scholarly journals functional hemispheric asymmetry in boys and girls with arterial hypertension

2016 ◽  
Vol 1 (5) ◽  
pp. 46-48
Author(s):  
Ревякина ◽  
Yuliya Revyakina ◽  
Прохорова ◽  
Zhanna Prokhorova ◽  
Косовцева ◽  
...  
Keyword(s):  
Arterial Hypertension ◽  
Cardiovascular System ◽  
Hemispheric Asymmetry ◽  
Comparison Group ◽  
Statistical Significance ◽  
Main Group ◽  
Healthy Children ◽  
Normal Functioning ◽  
The Asymmetry ◽  
The One

Peculiarities of hemispheric asymmetry in 59 boys and 39 girls with arterial hypertension (mean age – 15.1 ± 1.5) were studied. The comparison group of healthy children included 60 boys and 37 girls (mean age – 14.9 ± 1.3).The total indicators of sensorimotor asymmetry showed significant deviations in formation of functional hemispheric asymmetry only in the group of boys. At the same time, differences of the asymmetry indicators between main group of girls and the one of comparison were quite moderate and did not reach the level of statistical significance. It is associ-ated with adaptation features of the boys with hypertension to changes of normal functioning of cardiovascular system.

scholarly journals BIOMARKERS OF OSTEO-DEFFICIENCY IN THE COURSE OF SECONDARY OSTEOPOROSIS IN PATIENTS WITH COMORBID CHRONIC PANCREATITIS AND ARTERIAL HYPERTENSION

2020 ◽  
Vol 20 (4) ◽  
pp. 16-20
Author(s):  
T.I. Viun ◽  
L.M. Pasieshvili ◽  
S.V. Viun ◽  
A.S. Marchenko ◽  
O.V. Karaya
Keyword(s):  
Chronic Pancreatitis ◽  
Acid Phosphatase ◽  
Arterial Hypertension ◽  
Comparison Group ◽  
Practical Importance ◽  
Main Group ◽  
Secondary Osteoporosis ◽  
Control Group ◽  
Tartrate Resistant Acid Phosphatase ◽  
Detection Of Biomarkers

The prevalence of comorbidities has been growing for the last decades. Therefore, the detection of biomarkers for diagnostic and prognostic purposes is of great practical importance. The aim of this study was to assess the biomarkers of osteo-defficiency in the course of secondary osteoporosis in patients with comorbid chronic pancreatitis and arterial hypertension. We examined 110 patients with chronic pancreatitis: 70 of them had comorbid hypertension, and 40 patients were found as having no comorbidities. The age of patients ranged from 33.2 ± 2.1 (main group) and 32.9 ± 3.1 years (comparison group); women predominated (72.9% and 70%, respectively). The control group includes 78 healthy individuals of the same age and sex. Diagnostic investigation included studying clinical and anamnestic characteristics of patients (duration of the disease, manifestations of the course, frequency of recrudescence, fractures) and biochemical parameters of bone metabolism: osteocalcin, total bone phosphatase and tartrate-resistant acid phosphatase and the establishment of correlations between these parameters and incidence of complications. It was found that in the isolated course of chronic pancreatitis there is a high (R = 0.60) statistically significant (p <0.01) correlation between the levels of osteocalcin and pancreatic elastase-1. A negative statistically significant (p <0.01) mean correlation (R = -0.49) was found between the content of tartrate-resistant acid phosphatase and age of the patients having comorbidity of chronic pancreatitis and hypertension, as well as there is a moderate correlation between the content of tartrate-resistant acid phosphatase and the duration of hypertension, which is statistically significant (R = 0.36, p <0.01). The levels of total bone phosphatase and tartrate-resistant acid phosphatase in the main group exceeded the reference values in 2.5 and 1.9 times respectively (CMU; U = 866.0; p <0.01), while in the comparison group were 2 times (total bone phosphatase) and 1.3 times higher (tartrate-resistant acid phosphatase) times, respectively (CMU; U = 821.0; p <0.01) that enables to diagnose the development of osteopenic conditions. That is, the combined course of chronic pancreatitis and hypertension should be considered as unfavourable tandem in the development of secondary osteoporosis and requires early osteoporotic screening.

