Analysis of sero-epidemiological characteristics of varicella in healthy children in Jiangsu Province, China

Abstract Background: Compared to influenza virus and respiratory syncytial virus, common human coronaviruses (HCoVs) are relatively understudied due to the mild nature of HCoV infection. Given the lack of local epidemiology data on common HCoVs in Korea, we aimed to describe epidemiological characteristics of common HCoVs. Methods: Respiratory viral test results from more than 67,000 respiratory samples from the two data sources, Korea Influenza and Respiratory Viruses Surveillance System (KINRESS, N=58,253) and Seoul National University Children’s Hospital (SNUCH, N=9,589) were analyzed from January 2015 to December 2019. Viral detection was done by the multiplex RT-PCR. Demographics and clinical diagnosis were collected for previously healthy children tested positive for HCoVs in SNUCH. Results: Of the 67,842 samples tested, 1 or more respiratory viruses were detected from 35,459 (52.2%) samples and 2,854 (4.2%) samples were positive for HCoVs (OC43 2.1%, NL63 1.7%, 229E 0.4%). All 3 types were co-circulated during winter months (November to February) with some variation by type. HCoV-OC43 was most prevalent, peaking every winter. HCoV-NL63 circulated with alternate peaks occurring between January-March and November-February. Meanwhile, HCoV-229E had smaller peaks every other winter in 2015/2016 and 2017/2018. From the national surveillance data, HCoV infection was most prevalent among 0 to 1 year old children and older adults aged over 70 years. 18.2% of the HCoV-positive samples were co-detected with other respiratory viruses, with the highest co-detection rate (33.7%) in children 0 to 1 year of age and the lowest co-detection rate (3.6%) in adults ≥70 years old. Upper respiratory tract infection was the most common (60.0%) clinical diagnosis of the 135 previously healthy children. Croup accounted for 17.0% of NL63-positive childrenConclusion: This study described the epidemiological characteristics of 3 types of common HCoVs (OC43, NL63, 229E) in Korea; the highest prevalence of OC43, concurrent circulation during winter, and age difference in HCoV infection and co-detection rate with other respiratory virus. It may be informative to monitor any changes in the epidemiology of common HCoVs as the COVID-19 pandemic continues.

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Self-poisoning with pesticides in Jiangsu Province, China: a cross-sectional study on 24,602 subjects

BMC Psychiatry ◽

10.1186/s12888-020-02882-9 ◽

2020 ◽

Vol 20 (1) ◽

Author(s):

Boshen Wang ◽

Lei Han ◽

Jinbo Wen ◽

Juan Zhang ◽

Baoli Zhu

Keyword(s):

Rural Areas ◽

The Elderly ◽

Cross Sectional Study ◽

Jiangsu Province ◽

Related Factors ◽

Cross Sectional ◽

Pesticide Management ◽

Routine Surveillance ◽

Control And Prevention ◽

Epidemiological Characteristics

Abstract Background With an estimated > 800,000 suicide-related deaths and potentially several attempts for each death in the world. The purpose of this study was to determine the epidemiological characteristics of self-poisoning with pesticides within the Jiangsu province in China. Methods Suicide rate was calculated the Routine Surveillance System by Jiangsu Provincial Center for Disease Control and Prevention, stratified by gender, age and region, combined with socioeconomic and agriculture-related factors to investigate trends in suicide over the study period. A logistic regression model was used to investigate the associations between pesticide types and pesticide-related deaths. Results In recent years, Jiangsu Province has witnessed a decrease in pesticide self-poisoning cases and consequent deaths. Among all suicides by deliberate ingestion of pesticides, the proportion of cases were mainly in the age 40, accounting for 3.43% of all cases with pesticide suicide. The proportion of suicide due to pesticide poisoning in females was markedly higher than that in males (p < 0.001). Suicide using organophosphate and carbamate insecticides was most common, with 10,303 reported cases accounting for 42.02% of all suicides. Conclusions For national responses to be effective, the characteristics of pesticide suicides should be comprehensively investigated for the formulation of corresponding prevention strategies. At present, more pesticide suicide prevention policies for the elderly people and women should be implemented, and stronger pesticide management policies should be implemented for rural areas.

