scholarly journals Post-ERCP Pancreatitis: Risk factors and role of NSAIDs in primary prophylaxis

2020 ◽  
Vol 36 (3) ◽  
Author(s):  
Muhammad Haseeb Nawaz ◽  
Shahid Sarwar ◽  
Muhammad Arif Nadeem
Keyword(s):  
Risk Factors ◽  
Pancreatic Duct ◽  
Binary Logistic Regression ◽  
Primary Prophylaxis ◽  
P Value ◽  
Procedure Time ◽  
Chi Square ◽  
Female Ratio ◽  
Creative Commons

Objective: To determine efficacy of diclofenac suppository in reducing post-ERCP pancreatitis (PEP) and identify risk factors for PEP. Methods: This is a placebo-based prospective study at Department of Medicine & Gastroenterology, Services Institute of Medical Sciences / Services Hospital, Lahore performed from January 2018 to June 2019. Patients were randomized to receive diclofenac suppository or glycerine suppository before ERCP. Both groups were compared for PEP using chi square x2 test while risk factors for PEP were determined using binary logistic regression. Results: Total of 165 patients with mean age 49.1(±15.2) and male to female ratio 1/1.6 (63/102) were included. Among 82 (49.7%) patients in diclofenac group, 8 (9.7%) developed pancreatitis while 19(22.9%) of 83(50.3%) in placebo group had PEP (p value 0.02). After multivariate analysis, age>45 years (p value 0.014, OR 3.2), Bilirubin >3 mg/dl (p value 0.004 OR 3.58), time to cannulation> 5 minutes (p value<0.000 OR 9.2), use of precut (p value< 0.000 OR 4.9), pancreatic duct cannulation (p value 0.000 OR 5.46) and total procedure time >30 minutes (p value 0.01 OR 3.92) were risk factors for PEP. Conclusion: Pre-procedure Diclofenac suppository reduces post-ERCP pancreatitis. Age > 45 years, serum bilirubin > 3 mg/dl, cannulation time > 5 minutes, use of precut, pancreatic duct cannulation and procedure time > 30 minutes are risk factors for post-ERCP pancreatitis. doi: https://doi.org/10.12669/pjms.36.3.1804 How to cite this:Nawaz MH, Sarwar S, Nadeem MA. Post-ERCP Pancreatitis: Risk factors and role of NSAIDs in primary prophylaxis. Pak J Med Sci. 2020;36(3):---------. doi: https://doi.org/10.12669/pjms.36.3.1804 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

scholarly journals Detecting chronic kidney disease in diabetic adults by estimating glomerular filtration rate and Serum Creatinine

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Ahmed Kh. Mohammed Almaawi
Keyword(s):  
Risk Factors ◽  
Serum Creatinine ◽  
Cross Sectional Study ◽  
P Value ◽  
Diabetic Patients ◽  
Kappa Index ◽  
Chi Square ◽  
Cross Sectional ◽  
Female Ratio ◽  
Qualitative Variables

Objective: To assess CKD prevalence and risk factors including socio-demography among diabetics by estimating GFR rather than serum creatinine (sCr). Methods: A cross-sectional study was conducted in Dec. 15 2019 through Aug. 15 2020, among 800 diabetics attending tertiary diabetes centers, Baghdad. Data was collected by self-administered questionnaire. SPSS was used for data analysis by (mean, standard deviation and T-test) for quantitative variables and (frequency, percentage, Chi-square test and Kappa index) for qualitative variables. P-Value less than 0.05 was considered significant.  Results: 800 diabetics for last 5-40 years, 95.6% with type2. Aged 52.1±13.2 years, with male: female ratio 1.03:1, 63.6% were with no income, sCr level was 0.86±0.3 mg/dl, and eGFR by Cockcroft Gault (CG) and CKD-EPI equations was 100.4±36.5 & 92.2±25.5 ml/min/1.73m2 respectively. CKD prevalence based on sCr, and eGFR assessed by above equations was 13.3%, 20% and 15.9% respectively (p<0.001). Those with CKD were hypertensive, females, and living in peripheries. Conclusions: Diabetic patients, mainly those with risk factors are more likely to develop CKD. It is better to detect CKD intially by estimating the GFR, rather than serum creatinine level alone. Furthermore, using CKD-EPI equation might be better than the CG formula to estimate the GFR.

