scholarly journals Effects of attapulgite dietary supplementation on sow performance in two commercial farms in Greece

2018 ◽  
Vol 68 (2) ◽  
pp. 193 ◽  
Author(s):  
V. KANOULAS ◽  
G. A. PAPADOPOULOS ◽  
G. ARSENOS ◽  
E. D. TZIKA ◽  
P. FORTOMARIS
Keyword(s):  
Litter Size ◽  
Repeated Measures ◽  
Average Daily Gain ◽  
Body Weight Loss ◽  
Control Group ◽  
Treatment Groups ◽  
Performance Indexes ◽  
Commercial Farms ◽  
Underlying Mechanisms ◽  
Reproductive Phases

The present study investigated the effects of attapulgite supplementation in sow diets during gestation and lactation on sow performance. The study comprised two reproductive phases (cycles) in two commercial farrow to finish farms: Farm A (capacity: 550 sows) and Farm B (capacity: 220 sows). The treatment groups were: a) control group (CN): the sows were fed a common gestation or lactation diet; b) attapulgite group (AT): the sows were fed the CN diet supplemented with attapulgite at 0,7% level; c) attapulgite plus group (AT+): the sows were fed the CN diet supplemented with attapulgite (0.7%) and a mix of enzymes, live yeast and amino acids (0.1%), at a total of 0.8% level. Within each cycle the sows included per treatment were: 24 for Farm A; 12 for Farm B. Initially data were analyzed per cycle and per each farm. Data from sows that completed both cycles within each farm, were analyzed by repeated measures analysis. Regarding sow parameters, sow body weight loss during lactation tended to be greater in AT sows compared to CN sows during cycle 1 in Farm B and was greater in AT and AT+ than CN sows in Farm A that completed both cycles (P=0.063 and P=0.023, respectively). A greater litter size 24h postpartum was observed in favour of AT compared to CN group during cycle 1 in Farm A and in sows that completed both cycles in Farm A (P=0.001 and P= 0.011, respectively). Litter size at weaning was greater in sows from the AT group than CN during cycle 1 and 2 in Farm A, in cycle 1 in Farm B and in sows that completed both cycles in Farm A (P=0.004, P=0.037, P=0.037, and P=0.022, respectively). Piglet weight at weaning and average daily gain during lactation were greater in AT group than CN and AT+ in sows that completed both cycles in Farm A (P=0.049 and P=0.040 respectively). Notable similar effects, although not statistically significant, were also observed in Farm B. This field study suggests that attapulgite supplementation in sow diets can improve performance indexes. Further research should investigate the underlying mechanisms involved.

Influence of manure gases on the onset of puberty of replacement gilts

1988 ◽  
Vol 46 (2) ◽  
pp. 277-282 ◽  
Author(s):  
J. R. Malayer ◽  
K. E. Brandt ◽  
M. L. Green ◽  
D. T. Kelly ◽  
A. L. Sutton ◽  
...  
Keyword(s):  
Room Temperature ◽  
Average Daily Gain ◽  
Outdoor Environment ◽  
Control Group ◽  
Food Conversion ◽  
Treatment Groups ◽  
Clean Environment ◽  
Daily Gain ◽  
Group Concentration ◽  
Food Conversion Efficiency

AbstractTo determine whether gases generated during the breakdown of accumulated manure in an environmentally regulated building affects the onset of puberty in gilts, 42 crossbred gilts, born from 1 o t 15 September 1985, were reared indoors from 10 to 30 weeks of age on concrete slats over a pit that was drained and refilled with clean water biweekly (clean group). Forty-two gilts were reared over a pit where manure was allowed to accumulate (control group). These two groups had similar feeding, water, floor space, lighting and room temperature. A third group of 42 crossbred gilts was reared from 10 to 30 weeks of age in an open-front building with a concrete apron (outdoor group). Concentration of aerial ammonia in the control environment was three- to five-fold higher than in either the clean or the outdoor environment (P < 0·001). Average daily gain and food conversion efficiency were similar for the two indoor treatment groups, but the outdoor group gained less weight than either indoor group (P < 0·05). At 26 weeks of age all gilts were exposed to mature boars daily for 2 weeks, then every 2nd day for an additional 2 weeks. A greater proportion of gilts in the clean environment attained puberty 7 days (P < 0·05) and 10 days (P < 0·07) after first exposure to boars. These data suggest that odorous gases, such as ammonia, in the air of environmentally regulated buildings may diminish the stimulatory influence of boars on the onset of puberty in gilts.

