Agreement analysis comparing iPad LCVA and Sloan testing in multiple sclerosis patients

2017 ◽  
Vol 24 (8) ◽  
pp. 1126-1130 ◽  
Author(s):  
Neda Sattarnezhad ◽  
Samantha Farrow ◽  
Dorlan Kimbrough ◽  
Bonnie Glanz ◽  
Brian Healy ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Visual Acuity ◽  
T Test ◽  
Computerized Testing ◽  
Low Contrast ◽  
Significant Difference ◽  
Increased Sensitivity ◽  
The Right ◽  
Multiple Sclerosis Patients ◽  
Paired T Test

Background: Visual symptoms are common in multiple sclerosis (MS). Low-contrast visual acuity (LCVA) testing using Sloan charts has demonstrated increased sensitivity for visual deficits compared to high-contrast acuity testing. Computerized testing of visual acuity may facilitate use in the clinic setting. Objectives: To evaluate the agreement between an iPad-based and Sloan testing of LCVA in a cohort of MS patients. Methods: A total of 38 patients with relapsing-remitting MS were enrolled after providing informed written consent at Partners MS Center, Brigham and Women’s hospital. Monocular LCVA was measured using retroilluminated Sloan chart and iPad-based LogMAR chart. Number of correct letters and agreement between two measurements were assessed for each eye using Bland–Altman analysis and paired t-test. Results: For both eyes, there was no significant difference in number correct between the two measurements using a paired t-test, and there was high correlation between two measurements (oculus dextrus (OD) r = 0.89, p < 0.001; oculus sinister (OS) r = 0.78, p < 0.001). The limits of agreement were −7.9 to +8.5 letters for the right eye and −10.9 to +11.2 letters for the left eye. Conclusion: An iPad-based LCVA test shows good agreement with Sloan testing in MS patients.

scholarly journals PERBEDAAN PENURUNAN NILAI a*, b* dan L* PADA DAGING AYAM BROILER (Gallus domesticus) AKIBAT OZONASI DAN PEREBUSAN

2019 ◽  
Vol 6 (2) ◽  
pp. 86
Author(s):  
Anita Wilatika Pratama
Keyword(s):  
Broiler Chicken ◽  
Chicken Meat ◽  
Gallus Domesticus ◽  
T Test ◽  
Significant Difference ◽  
The Right ◽  
Paired T Test

Abstrak Penelitian ini bertujuan untuk mengetahui perbedaan penurunan nilai kromatik warna a*, b* dan L* daging ayam hasil ozonasi dan perebusan sehingga didapatkan perlakuan yang tepat. Penelitian dilakukan dengan uji t berpasangan yang terdiri dari 3 perlakuan dan 3 kali pengulangan. Ozonasi dilakukan dengan konsentrasi sebesar 1,5 ppm selama 4 menit dan direndam selama 3 menit. Perebusan dilakukan dengan suhu ±80 0C selama 24 menit. Instrumen diuji menggunakan alat Chromameter CR-400. Hasil menunjukkan bahwa nilai L* (kecerahan) daging ayam hasil ozonasi dan perebusan terdapat perbedaan yang signifikan, nilai a* (kemerahan) daging ayam hasil ozonasi dan perebusan terdapat perbedaan yang signifikan, nilai b* (kekuningan) daging ayam hasil ozonasi dan perebusan terdapat perbedaan yang signifikan. Perlakuan yang tepat untuk mempertahankan nilai a*, b* dan L* daging ayam broiler yaitu dengan cara diozon yang menyebabkan daging lebih cerah, berwarna merah cerah dan tidak kekuningan.  Kata kunci : Ayam; daging; ozonasi; penurunan; perebusan. Abstract This study aims to determine the differences in the reduction of chromatic values of a *, b * and L * ozonation and boiling chicken meat so that the right treatment is obtained. The study was conducted by paired t test consisting of 3 treatments and 3 repetitions. Ozonation was carried out with a concentration of 1.5 ppm for 4 minutes and soaked for 3 minutes. Boiling is carried out at ± 80 0C for 24 minutes. The instrument was tested using a Chromameter CR-400. The results showed that the value of L * (Lightness) of ozonation and boiling chicken meat had a significant difference, the a * (redness) value of ozonation and boiling chicken meat had significant differences, the value of b * (yellowness) of ozonation and boiling chicken meat was significant difference. The right treatment to maintain the values of a *, b * and L * broiler chicken meat is by diozone which causes the meat to be brighter, bright red and not yellowish.  Keywords: boiling; chicken; decrease; meat; ozonation.

