scholarly journals Prevalence of SARS-CoV-2 antibodies in hemodialysis patients in Senegal: a multicenter cross-sectional study

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Sidy Mohamed Seck ◽  
Moustapha Mbow ◽  
Yaya Kane ◽  
Mouhamadou Moustapha Cisse ◽  
Gnagna Faye ◽  
...  
Keyword(s):  
Clinical Symptoms ◽  
Statistical Tests ◽  
Risk Groups ◽  
Cross Sectional Study ◽  
Hemodialysis Patients ◽  
Cross Sectional Survey ◽  
Density Region ◽  
Cross Sectional ◽  
Seroprevalence Data ◽  
Wide Variability

Abstract Background Hemodialysis patients are among high-risk groups for COVID-19. Africa is the continent with the lowest number of cases in the general population but we have little information about the disease burden in dialysis patients. Objectives This study aimed to describe the seroprevalence of SARS-CoV-2 antibodies in the hemodialysis population of Senegal. Patients and methods We conducted a multicenter cross-sectional survey, between June and September 2020 involving 10 public dialysis units randomly selected in eight regions of Senegal. After seeking their consent, we included 303 patients aged ≥ 18 years and hemodialysis for ≥ 3 months. Clinical symptoms and biological parameters were collected from medical records. Patients’ blood samples were tested with Abbott SARS-CoV-2 Ig G assay using an Architect system. Statistical tests were performed with STATA 12.0. Results Seroprevalence of SARS-CoV-2 antibodies was 21.1% (95% CI = 16.7–26.1%). We noticed a wide variability in SARS-CoV-2 seroprevalence between regions ranging from 5.6 to 51.7%. Among the 38 patients who underwent nasal swab testing, only six had a PCR-confirmed infection and all of them did seroconvert. Suggestive clinical symptoms were reported by 28.1% of seropositive patients and the majority of them presented asymptomatic disease. After multivariate analysis, a previous contact with a confirmed case and living in a high population density region were associated with the presence of SARS-CoV-2 antibodies. Conclusion This study presents to our knowledge the first seroprevalence data in African hemodialysis patients. Compared to data from other continents, we found a higher proportion of patients with SARS-CoV-2 antibodies but a lower lethality rate.

scholarly journals Prevalence of SARS-CoV-2 Antibodies in Hemodialysis Patients in Senegal: A Multicenter Cross-Sectional Study

2021 ◽  
Author(s):  
Sidy Mohamed Seck ◽  
Moustapha Mbow ◽  
Yaya Kane ◽  
Mouhamadou Moustapha Cisse ◽  
Gnagna Faye ◽  
...  
Keyword(s):  
Clinical Symptoms ◽  
Statistical Tests ◽  
Risk Groups ◽  
Cross Sectional Study ◽  
Hemodialysis Patients ◽  
Cross Sectional Survey ◽  
Density Region ◽  
Cross Sectional ◽  
Seroprevalence Data ◽  
Wide Variability

Abstract BackgroundHemodialysis patients are among high-risk groups for COVID-19. Africa is the continent with the lowest number of cases in the general population but we have little information about the disease burden in dialysis patients. Objectives:This study aimed to describe the seroprevalence of SARS-CoV-2 antibodies in the hemodialysis population of Senegal.Patients and methodsWe conducted a multicenter cross-sectional survey, between June and September 2020 involving 10 public dialysis units randomly selected in eight regions of Senegal. After seeking their consent, we included 303 patients aged ≥18 years and hemodialysis for ≥3 months. Clinical symptoms and biological parameters were collected from medical records. Patients’ blood samples were tested with Abbott SARS-CoV-2 Ig G assay using an Architect system. Statistical tests were performed with STATA 20.ResultsSeroprevalence of SARS-CoV-2 antibodies was 21.1% (95% CI= 16.7%-26.1%). We noticed a wide variability in SARS-CoV-2 seroprevalence between regions ranging from 5.6% to 51.7%. Among the 38 patients who underwent nasal swab testing, only six patients had a PCR-confirmed infection and all of them did seroconvert. Suggestive clinical symptoms were reported by 28.1% of seropositive patients and the majority of them presented asymptomatic disease. After multivariate analysis, a previous contact with a confirmed case and living in a high population density region were associated with the presence of SARS-CoV-2 antibodies.ConclusionThis study presents to our knowledge the first seroprevalence data in African hemodialysis patients. Compared to data from other continents, we found a higher proportion of patients with SARS-CoV-2 antibodies but a lower lethality rate.