scholarly journals The associations of circulating microRNA-133a with parameters of hypertension heart disease in patients with arterial hypertension and obesity

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
K Yushko ◽  
S Koval ◽  
I Snihurska ◽  
O Mysnychenko
Keyword(s):  
Heart Disease ◽  
Arterial Hypertension ◽  
Diastolic Function ◽  
Comparison Group ◽  
Left Ventricular ◽  
Main Group ◽  
Control Group ◽  
Circulating Microrna ◽  
Plasma Microrna ◽  
Lv Diastolic Function

Abstract Introduction Blood pressure (BP) elevation leads to chronical increasing left ventricular (LV) overload, LV hypertrophy (LVH), impaired LV relaxation, development of LV diastolic dysfunction (DD), left atrial (LA) enlargement, which result in development of hypertension heart disease (HDD), increased risk of atrial fibrillation and heart failure. MicroRNA-133a is one the epigenetics factor, which has cardioprotective properties, but its role in the development of HHD in hypertension patients with obesity is not well understood. Purpose The aim of the study was to investigate the circulating microRNA-133a levels in patients with hypertension and obesity and to define its associations with components of HHD. Methods The study involved 82 patients with arterial hypertension grades 2–3 and obesity (44 men and 38 women) aged 43 to 70. All patients were separate in two groups: 45 patients with HHD (main group) and 37 patients without HHD (comparison group). The control group consisted of 21 practically healthy individuals of comparable gender and age. The HHD was defined as LVH in hypertension patients with/without LV DD. The LVH was determined according to the 2018 ESC/ESH guidelines. The LV DD was determined according to the 2016 ASE/EACVI recommendations. Obesity was diagnosed at body mass index ≥30 kg/m2. Circulating plasma microRNA-133a levels were obtained by polymerase chain reaction using the CFX96 Touch System, “TaqMan microRNA Assay” and “TaqMan® Universal PCR Master Mix” reagent kits. Results The levels of microRNA-133a in main group were significantly lower than in comparison group and control group (0.133 [0.099; 0.184] vs 0.238 [0.155; 0.410], p&lt;0.05 and 0.382 [0.198; 0.474]), p&lt;0.05). In the main group 23 patients had LV DD and 25 patients had normal LV diastolic function. In patients with LV DD the levels of circulating plasma microRNA-133a were significantly lower than in patients with normal LV diastolic function (0.094 [0.067; 0.147] vs 0.152 [0.092; 0.189]), p&lt;0.05). In the main group there was a statistically significant negative correlation between microRNA-133a levels and LV mass index (R=−0.37, p&lt;0.01) and no significant correlation with ejection fraction, LA size or E/e' (averaged) ratio (p&gt;0.05). In patients of the comparison group there were not significant associations of microRNA-133a levels with LV parameters (p&gt;0.05). Conclusion The results of the study indicate a significant role of decreased circulating plasma microRNA-133a levels in patients with arterial hypertension and obesity in the pathogenesis and development of HHD and such its components as LVH and LV DD. Funding Acknowledgement Type of funding source: None

scholarly journals Influence of Nature of Infant Nutrition on Formation of Body Resistance

2021 ◽  
Vol 65 (6) ◽  
pp. 145-154
Author(s):  
T. G. Malanicheva ◽  
E. V. Agafonova ◽  
N. V. Ziatdinova ◽  
I. N. Skidan
Keyword(s):  
Incidence Rate ◽  
Respiratory Diseases ◽  
Comparison Group ◽  
Resistance Index ◽  
Community Acquired Pneumonia ◽  
Main Group ◽  
Control Group ◽  
Healthy Children ◽  
Acute Respiratory Diseases ◽  
Body Resistance

