scholarly journals Community-Associated Methicillin-Resistant Staphylococcus aureus Infections in the Athlete

2009 ◽  
Vol 1 (5) ◽  
pp. 405-410 ◽  
Author(s):  
Kathleen Weber
Keyword(s):  
Wound Care ◽  
Clinical Information ◽  
Personal Hygiene ◽  
Prevention Measures ◽  
Effective Prevention ◽  
Methicillin Resistant ◽  
Treatment And Prevention ◽  
Appropriate Treatment ◽  
Prevention Of Infections ◽  
High Level

Context: Community-associated methicillin-resistant Staphlococcus aureus (CA-MRSA) has become of increasing concern in the athletic setting. Appropriate recognition, treatment, and prevention measures are all paramount to protect individual athletes and teamwide outbreaks. Evidence Acquisition: Relevant electronic databases (Medline or PubMed) through 2008 were searched. Articles and studies relevant to this topic were reviewed for pertinent clinical information. Study Type: Clinical review. Results: CA-MRSA is an increasing problem both in the community at large and in the athletic population. Conclusion: Early infections based on methicillin-resistant Staphlococcus aureus are often misidentified, leading to delay in appropriate treatment. A high level of suspicion, prompt recognition, and appropriate treatment can minimize morbidity associated with CA-MRSA. Careful selection of antibiotics in suspected cases is important, with more severe infections requiring hospitalization and intravenous antibiotics. Eradication of bacteria in colonized patients has not yet proven to be effective. Prevention of infections is multifaceted, and it includes education, proper personal hygiene, routine cleaning of equipment, and proper wound care.

scholarly journals Medibot: A Predictive Generic Diabetic Chatbot using Bagging Ensemble/Hybrid Learning

2020 ◽  
Vol 9 (4) ◽  
pp. 1518-1523
Keyword(s):  
Side Effects ◽  
Human Life ◽  
Clinical Information ◽  
Gradient Boosting ◽  
Support Vector ◽  
Prevention Measures ◽  
Vector Machines ◽  
Normal Man ◽  
High Level ◽  
Bagging Ensemble

Clinical chatbots are conversational operators worked in light of clinical applications. They can possibly lessen medicinal services costs and improve availability of clinical information to basic man. There are different methods accessible for planning chatbots for anticipating an infection. In any case, a client can accomplish the genuine advantage of a chatbot just when he can connect with it in a simple manner and it ready to foresee the infection with high level of exactness while simultaneously give all important data being looked for by the patient. Chatbots can either be conventional or sickness explicit in nature. Diabetes is a non-infectious ceaseless human issue. Early forecast of this issue can uncover the deplorable intricacies and help to spare human life. Right now, have first built up a conventional book to-content 'Medibot' – a chatBOT which connects with patients in discussion utilizing propelled Natural Language Understanding (NLU) methods to give customized forecast dependent on the different side effects shared by the patient. The plan is additionally stretched out as a chatBOT to diagonise particular Diabetes type expectation and for proposing prevention measures to be taken. For expectation, there exists various grouping calculations in ML Ways which can be utilized dependent on their exactness. Nonetheless, as opposed to thinking about just one model and trusting this model is the best/most exact indicator we can make, the curiosity right now in Hybrid Algo realizing which is a meta-calculation that joins a bunch of models and midpoints them to create one last model to diminish change (stowing), predisposition (boosting), or improve expectations (stacking). From writing surveys, it is seen that almost no exertion has been placed into utilizing troupe techniques to expand expectation precision. The paper introduces a cutting edge Medibot plan with an undemanding front-end interface for normal man utilizing UI, NLU based content pre-preparing, quantitative execution examination of different AI calculations like Gaussian Naïve Bayes , Entropy Decision tree, Random Forest, K- NN, Support Vector Machines, Logistic and X-Gradient boosting as independent classifiers and joining them all in a dominant part casting a ballot troupe for adjusted outcomes. It is seen that the chatbot can interface consistently with any patient and dependent on the side effects shared, anticipate and rank the most likely ailment precisely utilizing the nonexclusive model and explicitly diabetes dependent on a strong outfit learning model.

scholarly journals A Novel Staphylococcus aureus Vaccine: Iron Surface Determinant B Induces Rapid Antibody Responses in Rhesus Macaques and Specific Increased Survival in a Murine S. aureus Sepsis Model

