scholarly journals Regionalisation: improving the adoption experience in Wales

2017 ◽  
Vol 41 (3) ◽  
pp. 268-278 ◽  
Author(s):  
Alyson Rees ◽  
Phil Hodgson
Keyword(s):  
Policy Research ◽  
Adopted Children ◽  
Current Position ◽  
Wide Range ◽  
Legislative Changes ◽  
Further Development ◽  
Made In

We provide an overview of the National Adoption Service for Wales (NAS) which was launched in November 2014. Further to a 2016 briefing by John Simmonds, Director of Policy, Research & Development at CoramBAAF, on the regionalisation of adoption services in England, we outline the background and legislative changes that have been made in Wales and report on progress so far. We summarise the current position of NAS, drawing on a wide range of consultation and engagement events with adopted children, adopters and practitioners working in the sector. We conclude by identifying future priorities, challenges and areas for further development.

Paper 18: Emission Control by Carburation

1968 ◽  
Vol 183 (5) ◽  
pp. 24-33 ◽  
Author(s):  
G. L. Lawrence
Keyword(s):  
Development Work ◽  
Short Paper ◽  
Intake System ◽  
Wide Range ◽  
Basic Proposition ◽  
The Subject ◽  
Alternative Techniques ◽  
Induced Charge ◽  
Further Development ◽  
Made In

This paper presents basic data and information relating to the experience gained from further development work associated particularly with the application of ‘CDSE’ carburettors and ‘Duplex’ manifold systems to a wide range of engines. It is intended to be read against the background of the earlier papers published on the subject (1) (2)†. No attempt has been made in this short paper to examine particular criteria in depth, especially since many of the developments are still in the experimental stages. The basic proposition presented is that intake system treatment of the induced charge is more viable commercially than alternative techniques to reduce exhaust pollutants below the legislated standards and that close limit fuel metering consistency is in any event indispensable to adequate field results, whatever system be adopted.

Application of TEM to Deformation, Wear, and Fracture of Ceramics

1974 ◽  
Vol 32 ◽  
pp. 472-473
Author(s):  
B. J. Hockey
Keyword(s):  
Wear Resistance ◽  
High Temperature ◽  
Mechanical Behavior ◽  
Brittle Materials ◽  
High Temperature Strength ◽  
Wide Range ◽  
Corrosive Environments ◽  
Further Development

Ceramics, such as Al2O3 and SiC have numerous current and potential uses in applications where high temperature strength, hardness, and wear resistance are required often in corrosive environments. These materials are, however, highly anisotropic and brittle, so that their mechanical behavior is often unpredictable. The further development of these materials will require a better understanding of the basic mechanisms controlling deformation, wear, and fracture.The purpose of this talk is to describe applications of TEM to the study of the deformation, wear, and fracture of Al2O3. Similar studies are currently being conducted on SiC and the techniques involved should be applicable to a wide range of hard, brittle materials.

A Comprehensive Review on C-3 Functionalization of β-Lactams

2019 ◽  
Vol 16 (1) ◽  
pp. 3-16 ◽  
Author(s):  
Reshma Nagpal ◽  
Jitender Bhalla ◽  
Shamsher S. Bari
Keyword(s):  
Scientific Community ◽  
Organometallic Reagent ◽  
Reaction Conditions ◽  
Biological Potential ◽  
Wide Range ◽  
Economic Strategies ◽  
Synthetic Utility ◽  
Recent Advancement ◽  
Equivalent Method ◽  
Made In

Background:A lot of advancement has been made in the area of β-lactams in recent times. Most of the research is targeted towards the synthesis of novel β-lactams, their functionalization and exploring their biological potential. The C-3 functionalization of β-lactams has continued to attract considerable interest of the scientific community due to their utility as versatile intermediates in organic synthesis and their therapeutic applications. This has led to the significant increase in efforts towards developing efficient and economic strategies for C-3 functionalized β-lactams.Objective:The present review aims to highlight recent advancement made in C-3 functionalization of β-lactams.Conclusion:To summarize, functionalization of β-lactams at C-3 is an essential aspect of β-lactam chemistry in order to improve/modify its synthetic utility as well as biological potential. The C-3 carbocation equivalent method has emerged as an important and convenient strategy for C-3 functionalization of β-lactam heterocycles which provides a wide range of β-lactams viz. 3-alkylated β-lactams, 3-aryl/heteroarylated β-lactams, 3- alkoxylated β-lactams. On the other hand, base mediated functionalization of β-lactams via carbanion intermediate is another useful approach but their scope is limited by the requirement of stringent reaction conditions. In addition to this, organometallic reagent mediated α-alkylation of 3-halo/3-keto-β-lactams also emerged as interesting methods for the synthesis of functionalized β-lactams having good yields and diastereoselectivities.

scholarly journals Multiplexed Genetic Analysis Using an Expanded Genetic Alphabet