Pediatric Cataract Surgery: Comparison between Ages at Surgery and Contrast Sensitivity Outcomes

2019 ◽  
Vol 43 (1) ◽  
pp. 50
Author(s):  
Aquirina Caesari Putri ◽  
Rozalina Loebis
Keyword(s):  
Visual Acuity ◽  
Cataract Surgery ◽  
Contrast Sensitivity ◽  
Cataract Extraction ◽  
Significant Negative Correlation ◽  
Natural World ◽  
P Value ◽  
Pediatric Cataract ◽  
Low Contrast ◽  
Significant Difference

Background: Pediatric cataracts are major causes of children’s blindness. Surgery has proven to be beneficial in terms of visual function prognosis. Contrast sensitivity evaluation after surgery is as important as visual acuity considering that natural world consists of various objects in low-to-medium contrasts. The purpose of this study is to analyze the difference of contrast sensitivity outcomes based on ages at surgery. Method: Retrospective data of children with pediatric developmental cataract from July 2013 to November 2015 were collected. All children who underwent cataract surgery at 60-months-old or less were randomized into two groups, ≤24 months and >24-to-60 months. Contrast sensitivity was then examined with preferential-looking method using Hiding Heidi low-contrast test face chart. The main outcome measures were contrast sensitivity of both groups. Age-at-evaluation, cataract onset, duration of follow-up, duration of deprivation and visual acuity were also noted. Result: Of 14 children (23 eyes), 11 eyes (47,8%) were in ≤24 months group, 12eyes (52,2%) were in >24-to-60 months group. All eyes underwent cataract extraction and similar type of intraocular lens implantation. Mean age-at-surgery was 28,2 months±16,8 (SD). Mean contrast sensitivity for each group was 47,50 %±42,29 and 18,33%±27,38, respectively, with p-value 0,031. Further analysis of Spearman’s correlation test demonstrated significant negative correlation (rs = -0,559; p = 0,006) between the two groups. Conclusion: There was statistically significant difference in contrast sensitivity between those who underwent surgery at ≤24 months and >24-to-60 months. Children who underwent surgery at older ages tend to have better contrast sensitivity afterwards.

The effect of positive thinking training on the quality of life of parents of adolescent with thalassemia

2019 ◽  
Vol 0 (0) ◽  
Author(s):  
Adeleh Sadeghloo ◽  
Parna Shamsaee ◽  
Elham Hesari ◽  
Golbanhar Akhondzadeh ◽  
Hamid Hojjati
Keyword(s):  
Quality Of Life ◽  
Emotional Health ◽  
Intervention Group ◽  
T Test ◽  
World Health ◽  
Positive Thinking ◽  
Significant Difference ◽  
And Control ◽  
Paired T Test