2006 ◽  
Vol 74 (4) ◽  
pp. 2215-2223 ◽  
Author(s):  
Nelly A. Kuklin ◽  
Desmond J. Clark ◽  
Susan Secore ◽  
James Cook ◽  
Leslie D. Cope ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Immune Responses ◽  
Rhesus Macaques ◽  
Surface Protein ◽  
Antibody Responses ◽  
Iron Surface ◽  
Methicillin Resistant ◽  
Treatment And Prevention ◽  
Antibody Titers ◽  
High Level

ABSTRACT Staphylococcus aureus is a major cause of nosocomial infections worldwide, and the rate of resistance to clinically relevant antibiotics, such as methicillin, is increasing; furthermore, there has been an increase in the number of methicillin-resistant S. aureus community-acquired infections. Effective treatment and prevention strategies are urgently needed. We investigated the potential of the S. aureus surface protein iron surface determinant B (IsdB) as a prophylactic vaccine against S. aureus infection. IsdB is an iron-sequestering protein that is conserved in diverse S. aureus clinical isolates, both methicillin resistant and methicillin sensitive, and it is expressed on the surface of all isolates tested. The vaccine was highly immunogenic in mice when it was formulated with amorphous aluminum hydroxyphosphate sulfate adjuvant, and the resulting antibody responses were associated with reproducible and significant protection in animal models of infection. The specificity of the protective immune responses in mice was demonstrated by using an S. aureus strain deficient for IsdB and HarA, a protein with a high level of identity to IsdB. We also demonstrated that IsdB is highly immunogenic in rhesus macaques, inducing a more-than-fivefold increase in antibody titers after a single immunization. Based on the data presented here, IsdB has excellent prospects for use as a vaccine against S. aureus disease in humans.

scholarly journals THE FEATURES OF OCCUPATIONAL BURNOUT IN CIVIL SERVANTS

2020 ◽  
Vol 4 (14) ◽  
pp. 44-51
Author(s):  
A. Ivanchuk ◽  
A. Kravchenko ◽  
K. Mikhaliev
Keyword(s):  
Emotional Exhaustion ◽  
Civil Servants ◽  
Burnout Syndrome ◽  
Average Score ◽  
Prevention Measures ◽  
Occupational Burnout ◽  
Effective Prevention ◽  
High Prevalence ◽  
High Level ◽  
Mental And Physical Health

Aim: to study the presence and severity of the occupational burnout syndrome components in civil servants. Material and methods. A group of 100 civil servants aged 30 to 60 (mean age 41 ± 7.7 years; 63 (63%) males and 37 (37%) females) were randomly selected and examined. All the enrolled people participated in the regular medical check-up programs, and were free from severe chronic conditions. The Ukrainian version of MBI was used to diagnose the burnout syndrome. Results. In general, medium to high levels of professional burnout for all the burnout syndrome components (emotional exhaustion, depersonalization, reduction of professional achievements) were found in 86 (86,0%) people. Among them, 11 (12,8%) respondents had a high level of each of these three burnout syndrome indicators. Emotional exhaustion was the most frequent condition among the enrolled respondents (totally, 78 (78%) people pointed at medium to high level of emotional exhaustion). Depersonalization was the second most common condition with 65% of respondents (65 people) having its medium to high level. Reduction of professional accomplishment (medium to high level) was less common and registered in 54 (54%) respondents. Females, as compared to males, were more vulnerable to emotional exhaustion, presenting the higher average score ([median, interquartile range] 27 (20-33) vs. 19 (15-25), respectively; p<0,001), and the higher total frequency of medium to high level cases of that burnout syndrome component (89% vs. 72%, respectively; p=0,047), namely due to more frequent latter ones (57% vs. 32%, respectively; p=0,027). Conclusion. The high prevalence of occupational burnout, namely its medium to high severity level, among the civil servants has been established, which indicates the urgency of the problem and the necessity for further research to find the causes, effective prevention measures, and ways to overcome the syndrome and restore the mental and physical health of civil servants.

