scholarly journals Analyzing the Association between Hyperuricemia and Periodontitis: A Cross-Sectional Study Using KoGES HEXA Data

Author(s):  
Soo-Hwan Byun ◽  
Dae-Myoung Yoo ◽  
Jung-Woo Lee ◽  
Hyo-Geun Choi

Hyperuricemia arises from the buildup of excessive uric acid in the blood, and it is implicated in the development of periodontitis. The objective of this study was to investigate the association between hyperuricemia and periodontitis using a cross-sectional study design and Korean Genome and Epidemiology Study Health Examinee (KoGES HEXA) data. This prospective cohort study used epidemiological data from the KoGES from 2004 to 2016. Among 173,209 participants, 8809 with hyperuricemia and 126,465 controls (non-hyperuricemia) were selected. This study defined hyperuricemia as >7.0 mg/dL of uric acid in men and >6.0 mg/dL in women. This study analyzed the history of periodontitis among hyperuricemia and control participants. Participants’ age, gender, income, obesity, smoking, alcohol consumption, and nutritional intake were all examined. Chi-square tests, independent t-tests, and two-tailed analyses were used for statistical analysis. The adjusted OR (aOR) of hyperuricemia for periodontitis was 0.89 (95% confidence interval (CI) = 0.81–0.96, p = 0.005). This study demonstrated that hyperuricemia was associated with periodontitis. This finding meant that elevated uric acid levels could have a positive effect on periodontitis. However, further studies should be performed to determine the range of uric acid levels beneficial to periodontal health.

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Soo Hwan Byun ◽  
Dae Myoung Yoo ◽  
Minwook Chang ◽  
Hyo Geun Choi ◽  
Seok Jin Hong

The objective of this cross-sectional study was to evaluate the association between periodontitis and glaucoma. This prospective cohort study used epidemiological data from the Korean Genome and Epidemiology Study performed between 2004 and 2016. Among 173,209 participants, 9572 patients with periodontitis and 115,332 controls (nonperiodontitis) were selected. We analysed the history of glaucoma in periodontitis and control participants. The participants were interviewed regarding their history of hypertension, diabetes mellitus, hyperlipidaemia, periodontitis, glaucoma, smoking, and alcohol consumption by trained interviewers. A logistic regression model was created to analyse the odds ratio of having a history of glaucoma among patients with periodontitis. Two-tailed analyses using chi-square and independent t-tests were used for statistical analysis. The adjusted odds ratio of periodontitis as a risk factor for glaucoma was 3.44 (95% confidence interval = 2.99–3.97, p < 0.001 ). This study demonstrated that glaucoma was associated with periodontitis.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Seok-Jin Hong ◽  
Byoung-Eun Yang ◽  
Dae-Myoung Yoo ◽  
Sung-Jae Kim ◽  
Hyo-Geun Choi ◽  
...  

Abstract Background Chronic periodontitis is a multifactorial inflammatory disease resulting in patients exhibiting high levels of inflammatory factors causing systemic inflammatory bone destruction that may lead to osteoporosis development. The association between periodontitis and osteoporosis has been documented; however, the findings remain unclear. This study aimed to identify the association between periodontitis and osteoporosis using a cross-sectional study design and Korean Genome and Epidemiology Study (KoGES) health examinee data. Methods This cross-sectional study used epidemiological data from the KoGES during 2004–2016. Of 125,324 participants (age, 40–79 years), 9969 with periodontitis and 115,332 controls (without periodontitis) were selected. We analyzed the history of osteoporosis and fractures of all participants. All participants were examined according to age, sex, income group, obesity, smoking habits, alcohol consumption, and food intake. To analyze the odds ratio (OR) of periodontitis for those with osteoporosis and fractures, a logistic regression model was used. Results The adjusted odds ratio (aOR) of periodontitis for osteoporosis was 2.16 (95% confidence interval [CI], 2.01–2.31; P < 0.001). The aOR of periodontitis for any fracture was 1.54 (95% CI 1.46–1.62; P < 0.001). Conclusion Osteoporosis and fractures are associated with periodontitis. Performing regular oral hygiene and examinations of bone mineral density are recommended to prevent aggravation of osteoporosis and periodontitis.