Purpose of the Study: Assessment of the influence of the type of the adapted infant milk formula in infants on the formation of the body resistance. Children Characteristics and Study Methods. 105 virtually healthy children were examined, as follows: 35 children were breastfed (control group), 70 children were formula fed including 35 children that received NENNY with prebiotics formula based on the goat milk (main group), 35 children – formulas based on the cow milk with probiotics and prebiotics (comparison group). The incidence rate of the acute respiratory diseases (ARD) as well as the number of the pneumonia histories in the infants were assessed, and the body resistance index was calculated. The laboratory assessment of the child body immunoresistance was carried out using the method of imprint smears from the nasal mucous membranes and the method of nasal washes. Results. It was determined that there were 2 times more children of the main group with no history of the acute respiratory diseases when infant than in the comparison group. In general, the good resistance (were sick 0-3 times a year) in the main group was registered in 82.9% of the children, while it was only 60% in the comparison group. The average number of the ARD cases per year was 2.3 ± 0.02 in the main group, which is 1.5 times less than in the comparison group – 3.6 ± 0.04 (p <0.05), and in 1, 3 times more than that in the control group – 1.8 + 0.03 (p<0.05). In average, the resistance index was 0.28 ± 0.02 in the main group, while it was 0.36 ± 0.03 in the comparison group, and 0.25 ± 0.02 in the control group. When studying the incidence rate of the community-acquired pneumonia in the infants, it was revealed that 2.8% of them were ill in the control group, 5.7% of them in the main group, and 8.5% in the comparison group. When feeding the child with formulas based on the goat’s milk, the level of mucosal immunity of the nasal mucosa and enzyme systems of the intraleukocyte microbicidal system is assured, which is virtually indistinguishable from the level of immunity achieved with breastfeeding. Conclusion. Adapted NENNY with prebiotics formulas can be recommended for children who are formula fed when infant in order to increase the body’s resistance and to reduce the incidence rate of the acute respiratory diseases and community-acquired pneumonia.

scholarly journals The risk of development of acute kidney injury in full-term infants with administration of methylxanthines

Pathologia ◽  
2021 ◽  
Vol 18 (2) ◽  
pp. 152-158
Author(s):  
L. S. Stryzhak ◽  
I. O. Anikin ◽  
O. V. Spakhi
Keyword(s):  
Acute Kidney Injury ◽  
Serum Creatinine ◽  
Comparison Group ◽  
Perinatal Asphyxia ◽  
Statistical Significance ◽  
Kidney Injury ◽  
Main Group ◽  
Full Term ◽  
Term Infants ◽  
Caffeine Citrate

Exploring new possibilities for the use of methylxanthines to prevent the development of acute kidney injury (AKI) in full-term infants with perinatal asphyxia. Aim: to evaluate the efficacy and safety of methylxanthines in full-term infants for the prevention and conservative treatment of acute kidney injury. Materials and methods. To test the effectiveness of the proposed method of AKI treatment, 38 infants were chosen and divided into 2 groups by random selection. Nursing and intensive care were according to current legislation (Order of the Ministry of Health of Ukraine No. 225 of March 28, 2014). The main group (n = 20) received therapy with caffeine citrate, the comparison group (n = 18) – theophylline. Both of these drugs were used to prevent the development of acute kidney injury – stage II and III according to KDIGO. Results. A significant difference in serum creatinine was found in the main group - the level of serum creatinine was higher than in the comparison group, but did not exceed the physiological norm. GFR on the 3rd day of life was higher with administration of theophylline, but in the group of caffeine did not exceed the reference values of the norm. No differences between urea levels and diuresis rates were found in the groups. The initial results indicate the lack of statistical significance when using various drugs of the methylxanthine group, namely theophylline and caffeine citrate. This is explained by the fact that in the main group 65.00 % (n = 13) of patients had AKI stage 0 according to KDIGO, and 35.00 % (n = 7) had stage I. In the comparison group, 55.56 % (n = 10) and 44.44 % (n = 8), respectively. Stages II and III in both groups of the study did not develop, the obtained data are equivalent – U = 163,00; P = 0,6296. However, the use of caffeine citrate may become a priority due to a better safety profile compared to theophylline. Caffeine is less likely to cause adverse effects in the form of non-pathological bile vomiting and has significantly lower relative risk of non-pathological bile vomiting in infants (RR 0.26 (95 % CI 0.10; 0.66)). Conclusions. Conservative methylxanthine therapy in full-term infants with perinatal asphyxia prevents the development of stages II and III of AKI according to KDIGO. However, it is necessary to continue the collection of material to increase the statistical significance, as well as to study the early and long-term consequences of this therapy.