Abstract Introduction Thalassemia, as the most common chronic hereditary blood disorder in humans, can impose many adverse effects on parents and their affected children. On the other hand, positive thinking is the method or the result of a positive focus on a constructive issue, so by teaching positive thinking, we can improve physical and social function, and promote emotional health and overall quality of life. The aim of this study was to determine the effect of positive thinking training on the quality of life of parents of adolescents with thalassemia. Methods This quasi-experimental study was performed on 52 parents of adolescents with thalassemia who attended Taleghani Hospital in Golestan province, Iran in 2017. Samples were randomly assigned into two groups of intervention and control. The positive thinking training (based on the theory of Martin Seligman) was carried out in the intervention group in 10 (45–60 min) sessions over a 5-week period. Data collection tools in this study were the World Health Organization (WHO) quality of life questionnaire (WHOQOL-BREF) and a demographic information questionnaire. Data were analyzed by SPSS-16 software using independent t-test, the paired t-test and a covariance test. Results The results of paired t-test showed a significant difference in the score of quality of life in intervention group before and after the intervention (p < 0.001). However, this test did not show any significant difference in the control group (p = 0.11). The covariance test, after removing the pre-test score, showed a significant difference between the intervention and control groups in terms of the score of quality of life, so that 13% of the changes after the intervention were due to the intervention (p = 0.009, η = 0.13). Conclusion The positive thinking training increased the quality of life of parents of adolescents with thalassemia. Therefore, using this program can be an effective way of improving the quality of life of parents. Thus, positive thinking training is suggested to be used as an effective strategy for increasing the quality of life of parents with ill children.

Effect of Self - Care Program on the Self- Esteem of Multiple Sclerosis Patients

2009 ◽  
Vol 24 (S1) ◽  
pp. 1-1
Author(s):  
H. Madani ◽  
H. Navipoor ◽  
P. Roozbayani
Keyword(s):  
Multiple Sclerosis ◽  
Self Care ◽  
Care Program ◽  
Self Esteem ◽  
The Self ◽  
Self Report ◽  
The Mean ◽  
Muscular Spasm ◽  
Multiple Sclerosis Patients ◽  
Paired T Test

Aims:According to decreased self- esteem in multiple sclerosis (MS) patients, it is necessary to utilize appropriate methods in order to improve self- esteem in MS patients. So this study was conducted on patients with MS supported by the Iranian MS society for determining the effect of self - care program on their self- esteem.Method:In this semi - experimental study 34 patients with MS who were not in the acute phase of disease were selected. The data were collected via personal questionnaires, problem list, Cooper and smith standard questionnaire for self- esteem and self report check lists. Self - care program(self - care for muscular spasm, fatigue, constipation and amnesia and …) was educated, then it was performed for one month period and the data were analyzed using paired t- test, wilcoxon, croscal - wallis and manwithney tests.Results:Application of self - care program improve the self- esteem and reduced some symptoms such as muscular spasm, fatigue, constipation and amnesia in MS patients. The mean valve of self- esteem increased from 54 before performing the program to 68 after the program ( p < 0.05).Conclusion:Using self-care program can be an effective method for improving self- esteem of MS patients.

scholarly journals Multiple sclerosis and depressive manifestations: can diffusion tensor MR imaging help in the detection of microstructural white matter changes?

2019 ◽  
Vol 50 (1) ◽  
Author(s):  
Talaat A. Hassan ◽  
Shaima Fattouh Elkholy ◽  
Bahaa Eldin Mahmoud ◽  
Mona ElSherbiny
Keyword(s):  
Multiple Sclerosis ◽  
Depressive Symptoms ◽  
White Matter ◽  
Limbic System ◽  
Diffusion Tensor ◽  
Control Group ◽  
Uncinate Fasciculus ◽  
White Matter Tracts ◽  
Significant Difference ◽  
The Right

