Staging Sincerity in Renaissance Italy and Early Modern China; or, Why Real Lovers Quarrel

Poetics Today ◽  
2020 ◽  
Vol 41 (2) ◽  
pp. 281-299
Author(s):  
Casey Schoenberger
Keyword(s):  
Early Modern ◽  
Musical Theater ◽  
Energy Resources ◽  
Modern China ◽  
Physical Sciences ◽  
Strong Connection ◽  
Renaissance Italy ◽  
Relationship Of ◽  
The Relationship ◽  
The Brain

The sixteenth and seventeenth centuries in China and the West saw a wave of skeptical approaches to metaphysics, ethics, and the physical sciences, including a related interest in “playing devil’s advocate” for seemingly weak propositions. This article analyzes two works of musical theater from these geographically remote traditions to argue that use of historically problematic romances to explore the relationship of ethics, emotion, and reason resulted in novel depictions of attachment emotions as neither purely selfless “gut reactions” nor calculating facades. Scenes depicting lovers’ quarrels and morally flawed characters may paradoxically strike audiences as more authentically romantic because they dramatize an aspect of attachment emotions’ functioning recently elucidated by cognitive science, namely, that of “body budgeting” (allocation of energy resources by the brain). Monteverdi and Busenello’s Coronation of Poppaea and Hóng Shēng’s Palace of Lasting Life use contrastive poetic and musical styles to dramatize the debate-like quality inherent in such negotiations, further revealing a strong connection between the affective “ingredients” that make up socially mediated emotion states and the mechanisms by which music and prosody affect them.

Polymeric Nanoparticles for Brain Drug Delivery - A Review

2020 ◽  
Vol 21 (9) ◽  
pp. 649-660
Author(s):  
Subashini Raman ◽  
Syed Mahmood ◽  
Ayah R. Hilles ◽  
Md Noushad Javed ◽  
Motia Azmana ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Surface Modification ◽  
Polymeric Nanoparticles ◽  
Drug Loading ◽  
Preparation Methods ◽  
Brain Drug Delivery ◽  
Polymeric Nanoparticle ◽  
Relationship Of ◽  
The Relationship ◽  
The Brain

Background: Blood-brain barrier (BBB) plays a most hindering role in drug delivery to the brain. Recent research comes out with the nanoparticles approach, is continuously working towards improving the delivery to the brain. Currently, polymeric nanoparticle is extensively involved in many therapies for spatial and temporal targeted areas delivery. Methods: We did a non-systematic review, and the literature was searched in Google, Science Direct and PubMed. An overview is provided for the formulation of polymeric nanoparticles using different methods, effect of surface modification on the nanoparticle properties with types of polymeric nanoparticles and preparation methods. An account of different nanomedicine employed with therapeutic agent to cross the BBB alone with biodistribution of the drugs. Results: We found that various types of polymeric nanoparticle systems are available and they prosper in delivering the therapeutic amount of the drug to the targeted area. The effect of physicochemical properties on nanoformulation includes change in their size, shape, elasticity, surface charge and hydrophobicity. Surface modification of polymers or nanocarriers is also vital in the formulation of nanoparticles to enhance targeting efficiency to the brain. Conclusion: More standardized methods for the preparation of nanoparticles and to assess the relationship of surface modification on drug delivery. While the preparation and its output like drug loading, particle size, and charge, permeation is always conflicted, so it requires more attention for the acceptance of nanoparticles for brain delivery.

scholarly journals The relationship of morphometric changes of the brain with IL-6 levels, systemic inflammation and immune disturbances in the patients with schizophrenia

2021 ◽  
Vol 190 ◽  
pp. 553-559
Author(s):  
Irina K. Malashenkova ◽  
Vadim L. Ushakov ◽  
Sergey A. Krynskiy ◽  
Daniil P. Ogurtsov ◽  
Nikita A. Khailov ◽  
...  
Keyword(s):  
Systemic Inflammation ◽  
Relationship Of ◽  
The Relationship ◽  
The Brain

