scholarly journals The relationship between umbilical–portal–systemic venous shunt and outcome in 11 fetuses

F1000Research ◽  
2021 ◽  
Vol 10 ◽  
pp. 1058
Author(s):  
Liu Fang ◽  
Wang Xueyan ◽  
Xiao Yangxue ◽  
Zhang Xiaohang ◽  
Ran Suzhen ◽  
...  
Keyword(s):  
Growth And Development ◽  
Chromosomal Abnormalities ◽  
Fetal Outcome ◽  
Ductus Venosus ◽  
Ratio Increase ◽  
Genetic Characteristics ◽  
Cardiothoracic Ratio ◽  
Venous Shunt ◽  
Portal Systemic Shunt ◽  
The Relationship

Objective: To investigate the relationship between congenital umbilical–portal–systemic venous shunt (UPSVs) and fetal outcome. Methods: The ultrasonographic and genetic characteristics of 11 cases of UPSVS were retrospectively analyzed and followed up to postnatal. Results: Four cases of ductus venosus -- systemic shunt (DVSS), one case of extrahepatic portal -- systemic shunt (EHPSS), and one case of umbilical systemic shunt (USS) combined with intrahepatic portal-systemic shunt (IHPSS), six cases of intrahepatic portal-systemic shunt (IHPSS) were observed. chromosomal abnormalities were observed in 9.1% (1/11), other ultrasonic abnormalities in 54.5% (6/11), cardiothoracic ratio increase in 45.5% (5/11), fetal growth restriction in 36.4% (4/11), edema was in 9.1% (1/11) and live birth was in 72.7% (8/11). Conclusion: The incidence of IHPSS is the highest and the outcome is the best. Shunt of DVSS and IHPSS can be closed spontaneously after birth. When the prenatal diagnosis is congenital UPSVs, chromosomal abnormalities and other ultrasonic abnormalities should be required further examination, and the growth and development of the fetus should be closely monitored.

Ductus venosus agenesis and fetal malformations: what can we expect? – a systematic review of the literature

2018 ◽  
Vol 47 (1) ◽  
pp. 1-11 ◽  
Author(s):  
Diana Pacheco ◽  
Otília Brandão ◽  
Nuno Montenegro ◽  
Alexandra Matias
Keyword(s):  
Systematic Review ◽  
Chromosomal Abnormalities ◽  
Rare Condition ◽  
Venous Drainage ◽  
Ductus Venosus ◽  
Review Of The Literature ◽  
Management Options ◽  
Venous Shunt ◽  
Fetal Malformations ◽  
Extracardiac Abnormalities

Abstract Background The ductus venosus agenesis (DVA) is a rare condition with a variable prognosis that relies partly on the presence of associated conditions. The purpose of our study was to analyze the literature regarding the post-natal outcome of fetuses with DVA associated with fetal malformations, in order to discuss the best management options for couples. Methods We performed a systematic review of the literature of MEDLINE and SCOPUS electronic databases in a 25-year period from 1992 to September 2017. Methods We found 340 cases of DVA associated with fetal abnormalities. The most common chromosomal abnormalities were: monosomy X (12/48, 25%), trisomy 21 (11/48, 22.9%) and trisomy 18 (6/48, 12.5%). From the 340 cases with DVA, in 31 cases the umbilical venous shunt type was not reported. Of the fetuses, 60.8% (188/309) had an extrahepatic umbilical venous drainage while 39.2% (121/309) presented an intrahepatic connection. The DVA was associated in 71 cases (23.0%) with cardiac abnormalities, in 82 cases (26.5%) with extracardiac abnormalities and in 85 cases (27.5%) with both cardiac and extracardiac abnormalities. Conclusion DVA associated with both cardiac and extracardiac malformations may confer a poorer fetal outcome, a clinically relevant fact that should clarify what can be expected from this entity and help prenatal counseling.