PSYCHOVEGETATIVE PREREQUISITES FOR ARTERIAL HYPERTENSION SYNDROME INUNDERGROUND WORKERS

2021 ◽  
Author(s):  
S.V. Paramonova ◽  
◽  
N.N. Malyutina ◽  
N.S. Sedinina
Keyword(s):  
Arterial Hypertension ◽  
Cardiovascular System ◽  
Clinical Laboratory ◽  
Vegetative State ◽  
Negative Relationship ◽  
Risk Groups ◽  
Main Group ◽  
Laboratory Diagnostics ◽  
Aged People ◽  
Age Related

Abstract: We examined 109 men working at а mining enterprise exposed to occupational and psychosocial factors. The patients were divided into two groups: the main group - 60 men working in underground conditions, the conditions are assigned to classes 3.3 - 3.4; comparison group - 49 men performing ground work, whose conditions are classified as 3.2. In connection with the established diagnosis of "Syndrome of arterial hypertension" in middle-aged people of the main group, it was divided into two subgroups in terms of age - people under 45 years old (n = 20, age 38.45 ± 2.95 years), and people older 45 years old (n = 40, age 50.90 ± 1.46 years.). Purpose: to study the prerequisites for the development of hypertension based on the psychovegetative status and some changes in the biochemical and functional indicators of the CVS, depending on the age-related changes in these indicators. Materials and methods: the patient underwent a study of the psycho-vegetative state with an assessment of the level of neuropsychic stress, personal and situational anxiety, attention function, subjective reflection of psycho-vegetative distress. The state of the cardiovascular system was investigated according to the results of functional and clinical laboratory diagnostics. Results: A decrease in attention, an increase in personal anxiety and an increase in the number of psychovegetative complaints were significantly more often detected in the group of patients with hypertension (OR 7.50; 95% CI 2.39-23.58; OR 11.06 95% - CI - 4.35 - 28.10; CI 22.50; 95% CI - 7.09 - 71.41). Adaptive psychovegetative phenotypes were distinguished in two subgroups. In patients over 45 years old, a negative relationship was established between age, experience and some parameters of psycho-vegetative status, as well as a direct relationship between these parameters and some indicators of homeostasis in the diagnosis of hypertension syndrome in 95% of patients in this subgroup. Conclusions: with an increase in age and experience, there is a transformation of the adaptive psychovegetative phenotype with an inversion of connections with psychovegetative parameters against the background of increased functional disorders of the cardiovascular system. Diagnostics of the transformation of this phenotype makes it possible to assess the risk of developing arterial hypertension and contributes to the prevention of hypertension by forming risk groups.

scholarly journals STRUCTURAL AND FUCNTIONAL PARAMETERS OF THE CARDIOVASCULAR SYSTEM DURING ATRIAL FIBRILLATION IN PATIENTS AFTER STROKE

2021 ◽  
Vol 74 (3) ◽  
pp. 465-470
Author(s):  
Lyudmila A. Kamyshnikova ◽  
Olga A. Efremova ◽  
Ekaterina V. Bondarenko ◽  
Natalya I. Obolonkova ◽  
Olga A. Bolkhovitina ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Cardiovascular System ◽  
Comparison Group ◽  
Interventricular Septum ◽  
Posterior Wall ◽  
Main Group ◽  
Myocardial Mass ◽  
Stroke Patients ◽  
Functional Parameters ◽  
And Gender