Chronic stress and brain-derived neurotrophic factor

2021 ◽  
Vol 19 (2) ◽  
pp. 19-27
Author(s):  
A. V. DUBOVAYA ◽  
◽  
S. Ya. IAROSHENKO ◽  
O. A. PRILUTSKAYA ◽  
◽  
...  
Keyword(s):  
Neurotrophic Factor ◽  
Signal Transmission ◽  
Active Agent ◽  
Brain Derived Neurotrophic Factor ◽  
Relationship Of ◽  
The Relationship ◽  
The Brain ◽  
Pituitary Adrenal Axis ◽  
Transmission Information ◽  
Class Representative

The article discusses the influence of stress on the development of nervous tissue, in particular, on the synthesis of neurotrophins (by the example of the brain-derived neurotrophic factor (BDNF), as the most studied class representative). The biological functions of BDNF are discussed as well as its influence on neuroplasticity and the mechanisms by which the protection of neurons is carried out. The article covers the relationship of the stress-implementing system (hypothalamic-pituitary-adrenal axis) and its main active agent (cortisol) with the BDNF synthesis system at its various levels: from the inhibition of mRNA formation to the mechanisms of postsynaptic signal transmission. Information is also provided on changes of BDNF levels due to the maternal deprivation. Epigenetic changes under the influence of glucocorticoids are also reported. However, it is not only glucocorticoids that alter the functioning of the neurotrophin system. The article provides examples of the reverse effect, enabling to consider neurotrophins as a substance with an anti-stress function. In conclusion, the authors give examples of activities that, according to research, can stimulate the synthesis of neurotrophic factor in the brain.

Intake of Anti-Epileptic Drugs and their Influences on Sexual Dysfunctions

2021 ◽  
Vol 3 (2) ◽  
Author(s):  
Roheela Yasmeen ◽  
Nida Mobeen ◽  
Muhammad Amjad Khan ◽  
Irfan Aslam ◽  
Samia Chaudhry
Keyword(s):  
Quality Of Life ◽  
Sexual Dysfunction ◽  
Neurological Disorders ◽  
Penile Erection ◽  
The Central Nervous System ◽  
Relationship Of ◽  
The Relationship ◽  
The Brain ◽  
Psychiatric Problems

Epilepsy which is also called seizures disorder is an uncontrolled action of the central nervous system. Itis not a single disease but a set of neurological disorders. Actually in this situation, the brain does notreceive a precise signal and as a result an abnormal condition is produced that is usually involuntary inaction. In this review, we aimed to focus on the relationship of anti-epileptic drugs with sexual dysfunctionand adaptation of better remedies that improve a patient’s family life. Sexual dysfunction is a commoncomorbidity in people with epilepsy which badly affects their quality of life. Sexual dysfunction is causedby different factors like psychiatric problems, anti-epileptic drugs (AEDs) and social factors etc. Sexualdysfunctions include ejaculatory failure, lessen libido, penile erection in men and irregular menstrual cyclein women. Common drugs such as Topiramate, Gabapentin (GBP), Valproate (VA), Carbamazepine (CBZ),Olanzapine (OL) and Risperidone (RTG) that are in practice to treat epilepsy usually produced adverseeffect on sexual dysfunction. Even though a lot of studies have been carried out to control sexualdysfunction in epilepsy’s patient, but still research is going on. Medicine such as Cyproheptadine,Mianserin, Buspirone, Yohimbine were found better to treat epilepsy with minimum side effects of sexualdysfunction. Moreover, it is also seen that certain vasodilators, folate , and vitamin supplements areeffective in improving the quality of life.

scholarly journals The brain as a fundamental axis in learning process

2019 ◽  
Vol 5 (4) ◽  
pp. 38-45
Author(s):  
Luis Raul Meza Mendoza ◽  
María Elena Moya Martinez ◽  
Angelica Maria Sabando Suarez
Keyword(s):  
Learning Process ◽  
The Body ◽  
Traditional Scheme ◽  
Teaching Learning ◽  
Relationship Of ◽  
The Relationship ◽  
The Brain ◽  
Learning Schemes ◽  
New Strategies ◽  
The Way