2004 ◽  
Vol 50 (11) ◽  
pp. 2019-2027 ◽  
Author(s):  
Scott C Johnson ◽  
David J Marshall ◽  
Gerda Harms ◽  
Christie M Miller ◽  
Christopher B Sherrill ◽  
...  
Keyword(s):  
Newborn Screening ◽  
Cftr Gene ◽  
Transmembrane Conductance Regulator ◽  
Transmembrane Conductance ◽  
Genetic Tests ◽  
Wide Range ◽  
Additional Base ◽  
A Prospective Study ◽  
Cystic Fibrosis Transmembrane ◽  
Made In

Abstract Background: All states require some kind of testing for newborns, but the policies are far from standardized. In some states, newborn screening may include genetic tests for a wide range of targets, but the costs and complexities of the newer genetic tests inhibit expansion of newborn screening. We describe the development and technical evaluation of a multiplex platform that may foster increased newborn genetic screening. Methods: MultiCode® PLx involves three major steps: PCR, target-specific extension, and liquid chip decoding. Each step is performed in the same reaction vessel, and the test is completed in ∼3 h. For site-specific labeling and room-temperature decoding, we use an additional base pair constructed from isoguanosine and isocytidine. We used the method to test for mutations within the cystic fibrosis transmembrane conductance regulator (CFTR) gene. The developed test was performed manually and by automated liquid handling. Initially, 225 samples with a range of genotypes were tested retrospectively with the method. A prospective study used samples from >400 newborns. Results: In the retrospective study, 99.1% of samples were correctly genotyped with no incorrect calls made. In the perspective study, 95% of the samples were correctly genotyped for all targets, and there were no incorrect calls. Conclusions: The unique genetic multiplexing platform was successfully able to test for 31 targets within the CFTR gene and provides accurate genotype assignments in a clinical setting.

scholarly journals Dust Explosion Prevention and Mitigation, Status and Developments in Basic Knowledge and in Practical Application

2009 ◽  
Vol 2009 ◽  
pp. 1-12 ◽  
Author(s):  
Rolf K. Eckhoff
Keyword(s):  
Process Design ◽  
Basic Knowledge ◽  
Industrial Plant ◽  
Practical Application ◽  
Process Industries ◽  
Wide Range ◽  
Firm Knowledge ◽  
Systematic Education ◽  
Training Of Personnel ◽  
Made In

Right from the early days of the process industries, continuous efforts have been made to develop and improve measures for prevention and mitigation of dust explosions in these industries. Nevertheless this hazard continues to threaten industries that manufacture, use and/or handle powders and dusts of a wide range of combustible materials. To improve methods for predicting explosion development in real industrial plant has been one major challenge. Hence, during the last years comprehensive numerical simulation codes, for addressing this problem, have been developed. Progress has also been made in other areas, for example, ignition source prevention. The importance of adopting inherently safer process design, by building on firm knowledge in powder science and technology, and of systematic education/training of personnel, is also emphasized.

Experimental Investigations on Aluminium Ultrasonic Welding Parameters

2014 ◽  
Vol 657 ◽  
pp. 306-310
Author(s):  
Lăcrămioara Apetrei ◽  
Vasile Rață ◽  
Ruxandra Rață ◽  
Elena Raluca Bulai
Keyword(s):  
Microstructural Analysis ◽  
Base Material ◽  
Welding Process ◽  
Ultrasonic Welding ◽  
Experimental Investigations ◽  
Welding Parameters ◽  
Material Structure ◽  
Welding Temperature ◽  
Wide Range ◽  
Made In

Research evolution timely tendencies, in the nonconventional technologies field, are: manufacture conditions optimization and complex equipments design. The increasing of ultrasonic machining use, in various technologies is due to the expanding need of a wide range materials and high quality manufacture standards in many activity fields. This paper present a experimental study made in order to analyze the welded zone material structure and welding quality. The effects of aluminium ultrasonic welding parameters such as relative energy, machining time, amplitude and working force were compared through traction tests values and microstructural analysis. Microhardness tests were, also, made in five different points, two in the base material and three in the welded zone, on each welded aluminium sample. The aluminum welding experiments were made at the National Research and Development Institute for Welding and Material Testing (ISIM) Timişoara. The ultrasonic welding temperature is lower than the aluminium melting temperature, that's so our experiments reveal that the aluminium ultrasonic welding process doesn't determine the appearance of moulding structure. In the joint we have only crystalline grains deformation, phase transformation and aluminium diffusion.

China’s shadow banking sector: beneficial or harmful to economic growth?