Thickness of endometrium: predictor of the effectiveness of IVF/ICSI programs (literature review)

GYNECOLOGY ◽  
2018 ◽  
Vol 20 (1) ◽  
pp. 113-116
Author(s):  
L A Bagdasaryan ◽  
I E Korneyeva
Keyword(s):  
Assisted Reproductive Technologies ◽  
Endometrial Thickness ◽  
Molecular Genetic ◽  
Uterine Cavity ◽  
Reproductive Technologies ◽  
Genetic Characteristics ◽  
Vitro Fertilization ◽  
Need To Evaluate ◽  
The Relationship

The aim of the study is to systematically analyze the data available in the modern literature on the relationship between endometrial thickness and the frequency of pregnancy in the program of assisted reproductive technologies (ART). Materials and methods. The review includes data from foreign and domestic articles found in PubMed on this topic. Results. The article presents data on the relationship between the thickness of the endometrium and the frequency of pregnancy in ART programs. The greatest number of studies is devoted to the evaluation of the relationship between the thickness of the endometrium and the frequency of pregnancy on the day of the ovulation trigger. Data are presented on the existence of a correlation between the thickness of the endometrium measured on the day of the ovulation trigger and the frequency of clinical pregnancy, as well as data on the need to evaluate the structure of the endometrium and the state of subendometric blood flow. The importance of multilayered (three-layered) endometrium as a prognostic marker of success in in vitro fertilization/intracytoplasmic sperm injection programs in the ovum is emphasized. The conclusion. The thickness of the endometrium can not be used as an argument for canceling the cycle or abolishing embryo transfer to the uterine cavity. Further studies in this direction are needed with a study of the morphological and molecular genetic characteristics of the endometrium, which in the future will allow us to evaluate the relationship between the thickness of the endometrium and the probability of pregnancy.

scholarly journals Study on clinical and genetic characteristics of male patients with non-obstructive azoospermia

2021 ◽  
Vol 141 (5) ◽  
pp. 39-45
Author(s):  
Nguyen Hoai Bac ◽  
Hoang Long
Keyword(s):  
Sex Chromosome ◽  
Chromosomal Abnormalities ◽  
Klinefelter Syndrome ◽  
Obstructive Azoospermia ◽  
Genetic Characteristics ◽  
Azfc Deletion ◽  
Genetic Abnormalities ◽  
History Of ◽  
Male Patients ◽  
Infertile Patients

We examined 501 patients with non - obstructive azoospermia to evaluate clinical, subclinical, and genetic characteristics. The results show that the average age of patients in the study was 29.8 ± 5.5 years. Primary infertility accounts for the majority, with a rate of 90.3%. There was 38.6% of patients had a history of mumps orchitis. The average levels of FSH, LH, testosterone were 31.6 ± 16.5 mIU/mL, 15.5 ± 10 mIU/mL and 12.8 ± 7.13 nmol/L, respectively. The prevalence of chromosomal abnormalities was 30.7%. Of these, the sex chromosome aneuploidy with 47,XXY karyotype (Klinefelter syndrome) accounted for 27.3%. The incidence of AZF microdeletion was 13.8%. Of these, AZFc deletion was the most common at the rate of 42.1%, AZFa deletion, which accounted for 2.6%, were the least prevalent, and the frequency of AZFd deletion was 5.3%. However, there was no solitary AZFb deletion, which combined with other AZF deletions with 34.2%. Our research shows that mumps orchitis and chromosomal abnormalities are the leading causes of azoospermia. Screening for genetic abnormalities plays an important role in infertile patients with non - obstructive azoospermia.

scholarly journals Pendidikan Ibu dan Durasi Pemberian Air Susu Ibu dalam Peningkatan Kecerdasan Siswa Usia Sekolah Dasar

2013 ◽  
pp. 169
Author(s):  
Maryam Said ◽  
Hadi Pratomo
Keyword(s):  
Random Sampling ◽  
Growth And Development ◽  
Education Level ◽  
Department Of Education ◽  
Cross Sectional ◽  
Systematic Random Sampling ◽  
Cross Sectional Design ◽  
High Level ◽  
Duration Of Breastfeeding ◽  
The Relationship