scholarly journals Population's Knowledge About COVID-19: A Cross-Sectional Web-Based Study in Brazil (Preprint)

2020 ◽  
Author(s):  
Vinícius Henrique Almeida Guimarães ◽  
Maisa De Oliveira Leandro ◽  
Carolina Cassiano ◽  
Anna Laura Piantino Marques ◽  
Clara Motta ◽  
...  
Keyword(s):  
Social Network ◽  
Drug Repositioning ◽  
Statistical Tests ◽  
Risk Groups ◽  
Cross Sectional Study ◽  
Basic Knowledge ◽  
Online Questionnaire ◽  
Questionnaire Response ◽  
Cross Sectional ◽  
Social Distancing

BACKGROUND Coronavirus disease 2019 (COVID-19) is a highly transmissible illness caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The disease has affected more than 200 countries and the measures that have been implemented to combat its spread, as there is still no vaccine or definitive medication, have been based on supportive interventions and drug repositioning. Brazil, the largest country in South America, has had more than 140,000 recorded deaths and is one of the most affected countries. Despite the extensive quantity of scientifically recognized information, there are still conflicting discussions on how best to face the disease and the virus, especially with regard to social distancing, preventive methods, and the use of medications. OBJECTIVE Thus, the main purpose of this work was to evaluate the Brazilian population’s basic knowledge about COVID-19 to demonstrate how Brazilians are managing to identify only scientifically proven information. METHODS A cross-sectional study design was used. An original online questionnaire survey was administered from June 16 to August 21, 2020 across all five different geopolitical regions of the country (i.e., the North, Northeast, Center-West, Southeast, and South). The questionnaire was comprised of questions about basic aspects of COVID-19, such as the related symptoms, conduct that should be followed when suspected of infection, risk groups, prevention, transmission, and social distancing. The wrong questionnaire response alternatives were taken from the fake news combat website of Brazilian Ministry of Health. Participants (aged ≥18 years) were recruited through social network platforms including Facebook, WhatsApp, and Twitter. The mean distribution, frequencies and (dis) similarity between the responses for the different variables of the study were evaluated. Significance levels in all statistical tests were less than 0.05. RESULTS A total of 4,180 valid responses representative of all the states and regions of Brazil were recorded. Most respondents had good knowledge about COVID-19, getting an average of 86.59% of the total score, with regard to the basic aspects of the disease. Region, educational level, age, sex, and social condition had a significant association (p < 0.0001) with knowledge about the disease, which meant that women, the young, those with higher educational levels, non-recipients of social assistance, and more economically and socially developed regions had more correct answers. CONCLUSIONS Overall, Brazilians with social media access can be said to have a good level of basic knowledge about COVID-19, but with differences depending on the analyzed subgroup. Due to the limitation of the platform used in carrying out the study, care should be taken when generalizing the study findings to populations unschooled or who are not used to accessing social network platforms. CLINICALTRIAL

scholarly journals Knowledge, Perception, Attitude, Practice, and Barriers towards COVID-19 Infection among Saudi Residents in the Period of Rapid Outbreak of the Disease: A Cross Sectional Survey

2021 ◽  
pp. 7-21
Author(s):  
Md Salahuddin Ansari ◽  
Faisal Al-Otaibi
Keyword(s):  
Global Economy ◽  
Online Survey ◽  
Clinical Symptoms ◽  
Cross Sectional Study ◽  
Cross Sectional Survey ◽  
Chi Square ◽  
Cross Sectional ◽  
Behavioral Parameters ◽  
Chi Square Test ◽  
Appropriate Practices