Abstract Background Multiple sclerosis is one of the commonest causes of neurological disability in middle-aged and young adults. Depression in MS patients can compromise cognitive functions, lead to suicide attempts, impair relationships and reduce compliance with disease-modifying treatments. The aim of this study was to investigate and compare the microstructural changes in the white matter tracts of the limbic system in MS patients with and those without depressive manifestations using a diffusion tensor imaging (DTI) technique. Methods This study included 40 patients who were divided into three groups. Group 1 comprised of 20 patients with relapsing-remitting MS with depressive symptoms and group 2 comprised 10 MS patients without symptoms of depression. The third group is a control group that included 10 age-matched healthy individuals. All patients underwent conventional MRI examinations and DTI to compare the fractional anisotropy (FA) values in the white matter tracts of the limbic system. Results We compared the DTI findings in MS patients with and those without depressive symptoms. It was found that patients with depression and MS exhibited a significant reduction in the FA values of the cingulum (P < 0.0111 on the right and P < 0.0142 on the left), uncinate fasciculus (P < 0.0001 on the right and P < 0.0076 on the left) and the fornix (P < 0.0001 on both sides). No significant difference was found between the FA values of the anterior thalamic radiations in both groups. Conclusion Patients with depression and MS showed more pronounced microstructural damage in the major white matter connections of the limbic pathway, namely, the uncinate fasciculus, cingulum and fornix. These changes can be detected by DTI as decreased FA values in depressed MS patients compared to those in non-depressed patients.

scholarly journals EFFECTIVENESS OF GLUTEAL MUSCLE STRENGTHENING ON FLAT FOOT

2017 ◽  
Vol 10 (6) ◽  
pp. 219
Author(s):  
Pooja A Mulchandani ◽  
Trupti Warude ◽  
Amrutkuvar Pawar
Keyword(s):  
T Test ◽  
P Value ◽  
Random Allocation ◽  
Gluteal Muscle ◽  
Flat Foot ◽  
Muscle Strengthening ◽  
Intrinsic Muscle ◽  
Navicular Drop ◽  
Significant Difference ◽  
Paired T Test

Objectives: To compare the effect of gluteal muscle strengthening along with conventional exercises versus conventional exercises alone on flat foot.Method: An experimental study conducted at Physiotherapy Department of Krishna Institute of Medical Sciences, Karad. A total of 52 subjects were equally divided into two groups using convenient sampling with random allocation (Groups A and B). Baseline treatment was given to both groups (intrinsic muscle strengthening). Group A was given intrinsic muscle strengthening alone while Group B was given gluteal muscle strengthening along with intrinsic muscle strengthening.Result: Statistical analysis was performed using paired t-test and unpaired t-test. In pre-intervention there was no statistically significant difference seen with p values for the navicular drop was 0.3563 and for Ink test was 0.7342. While on comparing the post-interventional values, the results between the two groups using paired t-test revealed that there was extremely significant difference seen with p-value for the navicular drop was <0.0001 and for Ink test was <0.0001.Conclusion: From the study, it can be concluded that there was a significant effect of gluteal muscle strengthening on the flat foot.

scholarly journals PERFORMANCE COMPARISON OF LASTON AC-WC BASED ON AGGREGATE GRADATION SPECIFICATIONS

2018 ◽  
Vol 2 (02) ◽  
pp. 151
Author(s):  
Devi Yulita Metasari ◽  
Akhmad Hasanuddin ◽  
Dewi Junita Koesoemawati
Keyword(s):  
Flow Rate ◽  
Outer Layer ◽  
Performance Comparison ◽  
High Flow ◽  
T Test ◽  
Aggregate Gradation ◽  
Significant Difference ◽  
Bitumen Content ◽  
Asphalt Content ◽  
Paired T Test