Riwayat pemberian Air Susu Ibu (ASI), karakteristik ibu dan anak serta pola asuh berpengaruh terhadap kecerdasan anak. Penelitian ini bertujuan untuk mengetahui proporsi tingkat kecerdasan anak, riwayat pemberian ASI, karakteristik ibu dan anak, serta faktor dominan yang berhubungan dengan tingkat kecerdasan anak pada siswa SDSN Pekayon Jaya VI Kota Bekasi. Penelitian kuantitatif dengan desain potong lintang dengan metode systematic random sampling dengan jumlah sampel sebesar 166 responden (siswa/i yang berumur 7 - 9 tahun) beserta ibunya. Penelitian ini dilaksanakan pada bulan Mei 2013. Pada siswa dilakukan tes kecerdasan menggunakan tes Raven sedangkan ibunya mengisi kuesioner. Hasil penelitian menunjukkan tingkat kecerdasan rendah 6%, rata-rata 36,7%, dan tinggi 57,2%. Variabel yang berhubungan dengan kecerdasan adalah durasi pemberian ASI dan pendidikan ibu. Pendidikan ibu adalah faktor dominan terhadap kecerdasan, bahwa ibu yang berpendidikan tinggi berpeluang mempunyai anak dengan kecerdasan tinggi yaitu 3,556 kali lebih besar dibandingkan ibu berpendidikan rendah setelah dikontrol variabel durasi ASI. Untuk Dinas Pendidikan Kota Bekasi agar menyelenggarakan berbagai aktivitas seperti seminar/pelatihan/konseling bagi orang tua murid tentang pentingnya peran orangtua terhadap tumbuh kembang anak.Breastfeeding history, mother and children characteristics, and child care are considered influential on child intellegence. This study aimed to determine the proportion of exclusive breastfeeding, the level of childrens intellegence, mother and children characteristics, the relationship between duration of breastfeeding with the level of students intellegence. This research used a cross-sectional design and through systematic random sampling with a sample size of 166 respondents (students aged 7 - 9 years old) and their mothers. The intellegence was tested using the Raven test while their mothers were interviewed. The results showed that the level of childrens intellegence was high (57.2%), average (36.7%), and low (6%). Those variables which related to the intellegence level were duration of breastfeeding and the level of mothers education. The mothers education level is one of the factors which has higher effect, againts the childrens intellegence. Those mothers who have high level education will have probability 3,556 to have their children with high level intellegence (after controlling the duration breastfeeding). Suggestion; The Department of Education Bekasi city to organize activities relevant to the improving of parents in growth and development of their children through seminars/training/counseling.      

scholarly journals Environmental and psychological research on sandpits as children's play equipment, children's play, and the importance of sandpits in children's development and cultural creation

Impact ◽  
2021 ◽  
Vol 2021 (4) ◽  
pp. 16-18
Author(s):  
Hiroyuki Kasama
Keyword(s):  
19Th Century ◽  
Growth And Development ◽  
Psychological Research ◽  
High Tech ◽  
Women's College ◽  
Children's Play ◽  
Developmental Growth ◽  
Children’S Play ◽  
The Impact ◽  
The Relationship

Sandpits are commonly found in playgrounds but in a world full of high-tech entertainment is their role in the developmental growth of young children undervalued? Professor Hiroyuki Kasama, Doshisha Women's College, Japan, is exploring the impact of sandpits on children, including the role they can play in deepening the relationship between parent and child. Sandpits first came about in Europe in the mid-19th century but have recently become unfavourable to many parents who consider them to be 'dirty' play. However, playing with sand yields important benefits, including the use of natural materials and the fact it provides a valuable sensory experience that enables children to build on emotional, social and athletic skills. Kasama is investigating the important potential of sandpits as well as working on childcare and education programmes that use sandpits for learning. Kasama is keen to improve the sandpit environment by standardising the type of sand used in order to make play more effective and observing the suitability of the sand by observing children's play and the reactions of their caregivers. Kasama and the team have also supervised the installation of indoor sandpits that can be used year-round. Ultimately, by clarifying the significance and necessity of playing with sand and discovering its potential, Kasama is aiming to provide children with effective environments that promote growth and development.