The adherences to protective actions are subjective to knowledge, perception, attitude, practice and barriers towards COVID-19 by Saudi residents. The self-design questionnaires were used as a cross-sectional online survey for assessed their social and behavioral parameters during the agonizing time. The cross-sectional study used data collected via an online self-reported questionnaire from 2216 Saudi residents. SPSS software and chi-square test were applied to analyze and categorize significant differences among sectional variables of the parameters. More than 95% of responders were well aware about the main clinical symptoms of COVID-19 infection and had sufficient knowledge about the protocols of five steps to stop the spread of coronavirus. Apositive perception towards COVID-19 was observed, about 55% participants strongly agreed that the coronavirus outbreak could impact the global economy and infection could be successfully controlled by imposing lockdown and by staying at home. The majority of respondents had good practices regarding COVID-19 infection. A high percentage of participants favored wearing masks, cleaning hands and frequently using hand sanitizer. A large number of participant (83.2%; n=1844) agreed that misinformation and rumors are spreading more quickly than the current outbreak of the new coronavirus. The findings suggested that Saudi residents are possessed good knowledge, optimistic attitudes, and appropriate practices towards COVID-19 during the rapid rise of the COVID-19 outbreak. Hopefully, under the combined efforts of WHO, Ministry of Health, Saudi Arabia, all Saudi residents surely will win the battle against COVID-19 very soon.

scholarly journals Prevalence and risk factors for SARS-CoV-2 infection in children with and without symptoms seeking care in Managua, Nicaragua: results of a cross-sectional survey

BMJ Open ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. e051836
Author(s):  
Jorge A Huete-Pérez ◽  
Kacey C Ernst ◽  
Cristiana Cabezas-Robelo ◽  
Lucia Páiz-Medina ◽  
Sheyla Silva ◽  
...  
Keyword(s):  
Risk Factors ◽  
Clinical Symptoms ◽  
Age Distribution ◽  
Epidemiological Data ◽  
Cross Sectional Study ◽  
Comorbid Condition ◽  
Prevention Measures ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
High Prevalence

ObjectiveThis study aimed to capture key epidemiological data on SARS-CoV-2 infection in Nicaraguan children (≤18 years) seeking medical care, between 6 October and 16 November 2020.DesignIn this cross-sectional study, 418 children were recruited: 319 with symptoms characteristic of COVID-19 and 99 with no symptoms of illness. Children were tested for SARS-CoV-2 RNA using loop-mediated isothermal amplification. A questionnaire was employed to identify symptoms, risk factors, comorbidities and COVID-19 prevention measures.SettingResearch was carried out in four hospitals and two clinics in Managua, Nicaragua, where schools and businesses remained open throughout the COVID-19 pandemic.ParticipantsChildren were enrolled into a possible COVID-19 group if presenting with clinical symptoms. A comparison group included children lacking any COVID-19 symptoms attending routine check-ups or seeking care for issues unrelated to COVID-19.ResultsA high prevalence (43%) of SARS-CoV-2 infection was found, which was relatively equivalent in symptomatic and non-symptomatic children. Age distribution was similar between symptomatic and non-symptomatic children testing positive for SARS-CoV-2. Symptomatic children who tested positive for SARS-CoV-2 were 2.7 times more likely to have diarrhoea (26.7% in positive vs 12.0% in negative; OR=2.7 (95% CI 1.5 to 4.8), p=0.001) and were 2.0 times more likely to have myalgia (17.8% in positive vs 9.8% in negative; OR=2.0 (95% CI 1.0 to 3.8), p=0.04). Children with COVID-19 symptoms, who tested positive for SARS-CoV-2, were more likely to be under age 5 years and to have a pre-existing comorbid condition than children who tested positive but did not have symptoms.ConclusionsThis is the first paediatric study to provide laboratory-confirmed data on SARS-CoV-2 infection in Nicaragua, crucial for paediatric health services planning and a successful COVID-19 response. The high prevalence of the virus suggests widespread and sustained community transmission, underscoring the urgent need for robust data on the true extent of SARS-CoV-2 infection throughout Nicaragua.