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COVID-19: epidemiology and preventive measures in Jiangsu province, China

10.21203/rs.3.rs-25763/v1 ◽

2020 ◽

Author(s):

Yi Chen ◽

JiaShu Liu ◽

ChangRui Yang ◽

Zi-sheng Ai ◽

AiHong Zhang

Keyword(s):

Preventive Measures ◽

Jiangsu Province ◽

Prevention Measures ◽

Cure Rate ◽

The People ◽

Improve Cure Rate ◽

Imported Cases ◽

Community Transmission ◽

Novel Coronavirus ◽

Epidemiological Characteristics

Abstract Background: To investigate the epidemiological features of coronavirus disease 2019(COVID-19) and the prevention measures in Jiangsu Province. Methods: Information of all novel coronavirus pneumonia conﬁrmed cases in Jiangsu was collected from the oﬃcial website of Jiangsu Commission of Health. All data were entered into Excel and Python3 for statistical analysis. Epidemiological characteristics of novel coronavirus pneumonia conﬁrmed cases from January 10, 2020 to March 18 in Jiangsu province were retrospectively analyzed. Meanwhile, the preventive measures of Jiangsu Commission of Health and the people’s Government of Jiangsu Province were also analyzed. Results: 631 COVID-19 cases were diagnosed in Jiangsu Province, covering 13 cities in Jiangsu. Before February 1, the conﬁrmed cases were mainly imported cases, and after February 1, community transmission cases became main part of conﬁrmed cases. There were more male patients than females, and most patients were in the group of 30-70 years old, 49 patients (7.8%) with mild symptom and 572 patients (90.6%) with common type accounted for the majority. The cumulative mortality rate was 0% and the cure rate was 100%. Reasonable treatments, timely and eﬀective preventive measures were taken to eﬀectively improve cure rate and to prevent the spread of the epidemic, all measures ensure the health and life safety of the people. Conclusion: The preventive measures in Jiangsu Province were timely and eﬀective, the epidemic situation in Jiangsu Province had been well controlled.

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Self-poisoning with pesticides in Jiangsu Province, China: a cross-sectional study on 24,602 subjects

10.21203/rs.3.rs-39759/v2 ◽

2020 ◽

Author(s):

Boshen Wang ◽

Lei Han ◽

Jinbo Wen ◽

Juan Zhang ◽

Baoli Zhu

Keyword(s):

Rural Areas ◽

The Elderly ◽

Cross Sectional Study ◽

Jiangsu Province ◽

Related Factors ◽

Cross Sectional ◽

Pesticide Management ◽

Routine Surveillance ◽

Control And Prevention ◽

Epidemiological Characteristics

Abstract Background: With an estimated >800,000 suicide-related deaths and potentially several attempts for each death in the world. The purpose of this study was to determine the epidemiological characteristics of self-poisoning with pesticides within the Jiangsu province in China. Methods: Suicide rate was calculated the Routine Surveillance System by Jiangsu Provincial Center for Disease Control and Prevention, stratified by gender, age and region, combined with socioeconomic and agriculture-related factors to investigate trends in suicide over the study period. A logistic regression model was used to investigate the associations between pesticide types and pesticide-related deaths. Results: In recent years, Jiangsu Province has witnessed a decrease in pesticide self-poisoning cases and consequent deaths. Among all suicides by deliberate ingestion of pesticides, the proportion of cases were mainly in the age 40, accounting for 3.43% of all cases with pesticide suicide. The proportion of suicide due to pesticide poisoning in females was markedly higher than that in males ( p <0.001). Suicide using organophosphate and carbamate insecticides was most common, with 10,303 reported cases accounting for 42.02% of all suicides. Conclusions: For national responses to be effective, the characteristics of pesticide suicides should be comprehensively investigated for the formulation of corresponding prevention strategies. At present, more pesticide suicide prevention policies for the elderly people and women should be implemented, and stronger pesticide management policies should be implemented for rural areas.

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Hepatitis E in 24 Chinese Cities, 2008–2018: A New Analysis Method for the Disease's Occupational Characteristics

Frontiers in Public Health ◽

10.3389/fpubh.2021.720953 ◽

2021 ◽

Vol 9 ◽

Author(s):

Shanshan Yu ◽

Jia Rui ◽

Xiaoqing Cheng ◽

Zeyu Zhao ◽

Chan Liu ◽

...