scholarly journals Nutritional Supplements Fortified with Oils from Canola, Flaxseed, Safflower and Rice Bran Improve Feedlot Performance and Carcass Characteristics of Australian Prime Lambs

Animals ◽  
2018 ◽  
Vol 8 (12) ◽  
pp. 231 ◽  
Author(s):  
Hung Le ◽  
Quang Nguyen ◽  
Don Nguyen ◽  
Bunmi Malau-Aduli ◽  
Peter Nichols ◽  
...  
Keyword(s):  
Rice Bran ◽  
Average Daily Gain ◽  
Carcass Characteristics ◽  
Control Group ◽  
Feedlot Performance ◽  
Live Animal ◽  
Treatment Groups ◽  
Body Conformation ◽  
Feed Costs ◽  
Dietary Oil

This study investigated live animal performance and carcass characteristics of Australian prime lambs fed oil based polyunsaturated fatty acid (PUFA) enriched pellets in a feedlot system. The tested hypothesis was that supplementation of lambs with a variety of dietary oil based PUFA enriched pellets would enhance growth and carcass characteristics compared with the control lambs fed only with lucerne hay. Seventy-two, 6 months old White Suffolk x Corriedale first-cross prime lambs with an average liveweight (LWT) of 35.7 ± 0.9 kg were allocated to six treatment groups in a completely randomised experimental design. The treatments were: (1) control: lucerne hay only; or lucerne hay plus wheat-based pellets infused with 50 mL/kg dry matter (DM) of oils from (2) rice bran (RBO); (3) canola (CO); (4) rumen protected (RPO); (5) flaxseed (FO) and (6) safflower (SO) dietary sources. All lambs had ad libitum access to lucerne hay and clean fresh water. Supplemented lambs were fed 1 kg of pellet/head/day for 10 weeks. Feed intake, final LWT, average daily gain (ADG), body conformation and carcass characteristics of lambs in the supplemented groups were all greater than for the control group. SO lambs had the lowest ADG of 190.3 g/day. RBO and CO treatments had the lowest feed cost per unit gain of AU$3.0/kg. Supplemented lambs had similar over the hooks (OTH) incomes that were all higher than that of the control group. This empirical evidence-based data demonstrated that supplementation of lambs with RBO and CO had comparatively lower feed costs without compromising ADG, carcass characteristics and OTH income.

150 SERUM TESTOSTERONE CONCENTRATIONS IN BULLS SUPPLEMENTED WITH RUMEN-PROTECTED FAT, ANTIOXIDANTS, OR BOTH

2014 ◽  
Vol 26 (1) ◽  
pp. 188
Author(s):  
M. M. Guardieiro ◽  
F. L. M. Silva ◽  
P. L. J. Monteiro ◽  
A. B. Nascimento ◽  
R. S. Gentil ◽  
...  
Keyword(s):  
Repeated Measures ◽  
Serum Testosterone ◽  
Saline Control ◽  
Control Group ◽  
Standard Diet ◽  
Testosterone Metabolism ◽  
Testosterone Concentration ◽  
Treatment Groups ◽  
Citrus Pulp ◽  
Corn Gluten