Laston AC-WC is the outer layer of the pavement that is directly related to the outside, so a strong mixture is required. One of the major effects is the aggregate gradation.This experiment aims to find out the comparison of Laston AC-WC performance between mixtures used aggregat egradation above and below the restriction zone. Each mixture used 6 variations of asphalt content and there were 3 specimens on each variation of bitumen content. The asphalt contents used were 5,5%; 6%; 6,5%; 7%; 7,5% dan 8%. From the results of the experiments, the mixture with the aggregate above the restriction zone at 7% and 7.5% asphalt content had a density value of 2.13 gr / cc and 2.12 gr / cc respectively; VMA value of 15.49% and 15.91%; VFA values ​​of 80.48% and 79.98%; VIM value of 3.16% and 3.18%; stability value of 3013.58 kg and 2332.57 kg; flow value of 2.47 mm and 2.18 mm; as well as MQ values ​​of 1222.25 kg / mm and 1184.59 kg / mm. While on the mixture with the aggregate under the restriction zone in the asphalt content of 7% and 7.5% obtained density value of 2.11 gr / cc and 2.14 gr / cc; VMA value of 17.21% and 16.3%; VFA value of 71.21% and 78.65%; VIM value of 4.99% and 3.49%; stability value of 2518,75 kg and 3234,72 kg; flow values ​​of 2 mm and 2.07 mm; as well as the MQ value of 1259.37 kg / mm and 1623.54 kg / mm. From the results are analyzed Paired T test and found that the value of flow has a significant difference. The high flow rate was found in the mixture with the aggregate above the restriction zone at 7% asphalt content, so this mixture is more durable due to good flexibility. Laston AC-WC merupakan lapisan terluar perkerasan yang berhubungan langsung dengan keadaan luar, sehingga dibutuhkan campuran yang kuat. Salah satu yang berpengaruh besar adalah gradasi agregat yang digunakan. Penelitian ini bertujuan untuk mengetahui perbandingan kinerja laston AC-WC antara campuran yang menggunakan gradasi di atas dengan di bawah daerah larangan. Penelitian ini dilakukan terhadap campuran laston AC-WC. Masing-masing campuran menggunakan 6 variasi kadar aspal dan terdapat 3 benda uji pada setiap kadar aspal. Kadar aspal yang digunakan adalah 5,5%; 6%; 6,5%; 7%; 7,5% dan 8%. Dari hasil penelitian, campuran dengan agregat di atas daerah larangan pada kadar aspal 7% dan 7,5% memiliki nilai density berturut-turut sebesar 2,13 gr/cc dan 2,12 gr/cc; nilai VMA sebesar 15,49% dan 15,91%; nilai VFA sebesar 80,48% dan 79,98%; nilai VIM sebesar 3,16% dan 3,18%; nilai stabilitas sebesar 3013,58 kg dan 2332,57 kg; nilai flow sebesar 2,47 mm dan 2,18 mm; serta nilai MQ sebesar 1222,25 kg/mm dan 1184,59 kg/mm. Sedangkan pada campuran dengan agregat di bawah daerah larangan pada kadar aspal 7% dan 7,5% didapatkan nilai density sebesar 2,11 gr/cc dan 2,14 gr/cc; nilai VMA sebesar 17,21% dan 16,3%; nilai VFA sebesar 71,21% dan 78,65%; nilai VIM sebesar 4,99% dan 3,49%; nilai stabilitas sebesar 2518,75 kg dan 3234,72 kg; nilai flow sebesar 2 mm dan 2,07 mm; serta nilai MQ sebesar 1259,37 kg/mm dan 1623,54 kg/mm. Dari hasil tersebut dilakukan analisa Uji T Berpasangan dan didapatkan bahwa nilai flow memiliki perbedaan yang signifikan. Nilai flow yang tinggi terdapat pada campuran dengan agregat di atas daerah larangan pada kadar aspal 7%, sehingga campuran ini lebih tahan lama dikarenakan memiliki kelenturan yang baik.

scholarly journals Comparison of Copper Level and Color Vision in Pulmonary Tuberculosis Patients Before and After Ethambutol Treatment in Category I and II

2020 ◽  
Vol 3 (1) ◽  
pp. 19-25
Author(s):  
Febria Restissa ◽  
Ahmad Rasyid ◽  
Devi Azri Wahyuni
Keyword(s):  
Color Vision ◽  
Total Error ◽  
T Test ◽  
Wilcoxon Test ◽  
Copper Level ◽  
Tuberculosis Patients ◽  
Vision Disorder ◽  
Significant Difference ◽  
Before And After ◽  
Paired T Test