scholarly journals The Impact of COVID-19 on Plastic Surgery Training in the United Kingdom, Canada and Australia—A Cross-Sectional Study

2021 ◽  
Author(s):  
Curtis R Budden ◽  
Francesca Rannard ◽  
Joanna Mennie ◽  
Neil Bulstrode
Keyword(s):  
Plastic Surgery ◽  
Statistical Tests ◽  
Cross Sectional Study ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
The United Kingdom ◽  
Surgical Trainees ◽  
Significant Difference ◽  
The Uk ◽  
The Impact

Abstract Background Surgical trainees worldwide have been thrust into a period of uncertainty, with respect to the implications COVID-19 pandemic will have on their roles, training, and future career prospects. It is currently unclear how plastic surgery trainees are being affected by COVID-19. This study examined the experience of plastic surgery trainees in Canada, the UK, and Australia to determine trainee roles during the early COVID-19 emergency response and how training changed during this time. Methods A cross-sectional survey-based study was designed for plastic surgery trainees in the UK, Canada and Australia. In total, 110 trainees responded to the survey. Statistical tests were conducted to determine differences in responses, based on year of training and country of residence. Results In total, 9.7% (10/103) of respondents reported being deployed to cover another service. There was a significant difference between redeployment based on country (p = 0.001). Within the UK group, 28.9% of respondents were redeployed. For trainees not deployed, 95.5% (85/89) reported that there has been a reduction in operative volume. Ninety-seven (94.1%) respondents reported that there were ongoing teaching activities offered by their program. The majority of trainees (66.4%) were concerned about their training. There was a significant difference between overall concern and country (p < 0.05). Conclusion In these unprecedented times, training programs in plastic surgery should be aware of the major impact that COVID-19 has had on trainees and will have on their training. The majority of plastic surgery trainees have experienced a reduction in surgical exposure but have maintained some form of regular teaching.

scholarly journals Knowledge, Attitude, and Self-Reported Practice Toward Measures for Prevention of the Spread of COVID-19 Among Ugandans: A Nationwide Online Cross-Sectional Survey

2020 ◽  
Vol 8 ◽  
Author(s):  
Robinson Ssebuufu ◽  
Franck Katembo Sikakulya ◽  
Simon Binezero Mambo ◽  
Lucien Wasingya ◽  
Sifa K. Nganza ◽  
...  
Keyword(s):  
Preventive Measures ◽  
Health Workers ◽  
Statistical Tests ◽  
Good Practice ◽  
Cross Sectional Study ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Ordered Logistic Regression ◽  
Security Personnel ◽  
Structured Questionnaire

Background: The world is facing the Coronavirus pandemic, which is highly infectious. Several measures have been put in place to prevent its spread among the population. However, for these preventive measures to be effective, the population requires appropriate and sufficient knowledge, attitude, and practices. Thus, a survey to assess knowledge, attitude, and self-reported practice toward measures for prevention of the spread of COVID-19 was conducted among Ugandans.Methods: This was a cross-sectional study conducted among during the lockdown in Uganda. An online structured questionnaire was used, applying a snowballing sampling approach for recruitment of participants 18 years and above and residing in Uganda. Data collection was done from 6th to 15th April 2020, during which 1,763 people participated. We analyzed all data using STATA 14.2, applying appropriate statistical tests.Results: Out of 1,763 participants, 80% were highly knowledgeable. For attitude, 72.4% reported following recommendations given by the Ministry of health to prevent the spread of COVID-19; 89.0% were worried about contracting COVID-19 and 73.3% agreed that COVID-19 can be cured and 99.3% reported good practice toward measures to prevent the spread of COVID-19. According to ordered logistic regression, health workers were 6 times more knowledgeable [aOR:6 (3.51–10.09), p &lt; 0.001] followed by teachers [aOR:5.2 (2.6–10.32), p &lt; 0.001]; students [aOR:3.2 (1.96–5.33), p &lt; 0.001]. On the contrary, the drivers, business entrepreneurs, and security personnel had less knowledge.Conclusion: The results show that the participating Ugandans were knowledgeable and had a positive attitude and good practices. However, there is still a gap in knowledge among drivers, business entrepreneurs, and security personnel. Therefore, there is a need to mobilize the country's population to have the same degree of knowledge, which will have an impact on the attitude and practices toward prevention of the spread of COVID-19.