Testosterone metabolism occurs primarily in the liver, and circulating concentrations can be influenced by the amount and type of diet provided. Furthermore, there are reports of the influence of circadian rhythms on secretion of testosterone in ruminants. Based on evidence that supplementation with rumen-protected fat may increase circulating concentrations of steroid hormones (Guardieiro et al. 2010 Pesq. Agrop. Bras. 45, 408–414), this study aimed to evaluate the effect of the addition of rumen-protected fat, antioxidants, or both to the diet on serum testosterone concentration in bulls, and to assess whether there is variation in hormone concentrations at different times of the day after feeding. Forty-eight Nelore bulls were confined and assigned to four treatment groups according to the addition of rumen-protected fat, antioxidants, or both to the standard diet (sugarcane bagasse, citrus pulp, corn gluten meal, urea, and mineral salt): F) rumen-protected polyunsaturated fatty acids [PUFA; rich in linoleic, Megalac E®, QGN-Arm & Hammer, Rio de Janeiro, Brazil; 1.5% on dry matter (DM); n = 12]; A) antioxidant (a source of vitamin C and selenium, EconomasE®, Alltech Biotechnology, Buenos Aires, Argentina; 3 g/head/d; n = 12); FA) Megalac E® and EconomasE® (n = 12), or C) nothing (Control group; n = 12). After 75 days of offering diets, jugular blood samples were collected just before IV injections that were performed three times a day (7:00, 13:00, and 19:00 h) with saline (Control group, n = 24) or gonadotropin-releasing hormone (GnRH; 50 μg Gonadorelin, Fertagyl, MSD Saúde Animal, São Paulo, Brazil; GnRH group, n = 48) and 2 h afterward. Bulls were fed 1 h after the first IV GnRH/saline and the diets remained in the bunk for 17 h. Serum testosterone concentrations were measured by radioimmunoassay. Data were analysed by repeated-measures of GLIMMIX of SAS (SAS Institute Inc., Cary, NC, USA). As expected, the GnRH injections increased concentrations of testosterone after 2 h compared to saline (5.4 ± 0.16 v. 3.2 ± 0.16 ng mL–1; P < 0.001). However, after the last injection of GnRH there were lower (P < 0.001) concentrations of testosterone (2.0 ± 0.57) compared to other times. This fact may be explained by the probable association between the greater clearance of testosterone after feeding and the consumption of stock of pituitary LH by GnRH administration. However, there was no effect of diets on circulating testosterone concentration. We may suggest that males can more efficiently control steroid hormone concentrations than females by feedback mechanisms. Financial support was provided by CNPq, FAPESP, Arm & Hammer, Alltech, and EMBRAPA of Brazil.

Effect of feeding fermented extruded corn stover on reproductive performance of pregnant sows

2017 ◽  
Author(s):  
A. Ngalavu ◽  
H. Jiang ◽  
D. Che ◽  
R. Han ◽  
T. L. Tyasi
Keyword(s):  
Corn Stover ◽  
Litter Size ◽  
Reproductive Performance ◽  
Experimental Treatment ◽  
Late Pregnancy ◽  
Control Group ◽  
Treatment Groups ◽  
Serum Hormone ◽  
Fat Thickness ◽  
Performance Results

The objective of the study was to determine the effects of dietary supplementation of fermented extruded corn stover on back fat thickness, reproductive performance and serum hormone in sows during late pregnancy. A total of 48 pregnant sows (24 Landrace and 24 Yorkshire) were randomly assigned into four experimental treatment groups (0%, 10%, 15% and 20% fermented extruded corn stover). Back fat thickness results showed that no significant differences on control group compared to each fermented treatment groups (P>0.05) at 55 and 105 days of gestation, respectively. Reproductive performance results demonstrated that control group had a lower litter size per head than 10% fermented extruded corn stover group (P less than 0.05), respectively. The results showed that leptin hormone was higher in control group than 10%, 15% and 20% treatment groups (P less than 0.05), respectively. Our findings suggested that 10% fermented extruded corn stover increased the litter size per head in pregnant sows.