The aim: To evaluate the structural and functional parameters of the cardiovascular system during atrial fibrillation (AF) in patients after a stroke. Materials and methods: In the main group, we selected 28 patients with non-valvular AF who had previously suffered an ischemic stroke (IS). The comparison group (30 people) included patients with AF without a stroke, comparable in age and gender. Results: As a result of the study, we discovered an increase in the risk of stroke with an increase in the thickness of the intima-media complex>0.9mm. The thickness of the interventricular septum was 1.19 (1.1; 1.25) in the group of patients with IS, and in the group of patients without IS – 1.09 (1.0; 1.19) cm (p = 0.019), the thickness of the LV posterior wall is greater in the main group 1.14 (1.05; 1.24) and 1.09 (1.01; 1.18) cm in the comparison group (p = 0.038). The myocardial mass index is 123.3 in the main group and 107.4 g/m2 in the comparison group (p = 0.41), which indicates left ventricle (LV) hypertrophy in the main group. Conclusions: thus, during AF in stroke patients, changes in the following structural and functional parameters of the cardiovascular system were discovered: an increase in the thickness of the interventricular septum, thickness of the posterior wall of the LV, and in the thickness of the intima-media complex.

scholarly journals THE EXPERTISE OF THE CAUSAL RELATIONSHIP BETWEEN THE DEVELOPMENT OF ARTERIAL HYPERTENSION WITH PARTICIPATION IN WORKS FOR LIQUIDATION OF THE CONSEQUENCES OF CHORNOBYL NPP ACCIDENT IN REMOTE POSTACCIDENTAL PERIOD

2020 ◽  
Vol 25 ◽  
pp. 543-557
Author(s):  
V. Sushko ◽  
◽  
O. Tatarenko ◽  
O. Kolosynska ◽  
D. Hapieienko ◽  
...  
Keyword(s):  
Arterial Hypertension ◽  
Radiation Exposure ◽  
Causal Relationship ◽  
Inpatient Treatment ◽  
Comparison Group ◽  
Main Group ◽  
Vascular Events ◽  
Permanent Disability ◽  
Medical Expertise ◽  
Relationship Of

Loss of health and work ability, as well as deaths from diseases of the circulatory system (DCS), first of all arterial hypertension (AH), due to radiation exposure (RE) in the conditions of Chernobyl catastrophe (ChC) in the performance of professional, military or official duties and / or living on radiation-contaminated areas, additional exposure not through their own fault but due to a radiation accident, caused the development of a special form of medical expertise as part of the of medical social protection system for these suffered contingents. Objective: to optimize decision-making criteria for the expert estimation of the casual relationship between development and progression of AH under the influence of RE in clean-up workers of the Chornobyl NPP accident (CWs) in the remote postaccidental period based on the study of odds ratio (OR) of the course of the disease. Material and methods. A retrospective analysis of the structure of 16073 cases of victims of the Chornobyl NPP (ChNPP) accident, considered by the Central Interagency Expert Commission of Ministry of Health of Ukraine for diseases, reason of disability and death causal relationship to ChNPP accident (CIEC) during 2014–2016, allowed to form a group of 401 cases of CW with AH to determine the OR of the course of the disease. The main group consisted of 330 CWs for whom the development of AH has a causal relationship with the participation in the work for liquidation consequences of the Chornobyl NPP accident (WLAc), the comparison group – 71 CWs in respect of whom a negative expert decision was made. There were not significant differences between both groups of CWs in dose of external radiation exposure (DERE) in the main group – (0.155 ± 0.085) Sv, in CWs of the comparison group – (0.135 ± 0.086) Sv (р = 0.868). Results. In the remote postaccidental period, HSC take the second place (39.62 %) in the structure of medical expertise of the causal relationship of the diseases development and progression with RE for all categories of victims of the Chernobyl accident. The share of cases of AH was 28.4% of the total number of cases considered CWs. In the structure of cases of relationship of diseases of CWs that led to death, the share of AH was 17.8 %. In CWs the main group the AH developed in (9.4 ± 6.2) years after participation in WLAc, which is on average 6 years earlier than in the comparison group (р < 0.001). AH in the main group of CWs developed at the age of 5.8 years younger than in the comparison group (р = 0.0005). The need for inpatient treatment come 8.6 years earlier (14.6 ± 7.7 years) than in CWs comparison group (р < 0.001). At DERE 0,05 Sv and over, increases the probability of development and progression of AH that has causal relationship with participation in the WLAc. For medical expertise of the causal relationship of the AH development and progression with WLAc at DERE 0.20 Sv and over the significant evidence value have the next criteria: terms Somatoform Vegetative (autonomic) Dysfunction (SVD) development (within 3,5 years) and its transformation into AH (within 7 years), verification of the AH diagnosis (within 9,5 years), inpatient treatment for SVD or AH (within 15 years), vascular events (Acute Cerebrovascular Accident – Stroke (ACVA) – within 24 years after participation in the WLAc or 11 years after the AH diagnosed, myocardial infarction (MI) – within 22 years after participation in the WLAc or 10.5 years after the AH diagnosed), the establishment of permanent disability. Conclusion: Radiation factor has an evidence influence on the development and progression of AH in CWs. Criteria of the development and progression of AH in CWs can be used for evidence-based medical expertise for estimation of the causal relationship of the disease with the WLAc in the remote post accidental period at DERE more than 0.20 Sv. Key words: ionizing radiation, arterial hypertension, clean-up workers of Chornobyl NPP accident, medical expertise, Chornobyl catastrophe.