MORBIDITY PATTERN AMONG ADOLESCENT SCHOOL GIRLS IN RURAL AND URBAN SCHOOL OF JHANSI (U.P.)- A COMPARATIVE CROSS-SECTIONAL SURVEY

2019 ◽  
Vol 3 (9) ◽  
Author(s):  
Shubhanshu Gupta ◽  
Sanjeev Kumar ◽  
Piyush D Swami ◽  
Anjana Niranjan
Keyword(s):  
Health Status ◽  
Adolescent Girls ◽  
Low Socioeconomic Status ◽  
Optimal Level ◽  
Cross Sectional Study ◽  
World Health ◽  
World Population ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Rural And Urban

Background: According to World Health Organization, adolescents constitute about one fifth of the world population, and in India they constitute about 21% of the total population. Most of the surveys show that health status of adolescent girls is at sub-optimal level. Objectives: To assess nutritional status and morbidity pattern among the adolescent girls and to suggest measures for improvement of health status of adolescent girls.  Method: A community based cross-sectional study was carried out among 250 adolescent schoolgirls in Rural and urban field practice area of Jhansi school from January 2017 to July 2014. Results: Among the various morbidities eye problem was seen in maximum no of adolescent girls. Eye problem was present in 44.8% of adolescent girls followed by respiratory 14.7% and ear 13.06% disease. Skin disease was present in 3.2% of adolescent girls, which was more in rural girls 6.7% than in urban girls 1.7%, may be due to better hygienic practice in urban schoolgirls. Conclusions: Rural background, low socioeconomic status, illiteracy, birth rate and order, income and number of members in a family have shown to be significant determinants of morbidity pattern in the adolescent girls. Keywords: Adolescent, anemia, morbidity, vaginal discharge.

CLINICAL SYMPTOMS, BIOCHEMISTRY AND CYTOLOGY OF PLEURAL, PERITONEAL EFFUSIONS

2016 ◽  
pp. 66-71
Author(s):  
Van Mao Nguyen ◽  
Huyen Quynh Trang Pham
Keyword(s):  
Pleural Effusion ◽  
Clinical Symptoms ◽  
Cross Sectional Study ◽  
Malignant Cells ◽  
Sectional Study ◽  
Pleural Effusions ◽  
Cross Sectional ◽  
Breath Sounds ◽  
Peritoneal Effusion ◽  
Neutrophil Leukocytes

Background: The cytology and the support of clinical symptoms, biochemistry for diagnosis of the cases of effusions are very important. Objectives: - To describe some of clinical symptoms and biochemistry of effusions. - To compare the results between cytology and biochemistry by the causes of pleural, peritoneal fluids. Material & Method: A cross-sectional study to describe all of 47 patients with pleural, peritoneal effusions examinated by cytology in the Hospital of Hue University of Medicine and Pharmacy from April 2013 to January 2014. Results: In 47 cases with effusions, pleural effusion accounting for 55.32%, following peritoneal effusions 29.79% and 14.89% with both of them. The most common symptoms in patients with pleural effusions were diminished or absent tactile fremitus, dull percussion, diminished or absent breath sounds (100%), in patients with peritoneal effusions was ascites (95.24%). 100% cases with pleural effusions, 50% cases with peritoneal effusions and 80% cases with pleural and peritoneal effusions were exudates. The percentage of malignant cells in patients with pleural effusions was 26.92%, in peritoneal effusions was 28.57%, in pleural and peritoneal effusions was 42.86%. The percentage of detecting the malignant cells in patients with suspected cancer in the first test was 57.14%, in the second was 9.53% and 33.33% undetectable. Most of cases which had malignant cells and inflammatory were exudates, all of the cases which had a few cells were transudates. Besides, 7.5% cases which had high neutrophil leukocytes were transudates. Conclusion: Cytology should be carry out adding to the clinical examinations and biochemistry tests to have an exact diagnosis, especially for the malignant ones. For the case with suspected cancer, we should repeat cytology test one more time to increase the ability to detect malignant cells. Key words: Effusion, pleural effusion, peritoneal effusion, cytology, biochemistry