The Resuscitative and Pharmacokinetic Effects of Humeral Intraosseous Vasopressin in a Swine Model of Ventricular Fibrillation

2017 ◽  
Vol 32 (3) ◽  
pp. 305-310 ◽  
Author(s):  
James M. Burgert ◽  
Arthur D. Johnson ◽  
Jose Garcia-Blanco ◽  
Lawrence V. Fulton ◽  
Michael J. Loughren
Keyword(s):  
Ventricular Fibrillation ◽  
Analysis Of Variance ◽  
Repeated Measures ◽  
Control Group ◽  
Swine Model ◽  
Maximum Plasma ◽  
Publication Type ◽  
Treatment Groups ◽  
Significant Difference ◽  
And Control

AbstractIntroductionThe American Heart Association (AHA; Dallas, Texas USA) and European Resuscitation Council (Niel, Belgium) cardiac arrest (CA) guidelines recommend the intraosseous (IO) route when intravenous (IV) access cannot be obtained. Vasopressin has been used as an alternative to epinephrine to treat ventricular fibrillation (VF).Hypothesis/ProblemLimited data exist on the pharmacokinetics and resuscitative effects of vasopressin administered by the humeral IO (HIO) route for treatment of VF. The purpose of this study was to evaluate the effects of HIO and IV vasopressin, on the occurrence, odds, and time of return of spontaneous circulation (ROSC) and pharmacokinetic measures in a swine model of VF.MethodsTwenty-seven Yorkshire-cross swine (60 to 80 kg) were assigned randomly to three groups: HIO (n=9), IV (n=9), and a control group (n=9). Ventricular fibrillation was induced and untreated for two minutes. Chest compressions began at two minutes post-arrest and vasopressin (40 U) administered at four minutes post-arrest. Serial blood specimens were collected for four minutes, then the swine were resuscitated until ROSC or 29 post-arrest minutes elapsed.ResultsFisher’s Exact test determined ROSC was significantly higher in the HIO 5/7 (71.5%) and IV 8/11 (72.7%) groups compared to the control 0/9 (0.0%; P=.001). Odds ratios of ROSC indicated no significant difference between the treatment groups (P=.68) but significant differences between the HIO and control, and the IV and control groups (P=.03 and .01, respectively). Analysis of Variance (ANOVA) indicated the mean time to ROSC for HIO and IV was 621.20 seconds (SD=204.21 seconds) and 554.50 seconds (SD=213.96 seconds), respectively, with no significant difference between the groups (U=11; P=.22). Multivariate Analysis of Variance (MANOVA) revealed the maximum plasma concentration (Cmax) and time to maximum concentration (Tmax) of vasopressin in the HIO and IV groups was 71753.9 pg/mL (SD=26744.58 pg/mL) and 61853.7 pg/mL (SD=22745.04 pg/mL); 111.42 seconds (SD=51.3 seconds) and 114.55 seconds (SD=55.02 seconds), respectively. Repeated measures ANOVA indicated no significant difference in plasma vasopressin concentrations between the treatment groups over four minutes (P=.48).ConclusionsThe HIO route delivered vasopressin effectively in a swine model of VF. Occurrence, time, and odds of ROSC, as well as pharmacokinetic measurements of HIO vasopressin, were comparable to IV.BurgertJM, JohnsonAD, Garcia-BlancoJ, FultonLV, LoughrenMJ. The resuscitative and pharmacokinetic effects of humeral intraosseous vasopressin in a swine model of ventricular fibrillation. Prehosp Disaster Med. 2017;32(3):305–310.

scholarly journals 47 Effect of Zelnate administered at initial processing in high-risk, newly received beef calves on performance and morbidity

2020 ◽  
Vol 98 (Supplement_2) ◽  
pp. 47-47
Author(s):  
Brady E Martin ◽  
Reagan N Cauble ◽  
Elizabeth Kegley ◽  
Jermey G Powell
Keyword(s):  
High Risk ◽  
Average Daily Gain ◽  
Clinical Score ◽  
Morbidity And Mortality ◽  
Control Group ◽  
Beef Calves ◽  
Treatment Groups ◽  
Treatment Data ◽  
Initial Processing ◽  
Respiratory Treatment