scholarly journals Heart remodeling in elderly patients with isolated systolic arterial hypertension and chronic heart failure with preserved left ventricular ejection fraction

2021 ◽  
Vol 23 (3) ◽  
pp. 331-337
Author(s):  
S. O. Sheiko ◽  
N. O. Kolb
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Ejection Fraction ◽  
Elderly Patients ◽  
Arterial Hypertension ◽  
Comparison Group ◽  
Left Ventricular ◽  
Main Group ◽  
Volume Index ◽  
Left Ventricular Ejection

The aim of the work was to study the structural and functional state of the left ventricle (LV) in elderly patients with isolated systolic arterial hypertension (ISAH) and chronic heart failure with preserved ejection fraction (CHF with PEF). Materials and methods. After receiving an informed consent, 134 elderly patients with ISAH were enrolled in the study. The main group included 91 patients aged 71.1 ± 3.5 years with ISAH and ejection fraction (EF) of the LV >50 % and a level of natriuretic peptide (NT-proBNP) >125 pg/ml. Among them, there were 61 women (67 %) and 30 (33 %) men. The comparison group consisted of 43 patients (27 women and 16 men aged 70.4 ± 3.7 years) with ISAH, LV EF >50% and NT-proBNP <125 pg/ml. The geometric changes of the LV were evaluated taking into account the LV myocardial mass index and the relative LV wall thickness. Results. Cardiac remodeling in elderly ISAH patients with CHF and PEF was represented by the following geometric variants of the LV. In the main group patients, concentric LV hypertrophy (LVH) prevailed – 73 (80.2 %) patients, while in the comparison group, concentric modeling (CR) – 25 (58.1 %) patients (P < 0.01 by criterion χ2). CR in the ISAH patients with CHF and PEF was diagnosed in 18 (19.8 %) cases. Concentric LVH was verified in 18 (41.9 %) patients of the comparison group (P < 0.01). It was determined that the hyperfunction of the left atrium (LA) in the patients with ISAH without CHF was compensatory. The maximum volume index of the LA (VILAmax.) in these patients was in the range of 27–32 ml/m2. Hyperfunction of the LA in the ISAH patients with CHF and PEF was accompanied by a statistically significant increase in VILAmax. over 34 ml/m2. Conclusions. The prevalence of ISAH among elderly patients is 35.6 %. The formation of a hypertensive heart in the ISAH patients with CHF and PEF is characterized by a predominant concentric LVH (80.2 %) and hyperfunction of the LA. A significant increase in the LA volumes testifies to increase in its contribution to the LV filling with the formation of LV diastolic dysfunction. The presence of concentric LVH and an increase in VILAmax. ≥34 ml/m2 is a criterion for identifying individuals at high and very high risk among elderly ISAH patients with CHF and PEF.