Keyword(s):

Cluster Analysis ◽

Eastern China ◽

Hepatitis E ◽

Jiangsu Province ◽

Jilin Province ◽

New Method ◽

The South ◽

Xiamen City ◽

Occupational Composition ◽

Epidemiological Characteristics

Background: The disease burden of hepatitis E remains high. We used a new method (richness, diversity, evenness, and similarity analyses) to classify cities according to the occupational classification of hepatitis E patients across regions in China and compared the results of cluster analysis.Methods: Data on reported hepatitis E cases from 2008 to 2018 were collected from 24 cities (9 in Jilin Province, 13 in Jiangsu Province, Xiamen City, and Chuxiong Yi Autonomous Prefecture). Traditional statistical methods were used to describe the epidemiological characteristics of hepatitis E patients, while the new method and cluster analysis were used to classify the cities by analyzing the occupational composition across regions.Results: The prevalence of hepatitis E in eastern China (Jiangsu Province) was similar to that in the south (Xiamen City) and southwest of China (Chuxiong Yi Autonomous Prefecture), but higher than that in the north (Jilin Province). The age of hepatitis E patients was concentrated between 41 and 60 years, and the sex ratio ranged from 1:1.6 to 1:3.4. Farming was the most highly prevalent occupation; other sub-prevalent occupations included retirement, housework and unemployment. The incidence of occupations among migrant workers, medical staff, teachers, and students was moderate. There were several occupational types with few or no records, such as catering industry, caregivers and babysitters, diaspora children, childcare, herders, and fishing (boat) people. The occupational similarity of hepatitis E was high among economically developed cities, such as Nanjing, Wuxi, Baicheng, and Xiamen, while the similarity was small among cities with large economic disparities, such as Nanjing and Chuxiong Yi Autonomous Prefecture. A comparison of the classification results revealed more similarities and some differences when using these two methods.Conclusion: In China, the factors with the greatest influence on the prevalence of hepatitis E are living in the south, farming as an occupation, being middle-aged or elderly, and being male. The 24 cities we studied were highly diverse and moderately similar in terms of the occupational distribution of patients with hepatitis E. We confirmed the validity of the new method on in classifying cities according to their occupational composition by comparing it with the clustering method.

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Self-poisoning with pesticides in Jiangsu Province, China: a cross-sectional study on 24,602 subjects

10.21203/rs.3.rs-39759/v1 ◽

2020 ◽

Author(s):

Boshen Wang ◽

Lei Han ◽

Jinbo Wen ◽

Juan Zhang ◽

Baoli Zhu

Keyword(s):

Cross Sectional Study ◽

Jiangsu Province ◽

Sectional Study ◽

Prevention Strategies ◽

Cross Sectional ◽

Carbamate Insecticides ◽

Routine Surveillance ◽

Control And Prevention ◽

Epidemiological Characteristics ◽

Provincial Center

Abstract Background With an estimated > 800,000 suicide-related deaths and potentially several attempts for each death in the world. The purpose of this study was to determine the epidemiological characteristics of self-poisoning with pesticides within the Jiangsu province in China. Methods We evaluated the incidence of pesticide self-poisoning using the Routine Surveillance System by Jiangsu Provincial Center for Disease Control and Prevention. Results In recent years, Jiangsu Province has witnessed a decrease in pesticide self-poisoning cases and consequent deaths. Among all suicides by deliberate ingestion of pesticides, the proportion of cases were mainly in the age 40, accounting for 3.43% of all cases with pesticide suicide. The proportion of suicide due to pesticide poisoning in females was markedly higher than that in males (p < 0.001). Moreover, higher numbers of self-poisoning cases and deaths were reported in the farming season. Suicide using organophosphate and carbamate insecticides was most common, with 10,303 reported cases accounting for 42.02% of all suicides. Conclusions For national responses to be effective, the characteristics of pesticide suicides should be comprehensively investigated for the formulation of corresponding prevention strategies. Restriction of access to means plays an important role in suicide prevention, particularly in impulsive suicide cases. Implementation of these prevention strategies should result in an ongoing decline in the proportion of suicide.

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Publisher Correction: Epidemiological characteristics of pesticide poisoning in Jiangsu Province, China, from 2007 to 2016

Scientific Reports ◽

10.1038/s41598-020-58044-0 ◽

2020 ◽

Vol 10 (1) ◽

Author(s):

Ning Wang ◽

Qingtao Jiang ◽

Lei Han ◽

Hengdong Zhang ◽

Baoli Zhu ◽

...

Keyword(s):

Jiangsu Province ◽

Pesticide Poisoning ◽

Epidemiological Characteristics

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Study of Risk Factors for Total Attack Rate and Transmission Dynamics of Norovirus Outbreaks, Jiangsu Province, China, From 2012 to 2018

Frontiers in Medicine ◽

10.3389/fmed.2021.786096 ◽

2022 ◽

Vol 8 ◽

Author(s):

Jing Ai ◽

Yuanzhao Zhu ◽

Jianguang Fu ◽

Xiaoqing Cheng ◽

Xuefeng Zhang ◽

...