Abstract The objective of this study was to investigate the effects of Zelnate, a DNA immunostimulant, administered to calves (n = 261; BW 253 ± 4.0 kg) upon arrival, on morbidity and mortality, growth performance, and producer costs. Crossbred male beef calves (steers and bulls) were acquired from multiple auction markets and transported to the University of Arkansas stocker unit for a 42-d backgrounding period. Calves were randomly allocated to chute side into treatment groups: 1) Control (CON) in which no immunostimulant was administered or 2) Zelnate (ZEL), DNA immunostimulant administered. Animals were checked daily for signs of morbidity and treated with preplanned antibiotics. Records for morbidity and mortality were kept in addition to body temperature, clinical score, and body weight at the time of treatment. Data were analyzed using the GLIMMIX procedures of SAS. Significance was declared at P &lt; 0.05 and tendencies were observed between 0.05 ≤ P &lt; 0.10. No animals died during the duration of this study; however, Zelnate treated calves tended (P = 0.09) to have a lower relapse rate compared to control calves. Average daily gain was similar (P = 0.60) between the two treatment groups. This study also indicated that the treatment cost (Zelnate plus antibiotics) for the Zelnate group was more expensive than the cost to treat the control group (P &lt; 0.01). Overall, our findings indicate that Zelnate administered upon arrival to high risk calves did not improve morbidity rates and respiratory treatment or affect performance; however, it did increase costs by $9.24 per calf. Based upon these results, Zelnate does not appear to be an effective therapy for BRD when given upon arrival.

scholarly journals Effects of PS-519 combined with thrombolytic therapy in embolic stroke in rat

Stroke ◽  
2001 ◽  
Vol 32 (suppl_1) ◽  
pp. 351-351
Author(s):  
Li Zhang ◽  
Zheng G Zhang ◽  
Michael Chopp ◽  
Peter J Elliott ◽  
Julian Adams
Keyword(s):  
Combination Treatment ◽  
Cell Damage ◽  
Infarct Volume ◽  
Body Weight Loss ◽  
Embolic Stroke ◽  
Therapeutic Window ◽  
Control Group ◽  
Lesion Volume ◽  
Treatment Groups ◽  
Mca Occlusion

P67 We evaluated the effect of a proteasome inhibitor (PS-519) which blocks the activation of NF-kB, alone or combination with thrombolysis, on ischemic cell damage after embolic stroke in rat. Male Wistar rats (n=44) were subjected to embolic middle cerebral artery (MCA) occlusion. Animals were randomly assigned into seven groups: PS-519 treatment groups (n=6 each group) were infused intravenously with PS-519(1.0 mg/kg) at 2 h, 4 h, or 6 h after MCA occlusion, respectively. Combination treatment groups (n=6 each group) PS-519(1.0 mg/kg) followed by rtPA (10 mg/kg) were administered at 2 h, 4 h, or 6 h after MCA occlusion. A control group (n=8) was administered saline at 2 h after MCA occlusion. Rats were sacrificed 7 days after MCA occlusion, infarct volume and gross hemorrhage were measured. In PS-519 treatment groups: infarct volume was significantly (p<0.05) reduced by PS-519 treatment at 2 (19”3.5%) and 4 h (22“3.1%) after MCA occlusion when compared with the control group (34”3.5%). However, no significant reduction of lesion volume was found in the 6 hour treated group (34“2.5%). In the combination treatment groups: infarction volume was significantly (p<0.05) reduced in all three groups compared with control: 2 h (18”4.3%), 4 h (21“3.6%), 6 h (21”4.4%). None of treated rats and 25% of control rats had intracerebral gross hemorrhage. Significant reductions (p<0.05) in neurological deficit and body weight loss were found in all treated groups except the group that treated with PS-519 alone at 6 h. Our results demonstrate that administration of PS-519 alone, or combination with rtPA significantly reduces ischemic cell damage. Moreover, combination treatment with PS-519 and rtPA expands the therapeutic window to at least 6 h after embolic stroke. This suggests that combination therapy might lead to improved neurological outcome beyond that which would occur with neuroprotective treatment or thrombolytics alone.

scholarly journals The effective use of Pietren breed at purebred and crossbred selection