2013 ◽  
Vol 10 (1-2) ◽  
pp. 51-56 ◽  
Author(s):  
M. S. Rahman ◽  
S. Mithu ◽  
M. T. Islam ◽  
M. J. Uddin ◽  
R. R. Sarker ◽  
...  

Brucellosis is an important bacterial zoonotic disease causing significant economic loss in dairy industries worldwide including Bangladesh. But limited studies are devoted to determine the prevalence of brucellosis in goat in all districts of Bangladesh. Therefore, a cross-sectional study was undertaken to determine the seroprevalence of brucellosis in Black Bengal goats in Nilphamari Sadar and Kishoreganj upazillas of Nilphamari district of Bangladesh using Rose Bengal Test (RBT) as screening test and I-ELISA as confirmatory test. A total of 154 sera samples from Black Bengal goats were collected from Nilphamari district. Epidemiological data on the selected Black Bengal goats were collected using a structured questionnaire. The overall seroprevalence of brucellosis was found to be 2.59% in Black Bengal goats. A significantly (p<0.01) higher prevalence of brucellosis was found in Black Bengal goats with the history of previous abortion (33.33%). An insignificant (p>0.05) but higher prevalence of brucellosis was found in adult Black Bengal goats (>24 months) than young. The prevalence was relatively higher in cross-bred than pure Black Bengal goats, in female than male and in pregnant than non-pregnant Black Bengal goats. The result of the study will provide baseline data for control of brucellosis in goat in Bangladesh.DOI: http://dx.doi.org/10.3329/bjvm.v10i1-2.15646


2020 ◽  
Author(s):  
Larissa Pone Simo ◽  
Valirie Ndip Agbor ◽  
Jean Jacques Noubiap ◽  
Orlin Pagnol Nana ◽  
Pride Swiri-Muya Nkosu ◽  
...  

Abstract Introduction: Sub-Saharan Africa is experiencing a surge in the burden of hypertension, and rural communities seem to be increasingly affected by the epidemic. Objectives: We aimed to determine the prevalence of hypertension, its associated factors, as well as its awareness, treatment, and control rates in rural communities of the Baham Health District (BHD), Cameroon.Design: A community-based cross-sectional study.Setting: Participants from five health areas in the BHD were recruited from August to October 2018.Participants: Consenting participants aged 18 years or older were included. Results: We included 526 participants in this study. The median age of the participants was 53.0 (IQR = 35 – 65) years and 67.1% were female. The prevalence of hypertension was 40.9% (95% confidence interval [CI] = 36.7 – 45.1) were hypertensive with no gender disparity. The overall age-standardised prevalence of hypertension was 23.9% (95% CI = 20.3 – 27.5). Five-year increase in age (adjusted odd’s ratio [AOR] = 1.34; 95% CI = 1.23 – 1.44), family history of hypertension (AOR = 2.22; 95% CI = 1.37 – 3.60), and obesity were associated with higher odds of hypertension (AOR = 2.57; 95% CI = 1.40 – 4.69).The rates of awareness, treatment, and control of hypertension were 37.2% (95% CI = 31.0 – 43.9), 20.9% (95% CI = 16.0 – 26.9), and 22.2% (95% CI = 15.2 – 46.5), respectively.Conclusion: The high hypertension prevalence in this rural community is associated with contrastingly low awareness, treatment, and control rates. Age, family history of hypertension, and obesity are the major drivers of hypertension in this community. Veracious policies are needed to improve awareness, prevention, diagnosis, treatment, and control of hypertension in this rural community.


