Pharmacy-Led β-Lactam Allergy Interview (BLAI) Reduces Duration of Fluoroquinolones Within a Community Hospital

2019 ◽  
Vol 53 (6) ◽  
pp. 588-595 ◽  
Author(s):  
Elizabeth W. Covington ◽  
Beth Jobson Baldwin ◽  
Emily Warren
Keyword(s):  
Community Hospital ◽  
Skin Testing ◽  
Control Group ◽  
Cohort Design ◽  
Prospective Group ◽  
Before And After ◽  
Effective Option ◽  
Lactam Antibiotic ◽  
Quasi Experimental ◽  
The Impact

Background: Patients with reported β-lactam allergies often receive broad-spectrum antimicrobials and have been shown to experience a variety of negative health consequences, such as increased mortality, costs, readmission, and adverse reactions. Current literature focuses on β-lactam allergy skin testing but lacks evidence on β-lactam allergy interviews (BLAI) when skin testing is unavailable. Objective: This study aimed to test the impact of a pharmacy-led BLAI on duration of fluoroquinolones at a community hospital. Methods: A quasi-experimental design with a prospective cohort design and historical control group was used to assess patients with reported penicillin (PCN) allergies in a community hospital. The primary outcome was duration of fluoroquinolones before and after implementation of BLAI. Secondary outcomes included length of stay (LOS), percentage of patients switched to a β-lactam antibiotic, percentage of antimicrobial stewardship recommendations made/accepted, and discrepancies between allergy in medical record and interview-reported allergy. Nonparametric continuous data and medians were evaluated by Mann-Whitney U. Results: A total of 80 patients were included in the study (43 in the control group and 37 in the prospective group). Fluoroquinolone duration was reduced after the implementation of BLAI (3.7 vs 2.7 days, P = 0.027). In all, 49% of patients in the prospective group were switched to a β-lactam antibiotic after BLAI, with no allergic reactions, adverse effects, or impact on LOS. Conclusion and Relevance: BLAI resulted in a significant reduction in fluoroquinolone duration in patients with PCN allergies and may represent a safe and effective option for institutions lacking skin-testing capabilities.

scholarly journals The Use of Procalcitonin as a Sepsis Marker in a Community Hospital

2019 ◽  
Vol 3 (4) ◽  
pp. 545-552
Author(s):  
Nathalia De Oro ◽  
Maria E Gauthreaux ◽  
Julie Lamoureux ◽  
Joseph Scott
Keyword(s):  
Lactic Acid ◽  
Length Of Stay ◽  
Community Hospital ◽  
Unit Length ◽  
Hospital Setting ◽  
Control Group ◽  
Before And After ◽  
Quasi Experimental ◽  
Current Cutoff ◽  
The Impact

Abstract Background Procalcitonin (PCT) is a biomarker that shows good sensitivity and specificity in identifying septic patients. Methods This study investigated the diagnostic accuracy of PCT in a community hospital setting and how it compared to that of lactic acid. It explored the impact on patient care before and after PCT implementation regarding costs and length of stay. Two comparative groups were analyzed using an exploratory descriptive case–control study with data from a 19-month period after PCT implementation and a retrospective quasi-experimental study using a control group of emergency department patients diagnosed with sepsis using data before PCT implementation. Results Post-procalcitonin implementation samples included 165 cases and pre-procalcitonin implementation sample included 69 cases. From the 165 sepsis cases who had positive blood cultures, PCT had a sensitivity of 89.7%. In comparison, lactic acid's sensitivity at the current cutoff of 18.02 mg/dL (2.0 mmol/L) was 64.9%. There was a 32% decrease in median cost before and after PCT implementation, even with the length of stay remaining at 5 days in both time periods. Conclusions There was a significant decrease after the implementation of PCT in cost of hospitalization compared to costs before implementation. This cost is highly correlated with length of stay; neither the hospital nor the intensive care unit length of stay showed a difference with before and after implementation. There was a positive correlation between lactic acid and PCT values. PCT values had a higher predictive usefulness than the lactic acid values.