2015 ◽  
Vol 7 (4) ◽  
pp. 421-445 ◽  
Author(s):  
James R. Barth ◽  
Tong Li ◽  
Wen Shi ◽  
Pei Xu
Keyword(s):  
Economic Growth ◽  
Banking Sector ◽  
Commercial Banking ◽  
Global Perspective ◽  
Shadow Banking ◽  
Content Type ◽  
Wide Range ◽  
Recent Developments ◽  
Major Factors ◽  
Made In

Purpose – The purpose of this paper is to examine recent developments pertaining to China’s shadow banking sector. Shadow banking has the potential not only to be a beneficial contributor to continued economic growth, but also to contribute to systematic instability if not properly monitored and regulated. An assessment is made in this paper as to whether shadow banking is beneficial or harmful to China’s economic growth. Design/methodology/approach – The authors start with providing an overview of shadow banking from a global perspective, with information on its recent growth and importance in selected countries. The authors then focus directly on China’s shadow banking sector, with information on the various entities and activities that comprise the sector. Specifically, the authors examine the interconnections between shadow banking and regular banking in China and the growth in shadow banking to overall economic growth, the growth in the money supply and the growth in commercial bank assets. Findings – Despite the wide range in the estimates, the trend in the size of shadow banking in China has been upward over the examined period. There are significant interconnections between the shadow banking sector and the commercial banking sector. Low deposit rate and high reserve requirement ratios have been the major factors driving its growth. Shadow banking has been a contributor, along with money growth, to economic growth. Practical implications – The authors argue that shadow banking may prove useful by diversifying China’s financial sector and providing greater investments and savings opportunities to consumers and businesses throughout the country, if the risks of shadow banking are adequately monitored and controlled. Originality/value – To the authors’ knowledge, this paper is among the few to systematically evaluate the influence of shadow banking on China’s economic growth.

The functions and positions of political parties in consociational democracies: theoretical and empirical contexts

2020 ◽  
pp. 28-33
Author(s):  
O. Morhuniuk
Keyword(s):  
Political Parties ◽  
The Netherlands ◽  
Party System ◽  
Party Competition ◽  
European Countries ◽  
The Past ◽  
Democratic Regimes ◽  
Wide Range ◽  
Key Aspects ◽  
Further Development

An article is devoted to the analysis of the functions and formats of political parties in consociational democracies. In particular, it is defined that parties that represent the interests of certain subcultures in society and that reach a consensus among themselves at the level of political agreements are called segmental. At the same time, parties that encapsulate different subgroups of the society that cooperate inside the party within main features of the consociational theory (grand coalition, mutual veto, proportionality in representations, and independence of segments or society subcultures) are called consociational. The theory of consociationalism has received a wide range of theoretical additions and criticism from political scientists over the past fifty years. And while political parties should have been, by definition, one of the key aspects of research within such democratic regimes (parties are part of large coalitions and agents of representation of certain subcultures), there is very scarce number of literature that focuses on this aspect. Therefore, the presented article provides a description of the functions of political parties that could be observed as inside their subcultures as well as in interaction with other segmental parties. Based on the experience of two European countries in the period of “classical” consociationalism (Belgium and the Netherlands), we explain the functions of the parties we have defined in such societies with examples of relevant consociational practices in them. Simultaneously with the analysis of segmental parties, the article also offers the characteristics of consociational parties. The emergence of such parties has its own institutional and historical features. The way of further development of the party system and the level of preservation of consociational practices makes it possible to understand the nature of changes in the societies. Similarly, the analysis of the forms of party competition and interaction between segmental parties makes it possible to outline the forms of those consociational changes that are taking place in the research countries.

IMPACT OF DIGITAL MARKETING: THE PRESENT SCENARIO IN TELANGANA STATE – AN EMPERICAL STUDY

2021 ◽  
Vol 8 (65) ◽  
pp. 15164-15172
Author(s):  
S. Pratap ◽  
Aziz Fatima
Keyword(s):  
Rural Areas ◽  
Urban Areas ◽  
Digital Marketing ◽  
Rural And Remote ◽  
Remote Areas ◽  
Wide Range ◽  
Rural And Remote Areas ◽  
Telangana State ◽  
The Impact ◽  
Made In

In present scenario of COVID-19, the effect of pandemic on Digital Marketing is visible not only in urban areas but also in rural areas. Customers are searching for various products and services through Google by which they can purchase wide range of products and services to fill their needs and desires at relatively low price. The freedom to select numerous products is available by browsing various websites. Hence this study focuses on Impact of digital marketing particularly in the selected rural areas of Telangana state. This state been formed recently but in the IT sector it is receiving much attention throughout the globe, as many MNC’s are establishing their operations in this state. Therefore, an attempt has been made in this study to find out how the Impact of digital marketing is trickling down in the rural and remote areas of newly formed Telangana state. Hence this study focuses the impact of digital marketing in the selected areas of Telangana state.

scholarly journals A New Version of the Software for the Information System “Scientific Heritage of Russia”

2021 ◽  
Author(s):  
Konstantin Pogorelko
Keyword(s):  
Information System ◽  
Information Retrieval ◽  
Data Structure ◽  
Scientific Heritage ◽  
Further Development ◽  
Made In

The information system “Scientific Heritage of Russia” has been created in stages since 2007. Currently, the existing software does not meet the needs of the system and complicates its further development. It was decided to implement the new version of the software in the asp.net core crossplatform environment. The article describes the decisions made in the implementation of software and modernization of the data structure. Particular attention is paid to the development of information retrieval tools.

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