2018 ◽  
pp. 38-45
Author(s):  
O. Khmeliova ◽  
R. Stavetska
Keyword(s):  
Litter Size ◽  
Average Daily Gain ◽  
Live Weight ◽  
Control Group ◽  
Large White ◽  
Litter Weight ◽  
White Breed ◽  
Fat Thickness ◽  
Effective Use ◽  
Experimental Group

The article highlights the problem of finding optimal variants of breeding process in a herd of pigs at purebred and crossbred selection. For this purpose, the control and two experimental groups were formed: ♀ Pietrain × ♂ Pietrain (control), ♀ (Pietrain × Large White) × ♂ Large White (first experimental group), ♀ (Pietrain × Durok) × ♂ Pitren (second experimental group). The analysis of the animals performance in these groups was carried out in 40, 30 and 35 parities, respectively. The research was conducted on the basis of PE «Maglevovany M.I.» in the Donetsk region. It has been established that the higher level of reproductive characteristics have sows of first experimental group, which have heredity of Large White breed, this breed is traditionally considered as a maternal form in cross-breeding schemes. For instance, their litter size at birth is higher than the same indicator in the control and second experimental group (plus 0,5, P<0,05, and 0,3 piglets, respectively); by the litter size at weaning at 28 days (plus 1,6, P<0,001, and 0,6 piglets); by the litter size at 2 months (plus 1,6, P<0,001, and 0,4 piglets). The highest piglet survival at the age of 2 months was in the litters, whose ancestor were boars of Pietrain breed (second experimental group) − plus 3,6 and 2,3 %, respectively, compered to purebred piglets of Pietrain breed and the first experimental group. For such complex indexes as the litter weight at weaning and litter weight at 2 months the first experimental group had an advantage of 18,1 kg (P<0,001) and 31,1 kg (P<0,001) over the control group (purebred Pietrain) and 5,4 kg and 7,6 kg − over the second experimental group. However, the average piglet weight of sows of second experimental group both at 28 days and at 2 months are equal to the average piglet weight of the same age of the first experimental group. The piglets, which are descendants of boars of meat breeds Duroc and Pietrain show a tendency to the faster growth even in an early age. The avarage live weight of pigs of the second experimental group at the age of 100 days and 7 months is higher compared to avarage live weight of pigs of the same age of the control and the first experimental groups – plus 8,5–21,7 kg (P<0,01 for the second experimental group) and 4,4–13,5 kg (P<0,001 for the second experimental group), respectively. At the age of 100 days, the maximum average daily gain was obtained in the second experimental group with an advantage of 190 g (P<0,001) compared to control group and 115 g (P<0,001) compared to the first experimental group. It is obvious that hybrids with the faster growth, which were obtained through crossbreeding ♀ (Pietrain × Duroc) × ♂ Pietrain reach a live weight of 100 kg in a shorter period: they need less time needed to reach 100 kg of live weight – 32 days less (P<0,001 ) compared to purebred animals of Pietrain breed (control group) and 18 days less (P<0,001) compared to hybrids ♀ (Pietrain × Large White) × ♂ Large White (the first control group). By such an indicator as the fat thickness the hybrids of the second experimental group dominate by purebred pigs of the same age of the control group (minus 0,2 mm), that characterize the low ability of meat breed for getting fat. The fat thickness of hybrids of the second experimental group was less by 0,9 mm (P<0,001) compared to the pigs of the first experimental group. Thus, in this herd in order to improve the reproductive qualities of sows, it is suggested to use the crossbreeding scheme ♀ (Pietrain × Large White) × ♂ Large White and to improve the fattening qualities of young animals the optimal is scheme of crossbreeding ♀ (Pietrain × Duroc) × ♂ Pietrain. Key words: pigs, Pietrain, Large White, Duroc, purebred and crossbred selection, reproductive and fattening qualities.