scholarly journals Complicated destructive appendicitis: finding the optimal treatment method

2021 ◽  
Vol 102 (5) ◽  
pp. 751-756
Author(s):  
I S Malkov ◽  
T A Mamedov ◽  
M I Shakirov ◽  
V A Filippov
Keyword(s):  
Comparison Group ◽  
Surgical Intervention ◽  
Morphological Changes ◽  
Statistical Significance ◽  
Surgical Techniques ◽  
Treatment Method ◽  
Intestinal Wall ◽  
Main Group ◽  
Wound Complications ◽  
Lengths Of Stay

Aim. To analyze the current practice for the surgical treatment of destructive acute appendicitis complicated by typhlitis and periappendicular abscess. Methods. This study analyzed the treatment outcomes in 84 patients with acute destructive appendicitis aged 18 to 79 years who were treated in the Department of Surgery No. 2 of the City Clinical Hospital No. 7 of Kazan between 2016 and 2021 years. According to the method for completion of surgical intervention, patients were divided into 2 groups, similar in age, duration of the disease and morphological changes in the appendix. In the comparison group, 54 patients had the surgical intervention completed by gauze-glove drainage of the appendix bed. In 30 patients of the main group, the appendix stump and the adjacent intestinal wall was covered with a Tachocomb plate. Then the VAC system with the Vivano device and supplies from Hartmann Group (Germany) was connected. The statistical significance of the differences between the indicators was assessed by using the Student's t-test. Results. The analysis of the surgical techniques used showed that in the main group, postoperative wound complications decreased by 3 times (23.3% of patients, p=0.04), intra-abdominal fluid collections decreased by 2 times (6.7% of patients, p=0.02), the hospital lengths of stay decreased by 1.8 times (p=0.02) compared with the comparison group. Conclusion. The use of ligature appendectomy in combination with plastic closure of the appendix stump with a TachoComb and the technology of local vacuum-assisted laparostomy in patients with destructive appendicitis complicated by periappendicular abscess contributes to a 3-fold reduction in wound postoperative complications and reduces the hospital lengths of stay in this group of patients by 1.8 times.

scholarly journals Features of the quality of life in children with food allergy

2021 ◽  
Vol 24 (4) ◽  
pp. 236-242
Author(s):  
Denis S. Fugol ◽  
Lyudmila A. Strozenko ◽  
Yuri F. Lobanov ◽  
Igor I. Voronin ◽  
Vsevolod V. Pozhenko
Keyword(s):  
Quality Of Life ◽  
Food Allergy ◽  
Comparison Group ◽  
Clinical Manifestations ◽  
Elimination Diet ◽  
Main Group ◽  
Healthy Children ◽  
Food Borne ◽  
Safe Food

Introduction. Food allergy (FA) being a clinically heterogeneous condition, the only treatment for which is a strong elimination diet. The need to exclude one or more foods from the diet, constant monitoring of the diet, anxiety and excitement about the exacerbation of allergic symptoms lead to a significant decrease in the quality of life. Materials and methods. The study included thirty eight 2-7 year children patients with various clinical manifestations of FA (atopic dermatitis, allergic and alimentary colitis, food-borne dermatitis). The comparison group consisted of twenty seven healthy children matched by age. The quality of life in all children was assessed using the Pediatric Quality of Life - PedsQLTM4.0 questionnaire. Results. All FA children patients showed a significant decrease in the quality of life in terms of such indicators as emotional functioning (60.2 in the main group and 83.5 in the comparison group), social functioning (77.9 in the main group and 88.1 in the comparison group), role functioning or kindergarten functioning (FDS) (77.5 in the main group and 84.9 in the comparison group) and psycho-social health (69.3 in the main group and 85.5 in the comparison group). The overall score in assessing the quality of life is significantly lower in the group of FA children (71 in the main group and 87 in the comparison group). Conclusion. To improve the quality of life of children with FA, there is needed a comprehensive individual approach including both psychological support for the child and his family members, and the solution of issues with the provision of «safe» food in children’s educational institutions.

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