2021 ◽  
Vol 61 (2) ◽  
pp. 74-81
Author(s):  
Ika Citra Dewi ◽  
Rini Sekartini ◽  
Hartono Gunardi ◽  
Asrawati Nurdin

Background Normal-height children generally have better cognitive function than growth-stunted, short-stature children. Children’s cognitive function reportedly improves with stimulation. However, a correlation between stimulation and cognitive function in children with a history of short stature remains unclear. Objective To assess correlation between stimulation and cognitive function in normal-height vs. short-stature preschool children. Methods A cross-sectional study with consecutive sampling was performed in four sub-district areas in Jakarta. Preschool-aged children and their primary caregivers from previous studies on short stature were eligible for inclusion. An Indonesian version of a questionnaire was used to assess stimulation. A psychologist assessed verbal IQ (VIQ), performance IQ (PIQ), and full-scale IQ (FSIQ) with the Indonesian version of the Wechsler Preschool and Primary Scale of Intelligence (WPPSI). Data were analyzed using Pearson’s correlation and Chi-square tests, and P values <0.05 were considered to be significant. Results Of 62 subjects, 64.5% had normal height and 35.5% had short stature. Both normal-height and short-stature children had similar IQ outcome and history of stimulation. The stimulation was significantly correlated with FSIQ in normal-height children (r= 0.316; P=0.047), but not short-stature children (r=0.049; P=0.828). However, the percentage differences in VIQ, PIQ, and FSIQ between normal-height and short-stature children were not significant (P=0.409, 0.119 and 0.877, respectively). Conclusion  There is a significant correlation between stimulation and IQ in normal-height children. Short-stature preschoolers were not worse in terms of IQ than normal-height preschoolers. Parents and caregivers should be encouraged to provide regular and adequate stimulation to their young children.


Author(s):  
Soo Hwan Byun ◽  
Chanyang Min ◽  
Seok Jin Hong ◽  
Hyo Geun Choi ◽  
Dong Hee Koh

The aim of the present study was to investigate the association between periodontitis and chronic gastritis/peptic ulcer using a cross-sectional study design. The present prospective cohort study used epidemiological data from the Korean Genome and Epidemiology Study (KoGES) recorded from 2004 to 2016. Among 173,209 participants, 9983 with periodontitis and 125,336 with no periodontitis were selected. Histories of chronic gastritis and peptic ulcer between periodontitis and no periodontitis participants were analyzed. The participants were questioned around any history of hypertension, diabetes mellitus, hyperlipidemia, cerebral stroke, ischemic heart disease, periodontitis, body mass index, smoking, alcohol consumption, nutritional intake, and financial income. Chi-square tests, independent t-tests, two-tailed analyses were used in statistical analysis of the data. The adjusted odds ratio of chronic gastritis was 2.22 (95% confidence interval [CI] = 2.10–2.34, p < 0.001) and that of peptic ulcer was 1.86 (95% CI = 1.74–1.98, p < 0.001) in model 2. This study demonstrated that periodontitis was associated with an increased risk of chronic gastritis/peptic ulcer. These findings provide additional evidence for an association between periodontitis and chronic gastritis/peptic ulcer.


Hypertension ◽  
2021 ◽  
Vol 78 (Suppl_1) ◽  
Author(s):  
Mochammad Sja'bani ◽  
Lucky Aziza Bawazier ◽  
Fredie Irijanto ◽  
Zulaela Zulaela ◽  
Agus Widiatmoko ◽  
...  