Integrating Low- and High-Level Skills in Instructional Protocols for Writing Disabilities

1995 ◽  
Vol 18 (4) ◽  
pp. 293-309 ◽  
Author(s):  
Virginia W. Berninger ◽  
Robert D. Abbott ◽  
Diane Whitaker ◽  
Leihua Sylvester ◽  
Susan B. Nolen
Keyword(s):  
Hierarchical Linear Modeling ◽  
Repeated Measures ◽  
Growth Curves ◽  
Control Group ◽  
Linear Modeling ◽  
Treatment Groups ◽  
Work Avoidance ◽  
Contact Control ◽  
High Level

Twenty-four children with writing problems were given instruction in handwriting automaticity, spelling strategies, and the composing process (plan, write, review, revise) in 14 one-hour individual tutorials during the summer between third and fourth grade. Half the children (8 boys, 4 girls) received extra practice in composing, while half the children (8 boys, 4 girls) received special training in orthographic and phonological coding. Hierarchical linear modeling of growth curves was used to compare the treatment groups to a non-contact control group (10 boys, 5 girls) on a standard battery at pretest, midtest, posttest, and the two treatment groups with each other on probe measures of handwriting, spelling, and composition in each tutorial session. The treatment groups improved at a faster rate than the control group on some measures of handwriting, spelling, and composition (fluency and quality) in the standard battery, but Verbal IQ did not predict rate of improvement. Differences were found between the two treatment groups in some probe measures of writing and a motivation variable (work avoidance). Repeated-measures ANOVA was used to compare treatment groups to a non-contact control group at pretest, midtest, posttest, and follow-up. Differences between the treatment and control groups favoring the treatment groups were maintained at 6-month follow-up on some handwriting, spelling, and composition (quality) measures. Individual differences were found in learner characteristics prior to treatment and in response to the same treatment. The importance of affect and motivation as well as cognitive variables is emphasized.

scholarly journals Effects of sweetener sucralose on diet preference, growth performance and hematological and biochemical parameters of weaned piglets

2020 ◽  
Vol 33 (5) ◽  
pp. 802-811 ◽  
Author(s):  
Wenwei Zhang ◽  
Holden He ◽  
Limin Gong ◽  
Wenqing Lai ◽  
Bing Dong ◽  
...  
Keyword(s):  
Growth Performance ◽  
Feed Intake ◽  
Average Daily Gain ◽  
Control Group ◽  
High Dose ◽  
Free Access ◽  
Health State ◽  
Weaned Piglets ◽  
Treatment Groups ◽  
Diet Preference

Objective: Two experiments were conducted to investigate the effects of dietary sucralose on diet preference and growth performance of weaned piglets, and a third experiment was a 28-d safety study to examine if high-dose sucralose could affect the health state of weaned piglets.Methods: In experiment one, 48 piglets had free access to a corn-soybean based diet and the same diet supplemented with 150 mg/kg sucralose for 15 d. In experiment two, 180 piglets were blocked into 5 treatments with 6 replications. They were fed basal diets supplemented with 0, 75, 150, 225, and 300 mg/kg sucralose for 28 days. In experiment three, 108 piglets were randomly assigned to 3 treatments and fed diets supplemented with 0, 150 (suitable level), and 1,500 (ten-fold suitable level) mg/kg sucralose for 28 d.Results: The experiment 1 showed that piglets preferred (p<0.05) diets containing sucralose during experimental period. In experiment 2, piglets fed a diet supplemented with 150 mg/kg sucralose had a higher average daily gain (ADG) and average daily feed intake (ADFI) than pigs in the control group and other treatment groups during the experiment period. The concentrations of sucralose over 150 mg/kg may decrease feed intake. However, no difference in feed conversion ratio was observed. In experiment 3, piglets fed diet supplemented with 150 mg/kg sucralose had a higher ADG and ADFI than that of pigs in the control group and 1,500 mg/kg treatment groups during the experiment period. Clinical blood metabolites, organ index and histological morphology were not significantly different between sucralose treatments.Conclusion: Sucralose can promote feed intake and thereby improve growth performance of weaned piglets. Moreover, inclusion of 1,500 mg/kg sucralose was demonstrated to have no observed adverse effects. Supplementing 150 mg/kg sucralose for weaned piglets is recommended in this study.

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