Prevalence of COVID-19-like Symptoms among People Living with HIV, and Using Antiretroviral Therapy for Prevention and Treatment

2020 ◽  
Vol 18 (5) ◽  
pp. 373-380 ◽  
Author(s):  
SeyedAhmad SeyedAlinaghi ◽  
Maryam Ghadimi ◽  
Mahboubeh Hajiabdolbaghi ◽  
Mehrnaz Rasoolinejad ◽  
Ladan Abbasian ◽  
...  
Keyword(s):  
Respiratory Symptoms ◽  
Antiretroviral Treatment ◽  
Clinical Symptoms ◽  
Cross Sectional Study ◽  
People Living With Hiv ◽  
Shortness Of Breath ◽  
Sectional Study ◽  
Limited Data ◽  
Cross Sectional ◽  
Living With Hiv

Background: COVID-19 has spread globally with remarkable speed, and currently, there is limited data available exploring any aspect of the intersection between HIV and SARSCoV- 2 co-infection. Objective: To estimate the prevalence of clinical symptoms associated with COVID-19 among people living with HIV (PLWH) in Tehran, Iran. Design: Cross-sectional study. Methods: A total of 200 PLWH were recruited through the positive club via sampling, and completed the symptom-based questionnaire for COVID-19, which was delivered by trained peers. Results: Of 200 participants, respiratory symptoms, including cough, sputum, and shortness of breath, were the most prevalent among participants, but only one person developed symptoms collectively suggested COVID-19 and sought treatments. Conclusions: It appears that existing infection with HIV or receiving antiretroviral treatment (ART) might reduce the susceptibility to the infection with SARS-CoV-2 or decrease the severity of the infection acquired. Further research is needed to understand causal mechanisms.

Depression and Cognitive Impairment in Patients on Hemodialysis: A cross-sectional study

2020 ◽  
Vol 5 (15) ◽  
pp. 185-192
Author(s):  
Nor Jannah Nasution Raduan ◽  
Mohd Razali Salleh ◽  
Ghazali Ahmad ◽  
Zaleha Ismail
Keyword(s):  
Cognitive Impairment ◽  
Publishing House ◽  
Cross Sectional Study ◽  
Hemodialysis Patients ◽  
Education Level ◽  
Sectional Study ◽  
Contributing Factors ◽  
Cross Sectional ◽  
Factors Associated ◽  
Low Education

Depression and cognitive impairment are the most common complications of patients on hemodialysis. The objective of this study is to identify contributing factors to depression and cognitive impairment in hemodialysis patients. This is a cross-sectional study involving 110 hemodialysis patients in Hospital Kuala Lumpur. The samples were recruited through universal sampling. Patients were assessed with the Beck Depression Inventory and Montreal Cognitive Assessment. This study found that 18.2% of patients had depression, and 48.2% had cognitive impairment. Factors associated with depression were unmarried status, low education level, and cognitive impairment. Factors associated with cognitive impairment were low education level, depression, and unemployment. Keywords: hemodialysis, depression, cognitive, ESRD eISSN: 2398-4287© 2020. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BYNC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia. DOI: https://doi.org/10.21834/ebpj.v5i15.2468.

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