scholarly journals Regression Analysis for Analyzing Life Style Risk Factor of Diabetes in Pakistan

2021 ◽  
pp. 94-103
Author(s):  
Zahid Iqbal ◽  
Qaiser
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Cholesterol Level ◽  
Goodness Of Fit ◽  
Significant Risk ◽  
Binary Logistic Regression ◽  
P Value ◽  
Binary Logistic Regression Model ◽  
Goodness Of Fit Test ◽  
Chi Square

Diabetes is a worldwide metabolic disease. In Pakistan prevalence of diabetes is increasing day by day. This research aims to analyze the risk factors associated with the patient in the Malakand division, KPK Pakistan. The data is collected from four districts of Malakand division District Headquarter Hospital for the period year 2018. The insignificant risk factors are eliminated using the backward Elimination method for the Binary logistic Regression model and for a best-fitted model, the AIC technique is used, while the logistic Coefficient is tested with help of Wald statistic and Hosmer-Lemeshow is performed for the Goodness of fit test. The positive and negative association among risk factors with diabetes is checked with the help of a Chi-square and odds ratio. Based on P-value at 5% level of significance the risk factors Age, cholesterol level, Hypertension, Family History, and Obesity are sensitive risk factors to develop diabetes. The AIC also show same best-fitted model while according to Hosmer- Lemeshow 0.844 indicating a better fit and these risk factors are associated with diabetes for the combine data of Malakand division. In each districts, the significant risk factors that affect to develop diabetes are Age, Cholesterol level and Obesity while according to AIC the best-fitted model is that in which the risk factors Gender and Occupation Status are involved the risk factor obesity show low level of precision based on 95% Confidence Interval and Chi-square statistic shows these factors are associated with diabetes.

scholarly journals Seroprevalence and Risk Factors of Syphilis among Blood Donors

2021 ◽  
Vol 17 (2) ◽  
pp. 185-194
Author(s):  
Sachin Singhal ◽  
Dharmesh Chandra Sharma ◽  
Sunita Rai ◽  
Anita Arya ◽  
Prakriti Gupta
Keyword(s):  
Risk Factors ◽  
Blood Donors ◽  
Blood Component ◽  
P Value ◽  
Chi Square ◽  
Female Ratio ◽  
Associated Risk Factors ◽  
And Behavior ◽  
Male To Female ◽  
Advance Knowledge

Abstract Background: Transfusion of blood /component is an essential procedure in modern days of medical practice. As far as safe transfusion is concerned, it is a prime requirement i.e. handles TTIs infections including syphilis and other adverse events. Aims and Objectives: Focus of the present study is to assess seroprevalence and risk factors of Syphilis among blood donors in greater Gwalior  Materials and Methods: The present retrospective descriptive study was conducted over a period of 8 years. All the samples of voluntary and relative blood donors, who came to donate blood, were tested for transfusion transmissible infections. Prevalence of TTIs and syphilis were analyzed in the view of different parameters of donors and along with its associated risk factors. Chi square (X2) test was applied to know the significant (p value) ratio of difference statistically as required. Results: In the present study prevalence of TTIs is 3.44% and for syphilis it is 0.268%, most common age group is 40-51years (41.18%); male to female ratio is insignificant statistically. Ratio of voluntary versus relative donors was 94.21% and 5.79 %  and  male to female was 91.27% and 8.473% were female respectively. Conclusion: An advance knowledge, attitude, and behavior of the volunteer blood donors’ population regarding risk factors will most probably improve public health and increase blood safety and quality.