scholarly journals The Impact of Education on Mother’s Knowledge for Stunting Prevention Through Moringa Oleifera in Kuan Noel Village, Fatumnasi District, South Central Timor Regency

2020 ◽  
Vol 8 (3) ◽  
pp. 206
Author(s):  
IRLIN FALDE RITI
Keyword(s):  
Treatment Group ◽  
Moringa Oleifera ◽  
Sampling Technique ◽  
Control Group ◽  
South Central ◽  
Significant Difference ◽  
Before And After ◽  
Quasi Experimental ◽  
The Impact ◽  
Educational Aspect

<p align="center"><strong>ABSTRAK</strong></p><p><strong>Background:</strong> One of nutritious problems susceptibly encountred in the world nowadays is kid’s stunting. Stunting is a failure of growth condition and cronical nutritious problems caused by poor nutritious supply because of improper meal provisions in long term growth consumptions. Stunting could be primarily prevented by increasing knowledge about stunting prevention through consuming moringa oleifera regularly. <strong>The aim:</strong> This study is intended to know the impact of education on mother’s knowledge for stunting prevention through regular moringa oleifera consumption. <strong>Research Method: </strong>This research applied a quasi experimental design by generating non equivalent control group which complied two groups; 30 subjects (mothers) were considered as treatment group; whereas, other 30 subjects (mothers) were taken as control group. Thus sampling technique applied was consecutive sampling. <strong>Results:</strong> The study showed that there was a significant impact on education score before and after intervention effects towards the treatment group (p=0,000); whereas there was no significant difference on the control group (p=0,184). The statistical analysis applied independent sample t-test which showed if educational aspect significantly impacted on the increase of mother’s knowledge (p=0,000). <strong>Conclusion:</strong> Educational aspect impacted on mother’s knowledge for stunting prevention through moringa oleifera.</p>

scholarly journals The Impact of Information Technology on Family Values Transformation

2017 ◽  
Vol 2 (4) ◽  
pp. 153
Author(s):  
Bagus Haryono
Keyword(s):  
Information Technology ◽  
Positive Impact ◽  
Family Values ◽  
Personal Contact ◽  
Control Group ◽  
Technology Application ◽  
Message Service ◽  
Before And After ◽  
Quasi Experimental ◽  
The Impact

This research explains the impact of Contemporary Information Technology Application Progress (CITA-P), WhatsApp/WA application, in transforming the family values from face-to-face contact (Emotional and Personal Value or EPV) to non-personal contact (Pragmatic Value or PV). It uses quasi-experimental design conducted by pre-test, treatment, and post-test in Hagen lineage (HaL) as Experiment Group (EG). Then it compares by Control Group (CG) with the Limited-Treatment (L-T) by phone, Short Message Service/SMS, and Facebook/Fb in Sumer lineage (SuL). Data were collected by sending the Eid messages. Respondent consisted of HaL and SuL members. Contemporary treatment is manipulated by CITA-P at the HaL member. Findings showed that CITA-P has positive impact to transform the EPV toward PV, as indicated by significant increase in the larger IT-P score in the EG than the L-T effect in CG before and after implementing it.

scholarly journals 1003. Impact of a Standardized Pharmacist-led Β-lactam Allergy Interview on the Quality of Allergy Documentation

2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S353-S353
Author(s):  
Cynthia T Nguyen ◽  
Oumaima Sahbani ◽  
Jennifer Pisano ◽  
Ken Pursell ◽  
Natasha N Pettit
Keyword(s):  
Primary Outcome ◽  
Skin Testing ◽  
Hospital Costs ◽  
Antibiotic Use ◽  
Pharmacist Intervention ◽  
Lactam Antibiotic ◽  
Quasi Experimental ◽  
Secondary Endpoints ◽  
The Impact