Keyword(s):

Risk Factors ◽

Statistical Analysis ◽

Attack Rate ◽

Primary Schools ◽

Prevention And Control ◽

Jiangsu Province ◽

Factors Associated ◽

The Mean ◽

And Control ◽

Epidemiological Characteristics

Objective: To describe the epidemiological characteristics of norovirus outbreaks in Jiangsu Province, utilize the total attack rate (TAR) and transmissibility (Runc) as the measurement indicators of the outbreak, and a statistical difference in risk factors associated with TAR and transmissibility was compared. Ultimately, this study aimed to provide scientific suggestions to develop the most appropriate prevention and control measures.Method: We collected epidemiological data from investigation reports of all norovirus outbreaks in Jiangsu Province from 2012 to 2018 and performed epidemiological descriptions, sequenced the genes of the positive specimens collected that were eligible for sequencing, created a database and calculated the TAR, constructed SEIAR and SEIARW transmission dynamic models to calculate Runc, and performed statistical analyses of risk factors associated with the TAR and Runc.Results: We collected a total of 206 reported outbreaks, of which 145 could be used to calculate transmissibility. The mean TAR in was 2.6% and the mean Runc was 12.2. The epidemiological characteristics of norovirus outbreaks showed an overall increasing trend in the number of norovirus outbreaks from 2012 to 2018; more outbreaks in southern Jiangsu than northern Jiangsu; more outbreaks in urban areas than in rural areas; outbreaks occurred mostly in autumn and winter. Most of the sites where outbreaks occurred were schools, especially primary schools. Interpersonal transmission accounted for the majority. Analysis of the genotypes of noroviruses revealed that the major genotypes of the viruses changed every 3 years, with the GII.2 [P16] type of norovirus dominating from 2016 to 2018. Statistical analysis of TAR associated with risk factors found statistical differences in all risk factors, including time (year, month, season), location (geographic location, type of settlement, type of premises), population (total number of susceptible people at the outbreak site), transmission route, and genotype (P < 0.05). Statistical analysis of transmissibility associated with risk factors revealed that only transmissibility was statistically different between sites.Conclusions: The number of norovirus outbreaks in Jiangsu Province continues to increase during the follow-up period. Our findings highlight the impact of different factors on norovirus outbreaks and identify the key points of prevention and control in Jiangsu Province.

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Self-poisoning with pesticides in Jiangsu Province, China: a cross-sectional study on 24,602 subjects

10.21203/rs.3.rs-39759/v4 ◽

2020 ◽

Author(s):

Boshen Wang ◽

Lei Han ◽

Jinbo Wen ◽

Juan Zhang ◽

Baoli Zhu

Keyword(s):

Rural Areas ◽

The Elderly ◽

Cross Sectional Study ◽

Jiangsu Province ◽

Related Factors ◽

Cross Sectional ◽

Pesticide Management ◽

Routine Surveillance ◽

Control And Prevention ◽

Epidemiological Characteristics

Abstract Background: With an estimated >800,000 suicide-related deaths and potentially several attempts for each death in the world. The purpose of this study was to determine the epidemiological characteristics of self-poisoning with pesticides within the Jiangsu province in China. Methods: Suicide rate was calculated the Routine Surveillance System by Jiangsu Provincial Center for Disease Control and Prevention, stratified by gender, age and region, combined with socioeconomic and agriculture-related factors to investigate trends in suicide over the study period. A logistic regression model was used to investigate the associations between pesticide types and pesticide-related deaths.Results: In recent years, Jiangsu Province has witnessed a decrease in pesticide self-poisoning cases and consequent deaths. Among all suicides by deliberate ingestion of pesticides, the proportion of cases were mainly in the age 40, accounting for 3.43% of all cases with pesticide suicide. The proportion of suicide due to pesticide poisoning in females was markedly higher than that in males (p<0.001). Suicide using organophosphate and carbamate insecticides was most common, with 10,303 reported cases accounting for 42.02% of all suicides. Conclusions: For national responses to be effective, the characteristics of pesticide suicides should be comprehensively investigated for the formulation of corresponding prevention strategies. At present, more pesticide suicide prevention policies for the elderly people and women should be implemented, and stronger pesticide management policies should be implemented for rural areas.

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