United States Of America ◽  
Social Economic ◽  
The United States ◽  
Women Migrants ◽  
Gender Perspective ◽  
The World ◽  
Family Home ◽  
And Migration ◽  
Experiences Of Women

There are some commonalities in the experiences of women, migrants and missionaries.In many cultures of the world marriage makes women leave home, father, mother,brothers, sisters and land “for the sake of the gospel (of love);” though with less assuranceof the manifold blessings and eternal bliss promised the missionary (Mark 10:29).Again like migrants, women leave their own family home and go and make anotherhome in another land. In a few cases, marriage and migration bring improved socialstatus for some though not for others. However, when things go wrong whether in thefamily or in the community women, like migrants, get the blame and the shame fromthe wider population. While always free in theory to go back to their original homes, inreality just as migrants and missionaries, women are not all that free to move at will.Intricate social, economic and psychological ties bind many and limit their options forescape. Against this background and from a gender perspective, this paper examinesthe missiological significance of women’s experiences in a given Nigerian immigrantChristian community in the United States of America.

Spatial pattern of literacy in Baitarani basin, Odisha

2021 ◽  
Vol 67 (2) ◽  
pp. 194-202
Author(s):  
Siva Prasad Panda ◽  
◽  
Kabir Mohan Sethy ◽  
S. N. Tripathy ◽  
◽  
...  
Keyword(s):  
Economic Development ◽  
Social Economic ◽  
Population Control ◽  
Education Programme ◽  
Economic Factors ◽  
Economic Problems ◽  
Socio Economic Development ◽  
Key Variables ◽  
And Migration ◽  
Regional Imbalance

Literacy has traditionally been described as the ability to read and write a simple message with understanding in any language. Literacy in any area was determined largely by a variety of historical, social and economic factors. Literacy brings about fundamental changes in socio-economic development. The disparity in literacy generates several social, economic and political problems, which may threaten the foundation of development. Literacy and education are necessary for human development. It contributes to better income and health of the population. The national adult Education Programme launched countrywide in 1978 has viewed literacy as a means to bring about a fundamental change in socio-economic development. Literacy and education attainment is the key variables influencing fertility, mortality and migration. Therefore, literacy is the decisive factor for the development and population control as well as inequality in literacy tends to lead to several socio-economic problems, which in turn gives rise to regional imbalance. The disparity in literacy generates several social, economic and political problems, which may threaten the foundation of development. The main objective of the present study is to analyze the pattern of literacy and changes in the Baitarani basin, Odisha.

Sign in / Sign up

Export Citation Format

Share Document