Abstract Background Reported β-lactam allergies are common and are associated with inappropriate antibiotic therapy, poor clinical outcomes, and increased hospital costs. Documentation of β-lactam reactions is often incomplete and many patients with a reported allergy can tolerate a β-lactam antibiotic. This study aims to evaluate the impact of a standardized interviewing tool used by pharmacists on the quality of β-lactam allergy documentation. Methods This is a single-center, prospective, quasi-experimental study of adult inpatients. Patients were included if they had a documented β-lactam allergy, were interviewed by a pharmacist utilizing a standardized tool, and had the β-lactam allergy updated in the electronic medical record. The primary outcome was the percentage of patients with a complete allergy history documented. A complete allergy history was defined as including a description of the type of reaction, time of the reaction, and timing of the reaction. Secondary endpoints included the documentation of individual allergy history components, including if interventions were required to manage the reaction, tolerance of other β-lactams and receipt of penicillin skin testing in the past. A subgroup analysis was also performed among patients who received antibiotics during the admission evaluating antibiotic use, length of stay, mortality, and readmission. Results The study included 107 patients. The average time to complete an interview was 14.8 minutes. After the interview, 11 (10%) patients had the β-lactam allergy label removed. Consequently 107 allergy labels were evaluated in the pre-interview arm and 96 allergy labels in the post-interview arm. More patients had a documented complete allergy history after pharmacist intervention (39% vs. 0%, P &lt; 0.001). Documentation of all components of the allergy history improved after the interview (Table 1). Additionally, the amount of patients with an unknown reaction significantly declined (21% vs. 6%, P = 0.004). Conclusion The use of a standardized β-lactam allergy interview tool improved the quality of allergy documentation, led to de-labeling of β-lactam allergies, and reduced the amount of unknown reactions. Disclosures All authors: No reported disclosures.

scholarly journals PROMOSI MEDIA FILM BERBAHASA BENGKULU BERPENGARUH TERHADAP PENGETAHUAN DAN MOTIVASI WANITA DALAM DETEKSI DINI KANKER SERVIKS MELALUI IVA TES

2019 ◽  
Vol 6 (2) ◽  
pp. 123-132
Author(s):  
Lusi Andriani ◽  
Sri Yanniarti ◽  
Desi Widiyanti ◽  
Elvi Destariyani
Keyword(s):  
Cervical Cancer ◽  
Comparison Group ◽  
Intervention Group ◽  
Control Group ◽  
P Value ◽  
Design Data ◽  
Control Group Design ◽  
Before And After ◽  
Quasi Experimental ◽  
The Impact

The incidence of Cervical cancer about 16/ 100,000 women, 70% of deaths occur in poor and developing countries. It is estimated that approximately 528,000 new cases of cervical cancer and caused 266,000 people to die. The purpose of this study to determine the impact of local language movies on knowledge and motivation Women in the implementation of early detection of cervical cancer by the IVA test. This study uses a quantitative method with a design quasi-experimental pre and post-test with control group design, data were collected using a questionnaire. Samples were 60 women in the Kampung Melayu district area consists of 30 people as the intervention group and 30 in the comparison group. The data analysis used univariate, the bivariate test of T-dependent and T-test Independent, multivariate use MANCOVA. Results showed knowledge before and after intervention increased from 10.73 into 12.80 with p-value(0.000) and Motivation scores increase of 56.57 into 60.40 with p-value (0.002). There are significant differences between the intervention group and the comparison group with p-value(0.002) for the knowledge and p (0.000) for motivation. There was a significant effect of the variable Independent Movie towards Knowledge and Motivation women with pValue 0.00, covariate variable does not affect the knowledge and motivation with p-Value greater than α =0.05. Need to campaign on an ongoing basis to be able to motivate women in carrying out the examination IVA and the media that is used needs to be varied so that women interested and more easily understand the message.