HUBUNGAN PERAN KADER POSYANDU DENGAN STATUS GIZI BALITA

2018 ◽  
Vol 9 (02) ◽  
pp. 192
Author(s):  
Wiwid Wahyuningsih ◽  
Atik Setiyaningsih
Keyword(s):  
Nutritional Status ◽  
Total Sample ◽  
Nutrition Status ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Central Java ◽  
Good Nutrition ◽  
Nutritional Status Of Children

ABSTRAKLatar Belakang : Keberadaan kader di posyandu sebagai salah satu sistem penyelenggarakan pelayanan sangat dibutuhkan. Mereka adalah ujung tombak  pelayanan kesehatan yang merupakan kepanjangtanganan puskesmas Jawa Tengah tahun 2011 jumlah gizi kurang 5,35% dan gizi buruk 0,10%. Untuk Kabupaten Semarang dari 23.562 balita yang ditimbang pada tahun 2011 gizi lebih 1,13%, gizi baik 93,51%, gizi kurang 4,86% dan gizi buruk 0,49% (DepKes Prov Jateng, 2011). Tujuan Penelitian : Penelitian ini bertujuan untuk mengetahui hubungan peran kader posyandu dengan status gizi balita. Metode Penelitian : Desain penelitian ini adalah survey analitik dengan menggunakan pendekatan cross sectional. Populasi dalam penelitian ini adalah seluruh balita di Posyandu Mawar di Desa Gedangan sejumlah 40 responden, dengan teknik total sampling dan analisa data chi square. Hasil Penelitian : Hasil perhitungan chi square di peroleh X² hitung 10.644 pada df=4, P.value 0.031 dimana probabilitas lebih kecil dari level of significant 5 % (0,001 < 0,05) berarti Ha diterima dan Ho ditolak. Kesimpulan : ada hubungan antara peran kader posyandu dengan status gizi pada balita.Kata Kunci : peran kader , status gizi balitaCADERE ROLE RELATIONSHIP WITH NUTRITIONAL STATUS OF CHILDREN POSYANDUABSTRACTBackground : posyandu cadre in Existence as one of the 56th's service system is urgently needed. They are the tip of the Spear is a kepanjangtanganan health services clinics in Central Java in 2011 the amount of nutrition less 5.35% 0.10% and malnutrition. To Semarang from 23.562 toddler who weighed in 2011 more nutritional 1.13%, 93,51%, good nutrition nutrition less 4.86% and 0.49% poor nutrition (Department of Health Central Java Prov., 2011). Objective : the research aims to find out the relationship role of posyandu cadre with the nutritional status of children. Methods : the design of this research is a survey using the analytic approach of cross sectional. The population in this study are all the toddlers at the Rose in the village of Posyandu Gedangan some 38 respondents, with total sample techniques and data analysis a chi square. The results :. The chi square calculation results in getting X ² count 10.644 on df = 4, P. value 0.031 where probability is smaller than the level of significant 5% (0.001 < 0.05) mean Ha Ho accepted and rejected. Conclusion : there is a connection between the role of cadres of posyandu with nutritional status on toddlers.Keywords : the role of cadres, toddler nutrition status

Role of susceptibility weighted imaging (SWI) in assessment of intra axial brain neoplasms in adults

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Pasant Mohamed Abo-Elhoda Darwish Mohamed Abo-Elhoda ◽  
Hesham Mahmoud Ahmed Mansour ◽  
Yosra Abdelzaher Abdullah ◽  
Eman Ahmed Fouad Darwish
Keyword(s):  
Brain Neoplasms ◽  
Tumor Size ◽  
Venous Blood ◽  
Brain Parenchyma ◽  
P Value ◽  
Susceptibility Weighted Imaging ◽  
Low Grade ◽  
Chi Square ◽  
Cross Sectional