ABSTRACT Objective : to determine the correlation between duration of ethambutol and copper levels in serum with color vision disorder examined with Farnsworth Munsell 100 Hue (FM100) in patients with tuberculosis. Methods: This study was an explorative observation of 20 samples during November 2017 - January 2018 period. Comparative analysis using independent t-test, paired t-test, Wilcoxon test and Mann-Whitney test, while correlation analysis using Spearman's test and Pearson's test.  Results: There was a significant difference of FM100 value before and after in category I (p=0.000) with increase of total error value 11.80+5.31 or category II (p=0.000) with increase of total error value 15.00+7.41. There was significant difference of Cu2+ level before and after in category I (p=0.005) with decrease of Cu2+ level 15.57+5.04 mg/dL or category II (p=0.005) with decrease of Cu2+ level 31.66+7.35 mg/dL. There was significant correlation between color vision and duration of ethambutol (p=0.000), but there was no significant correlation of Cu2+ with color vision (p>0.05). Conclusion: The duration of Ethambutol was related to changes in color vision examined with FM100.

scholarly journals Analysis The Level Of Cattleman’s Knowledge Using The T-Test And Wilcoxon In Maju Farmer Group

2020 ◽  
Vol 15 (1) ◽  
pp. 1
Author(s):  
Bismi Widi Hastari ◽  
Dyah Gandasari ◽  
Harry Harry
Keyword(s):  
T Test ◽  
Statistical Software ◽  
City Administration ◽  
Group Data ◽  
Significant Difference ◽  
Urine Production ◽  
Before And After ◽  
Post Test ◽  
Level Of Knowledge ◽  
Paired T Test

Tani Maju farmer group is one of the farming groups located in Rorotan Village, Cilincing District, North Jakarta City Administration. This group has a lot of sheep and advanced management. Despite they manage their sheep well, they are not well informed on how to manage the sewage from their castles (faces and urine). So far, they just throw away the sewage or gave them to fellow farmers. This study aimed to analyze the level of farmers' knowledge in making use of sheep's urine to be degraded into bio urine in the Maju Farmer group. Data was collected through the pre-test and post-test. The data were analyzed using paired t-test and Wilcoxon statistical software (IBM SPSS Statistics 25). The results of the study showed that farmers' knowledge in sewage (Urine) management increased; there is a significant difference in farmers' level of knowledge in bio urine production before and after bio urine extension.

scholarly journals Cortical morphology predicts placebo response in multiple sclerosis

2022 ◽  
Vol 12 (1) ◽  
Author(s):  
Mariya V. Cherkasova ◽  
Jessie F. Fu ◽  
Michael Jarrett ◽  
Poljanka Johnson ◽  
Shawna Abel ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Right Hemisphere ◽  
Placebo Response ◽  
Small World ◽  
Lesion Load ◽  
Transient Improvement ◽  
Related Quality ◽  
Brain Correlates ◽  
The Right ◽  
Multiple Sclerosis Patients

AbstractDespite significant insights into the neural mechanisms of acute placebo responses, less is known about longer-term placebo responses, such as those seen in clinical trials, or their interactions with brain disease. We examined brain correlates of placebo responses in a randomized trial of a then controversial and now disproved endovascular treatment for multiple sclerosis. Patients received either balloon or sham extracranial venoplasty and were followed for 48 weeks. Venoplasty had no therapeutic effect, but a subset of both venoplasty- and sham-treated patients reported a transient improvement in health-related quality of life, suggesting a placebo response. Placebo responders did not differ from non-responders in total MRI T2 lesion load, count or location, nor were there differences in normalized brain volume, regional grey or white matter volume or cortical thickness (CT). However, responders had higher lesion activity. Graph theoretical analysis of CT covariance showed that non-responders had a more small-world-like CT architecture. In non-responders, lesion load was inversely associated with CT in somatosensory, motor and association areas, precuneus, and insula, primarily in the right hemisphere. In responders, lesion load was unrelated to CT. The neuropathological process in MS may produce in some a cortical configuration less capable of generating sustained placebo responses.

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