scholarly journals Chromosome 10 Abnormality Predicts Prognosis of Neuroblastoma Patients With Bone Marrow Metastasischromosome 10 Abnormality Predicts Prognosis of Neuroblastoma Patients With Bone Marrow Metastasis

2021 ◽  
Author(s):  
Chiyi Jiang ◽  
Xiao Xu ◽  
Binglin Jian ◽  
Xue Zhang ◽  
Zhixia Yue ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Clinical Characteristics ◽  
Chromosomal Abnormalities ◽  
Abnormal Chromosome ◽  
Mycn Amplification ◽  
Chromosome 10 ◽  
Orbital Metastases ◽  
One Year ◽  
The Relationship

Abstract Background Neuroblastoma (NB) is the most common extracranial solid tumor in children with high heterogeneity and concealed onset. The mechanism for its occurrence and development has not been revealed. The purpose of this study was to summarize the clinical characteristics of children with NB and abnormal chromosome 10. To investigate the relationship between the number and structure of chromosome 10 abnormality and NB prognosis.MethodsWe used chromosome G-banding in the first diagnosis to evaluate the genetics of chromosomes in patients with NB, and follow up their clinical characteristics and prognosis. All participants were diagnosed with NB in Hematology Oncology Center, Beijing Children’s Hospital from May 2015 to December 2018, and were followed up for at least one year. ResultsOf all 150 patients with bone marrow metastases, 42 were clearly diagnosed with chromosomal abnormalities. There were 13 patients with chromosome 10 abnormalities definitely, and the loss of chromosome 10 was the most common decrease in the number of chromosomes. These 13 patient had higher LDH, lower OS and EFS than that of children in abnormal group without chromosome 10 abnormality. Eight patients both had MYCN amplification and 1p36 deletion. Two of them had optic nerve damage and no vision, and 1 had left supraorbital metastases five months after treatment. Among the 16 children with suspected chromosome 10 abnormalities, 3 also had orbital metastases. ConclusionsThe above results showed that chromosome 10 might be a new prognostic marker. MYCN amplification and 1p36 deletion may be related with chromosome 10 abnormalities in NB. And NB patients with abnormal chromosome 10 were prone to have orbital metastases.

scholarly journals Melatonin in plants: what we know and what we don’t

2021 ◽  
Vol 5 ◽  
Author(s):  
Zixin Zhang ◽  
Yang Zhang
Keyword(s):  
Abiotic Stresses ◽  
Growth And Development ◽  
Current Knowledge ◽  
Future Research ◽  
Signal Transduction Pathways ◽  
Biotic And Abiotic Stresses ◽  
Research Directions ◽  
Genetic Characteristics ◽  
Future Research Directions ◽  
Biosynthesis Regulation

Abstract Melatonin is an endogenous micromolecular compound of indoleamine with multiple physiological functions in various organisms. In plants, melatonin is involved in growth and development, as well as in responses to biotic and abiotic stresses. Furthermore, melatonin functions in phytohormone-mediated signal transduction pathways. There are multiple melatonin biosynthesis pathways, and the melatonin content in plants is greatly affected by intrinsic genetic characteristics and external environmental factors. Although melatonin biosynthesis has been extensively studied in model plants, it remains uncharacterized in most plants. This article focuses on current knowledge on the biosynthesis, regulation and application of melatonin, particularly for fruit quality and preservation. In addition, it highlights the links between melatonin and other hormones, as well as future research directions.

Pengetahuan Dengan Kemampuan Komunikasi Terapeutik Perawat Pada Pasien Anak Usia Prasekolah (Knowledge and Nurses' Therapeutic Communication Skills in Pre-School Age Patient)

2020 ◽  
Vol 9 (2) ◽  
pp. 102
Author(s):  
Idayati Idayati ◽  
Diny Vellyana ◽  
Sondang Sondang
Keyword(s):  
Communication Skills ◽  
Growth And Development ◽  
Pediatric Patients ◽  
Preschool Age ◽  
P Value ◽  
Therapeutic Communication ◽  
Cross Sectional ◽  
Spearman Rank ◽  
Relationship Of ◽  
The Relationship