Family-, Media-, and School-Related Risk Factors of Video Game Addiction

2013 ◽  
Vol 25 (3) ◽  
pp. 118-128 ◽  
Author(s):  
Florian Rehbein ◽  
Dirk Baier
Keyword(s):  
Risk Factors ◽  
Video Game ◽  
Age Groups ◽  
Well Being ◽  
Epidemiological Studies ◽  
Prevention Measures ◽  
School Life ◽  
Video Game Addiction ◽  
Effective Prevention ◽  
Game Addiction

In recent years, a variety of epidemiological studies have provided empirical data on the prevalence of video game addiction (GA) in different age groups. However, few studies investigated the causes of GA and could explain why video game playing as a widespread phenomenon leads to a comparatively small percentage of addicted players. Additionally, the existing longitudinal studies mainly consider psychological trait variables and neglect the possible explanatory value of predictors in socialization regarding media availability, media use, and family and everyday school life. In this paper, the results of a two-wave longitudinal study comprising a sample of students from Grades 4 to 9 (N = 406) are presented. The data show that 15-year-old video game addicts had already exhibited a number of specific risk factors at the age of 10. Students from single-parent families seem to be particularly at risk, as are students with low experienced school well-being and with a weaker social integration in class. The data also indicate that problematic use of video games in childhood increases the risk of GA in adolescence. Male students are especially vulnerable for developing GA. The results of this study are an important contribution to understanding risk factors for GA in adolescents, thereby laying the groundwork for effective prevention measures.

THE SITUATION OF RECOGNITION OF SOME NON-COMMUNICABLE DISEASES AND TREATMENT AND PREVENTIVE BEHAVIORS OF PEOPLE IN THUA THIEN HUE PROVINCE

2019 ◽  
pp. 80-86
Author(s):  
Phuoc Thuoc Doan ◽  
Thi Huong Nguyen ◽  
Thi Thanh Nhan Tran ◽  
Thi Phuong Thao Nguyen ◽  
Thi Thuy Hang Nguyen ◽  
...  
Keyword(s):  
Dietary Habits ◽  
Cross Sectional Study ◽  
Communicable Diseases ◽  
Sectional Study ◽  
Preventive Behaviors ◽  
Cross Sectional ◽  
Non Communicable Diseases ◽  
Treatment And Prevention ◽  
Knowing That ◽  
Appropriate Treatment

Background: Non-communicable diseases seriously affect public health and socio-economic development of the country due to the high number of people suffering from diseases, being disabled and mortal. However, the proportion of people who recognized themselves a suffering from non-communicable diseases such as hypertension, diabetes and dyslipidemia is not high. For cases that their disease situations have been identified, there are not appropriate treatment and preventive behaviors. Objectives: 1) To determine the proportion of 25 - 84 years old peoplewho identified themselves as suffering from hypertension, diabetes and dyslipidemia. 2) To learn treatment and preventive behaviors in the group of people who identified themselves as suffering from diseases. Methods: A cross-sectional study was conducted with a randomly selected sample of 1600 residents in Thua Thien Hue province. Results: The proportion of people knowing that they are suffering from hypertension, diabetes and dyslipidemia was 29.4%; 3.2% and 7.8% respectively. Among them, the proportion of people who did not treat and treated irregularly accounted for 42.7%; 13.7% and 75.2% respectively; the proportion of people who did not change their lifestyles and dietary habits accounted for 50.1%; 5.9% and 56.8% respectively. Conclusions: The proportion of people who identified themselves as suffering from some non-communicable diseases without appropriate treatment and preventive behaviors is alarming. Interventions are needed to help people realize the importance of treatment and prevention effectively. Key words: Non-communicable diseases, hypertension, diabetes, dyslipidemia

scholarly journals Clinical presentation of strokes confined to the insula: a systematic review of literature

2021 ◽  
Author(s):  
Vincenzo Di Stefano ◽  
Maria Vittoria De Angelis ◽  
Chiara Montemitro ◽  
Mirella Russo ◽  
Claudia Carrarini ◽  
...  
Keyword(s):  
Systematic Review ◽  
Clinical Presentation ◽  
Insular Cortex ◽  
Affective Processing ◽  
Appropriate Treatment ◽  
Insula Cortex ◽  
Atypical Presentations ◽  
High Level ◽  
To Receive ◽  
Insular Region