Abstract Background Susceptibility weighted imaging (SWI) is a 3D gradient-echo MR technique that is based on blood oxygen level dependent (BOLD) induced phase effects between the venous blood and the surrounding brain parenchyma. SW-MR imaging allows for noninvasive visualization of small veins at submillimeter resolution and, therefore, is used to depict venous architecture in brain lesions. The extreme sensitivity of SWI for the detection of neovascularity (venous blood), haemorrhage, and calcification has been an indispensable tool for characterization of the internal architecture of brain tumours. Objectives Is to evaluate the role of Susceptibility weighted imaging in assessment of adults Intra axial brain Neoplasms, and its ability to characterize them into high and low grade lesions in comparison to histopathology which will be used as gold standard. Methods A cross sectional study including 31 patients suspecting intracranial brain neoplasm radiologically and clinically, conducted at Private center, the patients were investigated using Siemens machine Magnetom Skyra 3T, the period was between January 2018 till the end of June 2019 . Results Our study included 31 patients. Including 15 female and 16 male patients, with the patient’s age ranging from 20 to 68 years old with median 48 years old ranging from 35.75 (25% percentile) to 58.75 (75% percentile). Among total cases, there were 8 patients with grade 2 glioma, 10 patients with grade 3 glioma and 6 patients with grade 4 glioma, 2 patients with lymphoma and 5 patients with brain metastasis (1 lung cancer and 4 breast cancer). All the patients were evaluated with MRI including SWI sequence with special comment on the number of the intratumoral susceptibility signal (ITSS), the size of the ITSS, its morphology as well as the ratio of the ITSS to the tumor size, which were then correlated with the patient histopathological results obtained later. The study revealed that the best parameter to accurately grade the tumor is the number of ITSS within the lesion with P value 0.001, followed by the size of the ITSS with P value 0.002 and Pearson Chi-Square value equals 20.6, while the lowest one was the ratio of the ITSS to the tumor size with P value 0.002 Pearson Chi-Square value equals 17.3. Our study showed that the morphology alone was not able to accurately grade the tumor with P value 0.007 ( Not significant) Conclusion SWI using 3T MR system provides quite useful information for preoperative tumor grading. There seems to be a strong correlation between pathological grading and that assessed with SWI.

scholarly journals Metabolic Risk Factors and Outcomes in Acute Coronary Syndrome

2020 ◽  
pp. 46-50
Author(s):  
Ritu Attri ◽  
Harsimran Kaur ◽  
Raminderpal Singh Sibia ◽  
Mandip Singh Bhatia
Keyword(s):  
Risk Factors ◽  
Acute Coronary Syndrome ◽  
Positive Family History ◽  
Developed Countries ◽  
P Value ◽  
Health Crisis ◽  
Female Ratio ◽  
Medical College ◽  
Coronary Syndrome ◽  
History Of

Introduction: CAD is the most common cause of mortality in India. It is a common multifarious public health crisis today and a leading cause of morbidity and mortality in both developing and developed countries. Hence, understanding the predominant risk factors among the Indian population is important. Materials and Methods: This was a hospital based age and sex matched case control study, carried out at Government Medical College and Rajindra Hospital Patiala. A total of 100 patients of Acute coronary syndrome were studied. Patients and controls were enquired about  the presence of cardiometabolic risk factors and the significance of association of these risk factors with the occurrence of Acute coronary syndrome was given by p value of  <0.05. Results: Majority of the cases were in the age group 61-70 years (32%) with male to female ratio  of 1.25:1. Significant association was found between ACS and risk factors like smoking, positive family history of IHD, hypertension, diabetes, dyslipidemia, waist hip ratio and body mass index. Overall, most common outcome of ACS in the present study was NSTEMI (45%) followed by STEMI (35%) followed by Unstable angina (20%). Conclusion: Significant association was found between smoking and occurrence of STEMI and significant association was found between Hypertension and occurrence of NSTEMI.

scholarly journals Cardiovascular determinants of renal dysfunction among children and adolescents in South West Nigeria

2020 ◽  
Vol 47 (2) ◽  
pp. 68-73
Author(s):  
A.A. Akinbodewa ◽  
O.A. Adejumo ◽  
A. Ogunleye ◽  
T.T. Oluwafemi ◽  
O.A. Lamidi
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Children And Adolescents ◽  
Cardiovascular Risk Factors ◽  
Renal Dysfunction ◽  
Body Mass ◽  
Cross Sectional Study ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional

Background: New evidences reveal significant association of cardiovascular risk factors to development of chronic kidney disease among children and adolescents but there is paucity of data from Africa. Objectives: We examined the association of cardiovascular risk factors to renal dysfunction among Nigerian pediatric subjects. Materials and method: This was a prospective, cross-sectional study of pediatrics aged 2 to 17 years. Blood pressure, body mass index, serum lipids and creatinine were determined. Their glomerular filtration rate was calculated using the revised Schwartz equation. Data was analyzed with SPSS 20. Test of association was by Chi square at P <0.05. Results: We studied 114 children and adolescents. There were 55 (48.2%) males and 59 (51.8%) females with mean age of 8.99±4.26 years. There were 68 (53.5%) children and 53 adolescents (46.5%). Four (3.5%) subjects had proteinuria ≥1+. Renal dysfunction (eGFR <60ml/ min/1.73m2) was found among 9 (7.9%) participants. Renal dysfunction was higher among children than adolescents (13.1% v 1.9%) (p = 0.027). The presence and clustering of risk factors were higher among subjects with renal dysfunction (p value 0.466, 95% CI 0.19-28.3). Low HDL-c (44.4%), prehypertension(22.2%) and overweight (22.2%) were the most prevalent risk factors among those with renal dysfunction. Only age demonstrated relationship to renal dysfunction in terms of mean difference (p value 0.007, 95% CI, 1.125-6.818). Conclusions: The prevalence and clustering of cardiovascular risk factors is higher among children with renal dysfunction. Age showed association  to renal dysfunction. Dyslipidemia and high body mass have propensity to influence the development of pediatric CKD. Keywords: Cardiovascular risk factors, renal dysfunction, association, pediatrics, Nigeria, Africa.

scholarly journals Penggunaan media sosial dan peran orang tua terhadap kejadian pernikahan dini

2020 ◽  
Vol 14 (3) ◽  
pp. 445-451
Author(s):  
Asnuddin Asnuddin ◽  
Asrini Mattrah
Keyword(s):  
Social Media ◽  
Cross Sectional Study ◽  
Early Marriage ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Chi Square Test ◽  
Role Of Parents ◽  
Use Of Social Media

Social media use: The role of parents' perceptions about social media impact in early marriageBackground: Early marriage is a marriage that is conducted at adolescence, the factors causing early marriage are socio-cultural factors, economic pressure, level of education, difficulty in getting a job, social media, religion and views and beliefsPurpose: To find out the influence of social media and the role of parents on the incidence of early marriageMethod: A quantitative research using descriptive analytical research method with cross sectional study design with variable use of social media with the criteria for the results "active and inactive". For the variable of the role of parents with 2 outcome criteria, namely "influential and not influential". And for the variable incidence of early marriage, there are 2 criteria, namely age 14-16 years and age 17-19 years, the questionnaire used has been through the validity of previous researchers. Then the results of the data obtained were analyzed in the SPSS program using the Chi Square testResults: From the Chi Square test results for social media variables obtained p value = 0.001, then the value of p = 0.001 <0.05 (α) while the role of parents variable Chi Square test results obtained p value = 0.022, therefore the value of p = 0.022 <0.05 (α).Conclusion: Based on the results of the study it can be concluded that, there is a significant influence between the use of social media and the role of parents in the event of early marriage Keywords: Social media; Parents, Early marriagePendahuluan: Pernikahan usia dini adalah perkawinan yang dilakukan pada usia remaja, faktor penyebab pernikahan usia dini adalah faktor sosial budaya, desakan ekonomi, tingkat pendidikan, sulit mendapat pekerjaan, media sosial, agama serta pandangan dan kepercayaan.Tujuan: Untuk mengetahui pengaruh media sosial dan peran orang tua terhadap kejadian pernikahan dini di Kecamatan Marioriawa Kabupaten Soppeng Metode: Penelitian kuantitatif dengan menggunakan metode penelitian deskriptif analitik dengan rancangan cross sectional study dengan variabel penggunaan media sosial dengan kriteria hasil “aktif dan tidak aktif”. Untuk variabel peran orang tua dengan 2 kriteria hasil yaitu “berpengaruh dan tidak berpengaruh”. Dan untuk variabel kejadian pernikahan dini ada 2 kriteria  yaitu umur 14-16 tahun dan umur 17-19 tahun,  kuesioner yang di gunakan sudah melalui uji validitas peneliti sebelumnya. Kemudian hasil data yang di dapatkan dianalisis di program SPSS dengan menggunakan uji Chi SquareHasil: Dari hasil uji Chi Square untuk variabel media sosial didapatkan nilai p=0,001, maka nilai p=0.001<0.05 (α) sedangkan variabel peran orang tua hasil uji Chi Square didapatkan nilai p=0,022, oleh karena itu nilai p=0.022<0.05 (α).Simpulan: Berdasarkan hasil penelitian dapat di simpulkan bahwa, Ada pengaruh yang signifikan antara penggunaan media sosial dan peran orang tua terhadap kejadian pernikahan dini