Background: Serum uric acid levels have been reported to be associated with elevated blood pressure and hypertension events. It is needed to determine the prognostic serum uric acid (SUA) cut-off point to prevent the incidents of prehypertension and hypertension. Methods: This was a cross-sectional study involving a total of 733 participants who a had history of prehypertension in 2007. These participants were selected from “Mlati Study Database” in 2007 by simple random sampling using statistical software. Participants underwent both physical and laboratorical examination. Data were analyzed based on JNC 7 and ACC/AHA 2017 guideline. Results: Based on JNC 7 classification, the analysis using ROC curve showed that the prognostic SUA cut-off point of 4.85 mg/dL was able to indicate the incidents of prehypertension or hypertension in the database (95% confidence interval, CI, 0.532-0.629, p=0.001). Additional analysis using ACC/AHA 2017 guideline as the blood pressure classification was also performed for comparison. Based on ACC/AHA 2017 classification, the ROC curved showed a slightly higher SUA cut-off points than the previous analysis using JNC 7. The prognostic SUA cut-off point of 4.95 mg/dL was able to indicate the events of hypertension stage 1 and stage 2 in the database (95% confidence interval, CI, 0.532-0.615, p=0.001). These results were parallel with the previous study which reported that SUA cut-off points of 5-7 mg/dL (high-normal SUA) and ≥7 mg/dL (high SUA) were associated with the incidents of prehypertension and hypertension. Conclusion: The new SUA cut-off points may be used as an early warning for the development of prehypertension and hypertension in the future.


2011 ◽  
Vol 35 (2) ◽  
pp. 147
Author(s):  
Delmi Sulastri ◽  
Sidhi Sidhi

AbstrakHipertensi pada anak dan remaja sudah merupakan masalah kesehatan mesyarakat yang ada di Indonesia maupun di beberapa negara yang ada di dunia. Hampir 95% kasus hipertensi tidak diketahui penyebabnya atau disebut hipertensi esensial. Beberapa faktor risiko diduga berhubungan dengan peningkatan prevalensi hipertensi ini.Telah dilakukan penelitian dengan desain cross sectional study pada siswa SMU Adabiah yang berusia antara 15 tahun sampai 18 tahun, bertujuan untuk melihat hubungan faktor risiko riwayat keturunan, obesitas, aktifitas fisik dan kebiasaan merokok dengan kejadian hipertensi. Sampel sebanyak 61 orang, kemudian dilakukan wawancara mengenai karakteristik, riwayat keturunan, aktifitas fisik dan kebiasaan merokok serta pemeriksaan tekanan darah dan antropometri. Data yang diperoleh selanjutnya dianalisis menggunakan uji chi-square serta ditampilkan dalam bentuk tabel, gambar dan narasi.Hasil penelitian ini adalah 66.7% siswa mengalami obese, 20.7% mempunyai keturunan hipertensi, 30% dengan aktifitas fisik rendah dan 33.3% mempunyai kebiasaan merokok mengalami hipertensi.Tidak didapat hubungan antara obesitas, riwayat keturunan dan aktifitas fisik dengan kejadian hipertensi dan terdapat hubungan antara merokok dengan kejadian hipertensi (p=0.033).Perlu dilakukan kebijakan yang mengatur tentang peraturan merokok pada anak remaja.Kata kunci : Hipertensi, Riwayat keturunan dan ObesitasAbstractHypertension in children and adolescents is a health problem of the community is in Indonesia as well as in several countries of the world. Almost 95% of the hypertension cases have no cause yet identified or it can be referred to as essential hypertension. Some of the risk factors associated with an increased prevalenceofhypertension. . A research has be made based on cross sectional study study with a cross sectional study Adabiah high school students aged between 15 years to 18 years. The aims to examine the relationship of risk factors history of heredity, obesity, physical activity and smoking habits with the incidence of hypertension. Sample of 61 people were interviewed about the characteristics, history of heredity, physical activity and smoking habits and blood pressure and anthropometry. The dataARTIKEL PENELITIAN148obtained were then analyzed using the chi-square test and displayed in the form of tables, figuresandnarratives.The results of this study were 66.7% of students had obese, 20.7% had a descendants of hypertension, 30% with low physical activity, and 33.3% having ever smoked had hipertensi.Tidak obtained relationship between obesity, a history of heredity and physical activity with the incidence of hypertension and the relationship between smoking with the incidence of hypertension (p = 0033). There needs to be policy regarding smoking regulations in adolescents. Key word : Hypertension, Heredity and Obesity