Abstract Background and purpose The insular cortex serves a wide variety of functions in humans, ranging from sensory and affective processing to high-level cognition. Hence, insular dysfunction may result in several different presentations. Ischemic strokes limited to the insular territory are rare and deserve a better characterization, to be quickly recognized and to receive the appropriate treatment (e.g. thrombolysis). Methods We reviewed studies on patients with a first-ever acute stroke restricted to the insula. We searched in the Medline database the keywords “insular stroke” and “insular infarction”, to identify previously published cases. Afterwards, the results were divided depending on the specific insular region affected by the stroke: anterior insular cortex (AIC), posterior insular cortex (PIC) or total insula cortex (TIC). Finally, a review of the clinical correlates associated with each region was performed. Results We identified 25 reports including a total of 49 patients (59.7 ± 15.5 years, 48% male) from systematic review of the literature. The most common clinical phenotypes were motor and somatosensory deficits, dysarthria, aphasia and a vestibular-like syndrome. Atypical presentations were also common and included dysphagia, awareness deficits, gustatory disturbances, dysautonomia, neuropsychiatric or auditory disturbances and headache. Conclusions The clinical presentation of insular strokes is heterogeneous; however, an insular stroke should be suspected when vestibular-like, somatosensory, speech or language disturbances are combined in the same patient. Further studies are needed to improve our understanding of more atypical presentations.

scholarly journals Patient health engagement model: explaining citizens noncompliance and maladaptive behaviors

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
G Graffigna ◽  
S Barello ◽  
L Palamenghi ◽  
M Savarese ◽  
G Castellini
Keyword(s):  
Healthcare Services ◽  
Cross Sectional Study ◽  
Health Prevention ◽  
Prevention Measures ◽  
Cross Sectional ◽  
Health Authorities ◽  
Patient Health ◽  
Public Health Authorities ◽  
High Level ◽  
Restrictive Measures

Abstract Background At the end of February 2020 a new case was diagnosed with COVID-19 in north Italy, suddenly followed by new cases. Italian health authorities decided to enforce restrictive measures. Northern areas of Italy were identified as “red areas” to slow down the epidemic and its impact on the healthcare system. From this perspective, the COVID-19 epidemic in Italy constitutes a testing ground for the assessment of the ability of consumers to cope with this health risk. Methods A cross-sectional study on a representative sample of 1000 Italian citizens was conducted over the period 27 February- 5 March exploring the following hypotheses: 1) less engaged individuals are more concerned for the health emergency and feel more vulnerable; 2) less engaged have higher probability to develop negative attitudes and dysfunctional behaviors. Results only the 16% the interviewees presented a high level of engagement. Lower levels of engagement were measured in the southern parts of Italy (not yet touched by the epidemics at the time of data collection). People with lowers levels of engagement reported higher fears for the contagion and sense of vulnerability. Furthermore, they showed the lower levels of trust in the Public Health Authorities, in medical research and in vaccines. Finally, they appeared more dismissive in their preventive behaviors and more disorganized in the fruition of the healthcare services. Conclusions A psychological analysis of processes of attitudinal and role change in the direction of becoming more engaged in health prevention is worthy in order to forecast potential dysfunctional reactions to restrictive health prevention measures and to orient personalized education initiatives to consumers with different level of engagement. Key messages Profiling based on the levels of health engagement is important in order to plan more effective healthcare measures during epidemics. Targeted educational initiatives should take into account citizens' engagement profiles.

Adherence to Primary Prevention and Skin Self-Examination Practices by Spanish Melanoma Patients

Dermatology ◽  
2021 ◽  
pp. 1-7
Author(s):  
Irene Torrecilla-Martínez ◽  
Esperanza Manrique-Silva ◽  
Victor Traves ◽  
Celia Requena ◽  
Eduardo Nagore
Keyword(s):  
Primary Prevention ◽  
Cutaneous Melanoma ◽  
Public Health Problem ◽  
Global Public Health ◽  
Prevention Measures ◽  
Online Questionnaire ◽  
Cross Sectional ◽  
History Of ◽  
High Level ◽  
Self Examination