scholarly journals RISK FACTORS OF WORK STRESS ON FIREFIGHTERS

2021 ◽  
Vol 5 (2) ◽  
pp. 112
Author(s):  
Kristiani Sianturi ◽  
Rini Handayani ◽  
Putri Handayani ◽  
Cut Alia Keumala Muda
Keyword(s):  
Risk Factors ◽  
Interpersonal Relationships ◽  
Work Stress ◽  
Mental Workload ◽  
Interpersonal Relationship ◽  
Bivariate Analysis ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Heavy Work

Background: Firefighters.are often under pressure and get complaints from the public when extinguishing fires. They are often having heavy workloads and time targets to extinguish fires. It makes them have work stress. The initial survey showed of 80% firefighters having moderate-heavy work stress. Purpose: The aim was to know the risk factors of work stress in Firefighters in West Jakarta in 2019. Method: The research design used a cross-sectional design study. The population and samples are 105 Firefighters in West Jakarta (total sampling). The analysis was done in bivariate which was used the chi-square test. Result: The proportion of moderate-heavy work stress in Firefighters is 60.9%. Bivariate analysis show that there are relation of age (p-value < 0.001) interpersonal relationship (p-value = 0.014), and mental workload (p-value = 0.004) with work stress on Firefighters. It also show that there are no relation between level of education (p-value = 0.163), marital status (p-value = 0.071) and years of service (p-value = 0.351) with work stress on firefighter. Conclusion: The risk factors of work stress in firefighters are age, interpersonal relationships, and mental workloads.

scholarly journals Age at Sexual Debut and Multiple Sexual Partnerships among Adolescents in Nigeria: An Assessment of the Mediating Role of the Knowledge of Sexually Transmitted Infections

Adolescents ◽  
2021 ◽  
Vol 1 (4) ◽  
pp. 421-432
Author(s):  
Oluwatobi Abel Alawode ◽  
Hassan Ogunwemimo ◽  
Miracle-Eunice Bolorunduro ◽  
Abayomi Folorunsho Awoleye
Keyword(s):  
Risky Sexual Behavior ◽  
Sexual Debut ◽  
Binary Logistic Regression ◽  
Reproductive Health Services ◽  
Chi Square ◽  
Sexual Partnerships ◽  
Mediating Role ◽  
Awareness Campaigns ◽  
Multiple Sexual Partnerships

Adolescents in Nigeria are at risk of plethora of ills arising from risky sexual behavior in the form of multiple sexual partnerships (MSP). Despite evidence linking MSPs to age at sexual debut, there is a dearth of research among adolescents and the mediating role of the knowledge of STIs has been ignored. Hence, we examined the association between age at sexual debut and MSP and the mediating role of the knowledge of STIs in the relationship among adolescents. We utilized data from the 2018 Nigeria Demographic and Health Survey (n = 3215), employing Chi square test of association and binary logistic regression to address the study objectives. We established strong inverse relationship between age at sexual debut and MSP among adolescents in Nigeria and additionally, found that its interaction with knowledge of HIV and STIs significantly reduced adolescents’ engagement in MSP, i.e., adolescents who first had sex in later years (15+ years) were significantly less likely to have multiple sexual partners compared to adolescents who had early sexual debut (≤14 years). Early, age-appropriate, continuous, and improved awareness campaigns and reproductive health services and interventions for this population subgroup are recommended.

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