Author(s):  
Zumrotus Sholichah ◽  
Bondan Fajar Wahyudi ◽  
Corry Laura Junita Sianturi ◽  
Novia Tri Astuti

In 2017 leptospirosis cases occur in new areas in Bantul where cases have never been previously reported. Cases still occur in 2018 with an interval of two months after the first case. Preventive and curative efforts in the context of controlling cases have been carried out by the local health office, in addition to these control efforts, it is also necessary to know the presence of Leptospira in rats and water bodies in the area as well as the history of patients transmission. This study was conducted to provide epidemiological data, especially the status of Leptospira in rats as reservoir animal and water bodies as well as a history of patient activity as basic data for leptospirosis control in Gilangharjo Village.  This cross-sectional study was conducted at the case location in RT 03 Jodog, Gilangharjo Village, Pandak District, Bantul Regency, which was conducted in April 2018. Leptospira infection status was carried out on rats and water bodies by molecular examination, while the history of transmission based on interviews with patients and the result of the examination of Leptospira status. Rat species caught were dominated by R.tanezumi, R. norvegicus and B. indica. Positive rat infected with Leptospira were found in B. indica while in water bodies Leptospira contamination was not found. Infected rat can be a source of transmission for humans and other animals. Most of the patient's activities were carried out in the fields and at home, all of the patients had wounds that were not treated, and had a history of contact with rats that might transmit Leptospira to humans.


BMJ Open ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. e044892
Author(s):  
Wenqing Ni ◽  
Xueli Yuan ◽  
Jia Zhang ◽  
Ping Li ◽  
Hong Min Zhang ◽  
...  

ObjectiveHypertension has become the leading cause of death worldwide. Data on hypertension management among Shenzhen elderly are sparse. Our study aims to investigate treated and controlled hypertension in Shenzhen elderly, and identify relevant predictors.DesignA cross-sectional study.SettingCommunities in Shenzhen, Guangdong, China.ParticipantsA cross-sectional study was conducted. We employed a convenience sampling method to select participants; 124 007 participants aged 65 years and older were recruited from January to December 2018 at local community health centres in Shenzhen.Main outcome measuresData on treatment, control and influencing factors of hypertension were obtained from a standard questionnaire, physical measurements and biochemical analyses.ResultsPrevalence of hypertension was 55.8% among the sample population. Among this group of hypertensive patients, those undergoing hypertension treatment and those with hypertension under control were 54.4% and 32.3%, respectively. Employing multivariate analysis, significant associations were found between treatment and older age, junior high school education and above (OR=1.25, p<0.05), being widowed rather than being married or cohabiting (OR=1.28, p<0.05), engaging in physical activity (OR=1.14, p<0.05), ex-smoker (OR=1.19, p<0.05), habitual drinker (OR=0.72, p<0.05), history of cardiovascular disease (CVD) (OR=2.20, p<0.05) and comorbidities, with a higher probability for those with obesity (OR=1.89, p<0.05), central obesity (OR=1.10, p<0.05), diabetes (OR=1.49, p<0.05) or dyslipidaemia (OR=1.20, p<0.05). Male sex (OR=0.91, p<0.05), junior high school education and above (OR=1.28, p<0.05), engaging in physical activity (OR=1.06, p<0.05), history of CVD (OR=1.82, p<0.05) and individuals who had diabetes (OR=1.52, p<0.05) or dyslipidaemia (OR=1.05, p<0.05) were associated with increased likelihood of control. Aged 80 years and older (OR=0.93, p<0.05), habitual drinker (OR=0.73, p<0.05) and central obesity (OR=0.94, p<0.05) were negatively associated with control of hypertension.ConclusionsWe found a high prevalence of hypertension, but a low prevalence of treatment and control among Shenzhen elderly.


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