scholarly journals Electronic cigarettes and lung toxicity

2017 ◽  
Vol 5 (19) ◽  
pp. 16 ◽  
Author(s):  
Terrance Rodrigues ◽  
Eric Deal ◽  
Kenneth Nugent ◽  
J. Drew Payne

The use of electronic cigarettes (e-cigarettes) in the United States has steadily increasedsince their introduction into the market in 2007. These devices deliver nicotine through thevaporization of a liquid which contains a vehicle (propylene glycol or glycerin), artificialflavoring, and nicotine. The combustion of these liquids creates a vapor containing particulates,multiple chemicals, and nicotine. The long-term safety of these products is unknown. Studiesin healthy, non-smoking volunteers and smokers with no clinical pulmonary disease havedemonstrated that the inhalation of e-cigarette vapor has minimal short-term effects onpulmonary function. The exposure of cell cultures to e-cigarette liquid or aerosols has beenshown to reduce cell viability, induce cytokine production, and cause oxidative stress. Theexposure of animals (mice and rats) to e-cigarette aerosols induces inflammatory responsesin the lungs and delays the clearance of bacterial and viral challenges. There are a smallnumber of case reports of patients developing acute pulmonary toxicity following the use ofe-cigarettes. Two patients have developed lipoid pneumonia following the use of e-cigarettesfor 3 and 7 months. Finally, several studies suggest that patients with chronic lung diseasewho switch from tobacco cigarettes to e-cigarettes can have improvement in lung function(asthmatics) and a reduction in the number of exacerbations (chronic obstructive pulmonarydisease). Clearly, the public and the medical profession need more information about thelong-term complications associated with the use of e-cigarettes and their benefit in smokingcessation efforts.Keywords: electronic

Author(s):  
Craig D. Croskery ◽  
Kathleen Sherman-Morris ◽  
Michael E. Brown

AbstractThe coronavirus disease 2019 (COVID-19) pandemic resulted in unprecedented challenges that dramatically affected the way of life in the United States and globally in 2020. The pandemic also made the process of protecting individuals from tornadoes more challenging, especially when their personal residence lacks suitable shelter, particularly for residents of mobile homes. The necessity of having to shelter with other families – either in a public shelter or at another residence – in order to protect themselves from a tornado threat conflicted with the advice of public health officials who recommended avoiding public places and limiting contact with the public to minimize the spread of COVID-19. There was also a perception that protecting against one threat could amplify the other threat. A survey was undertaken with the public to determine the general viewpoint to see if that was indeed the case.The results found that it was possible to attenuate both threats provided that careful planning and actions were undertaken. Understanding how emergency managers should react and plan for such dual threats is important to minimize the spread of COVID-19 while also maintaining the safety of the public. As there was no precedence for tornado protection scenarios amidst a pandemic, both short-term and long-term recommendations were suggested which may also be useful in future pandemic situations.


Author(s):  
S. Dorofeev

The main idea of this article is to identify the strategic interests of Russia and the United States and their feasibility taking into account the operational institutions and historical experience of development in the Central Asia. Using in this analysis the concept of strategic interest the author comes to the following conclusions. Firstly, realization of the long-term interests is prevented by the will to obtain short-term benefits. Secondly, a discrepancy between the strategic interest and the “national interest” should be underlined since the latter has a too broad meaning and is often perceived only in the context of the public interest.


2020 ◽  
Vol 15 (4) ◽  
pp. 24-27
Author(s):  
Max Deschner ◽  
Marcel Tunks ◽  
Cory Yamashita