The Effect of Using Proposed Software by the Students of Instructional Technology to Acquire New Instructional Technology Skills

2021 ◽  
Vol 13 (45) ◽  
pp. 125-146
Author(s):  
Dawood Abdulmalek Al-Hidabi ◽  
Eissa Mohammed Ali Saleh
Keyword(s):  
Instructional Technology ◽  
Control Group ◽  
Technology Skills ◽  
Technology Students ◽  
Before And After ◽  
Quasi Experimental ◽  
And Control ◽  
The Impact ◽  
Self Learning ◽  
Academic Year

This study investigated the effect of using proposed software by the students of Instructional Technology Department to acquire new instructional technology skills. To achieve the study objectives, the quasi-experimental research with both experimental and control groups was conducted among 40 second-level students of the Instructional Technology Department at Ibb University in the academic year 2018-2019. Participants took pre and post-tests in order to compare the statistical difference before and after the implementation of the proposed software. The research instrument used in this study was an observation card to measure the extent to which students have acquired the new instructional technology skills. After developing a list of new instructional technology skills, building the proposed software and conducting the treatment, the results showed that students in the experimental group were better than the control group in acquiring the new instructional technology skills. These results demonstrated the impact of using the proposed software for acquiring the new instructional technology skills compared to the conventional methods. The study recommended computerizing specialization courses of the Instructional Technology Department, using self-learning methods that would help students acquire better skills so as to improve and develop the learning process. Keywords: proposed software, new instructional technology skills, Instructional Technology students.

scholarly journals School-Based Training for Sustainable Emotional Development in Chinese Preschoolers: A Quasi-Experiment Study

2021 ◽  
Vol 13 (11) ◽  
pp. 6331
Author(s):  
Jianfen Wu ◽  
Manlin Zhang ◽  
Wenqi Lin ◽  
Yunpeng Wu ◽  
Hui Li
Keyword(s):  
Social Adjustment ◽  
Emotional Competence ◽  
Control Group ◽  
School Based ◽  
Before And After ◽  
Post Test ◽  
Quasi Experimental ◽  
And Control ◽  
The Impact ◽  
Experimental Group

Emotional competence (EC) is important for children’s social adjustment and sustainable development. The present study designed a school based emotional competence learning (ECL) program and examined its effectiveness with 56 Chinese preschoolers aged 5–6. A quasi-experimental design was employed to examine the impact of the ECL program on young children’s EC. Two upper Kindergarten classes (Daban) for children aged 5–6 were randomly assigned as experimental group (n = 31, 42% girls, Mage = 68.31 months, SD = 3.75) and control group (n = 25, 44% girls, Mage = 68.16 months, SD = 3.77). The experimental group was engaged in a 15-week ECL program, whereas the control group had similar duration courses without emotional competence training. All the children were administered the Test of Emotion Comprehension, Expression Identification Task, and Emotion Regulation Strategy Inventory before and after the intervention. The results indicated no significant differences between the experimental and control groups in the pre-test. In contrast, the experimental group outperformed the control group in most EC components in the post-test. Meanwhile, the experimental group demonstrated greater increases in EC components. The findings suggest that this ECL program has strong potential as a school-based, structured program for enhancing children’s emotional competence. The educational implications of these findings are discussed.

scholarly journals PENDIDIKAN KESEHATAN DALAM PENGELOLAAN HIPERTENSI PADA LANSIA DI POSBINDU BOKESAN NGEMPLAK SLEMAN DIY

2019 ◽  
Vol 6 (3) ◽  
pp. 199-204
Author(s):  
Ignasius Gongo Prihatmono ◽  
Scholastica Fina Aryu Puspasari
Keyword(s):  
Cardiovascular Disease ◽  
Healthy Lifestyle ◽  
Smoking Habit ◽  
Intervention Group ◽  
Control Group ◽  
Hypertension Management ◽  
Before And After ◽  
Quasi Experimental ◽  
Psychomotor Ability ◽  
The Impact