AbstractHaving treatment in a hospital (hospitalization) is an unpleasant and threatening experience for everyone, especially for children who are still in the process of growth and development. One way to resolve this problem is to use therapeutic communication effectively which will and will be carried out nursing actions. To communicate with children, special approaches or techniques are needed so that the relationship can run well according to the child's growth and development. One of the predisposing factors according to Lawrencen Green's theory is knowledge, when a nurse has good knowledge, her ability in therapeutic communication will be good too. The aim of study is to determine the relationship of knowledge with the therapeutic communication skills of nurses in pediatric patients. This research uses survey analytic methode with crosssectional. Sample in the study were 66 nurses in inpatient rooms of Graha Husada Hospital,technique purposive samplingfor sampling.Data analysis using the Spearman Rank (Rho) correlation test with a significance level (α = 0.05)  is obtained p value 0.025 (p <0.05). There is relationship of knowledge with therapeutic communication ability of nurses in pediatric patients treated at Graha Husada Hospital  Bandar Lampung. Nurses are expected to be able to improve services in providing nursing care to pediatric patients, especially preschool age pediatric patients. AbstrakBerobat di rumah sakit (hospitalisasi) merupakan pengalaman yang tidakmenyenangkan dan mengancam bagi setiaporang,terutama bagi anak – anak yang masih dalam proses tumbuh kembang. Salah satu cara untuk mengatasi masalah tersebut adalah dengan menggunakan komunikasi terapeutik secara efektif yang akan dilakukan tindakan keperawatan. Untuk berkomunikasi dengan anak diperlukan pendekatan atau teknik khusus agar hubungan dapat berjalan dengan baik sesuai dengan tumbuh kembang anak. Salah satu faktor predisposisi menurut teori Lawrence Green adalah pengetahuan, bila perawat memiliki pengetahuan yang baik maka kemampuannya dalam komunikasi terapeutik juga akan baik. Tujuan penelitian ini untuk mengetahui hubungan pengetahuan dengan keterampilan komunikasi terapeutik perawat pada pasien anak. Penelitian ini menggunakan metode survey analitik dengan pendekatan cross sectional. Sampel dalam penelitian ini adalah 66 perawat ruang rawat inap Rumah Sakit Graha Husada dengan teknik pengambilan sampel purposive sampling. Analisis data menggunakan uji korelasi Spearman Rank (Rho) dengan tingkat signifikansi (α = 0.05) diperoleh dari niai p 0.025 (p<0.05). Ada hubungan pengetahuan dengan kemampuan komunikasi terapeutik perawat pada pasien anak yang di rawat di RS Graha Husada Bandar almpung. Perawat diharapkan mampu meningkatkan pelayanan dalam memberikan asuhan keperawatan kepada pasien anak khususnya pasien anak usia prasekolah.

THE RELATIONSHIP OF PLACENTAL THICKNESS WITHGESTATIONALAGE IN THIRD TRIMESTER AND PROBABLE FETAL OUTCOME

2021 ◽  
pp. 64-66
Author(s):  
Sambhunath Bandyopadhyay ◽  
Ritayan Sasmal ◽  
Debarshi Jana
Keyword(s):  
Birth Weight ◽  
Gestational Age ◽  
Age Determination ◽  
Fetal Outcome ◽  
Inclusion Criteria ◽  
Third Trimester ◽  
Relationship Of ◽  
The Relationship ◽  
Placental Thickness

Accurate gestational age determination is very important for management of continuation and termination planning of the pregnancy. rd To establish placental thickness as a parameter for determination of gestational age and fetal growth pattern at 3 trimester. 100 primigravida women who are fullling the inclusion criteria and attend gynae &obs OPD or admitted in their third trimester at IPGME&R from January 2017 to june 2018. Placental thickness at 3rd trimester USG scan is moderately correlated with gestational age, if placental thickness expressed in millimeter then it correlated with gestational age at weeks. rd st Placental thickness with >3.2 cm (32 mm) at 3 trimester almost associated with good fetal outcome, with APGAR score >8 at 1 min and birth weight >2500 gm.

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