In recent years there has been a proliferation in the practice of vaping to consume nicotine-and cannabis-based products. While evidence on the benefits and risks of electronic cigarettes (e-cigarettes) is evolving, this brief primer highlights important new information about vaping for clinicians, researchers and the public. In 2018, the Canadian government passed legislation to regulate tobacco and vaping products. We discuss evidence comparing e-cigarettes versus nicotine replacement therapy for smoking cessation and highlight limitations of this body of research. While e-cigarettes are felt to contain fewer toxins than cigarettes, the long-term effects of vaping remain unknown. Emerging data demonstrates associations between vaping and acute and chronic lung disease. We discuss the emergence of an outbreak of severe lung injury associated with e-cigarette use in the United States and similar cases in Canada. Finally, we review evidence demonstrating the growing prevalence of vaping and smoking amongst Canadian youth. RESUMECes dernières années, on a assisté à une prolifération de la pratique de la vaporisation pour consommer des produits à base de nicotine et de cannabis. Alors que les preuves sur les avantages et les risques des cigarettes électroniques (e-cigarettes) évoluent, ce bref aperçu met en lumière de nouvelles informations importantes sur le vaping pour les cliniciens, les chercheurs et le public. En 2018, le gouvernement canadien a adopté une loi pour réglementer les produits du tabac et les produits à base de vapeur. Nous examinons les données comparant les e-cigarettes et les thérapies de remplacement de la nicotine pour le sevrage tabagique et soulignons les limites de ce corpus de recherche. Bien que l’on estime que les e-cigarettes contiennent moins de toxines que les cigarettes, les effets à long terme des vapeurs restent inconnus. Les données émergentes démontrent des associations entre l’inhalation de vapeurs et les maladies pulmonaires aiguës et chroniques. Nous discutons de l’émergence d’une épidémie de lésions pulmonaires graves associées à l’utilisation des e-cigarettes aux États-Unis et de cas similaires au Canada. Enfin, nous passons en revue les preuves démontrant la prévalence croissante des vapeurs et du tabagisme chez les jeunes Canadiens.


2017 ◽  
Vol 9 (1) ◽  
pp. 168
Author(s):  
Md Mostafizur Rahman ◽  
Mahmud Uz Zaman

Pharmaceuticals agglomerations consistently use their brand image and versatile product portfolios to consolidate their position in the financial sector, which is evident in their continuous profit making and expansion in market share. This paper explores the short-term and long-term investment attractiveness through ‘consumer centric decision’ approach in two selected pharmaceutical companies, Renata Limited and Orion Pharma Limited, of Bangladesh over the last three years’ period. This research adopts a systematic approach which primarily addresses the various concerns of investors to illustrate the decision-making process of the existing and future investors. Using primarily domestic transaction data, this study explores how the leading pharmaceuticals companies of Bangladesh effectively use the wide array of drug portfolios mix with appropriate branding techniques to increase their financial profit and market share simultaneously. Both SWOT analysis and Porters Five Forces Model explore the business analysis of Renata Limited in compare to Orion Pharma Limited that provides a conclusion regarding investors’ decision to invest in Renata Limited. Considering the financial analysis, Renata’s financial liquidity is not very satisfactory and could have been improved further if management is prudent on financial strategy settings. Findings of the business analysis indicate that Renata Limited would be a good investment choice for existing and prospective shareholders based on its opportunities for long term and short term growth and further expansion in developing the market. The results suggest that even lower liquidity coupled with higher interest borrowings can be balanced by posing positive picture to the public shareholders by returning the positive dividend to them.


2003 ◽  
Vol 20 (3-4) ◽  
pp. 46-82
Author(s):  
Fathi Malkawi

This paper addresses some of the Muslim community’s concerns regarding its children’s education and reflects upon how education has shaped the position of other communities in American history. It argues that the future of Muslim education will be influenced directly by the present realities and future trends within American education in general, and, more importantly, by the well-calculated and informed short-term and long-term decisions and future plans taken by the Muslim community. The paper identifies some areas in which a wellestablished knowledge base is critical to making decisions, and calls for serious research to be undertaken to furnish this base.


Modern Italy ◽  
2008 ◽  
Vol 13 (2) ◽  
pp. 135-153 ◽  
Author(s):  
Raffaella A. Del Sarto ◽  
Nathalie Tocci

Focusing on Italy's Middle East policies under the second Berlusconi (2001–2006) and the second Prodi (2006–2008) governments, this article assesses the manner and extent to which the observed foreign policy shifts between the two governments can be explained in terms of the rebalancing between a ‘Europeanist’ and a transatlantic orientation. Arguing that Rome's policy towards the Middle East hinges less on Italy's specific interests and objectives in the region and more on whether the preference of the government in power is to foster closer ties to the United States or concentrate on the European Union, the analysis highlights how these swings of the pendulum along the EU–US axis are inextricably linked to a number of underlying structural weaknesses of Rome's foreign policy. In particular, the oscillations can be explained by the prevalence of short-term political (and domestic) considerations and the absence of long-term, substantive political strategies, or, in short, by the phenomenon of ‘politics without policy’ that often characterises Italy's foreign policy.