Since the beginning of humanity, an attempt has been made to explain the way in which man acquires knowledge, the way in which he assimilates, processes and executes it in order to develop the teaching-learning process that people need throughout of his life, which forces to change the learning schemes using new study methodologies, such as neuroscience, which is a discipline that studies the functioning of the brain, the relationship of neurons to the formation of synapses creating immediate responses which transmits to the body voluntarily and involuntarily, in addition to controlling the central and peripheral nervous system with their respective functions. It is necessary to change the traditional scheme and implement new strategies that allow the teacher to venture into neuroscience, in order to individually understand the different learning processes that students do. As some authors of neuroscience say, the brain performs processes of acquisition, storage and evocation of information, which form new knowledge schemes that generate changes in the attitude of the human being, for this reason teachers are responsible for taking advantage of what It is known about the multiple functions of the brain and be clear about the various ways of acquiring knowledge.

scholarly journals Pola Asuh Orang Tua Terhadap Anak Berdasarkan Golongan Darah

2019 ◽  
Vol 4 (2) ◽  
pp. 114-129
Author(s):  
Hamam Burhanuddin
Keyword(s):  
Social Interaction ◽  
The Body ◽  
Blood Type ◽  
Relationship With God ◽  
3 Dimensional ◽  
Islamic Studies ◽  
Stage Of Development ◽  
Relationship Of ◽  
The Relationship ◽  
The Brain

The study in this paper are explain about the studies of medical (medicine) blood type have the same relationship to human character because the blood producing antibodies and antigens. It could determine a person helpless hold strong or weak body, has an allergy to something or not, in the blood also contains various nutrients (like protein) and also the oxygen being supplied to the brain and nerves and body affect performance someone will then be emanated from the attitude of the person and social interaction. As has been explained, but keep in mind, there is blood in the genes, the nature of which is carried in the body/genotif rightly so it is, but we can not ignore the fenotif/nature arising or visible, this trait appear due to interaction between genes and the environment, so even if the person is smart in the intelligentsia and emotional, but grew up in a bad environment is going to be a bad trait. The theory of personality based on blood type can be used as a reference in parenting children through an understanding of the fundamental principles of the application of personality accompanied by parenting. Furthermore, the taking of steps in the care tailored to the stage of development of the child, in the Qur'an explicitly did not mentioned paragraph that discusses about blood type, but in the Qur'an there are blood (ad-Dam), Islamic studies in the study of Children is seen as a mandate from God, forming 3-dimensional relationships, with parents as the central figure. First, her parents relationship with God that is backed by the presence of children. Second, the relationship of the child (which still need a lot of guidance) with God through his parents. Third, the relationship of the child with both parents under the tutelage and guidance of God.

scholarly journals A comparative study of the brains in pleuronectidae

1937 ◽  
Vol 122 (828) ◽  
pp. 308-343 ◽  
Keyword(s):  
Comparative Study ◽  
Medulla Oblongata ◽  
Royal Society ◽  
Feeding Habits ◽  
Serial Sections ◽  
Naked Eye ◽  
The Family ◽  
Relationship Of ◽  
The Relationship ◽  
The Brain

Part I. The Medulla Oblongata, And Its Variations Acoording To Diet And Feeding Habits In previous communications to this Society the relationship of the habits of feeding and diet to the form and pattern of the medulla oblongata has been described in the cyprinoids, clupeids, and gadoids (Evans, 1931, 1932, 1935). This research takes up a similar study of the brain of the Pleuronectidae. The expense has been borne by a grant from the Royal Society for which the author tenders his grateful thanks. It has seemed to be desirable to extend the observations to the fore- and mid-brain, as in some members of the family these present a very marked development. In order to elucidate some of the problems that arise I have also studied the brain of the eel, and some interesting conclusions have resulted. We find, as a result of examination by the naked eye and of serial sections, that we can divide the following species into four groups as follows: I. The sole, Solea vulgaris .