Background: Cardiovascular disease is the leading cause of mortality. The highest prevalence of cardiovascular disease is hypertension. Hypertension prevalence increases in 10 years and WHO predicts that it will always increase until 2030. Hypertension management is needed to prevent any complication and improve patient’s ability in their daily activity. Knowledge about hypertension management is based of healthy lifestyle that affected their quality of life. Objective: this study focused on determining the impact of education on respondent’s cognitive, affective, and psychomotor ability. Methods: this study occupied quasi-experimental design, which involve 40 respondents, divided into 2 groups i,e intervention group and control group (20 respondents each). Results: the majority of respondents were male (62.5%), aged 55-64 (50%), middle education (47.5%), non- smoker (55%), had no diet (62.5%). after 4 weeks, significant differences were found in cognitive, affective and psychomotor level before and after intervention in intervention group (p=0.002; p=0.012; p=0.001). compared to control group, there are significant differences in cognitive and psychomotor level (p=0.028; p=0.013). respondents’ characteristics that impacted on the dependent variable were education level, smoking habit, exercise, coping mechanism. Conclusion: education is an effective intervention to improve cognitive and psychomotor level of people with hypertension. Keywords: Education, hypertension, cognitive, psychomotor  

A test of a job demands-resources intervention

2016 ◽  
Vol 31 (3) ◽  
pp. 686-701 ◽  
Author(s):  
Jessica van Wingerden ◽  
Arnold B. Bakker ◽  
Daantje Derks
Keyword(s):  
Work Engagement ◽  
Healthcare Professionals ◽  
Job Demands ◽  
Job Crafting ◽  
Control Group ◽  
Content Type ◽  
Before And After ◽  
Quasi Experimental ◽  
And Performance ◽  
The Impact

Purpose – The purpose of this paper is to examine the impact of a job demands-resources (JD-R) intervention on psychological capital (PsyCap), job crafting, work engagement, and performance. Design/methodology/approach – This study used a quasi-experimental pre-test-post-test design with a control group. Healthcare professionals (n=67) were assigned to the JD-R intervention or a control group and filled out questionnaires before and after the intervention. To test the hypotheses, multivariate analyses of covariance were conducted. Findings – Results showed that participants’ PsyCap, job crafting, work engagement, and self-ratings of job performance significantly increased after the JD-R intervention. Research limitations/implications – Only healthcare professionals participated in the intervention study, which restricts the generalizability of the findings. Practical implications – The results illustrate that organizations can foster work engagement and improve performance by offering a JD-R intervention aimed at increasing PsyCap and job crafting at work. Organizations should acknowledge the importance of facilitating and stimulating a resourceful and challenging work environment. Originality/value – This is the first study that examined a JD-R intervention. The results contribute to JD-R theory by offering a first causal test. For the first time, a significant increase of job crafting behaviors after an intervention was found.

scholarly journals Impact of two bundles on central catheter-related bloodstream infection in critically ill patients

2017 ◽  
Vol 25 (0) ◽  
Author(s):  
Cristobal Felipe Padilla Fortunatti
Keyword(s):  
Bloodstream Infection ◽  
Positive Impact ◽  
Control Group ◽  
Central Catheter ◽  
Before And After ◽  
Quasi Experimental ◽  
Equivalent Control ◽  
Efficient Alternative ◽  
The Impact ◽  
Catheter Related Bloodstream Infection

ABSTRACT Objective: To evaluate the impact of the implementation of insertion and maintenance bundles on the rates of catheter-related bloodstream infection in an intensive care unit. Method: This is a quasi-experimental, before-and-after study with a non-equivalent control group. During a six-month period, insertion and maintenance bundles for the central venous catheters were implemented. Supervision guidelines were developed to assess compliance with the bundle and catheter characteristics. Results: A total of 444 central catheters corresponding to 390 patients were observed, of which 68.7% were inserted in the unit. The maintenance and insertion bundles reached 62.9% and 94.7% compliance, respectively, and 50.7% of the insertions were supervised. It was possible to observe a 54.5% decrease in the rate of central catheter infection (3.48 vs 1.52 x 1000 days/catheter, p<0.05) when compared with the control group. Conclusion: The simultaneous implementation of insertion and maintenance bundles has a positive impact on the reduction of catheter-related bloodstream infection; therefore it is an efficient alternative to improve the quality and safety of care in high complexity units.

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