2018 ◽  
Vol 17 (2) ◽  
pp. 783-810
Author(s):  
Angélica Pott de Medeiros ◽  
Giulia Xisto de Oliveira ◽  
Reisoli Bender Filho

Resumo: O cenário de instabilidade política, a recessão econômica e as mudanças nas regras de concessão de crédito pautaram o objetivo de examinar o relacionamento do crédito consignado, por segmento de concessão, com variáveis macroeconômicas, caso do consumo, da produção industrial e do produto agregado, na última década (2007-2017). Os resultados foram obtidos por meio da estimação do vetor de correção de erros, funções de impulso-resposta e decomposição da variância, possibilitando a análise das relações de curto e de longo prazo entre as séries temporais e indicaram que as diferentes modalidades do crédito consignado implicam efeitos distintos sobre as variáveis econômicas em curto prazo. O segmento de aposentados e pensionistas impacta positivamente ambas as variáveis analisadas, com destaque para os bens de consumo das famílias. Já a concessão ao setor privado, embora represente a menor parcela do crédito consignado concedido, mostrou elevada sensibilidade a alterações na oferta dessa modalidade de crédito, enquanto que o crédito ao setor público, de maior participação, apresentou efeitos reduzidos e de curta duração.Palavras-chave: Crédito consignado. Segmentos. Economia brasileira. Payroll loans: segments and economic effects Abstract: The environment of political instability, economic recession and changes in the rules of granting credit were guiders to aim to examine the payroll loans relationship, by concession segment, with macroeconomic variables, case of consumption, industrial production and aggregate product, in the last decade (2007-2017). The results obtained by error correction vector estimation, and functions of impulse-response and variance decomposition, making it possible to analyze the short- and long-term relationships between the time series and indicated that the different modalities of payroll loans imply different effects on economic short-term variables. With retirees and pensioners segment positively impact on both analyzed variables, highlighting the household consumption goods. The concession to the private sector, although it represents the smallest portion of payroll loans granted, it showed high sensitivity to the changes of this modality. About credit to the public sector, which has the biggest portion, it showed reduced and short-term effects.Keywords: Payroll loans. Segments. Brazilian economy.


2017 ◽  
Vol 22 (02) ◽  
pp. 232-235
Author(s):  
Seigo Suganuma ◽  
Kaoru Tada ◽  
Daiki Yamamoto ◽  
Hiroyuki Tsuchiya

The Galeazzi-equivalent fracture is a rare injury that occurs in children. The most important issue is the distal ulnar epiphyseal injury. Although there have been some case reports, most of them performed only short term follow-up. This article describes two cases of this fracture with long term follow-up until epiphyseal closure. First case is a 12-year-old girl who sustained a Galeazziequivalent fracture of her right forearm and underwent emergency surgery. At follow-up of 5 years and 10 months postsurgery, radiographs show ulnar growth arrest of one mm and she has mild pain. Second case is a 15-year-old boy who sustained an open Galeazzi-equivalent fracture of his left forearm and underwent emergency surgery. At follow-up of 3 years and 3 months postsurgery, radiographs show no growth arrest of the distal ulna. He has no residual complaint. Long term follow-up is absolutely necessary to monitor ulnar growth.


2018 ◽  
Vol 25 (2) ◽  
pp. 169-197
Author(s):  
Mitchell B. Lerner

The election of Donald J. Trump unsettled many areas of U.S. foreign policy, but few more than the nation’s relationship with Korea. This article argues that the Trump administration’s vision for the world represents a stark break from the tradition of liberal internationalism and instead seeks to take the United States down a path that reflects the modern business practices of giant American corporations. A suitable label for this vision, as the following pages will show, is “Walmart unilateralism.” This framework abandons the traditional American policies of nation building and alliances based on shared ideological values. Instead, it embraces a more short-term approach rooted in financial bottom lines, flexible alliances and rivalries, and the ruthless exploitation of power hierarchies. This new approach, this article concludes, may dramatically transform the American relationship with Korea. Walmart unilateralism in Korea almost certainly will have some short-time positive ramifications for the United States, but its larger failure to consider the history and values of the people living on the Korean Peninsula may generate serious long-term problems for the future experience of the United States in the region.


Author(s):  
Franz Neumann

This chapter considers a variety of methods of treating Germany. The main objective of the United Nations in the treatment of Germany is to prevent it from ever again becoming a threat to the security of the world. The problem of securing this objective could be approached through destruction of Germany's industrial potential, destruction of Germany as a political entity, and removal from German society of the causes of aggression. The chapter shows that the first two solutions should be deferred until it is clear that the third alternative proves unworkable. In order to eliminate the causes of aggressiveness in German society, temporary and long-term disabilities should be imposed upon Germany. The chapter also examines the causes of German aggression, the United States' policy toward Germany, short-term measures during the period of military government, conditional measures during the probationary period, and permanent impositions upon Germany.


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