<b><i>Background:</i></b> The incidence of cutaneous melanoma, an important global public health problem, has been increasing over the last several decades. <b><i>Objectives:</i></b> In order to decrease melanoma-related mortality, ways to communicate and implement the correct methods for conducting primary and secondary prevention measures (such as early detection via self-examination) should be investigated. <b><i>Materials and Methods:</i></b> An observational, cross-sectional, retrospective study consisting of 409 patients diagnosed with cutaneous melanoma was conducted. An online questionnaire was created to evaluate knowledge levels, attitudes, and adherence to primary preventive measures and to skin self-examination practices. <b><i>Results:</i></b> The results revealed that even when 43% of the patients perform cutaneous self-examinations, only half of them fully followed the recommendations. Patients aged &#x3c;45 years, female, with a I–II phototype, with an intermediate/high level of education, and with a history of NMSC were more likely to have an adequate degree of knowledge. Moreover, patients aged &#x3c;45 years and with an adequate degree of knowledge more frequently showed an adequate adherence to the primary prevention measures. Finally, patients aged 45–60 years and with an adequate degree of knowledge presented a good adherence to the self-skin examination measures. <b><i>Limitations:</i></b> Possible limitations of this study were memory bias through the influence of age within the study population, and bias due to a greater proportion of subjects with a high education level. <b><i>Conclusion:</i></b> Within the population of patients with melanoma, a high percentage of patients do not rigorously follow the recommended prevention measures. Our study highlights the need to implement awareness in this population to improve the prevention of cutaneous cancer.

scholarly journals Cystamine attenuated behavioral deficiency via increasing the expression of BDNF and activating PI3K/Akt signaling in 2,5-hexanedione intoxicated rats

2017 ◽  
Vol 6 (2) ◽  
pp. 199-204 ◽  
Author(s):  
Shuo Wang ◽  
Xianjie Li ◽  
Ming Li ◽  
Lulu Jiang ◽  
Hua Yuan ◽  
...  
Keyword(s):  
Public Health ◽  
Organic Solvent ◽  
Health Problem ◽  
Public Health Problem ◽  
Akt Signaling ◽  
Prevention Measures ◽  
Effective Prevention

Organic solvent-induced neurodegeneration is a severe public health problem which has no effective prevention measures yet.

scholarly journals Prevalence of Chlorhexidine-Resistant Methicillin-Resistant Staphylococcus aureus following Prolonged Exposure

2014 ◽  
Vol 58 (8) ◽  
pp. 4404-4410 ◽  
Author(s):  
Carey D. Schlett ◽  
Eugene V. Millar ◽  
Katrina B. Crawford ◽  
Tianyuan Cui ◽  
Jeffrey B. Lanier ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Molecular Analysis ◽  
Prolonged Exposure ◽  
Controlled Trial ◽  
Epidemiological Data ◽  
Methicillin Resistant ◽  
Content Type ◽  
Mupirocin Resistance ◽  
High Level ◽  
Study Participants

ABSTRACTChlorhexidine has been increasingly utilized in outpatient settings to control methicillin-resistantStaphylococcus aureus(MRSA) outbreaks and as a component of programs for MRSA decolonization and prevention of skin and soft-tissue infections (SSTIs). The objective of this study was to determine the prevalence of chlorhexidine resistance in clinical and colonizing MRSA isolates obtained in the context of a community-based cluster-randomized controlled trial for SSTI prevention, during which 10,030 soldiers were issued chlorhexidine for body washing. We obtained epidemiological data on study participants and performed molecular analysis of MRSA isolates, including PCR assays for determinants of chlorhexidine resistance and high-level mupirocin resistance and pulsed-field gel electrophoresis (PFGE). During the study period, May 2010 to January 2012, we identified 720 MRSA isolates, of which 615 (85.4%) were available for molecular analysis, i.e., 341 clinical and 274 colonizing isolates. Overall, only 10 (1.6%) of 615 isolates were chlorhexidine resistant, including three from the chlorhexidine group and seven from nonchlorhexidine groups (P> 0.99). Five (1.5%) of the 341 clinical isolates and five (1.8%) of the 274 colonizing isolates harbored chlorhexidine resistance genes, and four (40%) of the 10 possessed genetic determinants for mupirocin resistance. All chlorhexidine-resistant isolates were USA300. The overall prevalence of chlorhexidine resistance in MRSA isolates obtained from our study participants was low. We found no association between extended chlorhexidine use and the prevalence of chlorhexidine-resistant MRSA isolates; however, continued surveillance is warranted, as this agent continues to be utilized for infection control and prevention efforts.

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