Ekphrasis

2017 ◽  
Author(s):  
Joel Altman
Keyword(s):  
Early Modern ◽  
Usual Sense ◽  
Early Modern Theatre ◽  
Early Modern English ◽  
Wide Range ◽  
Word Painting ◽  
English Stage ◽  
Relationship Of ◽  
The Relationship ◽  
Flexible Capacity

This chapter examines the use of ekphrasis in early modern theatre, with particular emphasis on its effect on the stage and the relationship of ekphrastic speech to the ongoing action in which it is enunciated. It maps the parameters of ekphrasis on the early modern English stage by considering a few examples of the ways in which ekphrasis instantiates early modern theatricality. It also discusses the expressive potential of ekphrastic speech and its transmission to the listener as well as the ironic uses of ekphrasis as a mode of persuasion, whether directed to oneself, an on-stage auditor, off-stage auditors, or all three. It argues that ekphrasis creates nothing less than what it calls ‘the psyche of the play’ and explains how the unusually flexible capacity of the staged word allows it to be used for a wide range of theatrical techniques, including the usual sense of ‘word-painting’. Finally, it looks at William Shakespeare’s deployment of ekphrasis in his work such asHamlet.

Evolution of vertebrate brain size is associated with sexual traits

2020 ◽  
Vol 70 (4) ◽  
pp. 401-416
Author(s):  
Mao Jun Zhong ◽  
Long Jin ◽  
Jian Ping Yu ◽  
Wen Bo Liao
Keyword(s):  
Sexual Size Dimorphism ◽  
Brain Size ◽  
Finite Energy ◽  
Energy Resources ◽  
Testis Size ◽  
Vertebrate Brain ◽  
Sexual Traits ◽  
The Relationship ◽  
The Brain ◽  
Expensive Tissue Hypothesis

Abstract The expensive tissue hypothesis predicts a trade-off between investments in the brain and other energetically costly organs due to the costs associated with their growth and maintenance within the finite energy resources available. However, few studies address the strength of relationships between brain size and investments in precopulatory (ornaments and armaments) and postcopulatory (testes and ejaculates) sexual traits. Here, in a broad comparative study, we tested the prediction that the relationship between brain size and investment in sexual traits differs among taxa relative to the importance of sperm competition within them. We found that brain size was negatively correlated with sexual size dimorphism (SSD) in anurans and primates, and it tended to decrease with SSD in ungulates and cetaceans. However, brain size did not covary significantly with armaments (e.g., canine length, horn, antler, and muscle mass). Brain size was not correlated with postcopulatory sexual traits (testes and ejaculates). The intensity of covariance between brain size and precopulatory sexual traits decreased with increasing relative testis size.

scholarly journals Complex phosphorylation activity in neurosecretosomal membranes isolated from ox neurohypophyses

1980 ◽  
Vol 188 (3) ◽  
pp. 657-666 ◽  
Author(s):  
M Treiman ◽  
S Worm-Petersen ◽  
N A Thorn
Keyword(s):  
Cyclic Amp ◽  
Gel Electrophoresis ◽  
Major Part ◽  
Sodium Dodecyl ◽  
Experimental Conditions ◽  
Pituitary Glands ◽  
Relationship Of ◽  
The Relationship ◽  
The Brain ◽  
Soluble Components

Homogenates of neural lobes of bovine pituitary glands were fractionated on Ficoll gradients to yield neurosecretosomes (nerve endings). The neurosecretosomes were lysed in a hypo-osmotic buffer and the membranes were separated from the soluble components by centrifugation. On incubation with [gamma-32P]ATP this membrane preparation showed an endogenous phosphorylation activity, which was studied by means of gel electrophoresis in the presence of sodium dodecyl sulphate, and subsequent autoradiography. The major part of the [32P]Pi detected on the gel was shown to be incorporated into three protein bands, termed A, B and C, with minimal mol.wts. of 83 000, 59 000 and 47 000 respectively. The phosphorylation of these three proteins was studied under a variety of experimental conditions. The patterns obtained were partly similar. However, important individual differences were noted, particularly with respect to the effects of cyclic AMP, Mg2+ and Ca2+. On the basis of these differences, it is suggested that in this system the phosphorylation activity is heterogenous, bands A, B and C each reflecting the presence of a different site of phosphate turnover. The relationship of bands A, B and C to several of the previously described phosphoproteins in the brain is discussed.

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